Abstract:
BACKGROUND:Controversy still exists about the breast carcinogenic properties in humans of environmental xenoestrogens (organochlorines), justifying new investigations. AIMS:To compare the blood levels of total dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB) in samples collected at the time of breast cancer discovery, in order to avoid the potential consequences of body weight change (after chemotherapy or radiotherapy) on the pesticide residue levels. METHODS:Blood levels of HCB and total DDT (we calculated total DDT concentrations by adding all DDT and DDE isomers) were compared in 159 women with breast cancer and 250 presumably healthy controls. Risk of breast cancer associated with organochlorine concentration was evaluated. RESULTS:Mean levels of total DDT and HCB were significantly higher for breast cancer patients than for controls. No differences in serum levels of total DDT or HCB were found between oestrogen receptor positive and oestrogen receptor negative patients with breast cancer. CONCLUSIONS:These results add to the growing evidence that certain persistent pollutants may occur in higher concentrations in blood samples from breast cancer patients than controls.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Charlier C,Albert A,Herman P,Hamoir E,Gaspard U,Meurisse M,Plomteux Gdoi
10.1136/oem.60.5.348subject
Has Abstractpub_date
2003-05-01 00:00:00pages
348-51issue
5eissn
1351-0711issn
1470-7926journal_volume
60pub_type
杂志文章abstract:OBJECTIVES:To elucidate factors contributing to hard metal asthma, the entire workforce of a corporation producing hard metal tools (n = 703) was examined. METHODS:The variables evaluated were the atopy reflected by immunoglobulin E (IgE) antibody against mite allergen, history of exposure to hard metal, smoking, conc...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.3.188
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:To explore the psychological consequences of improvised explosive device (IED) exposure as IEDs have been the greatest threat to UK military personnel in Afghanistan though the mental health consequences of IED exposure are largely unknown. METHOD:Deployed UK military personnel completed a survey while deplo...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101903
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To investigate whether changes in objective working hour characteristics are associated with parallel changes in work-life conflict (WLC) among hospital employees. METHODS:Survey responses from three waves of the Finnish Public Sector study (2008, 2012 and 2015) were combined with payroll data from 91 days p...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104785
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:Occupational dust exposure has been associated with accelerated lung function decline, which in turn is associated with overall morbidity and mortality. In the current study, we assess potential benefits on lung function of hypothetical interventions that would reduce occupational exposure to fine particulate...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-105908
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:To examine the relation between exposure to acid anhydrides and the risk of developing immediate skin prick test responses to acid anhydride human serum albumin (AA-HSA) conjugates or work related respiratory symptoms; to assess whether these relations are modified by atopy or smoking. METHODS:A cohort of 5...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.10.684
更新日期:1998-10-01 00:00:00
abstract:AIMS:To evaluate an epidemiological approach to a national noise hazard surveillance strategy, and report current exposure levels in the Danish workplace. METHODS:A study base of 840 companies in 10 selected high risk industries in the largest county in Denmark was identified from a national register. Noise exposure w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.012757
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVES:Use of cost-benefit analysis in occupational health increases insight into the intervention strategy that maximises the cost-benefit ratio. This study presents a methodological framework identifying the most important elements of a cost-benefit analysis for occupational health settings. One of the main aims ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2011.064709
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:The main objective was to study the acute vascular effects in the hands of normal healthy subjects of a complex vibration spectrum similar to that generated by many industrial hand held tools. The effects of repeated bouts of vibrations and alterations in the intensity of vibration were also studied. METHOD...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.10.663
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVES:Studies in traditional paper mills have indicated an excess cancer risk, and mutagenic compounds have been identified in the industry. No studies have reported on risk of cancer in paper recycling. Therefore the cancer incidence in Danish paper recycling mills was investigated. METHODS:5377 employees in fiv...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.10.729
更新日期:1997-10-01 00:00:00
abstract:AIM:To compare two different methods for assessment of postural load and duration of computer use in office workers. METHODS:The study population existed of 87 computer workers. Questionnaire data about exposure were compared with exposures measured by a standardised or objective method. Measuring true exposure to pos...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.013219
更新日期:2004-12-01 00:00:00
abstract::Internationally, the debate on aims for occupational health policy is expanding its horizons. Included among the issues are not only concerns about safety for workers, but also for their progeny. Equality among the sexes is also assuming a prominent position. In several countries, existing and proposed legislation alr...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.52.5.294
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Assessment of exposure assessment to metal working fluids (MWF) has almost exclusively focused on inhalation exposure. AIMS:To assess levels of, and factors affecting, dermal and inhalation exposure to semi-synthetic MWF, and to identify suitable dermal exposure grouping schemes among metal workers for an e...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.015396
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVES:To investigate further whether inorganic lead is a carcinogen among adults, or associated with increased blood pressure and kidney damage, via a large mortality study. METHODS:We conducted internal analyses via Cox regression of mortality in three cohorts of lead-exposed workers with blood lead (BL) data (U...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104311
