Abstract:
OBJECTIVE:This study was designed mainly to establish the rates of response to valsartan 80mg once daily (qd) and to valsartan 160mg qd given to non-responders to 80mg qd, as well as to determine the safety of valsartan and the blood pressure control achieved using valsartan over a period of 24 h or more, using ambulatory blood pressure monitoring (ABPM) devices. METHODS:This was a single-blind, single-arm, multicenter study involving 256 out-patients with mild-to-moderate essential hypertension. After previous antihypertensive treatments had been 'washed out', the patients were entered into a 2-week placebo run-in period to confirm the diagnosis of mild-to-moderate hypertension. Patients who, at the end of the placebo run-in period, had a mean sitting diastolic blood pressure of between 95 and 115mmHg inclusive received valsartan 80mg qd for 4 weeks. Non-responders (those not demonstrating a diastolic blood pressure of less than 90mmHg or a decrease in diastolic blood pressure of 10mmHg or more compared with baseline) received valsartan 160mg qd for another 4 weeks. In selected centers, patients who agreed also had their blood pressure monitored for 24 h, provided their blood pressure was shown to be controlled. Of these patients, half skipped one dose of valsartan and were monitored for an additional 24h period. RESULTS:The rate of response to valsartan 80mg was 45.4%, and of those not responding to this dose, 36.3% responded to valsartan 160mg. The response rate to one or other dose was 63.2%. The ambulatory blood pressure data support a consistent reduction of blood pressure with valsartan over a 24h period and for up to 32 h after dosing in those who missed a dose. The overall incidence of adverse experiences per person-year, treatment related or otherwise, was 6.3 and 10.6 for the valsartan and placebo study periods respectively. CONCLUSION:Antihypertensive treatment with valsartan for 8 weeks produced a significant decrease in diastolic blood pressure in hypertensive patients. In addition, the drug may be safely administered, and the results of 24 h/48 h ambulatory monitoring demonstrate that valsartan is a true once-a-day antihypertensive.
journal_name
Blood Press Monitjournal_title
Blood pressure monitoringauthors
Lasko BH,Laplante A,Hébert D,Bonnefis-Boyer Sdoi
10.1097/00126097-200104000-00005subject
Has Abstractpub_date
2001-04-01 00:00:00pages
91-9issue
2eissn
1359-5237issn
1473-5725journal_volume
6pub_type
临床试验,杂志文章,多中心研究abstract:OBJECTIVE:The German Hypertension League (Deutsche Hochdruckliga) established a program to assess the accuracy and reliability of blood pressure (BP)-measuring devices in 1999 (Quality Seal Protocol). Here, we report on the results of a testing series of 105 devices designed for BP self-measurement. METHODS:The test p...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000186
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:The objective of this study was to assess the effect of feedback on medium-term blood pressure (BP) measurement skills in medical students versus a control group. METHODS:A randomized controlled trial in first-year medical students was conducted. After theoretical-practical training on measuring BP, the stu...
