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Kinetics study of a selenium-containing ScFv catalytic antibody that mimics glutathione peroxidase.

Abstract：

:The steady state kinetic study and some enzymic characterization of a selenium-containing scFv catalytic antibody (Se-scFv2F3) was carried out. A novel reaction formula of this abzyme-catalyzed reaction was proposed and a rate equation was gotten according to the formula. The constants in the equation were compared with Dalziel's parameters and the exact meanings of these constants were analyzed. The gotten kinetics parameters from the kinetics study of Se-scFv2F3 were analyzed and compared with that of native glutathione peroxidase.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Su D,You D,Ren X,Luo G,Mu Y,Yan G,Xue Y,Shen J

doi

10.1006/bbrc.2001.5183

subject

Has Abstract

pub_date

2001-07-20 00:00:00

pages

702-7

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(01)95183-6

journal_volume

285

pub_type

杂志文章

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