Abstract:
:This study shows significant changes occurring in systolic time intervals in an experimental animal model of aortic outflow obstruction with cardiac hypertrophy. The left ventricular ejection time is markedly prolonged and the preejection period/left ventricular ejection time ratio shortened. These changes are in the opposite direction of those usually observed with left ventricular dysfunction in man but similar to those described in man with aortic stenosis. Furthermore, the changes observed in systolic time intervals after digoxin in this experimental model are not comparable to those reported in man with normal or abnormal left ventricular function. Hence, the use of systolic time intervals, including digitalis effect, to evaluate the functional state of the left ventricle in aortic outflow obstruction are probably unreliable.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Murphy ML,Doherty JE,de Soyza N,Kane JJ,Straub KDdoi
10.1159/000173260subject
Has Abstractpub_date
1981-01-01 00:00:00pages
19-29issue
1eissn
0008-6312issn
1421-9751journal_volume
68pub_type
杂志文章相关文献
CARDIOLOGY文献大全abstract::A previous study in rabbit hearts demonstrated the feasibility of creating transmyocardial channels by application of temperature-regulated high-frequency (HF) energy. Feasibility of creating non-transmural channels using a transvascular approach was tested in 14 pigs which were followed for 1 h, and 3 and 9 weeks (gr...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000068450
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:A significant number of heart failure (HF) patients with reduced left ventricular ejection fraction (LVEF) experience ventricular function recovery during follow-up. We studied the variables associated with LVEF recovery in patients treated with sacubitril/valsartan (SV) in clinical practice. METHODS:We ana...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000505148
更新日期:2020-01-01 00:00:00
abstract::To determine the success rate and the safety of percutaneous transluminal coronary angioplasty in patients with unstable angina pectoris (group 1) versus stable angina (group 2), we studied 299 consecutive patients who underwent coronary angioplasty of 373 consecutive lesions. Of these patients, 149 had unstable angin...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175811
更新日期:1992-01-01 00:00:00
abstract::In a 79-year-old female with shortness of breath, catheterization via the femoral vein encountered difficulty entering the right heart; venography revealed anomalous drainage of the inferior vena cava via a dilated azygos vein permitting subsequent catheterization. Similar difficulties during catheterization merit con...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176884
更新日期:1995-01-01 00:00:00
abstract::Thromboembolism is a major complication of long-term central venous catheter, usually associated with catheter or venous occlusion. Intracavitary right atrial thrombosis is currently considered to result from line-tip thrombosis extension. We report three adult patients in whom repeated mechanical trauma to the right ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006905
更新日期:1999-01-01 00:00:00
abstract::Cell membrane phospholipids, including platelet-activating factor (PAF), participate in the pathogenesis of acute myocardial infarction (AMI). The plasma level of PAF acetylhydrolase (AH) was determined in 18 patients at presentation with AMI before thrombolysis, and the administration of adjunctive therapy, and compa...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000006831
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:Transforming growth factor β1 (TGF-β1) is the major cytokine for stimulating endothelial cells (ECs) to transdifferentiate to mesenchymal cells (MCs) in the process known as endothelial-to-mesenchymal transition (EndMT). Recently, TGF-β1-induced EndMT has been implicated in the pathogenesis of atherosclerosis...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000464321
更新日期:2017-01-01 00:00:00
abstract::Helicobacter pylori infects over 50% of the worldwide population. For eradication, European, Canadian, and American guidelines recommend a regimen consisting of a proton pump inhibitor, clarithromycin, and metronidazole or amoxicillin dosed twice daily for at least 7 days. When this treatment strategy fails, a complex...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000110489
更新日期:2008-01-01 00:00:00
abstract::Previous studies have compared the outcome between patients with and without a confirmed acute myocardial infarction (AMI) mainly during the first few years after its onset. Our aim was to compare the prognosis between patients with and without a confirmed AMI during 10 years of follow-up. Patients participating in an...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000176529
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND/AIMS:Mitral regurgitation (MR) is frequently observed in patients with acute myocardial infarction (AMI), and is known to convey an adverse prognosis. We sought to clarify the relationship between MR and left ventricular (LV) remodeling, in association with serum C-reactive protein (CRP) elevation. METHODS/...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000099057
更新日期:2007-01-01 00:00:00
abstract::Transcatheter electrical shock ablation of a concealed posteroseptal accessory pathway was performed on a 57-year-old man with drug-refractory paroxysmal supraventricular tachycardia. A single 300-joules shock delivered at the ostium of the coronary sinus abolished conduction in the accessory pathway and resulted in l...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000174387
更新日期:1988-01-01 00:00:00
abstract::The blood pressure behavior during and after ergometric exercise was investigated in 552 males in order to clarify if this standardized procedure is suitable for differentiating between normotensive subjects and hypertensive patients. Patients suffering from mild hypertension showed significantly (p less than 0.001) h...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000173856
更新日期:1985-01-01 00:00:00
abstract::Protruding aortic plaques--especially those with mobile properties--on transesophageal echocardiography (TEE) are a potential source of stroke and systemic embolism in the elderly. Whether the various morphologies of atheromas with mobile components represent potential differences in the risk for embolic events has no...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006795
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:To investigate the mechanism of alpha-allocryptopine-induced inhibition of the transient outward potassium current (I(to)) in rabbit left-ventricular myocytes. METHODS:We used the whole-cell patch-clamp technique to record the I(to) in the myocytes, which were isolated from the rabbit left ventricle by a Lan...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000127443
更新日期:2008-01-01 00:00:00
abstract::The acute effects of therapeutic doses of intravenous tolbutamide and glibornuride on the systolic time intervals (QS2c, LVETc, PEPc and PEP/LVET) were examined in 5 healthy volunteers. Blood sugar was maintained constant throughout the study. No significant changes of these intervals as well as of heart rate and bloo...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000170617
更新日期:1979-01-01 00:00:00
abstract::A double-chambered right ventricle (DCRV) is an uncommon congenital anomaly: the right ventricle (RV) is divided into two chambers due to the presence of an abnormally located muscular band or anomalous muscle hypertrophy in the subinfundibular part of RV outflow tract, with a variable degree of obstruction. Generally...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000444743
更新日期:2016-01-01 00:00:00
abstract:CONTEXT:Oral reversible platelet P2Y12 receptor inhibitors (ticagrelor and elinogrel) cause double-digit rates of dyspnea, while irreversible oral antiplatelet drugs (aspirin, ticlopidoine, clopidogrel, and prasugrel) or intravenous glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, or tirofiban) do not increas...
