Risk factors for frequent and severe hypoglycemia in type 1 diabetes.

abstract：OBJECTIVE:Insulin pump therapy (continuous subcutaneous insulin infusion [CSII]) and multiple daily injections (MDIs) with insulin glargine as basal insulin and mealtime insulin lispro have not been prospectively compared in people naïve to either regimen in a multicenter study. We aimed to help close that deficiency. ...

journal_title：Diabetes care

authors： Bolli GB,Kerr D,Thomas R,Torlone E,Sola-Gazagnes A,Vitacolonna E,Selam JL,Home PD

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:Diabetes is a major predictor of death from heart disease and stroke; its impact on nonvascular mortality, including specific cancers, is less understood. We examined the association of diabetes with cause-specific mortality, including deaths from specific cancers. RESEARCH DESIGN AND METHODS:A prospective c...

journal_title：Diabetes care

authors： Campbell PT,Newton CC,Patel AV,Jacobs EJ,Gapstur SM

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To explore the hypothesis that a relationship exists between free radical activity and abnormalities in hemostasis in NIDDM. RESEARCH DESIGN AND METHODS:The use of the total radical-trapping antioxidant parameter (TRAP) has very recently been proposed to explore the antioxidant property of a plasma and their...

journal_title：Diabetes care

authors： Ceriello A,Bortolotti N,Pirisi M,Crescentini A,Tonutti L,Motz E,Russo A,Giacomello R,Stel G,Taboga C

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:To compare diabetes care and outcomes among Haitians, African Americans, and non-Hispanic whites. RESEARCH DESIGN AND METHODS:We analyzed data from 715 Haitian, 1,472 African American, and 466 non-Hispanic white adults with diabetes using χ² testing and multiple logistic regression. RESULTS:Haitians had a h...

journal_title：Diabetes care

authors： Vimalananda VG,Rosenzweig JL,Cabral HJ,David MM,Lasser KE

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To determine whether clinically significant differences exist in fasting blood glucose (BG) at the forearm, palm, and thigh relative to the fingertip; to assess the impact of prandial status by comparing BG between alternative sites and the fingertip at several time intervals after carbohydrate intake; to ass...

journal_title：Diabetes care

authors： Bina DM,Anderson RL,Johnson ML,Bergenstal RM,Kendall DM

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of clinically obtainable improvements in metabolic control in patients with type 1 diabetes on biochemical cardiovascular risk factors. RESEARCH DESIGN AND METHODS:Blood and 24-h urinary samples were obtained from 49 patients with type 1 diabetes before and after a run-in period and af...

journal_title：Diabetes care

authors： Djurhuus MS,Henriksen JE,Klitgaard NA,Blaabjerg O,Thye-Rønn P,Altura BM,Altura BT,Beck-Nielsen H

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To study the relationship between the prevalence of impaired glucose tolerance (IGT) and non-insulin-dependent diabetes mellitus (NIDDM) across populations of the Pacific Ocean region to assess whether variability in those two proportions followed some predictable pattern related to modernization of life-styl...

journal_title：Diabetes care

authors： Dowse GK,Zimmet PZ,King H

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:This study describes changes in the distribution of cigarette smoking and in physicians' advice to quit smoking among the U.S. population with and without diabetes from the mid-1970s to 1990. RESEARCH DESIGN AND METHODS:Data on self-reported smoking status, physicians' advice to quit smoking, history of diab...

journal_title：Diabetes care

authors： Malarcher AM,Ford ES,Nelson DE,Chrismon JH,Mowery P,Merritt RK,Herman WH

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:Peripheral neuropathy is the most frequent neurological complication in diabetic patients. The diagnosis is established by both clinical neurological examination and demonstration of reduced epidermal nerve fibers in skin biopsies (1). Whereas the decrease of free nerve endings has been extensively studied in...

journal_title：Diabetes care

authors： Reinisch CM,Traxler H,Piringer S,Tangl S,Nader A,Tschachler E

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:Emerging evidence suggests that peripheral neuropathy begins in the early stages of diabetes pathogenesis. Our objective was to describe the prevalence of peripheral neuropathy and nerve dysfunction according to glucose tolerance and metabolic syndrome status and examine how these conditions are associated wi...

journal_title：Diabetes care

authors： Lee CC,Perkins BA,Kayaniyil S,Harris SB,Retnakaran R,Gerstein HC,Zinman B,Hanley AJ

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Progressive nephropathy represents a substantial source of morbidity and mortality in type 1 diabetes. Increasing albuminuria is a strong predictor of progressive renal dysfunction and heightened cardiovascular risk. Early albuminuria probably reflects vascular endothelial dysfunction, which may be mediated i...

