Abstract:
:A previous study in rabbit hearts demonstrated the feasibility of creating transmyocardial channels by application of temperature-regulated high-frequency (HF) energy. Feasibility of creating non-transmural channels using a transvascular approach was tested in 14 pigs which were followed for 1 h, and 3 and 9 weeks (group A, B and C). Myocardial channels were found to be highly reproducible and patent in more than two thirds in group A. Channels were replaced by connective tissue during follow-up which contained newly formed small vessels. A functional communication between the left ventricular cavum and newly formed vessels of the channel remnants could be demonstrated in one heart of group C. Thus, intramyocardial HF ablation can be performed with high reproducibility to induce local angiogenesis.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Dietz U,Horstick G,Manke T,Otto M,Eick O,Kirkpatrick CJ,Meyer J,Darius Hdoi
10.1159/000068450subject
Has Abstractpub_date
2003-01-01 00:00:00pages
32-8issue
1eissn
0008-6312issn
1421-9751pii
68450journal_volume
99pub_type
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