Abstract:
OBJECTIVES:To evaluate whether hourly changes in fine particle (PM(2.5), diameter<2.5 microm) exposure or outdoor particle concentrations are associated with rapid ischaemic responses. METHODS:41 non-smoking elderly people with coronary heart disease were followed up with biweekly clinic visits in Helsinki, Finland. The occurrence of ST segment depressions >0.1 mV was recorded during submaximal exercise tests. Hourly variations in personal PM(2.5) exposure and outdoor levels of PM(2.5) and ultrafine particles (<0.1 microm) were recorded for 24 h before a clinic visit. Associations between particulate air pollution and ST segment depressions were evaluated using logistic regression. RESULTS:Both personal and outdoor PM(2.5) concentrations, but not outdoor ultrafine particle counts, were associated with ST segment depressions. The odds ratio (per 10 microg/m(3)) for personal PM(2.5) concentration during the hour preceding a clinic visit was 3.26 (95% CI 1.07 to 9.99) and for 4 h average outdoor PM(2.5) it was 2.47 (95% CI 1.05 to 5.85). CONCLUSIONS:Even very short-term elevations in fine particle exposure might increase the risk of myocardial ischaemia. The precise mechanism is still unknown but could involve changes in autonomic nervous control of the heart.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Lanki T,Hoek G,Timonen KL,Peters A,Tiittanen P,Vanninen E,Pekkanen Jdoi
10.1136/oem.2007.037531subject
Has Abstractpub_date
2008-11-01 00:00:00pages
782-6issue
11eissn
1351-0711issn
1470-7926pii
oem.2007.037531journal_volume
65pub_type
杂志文章abstract:OBJECTIVES:Vibration white finger (VWF), also known as "occupational Raynaud's phenomenon", is marked by arterial hyperresponsiveness and vasoconstriction during cold stimulation. The impact of tobacco use, and by extension stopping smoking, on the long term course of the disease has been inconclusively characterised. ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.5.341
更新日期:2000-05-01 00:00:00
abstract::The ability of amosite cored asbestos bodies isolated from human lungs to catalyse damage to phi X174 RFI DNA in vitro was measured and compared with that of uncoated amosite fibres with a similar distribution of length. Asbestos bodies (5000 bodies) suspended for 30 minutes in 50 mM NaCl containing 0.5 micrograms phi...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.3.200
更新日期:1994-03-01 00:00:00
abstract::Respiratory symptoms and ventilatory capacity were studied in a group of 288 workers (259 women and 29 men) employed in a confectionery plant. A group of workers (96 women and 31 men) not exposed to confectionery manufacture were also studied as controls. The prevalence of chronic respiratory symptoms was higher in ex...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.7.435
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVE:To estimate the fraction of carpal tunnel syndrome (CTS) that is attributable to work in the total adult population of the island of Montreal. METHODS:The population consisted of 1.1 million people 20-64 years of age, with 73.2% of men and 60.6% of women employed. The rates of first surgery for CTS were comp...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.7.519
更新日期:1997-07-01 00:00:00
abstract:OBJECTIVES:Assessment of level of exposure to platinum and platinum concentration in urine from platinum industry workers to evaluate internal exposures and excretion kinetics. METHODS:Platinum concentrations in urine samples from 34 workers were measured by adsorptive voltammetry after UV-photolysis. Morning and even...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.55.2.138
更新日期:1998-02-01 00:00:00
abstract:BACKGROUND:Natural rubber latex allergy can cause skin and respiratory symptoms The aim of this study was to evaluate the prevalence and incidence of latex related symptoms and sensitisation among a large group of healthcare workers in Trieste hospitals, followed for three years before and after the introduction of pow...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2003.011460
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVES:Ammonium perfluorooctanoate (APFO) is a biopersistent surfactant used in the manufacture of several types of fluoropolymers. Based on previous findings of increased serum lipid levels associated with exposure to APFO, we evaluated ischaemic heart disease (IHD) mortality in a cohort of occupationally exposed ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041582
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To assess whether CFS-like caseness (meeting the criteria for chronic fatigue syndrome (CFS)) predicts work status in the long term. METHODS:Prospective study in a sample of fatigued employees absent from work. Data were collected at baseline and four years later, and included CFS-like caseness and work stat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.023176
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Conclusions that can be drawn from earlier studies on noise and children's blood pressure are limited due to inconsistent results, methodological problems, and the focus on school noise exposure. OBJECTIVES:To investigate the effects of aircraft and road traffic noise exposure on children's blood pressure a...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.026831
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:Prevention of disability in the ageing workforce is essential for sustaining economic growth in Europe. In order to provide information on entry points for preventive measures, it is important to better understand sociodemographic, socioeconomic and work-related determinants of disability in older employees....
