Abstract:
OBJECTIVE:This study investigated the association between long-term exposure to black smoke (BS) air pollution and mortality in two related Scottish cohorts with 25 years of follow-up. METHODS:Risk factors were collected during 1970-1976 for 15331 and 6680 participants in the Renfrew/Paisley and Collaborative cohorts respectively. Exposure to BS during 1970-1979 was estimated by inverse-distance weighted averages of observed concentrations at monitoring sites and by two alternative spatial modelling approaches which included local air quality predictors (LAQP). RESULTS:Consistent BS-mortality associations (per 10 μg m(-3) increment in 10-year average BS) were observed in the Renfrew/Paisley cohort using LAQP-based exposure models (all-cause mortality HR 1.10 (95% CI 1.04 to 1.17); cardiovascular HR 1.11 (1.01 to 1.22); ischaemic heart disease HR 1.13 (1.02 to 1.25); respiratory HR 1.26 (1.02 to 1.28)). The associations were largely unaffected by additional adjustment for area-level deprivation category. A less consistent and generally implausible pattern of cause-specific BS-mortality associations was found for inverse-distance averaging of BS concentrations at nearby monitoring sites. BS-mortality associations in the Collaborative cohort were weaker and not statistically significant. CONCLUSIONS:The association between mortality and long-term exposure to BS observed in the Renfrew/Paisley cohort is consistent with hypotheses of how air pollution may affect human health. The dissimilarity in pollution-mortality associations for different exposure models highlights the critical importance of reliable estimation of exposures on intraurban spatial scales to avoid potential misclassification bias.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Yap C,Beverland IJ,Heal MR,Cohen GR,Robertson C,Henderson DE,Ferguson NS,Hart CL,Morris G,Agius RMdoi
10.1136/oemed-2011-100600subject
Has Abstractpub_date
2012-12-01 00:00:00pages
916-24issue
12eissn
1351-0711issn
1470-7926pii
oemed-2011-100600journal_volume
69pub_type
杂志文章abstract:AIMS:To evaluate an epidemiological approach to a national noise hazard surveillance strategy, and report current exposure levels in the Danish workplace. METHODS:A study base of 840 companies in 10 selected high risk industries in the largest county in Denmark was identified from a national register. Noise exposure w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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abstract:BACKGROUND:Few studies have investigated cancer risks in carbon black workers and the findings were inconclusive. METHODS:The current study explores the mortality of a cohort of 1535 male German blue-collar workers employed at a carbon black manufacturing plant for at least one year between 1960 and 1998. Vital status...
journal_title:Occupational and environmental medicine
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doi:10.1136/oem.2006.026526
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析,评审
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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doi:10.1136/oem.55.1.31
更新日期:1998-01-01 00:00:00
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:Occupational and environmental medicine
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更新日期:2015-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103597
更新日期:2016-08-01 00:00:00
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journal_title:Occupational and environmental medicine
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更新日期:2015-05-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.7.453
更新日期:2001-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.6.386
更新日期:1994-06-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.013102
更新日期:2005-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-12-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
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更新日期:2006-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
doi:10.1136/oemed-2018-105310
更新日期:2019-01-01 00:00:00