Abstract:
:The cellular distribution of PP and PYY in mammals is reviewed. Expression of PP is restricted to endocrine cells mainly present in the pancreas predominantly in the duodenal portion (head) but also found in small numbers in the gastro-intestinal tract. PYY has a dual expression in both endocrine cells and neurons. PYY expressing endocrine cells occur all along the gastrointestinal tract and are frequent in the distal portion. Islet cells expressing PYY are found in many species. In rodents they predominate in the splenic portion (tail) of the pancreas. A limited expression of PYY is found also in endocrine cells in the adrenal gland, respiratory tract and pituitary. Peripheral, particularly enteric, neurons also express PYY as does a restricted set of central neurons.
journal_name
Peptidesjournal_title
Peptidesauthors
Ekblad E,Sundler Fdoi
10.1016/s0196-9781(01)00601-5subject
Has Abstractpub_date
2002-02-01 00:00:00pages
251-61issue
2eissn
0196-9781issn
1873-5169pii
S0196978101006015journal_volume
23pub_type
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