Abstract:
OBJECTIVE:To investigate the risk of cancer associated with exposure to air pollution among bus drivers and tramway employees. METHODS:A retrospective cohort study of 18,174 bus drivers or tramway employees in Copenhagen in the period 1900-94. Data on employment were obtained from company files. Information on cancer was obtained from the Danish Cancer Registry. RESULTS:Findings showed that bus drivers or tramway employees had an increased risk of all malignant neoplasms (standardised incidence ratio (SIR) 1.24, 95% confidence interval (95% CI) 1.19 to 1.30). The relative risk was significantly increased for both men and women (SIR 1.24, 95% CI 1.19 to 1.30 and 1.28, 1.06 to 1.53, respectively). People employed for < 3 months had no increased risk of cancer (1.04, 0.81 to 1.31). For men who were employed for > 3 months the risk of lung cancer (1.6, 1.5 to 1.8), laryngeal cancer (1.4, 1.0 to 1.9), kidney cancer (1.6, 1.3 to 2.0), bladder cancer (1.4, 1.2 to 1.6), skin cancer (1.1, 1.0 to 1.2), pharyngeal cancer (1.9, 1.2 to 2.8), rectal cancer (1.2, 1.0 to 1.5) and liver cancer (1.6, 1.2 to 2.2) was significantly increased. For women employed for > 3 months the risk of lung cancer was significantly increased (2.6, 1.5 to 4.3). CONCLUSION:This cohort study shows that bus drivers and tramway employees are at an increased risk of developing several types of cancer. This might be due to the exposure to air pollution during working hours or to other risk factors, primarily smoking.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Soll-Johanning H,Bach E,Olsen JH,Tüchsen Fdoi
10.1136/oem.55.9.594subject
Has Abstractpub_date
1998-09-01 00:00:00pages
594-8issue
9eissn
1351-0711issn
1470-7926journal_volume
55pub_type
杂志文章abstract:OBJECTIVES:To investigate the relation between fluctuations in personal exposure to nitrogen dioxide (NO(2)) in school children and changes in outdoor NO(2) concentrations. METHODS:114 Asthmatic school children aged 7-12 years were recruited from the Southampton area. Weekly average personal exposures to NO(2) were me...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.7.472
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The pathogenesis of cataract is influenced by a number of factors including oxidative stress. Glutathione S-transferase (GST) catalyses the nucleophilic addition of the thiol of GST to electrophilic acceptors. It is important for detoxification of xenobiotics in order to protect tissues from oxidative damage...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.022343
更新日期:2006-07-01 00:00:00
abstract:AIMS:To evaluate the mortality experience of a cohort of employees in the UK silica sand industry exposed to respirable crystalline silica (RCS). METHODS:A retrospective cohort mortality study followed all workers to 2001 with at least one year's employment at one of seven UK silica sand producing quarries between 195...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.017731
更新日期:2005-07-01 00:00:00
abstract::The association between occupational exposure to airway irritants and the prevalence of chronic respiratory symptoms and level of lung function, and whether these associations were modified by airway hyperresponsiveness, smoking, and a history of allergy were studied in 668 workers from synthetic fibre plants. Respira...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.1.3
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:To obtain knowledge about the use and distribution of hazardous chemicals in Danish industry. This knowledge is used to regulate the occupational environment and prevent hazardous exposure. METHODS:A national survey on the use of chemicals was carried out in 1989 in a stratified sample of 1448 Danish busine...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.7.454
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of a self-management intervention (including an eHealth module), compared with usual care, in employees with chronic non-specific complaints of the arm, neck or shoulder (persisting >3 months). METHODS:Participants were randomised into the self-management group (SG) or usual car...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2015-103089
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:A growing interest in reducing occupational sitting has resulted in public health efforts to encourage intermittent standing in workplaces. However, concerns have been raised that standing for prolonged periods may expose individuals to new health hazards, including lower limb atherosclerosis. These concerns...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2020-106905
更新日期:2020-11-03 00:00:00
abstract:OBJECTIVES:Studies in traditional paper mills have indicated an excess cancer risk, and mutagenic compounds have been identified in the industry. No studies have reported on risk of cancer in paper recycling. Therefore the cancer incidence in Danish paper recycling mills was investigated. METHODS:5377 employees in fiv...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.10.729
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVES:Prenatal occupational exposure to pesticides has been associated with male reproductive tract abnormalities. Little is known about the possible impact of non-occupational pesticide exposure on fetal and child development in the general population. Using data from a nationwide birth cohort, we aimed to assess...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-105801
更新日期:2019-09-01 00:00:00
abstract:AIMS:To investigate the effects of smoking and personal hygienic behaviour on blood lead (BPb) and free erythrocyte protoporphyrin levels (FEP) in lead exposed workers. METHODS:Subjects were 105 lead exposed male workers in a battery recycling plant during the years 2000-03. BPb and FEP were measured as part of the on...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.019513
更新日期:2005-05-01 00:00:00
abstract:OBJECTIVES:The main objective was to study the acute vascular effects in the hands of normal healthy subjects of a complex vibration spectrum similar to that generated by many industrial hand held tools. The effects of repeated bouts of vibrations and alterations in the intensity of vibration were also studied. METHOD...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.10.663
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVES:A previous study of the short term effects of air pollution in London from April 1987 to March 1992 found associations between all cause mortality and black smoke and ozone, but no clear evidence of specificity for cardiorespiratory deaths. London data from 1992 to 1994 were analysed to examine the consisten...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.4.237
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVES:To investigate whether an increased risk of cardiovascular disease might be caused by increased arrhythmogeneity and by unfavourable changes in autonomic cardiac control the changes in the occurrence of premature complexes (PVCs) and in heart rate variability (HRV) were studied in subjects who started to wor...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.10.678
