Abstract:
OBJECTIVES:Vibration white finger (VWF), also known as "occupational Raynaud's phenomenon", is marked by arterial hyperresponsiveness and vasoconstriction during cold stimulation. The impact of tobacco use, and by extension stopping smoking, on the long term course of the disease has been inconclusively characterised. The objectives of this study included assessment of the impact of tobacco use on symptoms and on objective tests in shipyard workers exposed to vibration, and in gauging the natural history of the disorder after stopping exposure and changing smoking patterns. METHODS:In a cross sectional investigation, 601 current and former users of pneumatic tools were evaluated subjectively for cold related vascular symptoms, and tested by cold challenge plethysmography. There was follow up and subsequent testing of 199 members of the severely effected subgroup of smokers and non-smokers, many of whom had stopped smoking in the interval between tests. Effects of smoking and stopping smoking on symptoms and plethsymographic results were assessed. RESULTS:Symptoms and measured abnormal vascular responses related to cold were more severe in smokers than in non-smokers. Follow up of 199 severely effected members of the cohort, all removed from exposure for 2 years, indicated that smokers were almost twice as likely to have more severe vasospasm (test finger/control finger systolic blood pressure% (FSBP%) <30) than were non-smokers (-32.2% v 17.4%). 53 Subjects who stopped smoking during the interval between tests improved, and were indistinguishable from non-smokers similarly exposed to vibration. Additional physiological benefits of stopping smoking were still apparent at further follow up examination, 1 year later. Improvements evident on plethysmography were not accompanied by improvements in symptoms, which were unaffected by smoking. CONCLUSIONS:Smoking seems to delay physiological improvement in response to cold challenge in workers with VWF, after the end of exposure to vibration. Symptoms were less likely to improve over time than digital blood pressure, and were less affected by smoking.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Cherniack M,Clive J,Seidner Adoi
10.1136/oem.57.5.341subject
Has Abstractpub_date
2000-05-01 00:00:00pages
341-7issue
5eissn
1351-0711issn
1470-7926journal_volume
57pub_type
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pub_type: 杂志文章
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更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:Depressive symptoms are associated with sickness absence, work disability and unemployment, but little is known about worklife expectancy (WLE). This study investigates the impact of depressive symptoms on the WLE of a large sample of Danish employees. METHODS:We used occupational health survey data of 11 96...
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journal_title:Occupational and environmental medicine
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.11.882
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journal_title:Occupational and environmental medicine
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abstract:BACKGROUND:Assessment of exposure assessment to metal working fluids (MWF) has almost exclusively focused on inhalation exposure. AIMS:To assess levels of, and factors affecting, dermal and inhalation exposure to semi-synthetic MWF, and to identify suitable dermal exposure grouping schemes among metal workers for an e...
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更新日期:2005-09-01 00:00:00
abstract:OBJECTIVES:(1) To investigate the association between temperature and work-related injuries and (2) to identify groups of workers at high risk of work-related injuries in hot environments in Adelaide, South Australia. METHODS:Workers' compensation claims in Adelaide, South Australia for 2001-2010 were used. The relati...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101584
更新日期:2014-04-01 00:00:00
abstract::Male Wistar rats were exposed to two types of magnesium sulphate whiskers by inhalation for six hours a day, five days a week, for four weeks (sub-chronic study), or for one year (chronic study) to clarify the biological effects of the whiskers. There were few whiskers detected in the rat lungs even at one day after t...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.7.492
更新日期:1994-07-01 00:00:00
abstract:OBJECTIVES:To describe the relation with age of risk of reported injury after a fall among women at work in two countries, the United Kingdom and Sweden, with particular emphasis on fractures, and to interpret these data. METHODS:Rates of accidents compiled under the national reporting regulations of each country duri...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.11.785
更新日期:1997-11-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.011718
更新日期:2004-08-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.009837
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:An association has previously been reported between finger blanching and hearing difficulties, but only in workers with exposure to noise and hand transmitted vibration (HTV). AIMS:To explore the association in a community sample, including cases who lacked occupational exposure to noise or HTV. METHOD:A q...
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doi:10.1136/oem.59.9.640
更新日期:2002-09-01 00:00:00
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doi:10.1136/oem.2003.009753
更新日期:2004-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
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更新日期:2000-11-01 00:00:00
abstract:OBJECTIVES:To evaluate work experiences among teens enrolled in school-sponsored work (SSW) programs and compare the findings to other-working teens. This study, the first to assess work-related safety and health for teens in SSW programs, includes teens working one job and teens working multiple jobs. METHODS:A surve...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2010.059170
更新日期:2011-11-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2015-103089
更新日期:2015-12-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2016-104168
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:We evaluated the association between exposure to polycyclic aromatic hydrocarbons (PAHs) and immunological measurements using blood samples from coke oven workers exposed to high and low PAH levels. METHODS:A population-based cross-sectional study was conducted from 2008-2009 with coke oven workers and stee...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2010.055020
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:The current definition of chronic obstructive pulmonary disease (COPD) associates persistent airflow limitation and chronic respiratory symptoms. Agricultural work has been associated with an increased risk of developing COPD, but the prevalence and definition of the disease vary greatly between studies. T...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
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更新日期:2019-01-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.017731
更新日期:2005-07-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.12.833
更新日期:1999-12-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.10.730
更新日期:2003-10-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.54.1.27
更新日期:1997-01-01 00:00:00
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journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2014-102160
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To investigate the occurrence of work related respiratory symptoms and to assess the effect of atopy in a group of trainee bakers. METHODS:A prospective study of work related respiratory symptoms among 125 trainee bakers who were investigated with a questionnaire plus skin prick test with wheat flour and al...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.1.58
更新日期:2000-01-01 00:00:00
abstract::Aerosol sampling has evolved with changes in technology and our understanding of the importance of assessing the biologically relevant fractions of the total aerosol. During the past decade there has been international agreement on the definitions for the inhalable, thoracic, and respirable fractions and instruments h...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.56.11.747
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVES:We used data from a large, population-based case-control study in Maine, New Hampshire, and Vermont to examine relationships between occupation, industry and bladder cancer risk. METHODS:Lifetime occupational histories were obtained by personal interview from 1158 patients newly diagnosed with urothelial ca...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,多中心研究
doi:10.1136/oem.2009.052571
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVES:To investigate the question of whether there is an association between workplace exposures and sociodemographic factors and mortality from non-malignant respiratory disease excluding influenza and pneumonia (NMRDxIP) among workers in a fibreglass wool manufacturing facility. METHODS:A case-control study wit...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.6.369
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence and incidence of upper extremity musculoskeletal pain (UEMP) and related disability among office workers in Costa Rica, Nicaragua and Spain. METHODS:Data from the multinational Cultural and Psychosocial Influences on Disability (CUPID) study on 947 (93%) participants at baseline w...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2015-103327
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To assess whether CFS-like caseness (meeting the criteria for chronic fatigue syndrome (CFS)) predicts work status in the long term. METHODS:Prospective study in a sample of fatigued employees absent from work. Data were collected at baseline and four years later, and included CFS-like caseness and work stat...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2005.023176
更新日期:2006-08-01 00:00:00