journal_title：Diabetes care

authors： Lin J,Glynn RJ,Rifai N,Manson JE,Ridker PM,Nathan DM,Schaumberg DA

更新日期：2008-12-01 00:00:00

abstract：:A preliminary study was performed to estimate the effect of biosynthetic human insulin (BHI) produced by the Eli Lilly Company in comparison with purified pork insulin (PPI) from the same manufacturer. Immunologic studies were done using an intradermal skin test with both insulins and in vitro studies binding with ser...

journal_title：Diabetes care

authors： Federlin K,Laube H,Velcovsky HG

更新日期：1981-03-01 00:00:00

abstract：OBJECTIVE:To determine whether the severity of retinopathy is higher in a group of NIDDM patients with sBP greater than or equal to 140 mmHg compared with NIDDM patients with sBP less than 140 mmHg. RESEARCH DESIGN AND METHODS:Ophthalmoscopy and FAG were conducted among a group of NIDDM patients with either a sBP abov...

journal_title：Diabetes care

authors： Cignarelli M,De Cicco ML,Damato A,Paternostro A,Pagliarini S,Santoro S,Cardia L,De Pergola G,Giorgino R

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVE:To test the utility of homeostasis model assessment (HOMA) in predicting insulin sensitivity [x10(- 4) min(-1)/(microIU/ml)] in children and to develop and compare two new prediction equations for insulin sensitivity in children using demographic and anthropometric measures in the presence or absence of fasti...

journal_title：Diabetes care

authors： Huang TT,Johnson MS,Goran MI

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:The objective was to examine prospectively the association between low testosterone and sex hormone-binding globulin (SHBG) levels and the subsequent development of type 2 diabetes in men. RESEARCH DESIGN AND METHODS:Analyses were conducted on the cohort of the Massachusetts Male Aging Study, a population-ba...

journal_title：Diabetes care

authors： Stellato RK,Feldman HA,Hamdy O,Horton ES,McKinlay JB

更新日期：2000-04-01 00:00:00

abstract：:OBJECTIVE The American Diabetes Association advocates insulin regimens for youth with type 1 diabetes that involve adjusting insulin dose based on carbohydrate intake and blood glucose level. Implementing these regimens requires knowledge about carbohydrate content of foods and subsequent calculations of insulin dose,...

journal_title：Diabetes care

authors： Koontz MB,Cuttler L,Palmert MR,O'Riordan M,Borawski EA,McConnell J,Kern EO

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVE:To determine the usefulness of measuring hemoglobin A(1c) (A1C), alone or combined with the fasting glucose test, compared with the oral glucose tolerance test (OGTT) for the reassessment of the carbohydrate metabolism status in postpartum women with a history of gestational diabetes mellitus (GDM). RESEARCH...

journal_title：Diabetes care

authors： Picón MJ,Murri M,Muñoz A,Fernández-García JC,Gomez-Huelgas R,Tinahones FJ

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:To investigate whether the risk for autoimmune diabetes in adults differs between socioeconomic groups and to compare such risk with that for type 2 diabetes. RESEARCH DESIGN AND METHODS:The inhabitants of the Norwegian county of Nord-Trøndelag were investigated by questionnaires and clinical examinations on...

journal_title：Diabetes care

authors： Olsson L,Ahlbom A,Grill V,Midthjell K,Carlsson S

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To determine whether, after adjustment for glycemia and other selected covariates, hemoglobin A1c (HbA1c) differed among adults from six Hispanic/Latino heritage groups (Central American, Cuban, Dominican, Mexican, Puerto Rican, and South American) and between Hispanic/Latino and non-Hispanic white adults wit...

journal_title：Diabetes care

authors： Avilés-Santa ML,Hsu LL,Arredondo M,Menke A,Werner E,Thyagarajan B,Heiss G,Teng Y,Schneiderman N,Giachello AL,Gallo LC,Talavera GA,Cowie CC

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Determine the efficacy of a home-based walking intervention to improve walking ability and quality of life in people with diabetes and peripheral arterial disease (PAD). RESEARCH DESIGN AND METHODS:We conducted a randomized, controlled, single-blind trial within university-affiliated clinics in our local com...

journal_title：Diabetes care

authors： Collins TC,Lunos S,Carlson T,Henderson K,Lightbourne M,Nelson B,Hodges JS

