Hypertension and chronotherapy: shifting the treatment paradigm.

abstract：BACKGROUND:The aim of our study was to investigate the control of hypertension (HT) in treated children using ambulatory blood pressure (BP) monitoring (ABPM). METHODS:We retrospectively reviewed all ABPM studies in our center. Controlled HT was defined as systolic and diastolic BP index (patients' BP divided by the 9...

journal_title：American journal of hypertension

authors： Seeman T,Dostálek L,Gilík J

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:We compared the cost-effectiveness of hypertension treatment in non-Hispanic blacks and non-Hispanic whites according to 2014 US hypertension treatment guidelines. METHODS:The cardiovascular disease (CVD) policy model simulated CVD events, quality-adjusted life years (QALYs), and treatment costs in 35- to 7...

journal_title：American journal of hypertension

authors： Vasudeva E,Moise N,Huang C,Mason A,Penko J,Goldman L,Coxson PG,Bibbins-Domingo K,Moran AE

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Marinobufagenin (MBG) is an endogenous Na/K-ATPase inhibitor, a natriuretic and a vasoconstrictor. MBG is implicated in salt-sensitive hypertension, cardiac hypertrophy, and initiate the pro-fibrotic signaling. Previously it was demonstrated that immunoneutralization of an endogenous MBG by 3E9 anti-MBG-anti...

journal_title：American journal of hypertension

authors： Grigorova YN,Juhasz O,Zernetkina V,Fishbein KW,Lakatta EG,Fedorova OV,Bagrov AY

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Altered diastolic filling is an important contributor to several cardiovascular disorders. Multiple lines of evidence suggest a genetic contribution to left ventricular (LV) diastolic filling; however, chromosomal locations harboring genes involved in impaired LV diastolic filling have not been reported. The...

journal_title：American journal of hypertension

authors： Tang W,Arnett DK,Devereux RB,Atwood LD,Kitzman DW,Rao DC

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Considering sex differences, salt sensitivity, and insulin resistance (IR), the effect of sodium restriction and increased potassium intake on blood pressure remains unclear in normotensive Asian individuals, compared to that in hypertensive patients. METHODS:To assess the influence of sodium and potassium ...

journal_title：American journal of hypertension

authors： Murao S,Takata Y,Yasuda M,Osawa H,Kohi F

更新日期：2018-07-16 00:00:00

abstract：BACKGROUND:Prenatal lipopolysaccharide (LPS) exposure causes hypertension in rat offspring through an unknown mechanism. Here, we investigated the role of the intrarenal renin-angiotensin system (RAS) in hypertension induced by prenatal LPS exposure and also explored whether adipose tissue-derived mesenchymal stem cell...

journal_title：American journal of hypertension

authors： Ding XF,Sun M,Guan FX,Guo LN,Zhang YY,Wan YD,Zhang XJ,Yu YW,Ma SS,Yao HM,Yao R,Zhang RF,Sun TW,Kan QC

更新日期：2017-11-06 00:00:00

abstract：:We studied the role of the sympathetic nervous system and the renin angiotensin system for pressure induced left ventricular hypertrophy (LVH) in 135 rats with experimental supravalvular aortic stenosis (AS). We induced this condition by a silver clip on the ascending aorta, when body weight (BW) was 90 to 100 g. Symp...

journal_title：American journal of hypertension

authors： Kromer EP,Elsner D,Riegger GA

更新日期：1991-06-01 00:00:00

abstract：:Cardiovascular diseases (CVD) are the major causes of mortality in persons with diabetes, and many factors, including hypertension, contribute to this high prevalence of CVD. The incidence of hypertension in patients with diabetes is approximately twofold higher than in age-matched subjects without the disease, and co...

journal_title：American journal of hypertension

authors： Sowers JR

更新日期：2003-11-01 00:00:00

abstract：:To assess whether aerobic exercise training is an effective and an alternative method to control blood pressure (BP) in hypertension, 32 uncomplicated, never treated patients suffering from mild-to-moderate essential arterial hypertension (EAH) were included in an aerobic exercise training program using a regular stan...

journal_title：American journal of hypertension

authors： Nami R,Mondillo S,Agricola E,Lenti S,Ferro G,Nami N,Tarantino M,Glauco G,Spanò E,Gennari C

更新日期：2000-06-01 00:00:00

abstract：:Preeclampsia is a pregnancy-induced hypertensive disorder characterized by proteinuria and widespread maternal endothelial dysfunction. It remains one of the most common disorders in pregnancy and remains one of the leading causes of maternal and fetal morbidity. Recent research has revealed that placental insufficien...