journal_title:Blood pressure monitoring
pub_type: 杂志文章,随机对照试验
doi:10.1097/MBP.0000000000000433
更新日期:2020-06-01 00:00:00
abstract::BACKGROUND: Blood pressure measurements taken in the clinic or laboratory are assumed to generalize to the world outside. This is true both of casual blood pressure measurements and of changes in blood pressure responses to stress. Such generalizability is crucial to the usefulness of blood pressure measurements as pr...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract:OBJECTIVE:The impact of the day of the week on home blood pressure (BP) level and day-to-day BP profile is unknown. Our objectives were to examine (i) how the initial measurement day of the week affects 3-day and 7-day mean home BP and (ii) the BP variation between different days of the week. PARTICIPANTS AND METHODS:...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000156
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVES:Monitoring of brachial blood pressure during exercise-electrocardiogram (ECG) testing is mandatory and changes in blood pressure (BP) can provide critical management evidence. Patient movement, mechanical vibration, artifactual sounds and observer variability make standard manual techniques problematic. This...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/00126097-200410000-00007
更新日期:2004-10-01 00:00:00
abstract::Some oscillometric non-invasive blood pressure (NIBP) monitors use twin-hose cuffs, whereas others use single-hose cuffs. The incompatibility hinders the transfer of patients from monitors using a single-hose cuff to monitors using twin-hose cuffs and vice versa. In particular, the Propaq Encore uses a single-hose cuf...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:Arterial hypertension is associated with cardiovascular morbidity and mortality. It was previously shown that left atrium volume increase associated with mortality and atherosclerotic heart disease. The aim of the present study was to demonstrate the value of endothelial dysfunction in predicting left atrium...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000419
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:End-stage renal disease (ESRD) is complicated by high blood pressure (BP) and severe atherosclerosis, which may lead to different values of BP measured by invasive and noninvasive methods. However, the differences in BP values between these two methods and their possible mechanisms in ESRD have not been inve...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000026
更新日期:2014-04-01 00:00:00
abstract::The objectives of the analysis are to compare the blood pressure levels at different phases of the trial and to be sure that the effect will continue until the next dose. There are problems before the analysis for which consensus is necessary. If the overall 24 h study is the first generally recognized stage, it is di...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::This research aimed to develop a simulator capable of oscillometric pressure pulses recorded from the participants for the validation of oscillometric noninvasive blood pressure (NIBP) devices. The simulator generates the pressure pulses to the cuff connected to NIBP devices depending on the oscillometric waveforms ob...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0000000000000174
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:Psoriasis is a chronic inflammatory disorder, which is associated with high risk of metabolic comorbidities. Hypertension (HTN) is among the most common and serious associations. In this study, we aimed to evaluate HTN in psoriatic patients through office and ambulatory blood pressure monitoring (ABPM). MATE...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000489
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:To test the accuracy of a new algorithm for the BPM-100, an automated oscillometric blood pressure (BP) monitor, using stored data from an independently conducted validation trial comparing the BPM-100(Beta) with a mercury sphygmomanometer. DESIGN:Raw pulse wave and cuff pressure data were stored electronic...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/00126097-200106000-00008
更新日期:2001-06-01 00:00:00
abstract:BACKGROUND:Ambulatory blood pressure monitoring (ABPM) on the oscillometric method is applicable in patients with atrial fibrillation, but the mean pulse rate is or not similar to the ventricular rate from the Holter in atrial fibrillation patients remains unknown. METHODS:This study included 228 persistent atrial fib...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000481
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to validate the ScottCare 320 ambulatory blood pressure monitor (ABPM) using both group-level and individual-level validation procedures. The group-level validation followed a modified protocol of the European Hypertension Society's validation protocol. The individual-level vali...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0b013e32835f4fc7
更新日期:2013-06-01 00:00:00
abstract::Hypertension is highly prevalent in pediatric patients with end-stage renal disease (ESRD). Ambulatory blood pressure monitoring (ABPM) has been used to characterize the altered circadian blood pressure patterns in ESRD in order to improve our understanding of the blood pressure dysregulation that occurs in these chil...
journal_title:Blood pressure monitoring
pub_type: 杂志文章,评审
doi:
更新日期:1999-06-01 00:00:00
abstract::Thomas G. Pickering spent most of his scientific career in carrying out research on clinical hypertension and blood pressure (BP) measurement. In our review of Pickering's seminal work, we first focused on white-coat hypertension and masked hypertension, two terms that he had introduced. Next, we highlighted the early...