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2012-100924
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The erection of mobile telephone base stations in inhabited areas has raised concerns about possible health effects caused by emitted microwaves. METHODS:In a cross-sectional study of randomly selected inhabitants living in urban and rural areas for more than one year near to 10 selected base stations, 365 ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.020784
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of lumbar supports, education, and exercise in the prevention of back pain in industry. METHODS:A computerised search for controlled clinical trials was conducted. A criteria list was used to assess the methodological quality of the studies. The available evidence for the effectiv...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
doi:10.1136/oem.54.12.841
更新日期:1997-12-01 00:00:00
abstract:AIMS:To determine the cancer incidence in Swedish cabin crew. METHODS:Cancer incidence of cabin crew at the Swedish Scandinavian Airline System (SAS) (2324 women and 632 men) employed from 1957 to 1994 was determined during 1961-96 from the Swedish National Cancer Register. The cancer incidence in cabin crew was compa...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.11.810
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence and incidence of upper extremity musculoskeletal pain (UEMP) and related disability among office workers in Costa Rica, Nicaragua and Spain. METHODS:Data from the multinational Cultural and Psychosocial Influences on Disability (CUPID) study on 947 (93%) participants at baseline w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2015-103327
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:This paper describes findings from the study of chronic bronchitis (CB) incidence after occupational exposure to ionising radiation among workers employed at Russian Mayak Production Association (PA) during 1948 and 1982 and followed up until 2008 based on 'Mayak Worker Dosimetry System 2008'. METHODS:Analy...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2015-103283
更新日期:2017-02-01 00:00:00
abstract::The "need for recovery scale" is suggested as an operationalisation for the measurement of (early symptoms of) fatigue at work. Definition of and background on the concept of need for recovery are briefly discussed. Details about scale construction are summarised. Correlations with other relevant measurement scales on...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.suppl_1.i3
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To investigate allegations of an excess risk of leukaemia among children living near the Solway Firth coast of Dumfries and Galloway Health Board area in Scotland, UK. METHODS:Incident cases of childhood leukaemia (International Classification of Diseases, 10th revision, C91-C95, patients aged 0-14 years) fo...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.028829
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:To evaluate if occupational mechanical exposures are associated with an increased risk of surgery for varicose veins (VV) in the lower extremities. METHODS:We conducted a longitudinal study of persons from the Musculoskeletal Research Database at the Danish Ramazzini Centre who were 18-65 years old when the...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2014-102495
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:The aim was to assess the association between occupational biomechanical exposure and the occurrence of radial nerve entrapment (RNE) in construction workers over a 13-year follow-up period. METHODS:A cohort of 229 707 male construction workers who participated in a national occupational health surveillance...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2018-105311
更新日期:2019-05-01 00:00:00
abstract::Urinary N-acetyl-beta-D-glucosaminidase (NAG) had been shown to be a useful early marker of renal injury. In workers exposed to lead it seems to be the only early marker but the dose response and dose effect relations are weak. Furthermore, the significance and underlying mechanism of increased urinary NAG activity is...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.2.125
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVES:Night shift work has been classified as a probable human carcinogen by the International Agency for Research on Cancer, based on experimental studies and limited evidence on human breast cancer risk. Evidence at other cancer sites is scarce. We evaluated the association between night shift work and stomach c...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103597
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVES:Few studies have assessed the effects of policies aimed to reduce traffic-related air pollution. The aims of this study were to evaluate the impact, in terms of air quality and health effects, of two low-emission zones established in Rome in the period 2001-2005 and to assess the impact by socioeconomic posi...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2010.063750
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To investigate the differences between measurements of personal exposure to particulate air pollution and static area measurements in a group of people working close to traffic and to determine whether such differences might obscure any threshold for health effects in epidemiological studies. METHODS:Persona...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.12.790
更新日期:1995-12-01 00:00:00
abstract:BACKGROUND:Previous studies of the risk of heart disease after shift work reached different estimates and review authors disagree about the validity of some of the studies. A cross sectional study showed that shift workers had a higher prevalence of nearly every unfavourable work environment factor investigated. Confli...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2006.026716
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:The study investigated the utility of unmetabolised naphthalene (Nap) and phenanthrene (Phe) in urine as surrogates for exposures to mixtures of polycyclic aromatic hydrocarbons (PAHs). METHODS:The report included workers exposed to diesel exhausts (low PAH exposure level, n = 39) as well as those exposed t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041418
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Fetal growth restriction has been inconsistently associated with maternal exposure to elevated levels of traffic-related air pollution. OBJECTIVE:We investigated the relationship between an individualised measure of fetal growth and maternal exposure to a specific marker for traffic-related air pollution. ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100509
更新日期:2012-11-01 00:00:00
abstract:AIMS:To investigate the acute systemic inflammatory response to welding fume exposure. METHODS:Twenty four welders (42% smokers) and 13 non-exposed controls (23% smokers) were monitored at a welding school. Exposure to fine particulate matter (PM2.5) was assessed using cyclone samplers. Markers of systemic inflammatio...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.014795
更新日期:2005-03-01 00:00:00
abstract:AIMS:To test whether (1) physically demanding work is less frequent for older than younger employees, and whether (2) the association of physically demanding work with decline of physical functioning is stronger for older employees than their younger counterparts. The gender differences in these associations were exami...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.014035
更新日期:2005-02-01 00:00:00
abstract:AIMS:To assess the impact of newly introduced point-of-sale glass bottle recycling on indoor air quality and employee health. METHODS:Airborne exposures and both chronic and acute respiratory and somatic symptoms were surveyed among 226 employees at 36 randomly selected liquor stores with bottle recycling and in-house...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.009753
更新日期:2004-07-01 00:00:00
abstract::The International Agency for Research on Cancer has classified occupational exposure as a painter as 'carcinogenic to humans', largely based on increased risks of bladder and lung cancer. A meta-analysis, including more than 2900 incident cases or deaths from bladder cancer among painters reported in 41 cohort (n=2), ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.2009.051565
更新日期:2010-08-01 00:00:00