Plantibodies: applications, advantages and bottlenecks.

Abstract:

:Various strategies have been developed to exploit plants as bioreactors for the production of pharmaceutical antibodies, to engineer antibody-mediated pathogen resistance or to alter the plant phenotype by immunomodulation. Recent research developments focus on the fine-tuning of expression systems and the detailed characterisation of recombinant products, including the implications of plant-specific glycosylation. Meanwhile, the first of these plant-derived antibody products has successfully completed early phase clinical trials.

journal_name

Curr Opin Biotechnol

authors

Stoger E,Sack M,Fischer R,Christou P

doi

10.1016/s0958-1669(02)00303-8

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

161-6

issue

2

eissn

0958-1669

issn

1879-0429

pii

S0958166902003038

journal_volume

13

pub_type

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