journal_title:Cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000354876
更新日期:2014-01-01 00:00:00
abstract::Fifteen congestive heart failure patients (NYHA: class III or IV) were enrolled in the study and were classified into two groups. Six patients (group I) received combined therapy by nitroglycerin tape (5 mg) and ibopamine (100 mg), while the remaining 9 patients (group II) were given nitroglycerin tape (5 mg) and nife...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000174696
更新日期:1990-01-01 00:00:00
abstract::Three generations of a family with the Romano-Ward syndrome are described. Of all the affected members, only 1 was symptomatic, experiencing episodes of syncope proven to be due to polymorphous ventricular tachycardia (PMVT) induced by chlorimipramine treatment for depression. During treatment of an episode of PMVT wi...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173500
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To assess whether postoperative quality of life (QOL) for composite aortic root replacement patients differs according to whether it is based on the use of mechanical valves or bioprosthetic valves. METHODS:The study included 146 consecutive patients who underwent composite aortic root replacement at our ins...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000438783
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The objective was to evaluate the effect of hormone replacement therapy (HRT) on plasma homocysteine levels in postmenopausal women with coronary artery disease (CAD) and to investigate associations of homocysteine to other cardiovascular risk factors. METHODS:The women in this single-center, controlled, and...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000064667
更新日期:2002-01-01 00:00:00
abstract::During a 21-month period, the prognosis in all patients admitted to a hospital ward from the emergency room with suspected acute myocardial infarction (AMI) was prospectively recorded and related to the time between onset of symptoms and arrival in hospital. They were classified as early arrivers (less than or equal t...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000174777
更新日期:1991-01-01 00:00:00
abstract::Hybrid coronary revascularization (HCR) combines surgical bypass with percutaneous coronary intervention (PCI) performed either during the same procedure or in a staged approach within 60 days. Coronary artery bypass grafting using the left internal mammary artery (LIMA) has shown excellent long-term patency with impr...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000488190
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:The present study aimed to evaluate the hypertension status of community residents, analyze environmental and epigenetic factors, and propose prevention measures for hypertension. METHODS:In our study, different methylation levels were distinguished utilizing melting temperature (Tm) values in both the case...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000458520
更新日期:2017-01-01 00:00:00
abstract::The EKG response to exercise and the working capacity in a group of 70 patients with positive serology for Chagas' disease has been determined by stress testing on a bicycle-ergometer, in order to establish the usefulness of such a test in the early diagnosis of Chagas' cardiomyopathy. The exercise EKG provides inform...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000169915
更新日期:1978-01-01 00:00:00
abstract::Carvedilol is a multiple-action cardiovascular agent that is a nonselective beta-adrenoceptor antagonist and a vasodilator. beta-Adrenoceptor antagonists reduce myocardial work, secondary to reductions in heart rate and contractility, both in animals and in humans. For these reasons, carvedilol may improve survival of...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175930
更新日期:1993-01-01 00:00:00
abstract::(1) 36 outpatients with a manifest orthostatic syndrome were the subject of a double-blind study to investigate the influence of Dihydergot and a placebo over a 4-week period. (2) In the majority of subjects, the dosage was 1 tablet (2.5 mg) 3 times a day. (3) In the test group with Dihydergot (17 subjects), a normali...
journal_title:Cardiology
pub_type: 临床试验,杂志文章
doi:10.1159/000169827
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is largely unknown. Proteomics offers an approach to overview the molecular activities and signal transduction pathways involved in specific disease processes. OBJECTIVES:In this study, the expression of proteins in endarterectomized ...
journal_title:Cardiology
pub_type: 新闻
doi:10.1159/000502831
更新日期:2020-01-01 00:00:00
abstract::The prognostic information from 24-hour monitoring with on-line vectorcardiography (VCG) was assessed in 100 patients with a clinical diagnosis of unstable angina pectoris. ST change vector magnitude, ST vector magnitude and QRS vector difference were monitored. During a follow-up period of 343 +/- 77 days, 7 patients...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176832
更新日期:1995-01-01 00:00:00
abstract::Abnormal atrial depolarization, characterized by P waves >or=110 ms on the electrocardiogram, can manifest as partial or advanced interatrial conduction delay or interatrial block (IAB). Progression from partial to advanced IAB has been shown to be altered by the use of angiotensin-converting enzyme inhibitors and bet...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000113425
更新日期:2008-01-01 00:00:00