journal_title：American journal of hypertension

authors： George EM,Granger JP

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:High blood pressure (BP) is associated with the presence and severity of subclinical disease. Less is known about associations between normal levels of BP and various measures of subclinical disease. METHODS:The Multi-Ethnic Study of Atherosclerosis (MESA) enrolled 6814 participants free of clinical cardiov...

journal_title：American journal of hypertension

authors： Psaty BM,Arnold AM,Olson J,Saad MF,Shea S,Post W,Burke GL

更新日期：2006-11-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs interfere with certain antihypertensive therapies. In a double-blind study, 385 hypertensive patients stabilized on an angiotensin converting enzyme inhibitor were treated with nabumetone, celecoxib, ibuprofen, or placebo for 4 weeks. Ibuprofen caused significantly greater increase...

journal_title：American journal of hypertension

authors： Palmer R,Weiss R,Zusman RM,Haig A,Flavin S,MacDonald B

更新日期：2003-02-01 00:00:00

abstract：:To evaluate the possible physiologic role of atrial natriuretic factor (ANF) in the observed dissociation of aldosterone secretion from the renin-angiotensin system during hypoxic exercise, 12 untrained men, ages 18 to 24, were studied on two separate days for 30 min during hypoxic (16% O2) and normoxic (room air) exe...

journal_title：American journal of hypertension

authors： Lawrence DL,Shenker Y

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:In the United States, roughly one-third of adults have hypertension; another third have prehypertension. The prevalence of hypertension in deaf American Sign Language (ASL) users is unknown. We address this gap through a descriptive study for the prevalence of hypertension in the American Deaf community and ...

journal_title：American journal of hypertension

authors： Simons AN,Moreland CJ,Kushalnagar P

更新日期：2018-10-15 00:00:00

abstract：BACKGROUND:We investigated the effects of percutaneous transluminal renal angioplasty on left ventricular (LV) mass, and the impact of LV mass reduction on outcomes. METHODS:A total of 144 hypertensive patients with renal artery stenosis (RAS) (mean age 69 years; 22.2% fibromuscular dysplasia (FMD)) who underwent angi...

journal_title：American journal of hypertension

authors： Iwashima Y,Fukuda T,Horio T,Kusunoki H,Hayashi SI,Kamide K,Kawano Y,Ishimitsu T,Yoshihara F

更新日期：2020-05-21 00:00:00

abstract：:Nitric oxide synthase (NOS) blockade increases blood pressure (BP) and modifies glomerular and tubular function. Angiotensin II (AII) blockade restores glomerular and tubular function but does not lower BP. We measured plasma renin activity (PRA), plasma (AIIp), and kidney tissue (AIIk) AII with radioimmunoassay to in...

journal_title：American journal of hypertension

authors： Garcia GE,Brown MR,Wead LM,Braun S,Gabbai FB

更新日期：1997-10-01 00:00:00

abstract：:Smooth muscle cells from spontaneously hypertensive rats (SHR) proliferate in culture faster than those isolated from sex- and age-matched Wistar-Kyoto (WKY) animals. There was no difference in the kinetics of S6 kinase activation in the two cultures, but later metabolic events associated with proliferation were stimu...

journal_title：American journal of hypertension

authors： Scott-Burden T,Resink TJ,Hahn AW,Bühler FR

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Hypertension has recently been identified as the leading risk factor for global mortality. This study aims to present the national prevalence of hypertension and prehypertension and, their determinants in Vietnamese adults. METHODS:Nationally representative data were obtained from the National Adult Overwei...

journal_title：American journal of hypertension

authors： Do HT,Geleijnse JM,Le MB,Kok FJ,Feskens EJ

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Coffee is a rich source of antioxidative polyphenols, but epidemiological studies and interventional trials have failed to demonstrate any clear beneficial effects of coffee consumption on hypertension. The interaction between hydroxyhydroquinone (HHQ) and 5-caffeoylquinic acid (CQA) was examined, in an atte...

journal_title：American journal of hypertension

authors： Suzuki A,Fujii A,Jokura H,Tokimitsu I,Hase T,Saito I

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The independent prognostic significance of the metabolic syndrome (MetS) in the elderly is not yet clear. We investigated the association between MetS and cardiovascular risk (composite endpoint of stroke and coronary events) in elderly treated hypertensive patients. METHODS:Cardiovascular outcome was evalu...

journal_title：American journal of hypertension

authors： Pierdomenico SD,Pierdomenico AM,Di Tommaso R,Coccina F,Di Carlo S,Cuccurullo F,Porreca E

