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Imidazolopyrazinones as potential antioxidants.

Abstract：

:A series of imidazolopyrazinones 3, substituted at C-2, and C-2/C-6, has been prepared. The compounds behaved as quenchers of superoxide anion. The more active compounds are structurally related to coelenterazine, a natural substrate of marine bioluminescence. Theoretical parameters based on Hartree-Fock instabilities have been examined.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Devillers I,Dive G,De Tollenaere C,Falmagne B,de Wergifosse B,Rees JF,Marchand-Brynaert J

doi

10.1016/s0960-894x(01)00445-0

subject

Has Abstract

pub_date

2001-09-03 00:00:00

pages

2305-9

issue

17

eissn

0960-894X

issn

1464-3405

pii

S0960894X01004450

journal_volume

11

pub_type

杂志文章

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