Serial magnetic resonance imaging of global and regional left ventricular remodeling during 1 year after acute myocardial infarction.

Abstract:

:Biplane long-axis cine MRI was performed in 51 patients 1, 13, 26, and 52 weeks after their first AMI. LV mass index (LVMI) was significantly increased 1 week after AMI (84.3 +/- 16.9 vs. 68.1 +/- 11.4 g/m(2) controls, n = 48, p < 0.001), presumably owing to edema of the infarcted myocardium. Six months after AMI, LVMI decreased to 76.5 +/- 16.4 g/m(2), but had again augmented after 1 year (81.8 +/- 17.3 g/m(2), p < 0.05), suggesting late, compensatory left ventricular hypertrophy. In patients treated with primary percutaneous transluminal coronary angioplasty, LVMI decreased 5% over 1 year, while LVMI increased 10% in patients receiving thrombolysis (p < 0.05). In the entire population, the global increase in LVMI 1 year after AMI seemed to reflect global cavity dilatation with unchanged thickness of the vital myocardium. In conclusion, in patients receiving contemporary treatment, LV remodeling only partially complied with the classical patho-anatomical concept.

journal_name

Cardiology

journal_title

Cardiology

authors

Schroeder AP,Houlind K,Pedersen EM,Nielsen TT,Egeblad H

doi

10.1159/000049092

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

106-14

issue

2

eissn

0008-6312

issn

1421-9751

pii

crd96106

journal_volume

96

pub_type

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