journal_title:Blood pressure monitoring
pub_type: 传,历史文章,杂志文章
doi:10.1097/MBP.0b013e3283380e1e
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to determine the accuracy of the Microlife WatchBP O3 monitor for ambulatory blood pressure (BP) measurement according to the new ISO81060-2 2018 protocol. METHODS:The WatchBP O3 was first tested in 97 subjects from the general population (mean age, 71.3 years; 48 men) using four cuf...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000459
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:The auscultatory method is influenced by the hearing level of the observers. If the observer has hearing loss, it is possible to measure blood pressure inaccurately by misreading the Korotkoff sounds at systolic blood pressure (SBP) and diastolic blood pressure (DBP). Because of the potential clinical problem...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000016
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:We evaluated the Tiba Medical Ambulo 2400 ambulatory blood pressure monitor accuracy by both the International Standards Organization (ISO) Standard and the British Hypertension Society (BHS) protocol. METHODS:We tested children, adolescents, and adults. The requirements for both ISO and BHS were completed f...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0b013e32833c8b39
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:In the ongoing Nigerian Population Research on Environment Gene and Health (NIPREGH), we are applying standardized epidemiologic methods to determine cardiovascular phenotypes including blood pressure (BP) among adult Black Africans of Nigerian origin. We present the quality control of the conventionally meas...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0000000000000053
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the prevalence and associated factors of masked hypertension in obese patients in Yaounde. METHODS:We carried out a cross-sectional study from January to September 2017 at the National Obesity Center of the Yaounde Central Hospital. Masked hypertension was defined wh...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0000000000000457
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The nondipper pattern in hypertension is associated with worse cardiovascular outcomes. In this study, we hypothesized that high copeptin levels could predict nondippers among hypertensive patients and investigated the associations between copeptin levels and nondipper pattern in newly diagnosed hypertensive...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0000000000000123
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:In young and middle age, women have higher orthostatic intolerance (OI) than men, and hemodynamic differences have been found supporting this finding. In older people, these sex differences are less studied. Our aim was to contribute evidence. METHODS:Two hundred and twenty-four community-dwelling older par...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0b013e3283353199
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To analyze whether the number of blood pressure registrations per hour and/or different ways of defining day and night have any influence on the result of ambulatory blood pressure monitoring. DESIGN AND METHODS:The study used blood pressure data from 40 normotensive subjects (20 men) and 40 (20 men) treated...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/00126097-200110000-00005
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Measuring blood pressure (BP) requires an appropriate BP cuff size given measured mid-arm circumference (mid-AC). OBJECTIVE:To provide mid-AC means and percentiles for US population aged more than 3 years and examine the frequency distribution of mid-AC cuffed by Baum and Welch Allyn cuff systems. PATIENTS...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0000000000000349
更新日期:2018-12-01 00:00:00
abstract::To determine the accuracy of the large-extra large-sized (L-XL) cuff (32-52 cm) coupled to a Microlife WatchBP Office ABI blood pressure measuring device tested according to the requirements of the International Protocol of the European Society of Hypertension. The L-XL cuff tested in this study is designed to provide...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:10.1097/MBP.0b013e328344c73c
更新日期:2011-04-01 00:00:00
abstract::OBJECTIVE: To determine whether the evening intake of 5 mg melatonin affects 24 h arterial blood pressure and heart-rate profiles. METHODS: Twenty-one young normotensive subjects were administered placebo or melatonin for 4 weeks, according to a cross-over double-blind design, and were subjected to ambulatory blood pr...
journal_title:Blood pressure monitoring
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract:BACKGROUND:There is increasing evidence that the method of calibration directly influences the association between brachial systolic blood pressure (bSBP) and estimated aortic systolic blood pressure (aSBP) and subsequently affects prognostic and diagnostic differentiation power of the latter. OBJECTIVE:The aim of thi...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0000000000000319
更新日期:2018-06-01 00:00:00
abstract::Current hypertension guidelines continue to base management decisions on the office BP as recorded by mercury sphygmomanometry. The imminent disappearance of mercury from the workplace for environmental and safety reasons provides an opportunity to re-assess how a diagnosis of hypertension is made. There are now sever...
journal_title:Blood pressure monitoring
pub_type: 共识发展会议,杂志文章,评审
doi:10.1097/00126097-200412000-00002
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Fixed-ratio and slope-based algorithms are used to derive oscillometric blood pressure (BP). However, a paucity of published data exists assessing the accuracy of these methods. Our objective was to determine the accuracy of fixed-ratio and slope-based algorithms in healthy adults and in adults with cardiova...
journal_title:Blood pressure monitoring
pub_type: 临床试验,杂志文章
doi:10.1097/MBP.0000000000000356
更新日期:2019-02-01 00:00:00