更新日期:2001-10-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of chronic exposure to lead on the peripheral nervous system in lead workers. METHODS:Nerve conduction velocity and electromyographic studies were performed on 31 lead workers of a battery recycling factory and 31 sex and age matched controls. 25 cases with mild distal extensor weakn...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.6.415
更新日期:1995-06-01 00:00:00
abstract:OBJECTIVE:Occupational workload has been associated with an increased risk of osteoarthritis. The objective was to further examine the association between workload and occurrence of osteoarthritis and in particular to study whether heavy workload has similar importance as a causative factor for osteoarthritis of the hi...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2007.033365
更新日期:2008-04-01 00:00:00
abstract:AIMS:To investigate the possible interaction between occupational risk factors and genotype for glutathione S-transferases M1 and T1 (GSTM1 and GSTT1) in renal cell cancer (RCC). METHODS:One hundred patients with RCC and 200 outpatient controls were enrolled at Parma University Hospital. The polymorphisms of glutathio...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.10.789
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:To explore the relationship between occupations and specific occupational exposures and oesophageal cancer (OC) by histological type. METHODS:A multicentre hospital-based case-control study was conducted in two Mediterranean provinces of Spain. Occupational, sociodemographic and lifestyle information was col...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2007.037929
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Previous studies of the risk of heart disease after shift work reached different estimates and review authors disagree about the validity of some of the studies. A cross sectional study showed that shift workers had a higher prevalence of nearly every unfavourable work environment factor investigated. Confli...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.026716
更新日期:2006-07-01 00:00:00
abstract::: This systematic review and meta-analysis aimed to examine whether working beyond the standard working hours was associated with a greater risk of depressive disorder among workers included in published prospective studies. This manuscript was prepared according to the PRISMA guideline checklist. A database search wa...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/oemed-2016-103845
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:We used data from a large, population-based case-control study in Maine, New Hampshire, and Vermont to examine relationships between occupation, industry and bladder cancer risk. METHODS:Lifetime occupational histories were obtained by personal interview from 1158 patients newly diagnosed with urothelial ca...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2009.052571
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVES:The study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as surrogates for exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). METHODS:The report included workers exposed to diesel exhausts (low PAH exposure level, n = 39) as well as those exposed t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041418
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVES:Agricultural workers are known to have occupational skin diseases. The prevalence and pattern of skin diseases are unknown in Taiwanese fruit farmers. The objective of this study is to determine the work exposure, prevalence of skin diseases, and sensitivity to common skin allergens and agricultural chemical...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.6.427
更新日期:1996-06-01 00:00:00
abstract::Although the neurological and cardiovascular effects of Freons have been extensively described, the respiratory effects have been less well documented. We report four cases of occupational asthma following accidental exposure to bromochlorodifluoromethane (Halon 1211) due to release of the contents of a fire extinguis...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.009837
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Natural rubber latex allergy can cause skin and respiratory symptoms The aim of this study was to evaluate the prevalence and incidence of latex related symptoms and sensitisation among a large group of healthcare workers in Trieste hospitals, followed for three years before and after the introduction of pow...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2003.011460
更新日期:2006-02-01 00:00:00
abstract::A cohort of 4320 uranium miners in West Bohemia who started work at the mines during 1948 to 1959 and worked there for at least four years were followed up to the end of 1990 to determine cause specific mortality risks in relation to exposures in the mines. The miners had experienced high radon exposures, on average 2...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.5.308
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVES:Hexachlorobenzene (HCB) is a highly lipophilic organochlorine compound of widespread environmental occurrence, that accumulates in the biological system. It affects the porphyrine metabolism, thyroid hormones, and the liver function in animals. Although HCB is one of the most common organochlorine compound i...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.3.172
更新日期:2001-03-01 00:00:00
abstract:CONTEXT:More than 400,000 workers annually receive a measurable radiation dose and may be at increased risk of radiation-induced leukaemia. It is unclear whether leukaemia risk is elevated with protracted, low-dose exposure. OBJECTIVE:We conducted a meta-analysis examining the relationship between protracted low-dose ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1136/oem.2009.054684
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:To evaluate the risk of cancer and other diseases among workers engaged in aircraft manufacturing and potentially exposed to compounds containing chromate, trichloroethylene (TCE), perchloroethylene (PCE), and mixed solvents. METHODS:A retrospective cohort mortality study was conducted of workers employed f...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.9.581
更新日期:1999-09-01 00:00:00
abstract:OBJECTIVES:To examine the association of immune cell number and function with occupational exposure to substances contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). METHODS:A cross sectional medical survey. The exposed participants were employed at two chemical plants between 1951 and 1972 in the manufactur...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.11.742
更新日期:1998-11-01 00:00:00
abstract:AIMS:To evaluate an epidemiological approach to a national noise hazard surveillance strategy, and report current exposure levels in the Danish workplace. METHODS:A study base of 840 companies in 10 selected high risk industries in the largest county in Denmark was identified from a national register. Noise exposure w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.012757
更新日期:2004-10-01 00:00:00