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that hyperinsulinemia among relatives of NIDDM probands will increase the prevalence of DLPs, we measured insulin levels and examined the frequency of DLPs among NIDDM pedigree members. RESEARCH DESIGN AND METHODS:We performed 2-h 75-g OGTTs and measured lipid and insulin levels of ...

journal_title：Diabetes care

authors： Schumacher MC,Maxwell TM,Wu LL,Hunt SC,Williams RR,Elbein SC

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:An artificial pancreas (AP) that automatically regulates blood glucose would greatly improve the lives of individuals with diabetes. Such a device would prevent hypo- and hyperglycemia along with associated long- and short-term complications as well as ease some of the day-to-day burden of frequent blood gluc...

journal_title：Diabetes care

authors： Dassau E,Zisser H,Harvey RA,Percival MW,Grosman B,Bevier W,Atlas E,Miller S,Nimri R,Jovanovic L,Doyle FJ 3rd

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Long-term exposure to alcohol is associated with an improvement in insulin sensitivity. At this time, however, there is no definitive proof that alcohol per se has an effect on the insulin sensitivity index (S(i)) in type 2 diabetes patients. The aim of the present study was to assess the role of acute modera...

journal_title：Diabetes care

authors： Avogaro A,Watanabe RM,Dall'Arche A,De Kreutzenberg SV,Tiengo A,Pacini G

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:To determine the effect of treatment with insulin aspart compared with NPH insulin, together with metformin/placebo and rosiglitazone/placebo. The hypothesis was that combined correction of major pathogenetic defects in type 2 diabetes would result in optimal glycemic control. RESEARCH DESIGN AND METHODS:Thi...

journal_title：Diabetes care

authors： Gram J,Henriksen JE,Grodum E,Juhl H,Hansen TB,Christiansen C,Yderstræde K,Gjessing H,Hansen HM,Vestergaard V,Hangaard J,Beck-Nielsen H

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To identify hormonal, psychological, and demographic predictors of symptom detection and accuracy of blood glucose estimation during mild hypoglycemia in adolescents and young adults with type 1 diabetes. RESEARCH DESIGN AND METHODS:During an insulin-glucose clamp study, 53 adolescents and 19 young adults es...

journal_title：Diabetes care

authors： Ryan CM,Dulay D,Suprasongsin C,Becker DJ

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To determine the association between serum 25-hydroxyvitamin D (25OHD) and diabetes risk and whether it varies by ethnicity. RESEARCH DESIGN AND METHODS:We performed an analysis of data from participants who attended the morning examination of the Third National Health and Nutrition Examination Survey (1988-...

journal_title：Diabetes care

authors： Scragg R,Sowers M,Bell C,Third National Health and Nutrition Examination Survey.

更新日期：2004-12-01 00:00:00

abstract：:OBJECTIVE Pharmacological profiles of biphasic insulin aspart 30/70 (BIAsp 30) once daily (OD), twice daily (b.i.d.), and three times daily (t.i.d.) were compared with other insulin regimens in two crossover glucose clamp studies of insulin-treated type 2 diabetic patients. RESEARCH DESIGNS AND METHODS Study 1 consist...

journal_title：Diabetes care

authors： Heise T,Heinemann L,Hövelmann U,Brauns B,Nosek L,Haahr HL,Olsen KJ

更新日期：2009-08-01 00:00:00

abstract：:Patients with diabetes mellitus may have any one of several forms of hypertension. These include essential hypertension, systolic hypertension of three varieties, the hypertension associated with diabetic nephropathy ("diabetic hypertension"), and the hypertension associated with neuropathy (supine hypertension with o...

journal_title：Diabetes care

authors： Christlieb AR

更新日期：1982-01-01 00:00:00

abstract：:OBJECTIVE--To determine the prevalence of non-insulin-dependent diabetes mellitus (NIDDM), impaired glucose tolerance (IGT), and hypertension in a rural community of Bangladesh. RESEARCH DESIGN AND METHODS--A cluster sampling of 1,005 subjects > 15 years of age in the rural community of Dohar was investigated. Capilla...

journal_title：Diabetes care

authors： Abu Sayeed M,Banu A,Khan AR,Hussain MZ

更新日期：1995-04-01 00:00:00

abstract：:Many of the family psychosocial variables significantly related to child abuse are also significantly related to insulin-dependent diabetes mellitus (IDDM) control. These variables are reviewed, and an increased child abuse risk factor for children with IDDM is discussed. Behavioral indicators of families experiencing...

journal_title：Diabetes care

authors： Horan PF,Gwynn C,Renzi D

更新日期：1986-05-01 00:00:00