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Examine trends and patterns of work-related musculoskeletal disorders (WMSDs) among construction workers in the USA, with an emphasis on older workers. METHODS:WMSDs were identified from the 1992-2014 Survey of Occupational Injuries and Illnesses (SOII), and employment was estimated from the Current Populat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103943
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To investigate whether there is a relationship between fatigue and sickness absence. Two additional hypotheses were based on the theoretical distinction between involuntary, health related absence and voluntary, attitudinal absence. In the literature, the former term is usually used to describe long term sic...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.60.suppl_1.i71
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Few studies have investigated cancer risks in carbon black workers and the findings were inconclusive. METHODS:The current study explores the mortality of a cohort of 1535 male German blue-collar workers employed at a carbon black manufacturing plant for at least one year between 1960 and 1998. Vital status...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.026526
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:To determine whether results from questionnaires, exposure measurements, and laboratory tests, commonly used in occupational health practice, can predict the presence or absence of sensitisation in workers exposed to high molecular weight (HMW) allergens. The study aims to develop and validate a diagnostic r...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.3.189
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:Night shift work has been suggested as a possible risk factor for multiple sclerosis (MS). The objective of the present analysis was to prospectively evaluate the association of rotating night shift work history and MS risk in two female cohorts, the Nurses' Health Study (NHS) and NHSII. METHODS:A total of ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-106016
更新日期:2019-10-01 00:00:00
abstract:AIMS:To investigate work related and individual factors as predictors for incident neck pain among office employees working with video display units (VDUs). METHODS:Employees in three administrative units of a medium sized city in Finland (n = 515) received mailed questionnaires in the baseline survey in 1998 and in t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.7.475
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:An association has previously been reported between finger blanching and hearing difficulties, but only in workers with exposure to noise and hand transmitted vibration (HTV). AIMS:To explore the association in a community sample, including cases who lacked occupational exposure to noise or HTV. METHOD:A q...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.9.640
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVE:To investigate possible neurotoxic effects in groups of aluminium pot room and foundry workers, aluminium welders, and a small group of workers exposed to aluminium in the production of flake powder. METHODS:Exposure to aluminium was evaluated with aluminium concentrations in blood and urine as well as a que...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.7.453
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:To investigate the risk of cancer associated with exposure to air pollution among bus drivers and tramway employees. METHODS:A retrospective cohort study of 18,174 bus drivers or tramway employees in Copenhagen in the period 1900-94. Data on employment were obtained from company files. Information on cancer ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.9.594
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVES:To investigate changes in digital circulation during and after exposure to hand transmitted vibration. By studying two frequencies and two magnitudes of vibration, to investigate the extent to which haemodynamic changes depend on the vibration frequency, the vibration acceleration, and the vibration velocity...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.8.566
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVES:To assess sensitivity and specificity of a questionnaire designed to detect neurotoxic symptoms in workers exposed to solvents and in patients with a psycho-organic syndrome. METHODS:The Swedish Q16 is a self administered questionnaire for neurotoxic symptoms. The modified German version consists of 18 ques...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.58.1.19
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:To review and summarise the epidemiological evidence on the carcinogenicity of occupational exposure to inorganic lead. METHODS:Case-control and cohort studies were reviewed and combined for meta-analysis. Fixed and random effect methods were used to estimate the summary effects. RESULTS:The combined resul...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
doi:10.1136/oem.52.2.73
更新日期:1995-02-01 00:00:00
abstract::The hypothesis that asphalt workers are at increased risk of mortality from industrial accidents and other external causes was tested. Mortality rates for external and violent causes of death in a cohort of asphalt industry employees from seven European countries and Israel were compared to that of the general populat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:
更新日期:2004-01-01 00:00:00
abstract:AIMS:(1) To develop a transparent and broadly applicable method for assessing occupational safety and health (OSH) programmes or management systems; (2) to assess OSH programmes in a sample of manufacturing worksites; and (3) to determine whether a management focused occupational health intervention results in greater ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.011718
更新日期:2004-08-01 00:00:00
abstract::Male Wistar rats were exposed to two types of magnesium sulphate whiskers by inhalation for six hours a day, five days a week, for four weeks (sub-chronic study), or for one year (chronic study) to clarify the biological effects of the whiskers. There were few whiskers detected in the rat lungs even at one day after t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.7.492
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVES:Many residents in Beijing use disposable face masks in an attempt to protect their health from high particulate matter (PM) concentrations. Retail masks may be certified to local or international standards, but their real-life performance may not confer the exposure reduction potential that is marketed. This...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104765
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To estimate quantitative levels of exposure to diesel exhaust expressed by elemental carbon (EC) in the contemporary mining industry and to describe the excess risk of lung cancer that may result from those levels. METHODS:EC exposure has been monitored in Western Australian miners since 2003. Mixed-effects...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103808
更新日期:2017-03-01 00:00:00