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The prevalence of childhood elevated blood pressure (BP) has increased in the United States, particularly among African Americans. The influence of maternal plasma folate levels, alone or in combination with maternal cardiometabolic risk factors (hypertensive disorders, diabetes, and prepregnancy obesity), o...

journal_title：American journal of hypertension

authors： Wang H,Mueller NT,Li J,Sun N,Huo Y,Ren F,Wang X

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:We examined the associations of epithelial sodium channel (ENaC) genes with blood pressure (BP) changes and hypertension incidence in a longitudinal family study. METHODS:A total of 2,755 Han Chinese participants of the Genetic Epidemiology Network of Salt Sensitivity (GenSalt) baseline examination were eli...

journal_title：American journal of hypertension

authors： Yang X,He J,Gu D,Hixson JE,Huang J,Rao DC,Shimmin LC,Chen J,Rice TK,Li J,Schwander K,Kelly TN

更新日期：2014-11-01 00:00:00

abstract：:Use of thiazide diuretics and beta-blockers in the treatment of hypertension may result in metabolic derangements and/or disturbances in the parameters of renal function, which offset the benefits of blood pressure reduction by adversely affecting other cardiovascular risk factors, particularly in special patient grou...

journal_title：American journal of hypertension

authors： Tuck ML,Bravo EL,Krakoff LR,Friedman CP

更新日期：1990-12-01 00:00:00

abstract：:Cardiovascular morbid events occur as a consequence of vascular and cardiac disease, which can be identified long before symptoms of organ involvement become apparent. Early detection of abnormalities in the small arteries, especially deficiency of endothelial nitric oxide bioactivity, and of structural changes of rem...

journal_title：American journal of hypertension

authors： Cohn JN

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Ryanodine receptor (RyR) dysfunction in skeletal muscle (RyR1) leads to malignant hyperthermia, and in cardiac muscle (RyR2) triggers cardiac arrhythmias. We hypothesized that RyR dysfunction in vascular smooth muscle could increase vascular resistance and hypertension, and may contribute to increased atrial...

journal_title：American journal of hypertension

authors： Lee JS,Greco L,Migirov A,Li Y,Gerdes AM,Zhang Y

更新日期：2020-04-29 00:00:00

abstract：BACKGROUND:This study was designed to evaluate whether plasma asymmetric dimethylarginine (ADMA) has any role in predicting hemodynamic responses in clinically healthy young subjects. ADMA, as an endogenous nitric oxide (NO) synthase inhibitor, has been demonstrated to associate with hypertension and vascular reactivit...

journal_title：American journal of hypertension

authors： Päivä H,Kähönen M,Lehtimäki T,Raitakari OT,Jula A,Viikari J,Alfthan G,Juonala M,Laaksonen R,Hutri-Kähönen N

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Overweight/obese young men have increased sympatho-excitation to cold and pain stress-induced by the cold pressor test (CPT) that may lead to abnormal hemodynamic responses. Concurrent CPT and exercise may augment the sympathetic-induced increases in aortic blood pressure (BP), pressure wave reflection (augm...

journal_title：American journal of hypertension

authors： Kalfon R,Campbell J,Alvarez-Alvarado S,Figueroa A

更新日期：2015-11-01 00:00:00

abstract：:The "totality" of hypertension clinical trial endpoint data has shown that the absolute benefit of pharmacological blood pressure (BP) lowering is directly related to the BP level and baseline cardiovascular risk, albeit with attenuation of the relative risk reduction per unit of BP lowering in patients with diabetes ...

journal_title：American journal of hypertension

authors： Flack JM,Nolasco C,Levy P

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Both increased night blood pressure (BP) and nondipping are associated with worse cardiovascular risk and prognosis. However, as they are often related features, their relative importance has been difficult to assess separately. In this study we address separate associations of nocturnal hypertension and non...

journal_title：American journal of hypertension

authors： de la Sierra A,Gorostidi M,Banegas JR,Segura J,de la Cruz JJ,Ruilope LM

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The ratio of urinary concentrations of tetrahydrocortisol plus allotetrahydrocortisol to tetrahydrocortisone [(THF + ATHF)/THE] reflects the activity of the enzyme 11beta-hydroxysteroid dehydrogenase type 2 (11BHSD2), which converts cortisol to cortisone in the kidney and thereby protects the mineralocortico...

journal_title：American journal of hypertension

authors： Melander O,Frandsen E,Groop L,Hulthén UL

更新日期：2003-09-01 00:00:00