Molecular characterization and phylogenetic analysis of a human T cell leukemia virus type 2 strain from French Guiana.

abstract：:Serum specimens (n = 1899) were assayed for infections with HTLV-I, HTLV-II, and HIV-1 in seven classified groups of normal healthy controls, children, pregnant women, prostitutes, intravenous drug abusers, patients under going hemodialysis, and hemophiliacs in South and North Vietnam. Surprisingly, 125 of 954 samples...

journal_title：AIDS research and human retroviruses

authors： Fukushima Y,Takahashi H,Hall WW,Nakasone T,Nakata S,Song P,Dinh Duc D,Hien B,Nguyen XQ,Ngoc Trinh T

更新日期：1995-05-01 00:00:00

abstract：:We studied the ability of several polyionic compounds, previously shown to have activity in vitro against human immunodeficiency virus (anti-HIV) to block binding of anti-CD4 and recombinant HIV gp120 to the CD4 receptor on human lymphocytes. We found that Evans blue and aurin tricarboxylic acid could completely inhib...

journal_title：AIDS research and human retroviruses

authors： Weaver JL,Gergely P,Pine PS,Patzer E,Aszalos A

更新日期：1990-09-01 00:00:00

abstract：:Susceptibility to HIV infection was examined in macrophages differentiated from human monocytes by macrophage colony-stimulating factor (M-CSF) or granulocyte/macrophage colony-stimulating factor (GM-CSF). The replication of macrophage-tropic human immunodeficiency virus type-1 (HIV-1), which was determined by reverse...

journal_title：AIDS research and human retroviruses

authors： Matsuda S,Akagawa K,Honda M,Yokota Y,Takebe Y,Takemori T

更新日期：1995-09-01 00:00:00

abstract：:In order to shed light on the nature of the persistent reservoir of human immunodeficiency virus type 1 (HIV-1), we investigated signs of recent evolution in the pool of proviral DNA in patients on successful HAART. Pro-viral DNA, corresponding to the C2-V3-C3 region of the HIV-1 env gene, was collected from PBMCs iso...

journal_title：AIDS research and human retroviruses

authors： Mens H,Pedersen AG,Jørgensen LB,Hue S,Yang Y,Gerstoft J,Katzenstein TL

更新日期：2007-01-01 00:00:00

abstract：:The measurement of antiretroviral concentrations in hair is emerging as an important technology to objectively quantify adherence to combination antiretroviral therapy. Hair levels of antiretrovirals are the strongest independent predictor of virologic success in large prospective cohorts of HIV-infected patients and ...

journal_title：AIDS research and human retroviruses

authors： Gandhi M,Yang Q,Bacchetti P,Huang Y

更新日期：2014-01-01 00:00:00

abstract：:We analyzed the HIV-1 pol gene from patients in Cape Town to determine the genetic diversity of HIV-1 in the region and to assess the baseline HIV-1 resistance level of treatment-naive patients. Plasma was collected prior to the national antiretroviral therapy (ART) program. RNA was extracted, followed by RT-PCR and a...

journal_title：AIDS research and human retroviruses

authors： Jacobs GB,Laten A,van Rensburg EJ,Bodem J,Weissbrich B,Rethwilm A,Preiser W,Engelbrecht S

更新日期：2008-07-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6), a lymphotropic herpesvirus, has been suggested as a potential cofactor in the acquired immunodeficiency syndrome (AIDS). Previous studies indicate that HHV-6 has a restricted range of susceptible species. In this study, we tested the in vitro susceptibility to HHV-6 of Macaca nemestrina (p...

journal_title：AIDS research and human retroviruses

authors： Lusso P,Secchiero P,Crowley RW

更新日期：1994-02-01 00:00:00

abstract：:Depletion of mitochondrial DNA (mtDNA) and mtDNA-encoded respiratory chain proteins in subcutaneous (SC) fat from patients with HIV lipoatrophy have clearly demonstrated the role of mitochondrial dysfunction in this syndrome. Research in HIV lipoatrophy, however, has been severely hampered by the lack of a suitable su...

journal_title：AIDS research and human retroviruses

authors： Shikuma CM,Gerschenson M,Chow D,Libutti DE,Willis JH,Murray J,Capaldi RA,Marusich M

更新日期：2008-10-01 00:00:00

abstract：:A sharp increase in the number of people living with HIV has been documented in the Philippines. In response, the government has instituted antiretroviral therapy (ART) nationwide through HIV treatment hubs. However, no data presently exist on the status of ART drug-resistance-associated mutations (DRMs). In this stud...

journal_title：AIDS research and human retroviruses

authors： SahBandar IN,Samonte G,Telan E,Siripong N,Belcaid M,Schanzenbach D,Leano S,Chagan-Yasutan H,Hattori T,Shikuma CM,Ndhlovu LC

更新日期：2017-11-01 00:00:00

abstract：:Low albumin levels have been associated with HIV progression. The objective of this analysis was to confirm this association and to further examine the effect of albumin before and after HIV seroconversion on disease progression. The association was first examined among individuals already infected with HIV at entry i...

journal_title：AIDS research and human retroviruses

authors： Mehta SH,Astemborski J,Sterling TR,Thomas DL,Vlahov D

更新日期：2006-01-01 00:00:00

abstract：:A potential strategy to combat the worldwide AIDS epidemic is to develop a vaginal microbicide that prevents the sexual transmission of HIV-1. One approach for preventing vaginal HIV transmission is to block the viral coreceptor CCR5 with naturally occurring chemokine ligands. In this study, we used a cynomolgus macaq...

journal_title：AIDS research and human retroviruses

authors： Kish-Catalone T,Pal R,Parrish J,Rose N,Hocker L,Hudacik L,Reitz M,Gallo R,Devico A

更新日期：2007-01-01 00:00:00

abstract：:To evaluate the efficacy, safety and tolerability of switching to a dolutegravir (DTG)-based regimen in a cohort of virological suppressed HIV-infected patients. The dynamics of total HIV-DNA and levels of high-sensitivity c-reactive protein (hsCRP), interleukin-6 (IL-6), soluble-CD14 (sCD14) and D-Dimer were also ana...

journal_title：AIDS research and human retroviruses

authors： Di Carlo D,Falasca F,Palermo E,Mezzaroma I,Fimiani C,Siccardi G,Celani L,Di Campli FM,d'Ettorre G,Antonelli G,Turriziani O

更新日期：2021-01-24 00:00:00

abstract：:We studied 123 samples from adult chronic HIV patients initiating HAART from various centers around a newly established clinical trial site in Pretoria. Each sample was sequenced in at least one structural gene (pol, gag, and env) or functional gene (vif, vpr, and vpu). A subset of 25 samples was subjected to near ful...

journal_title：AIDS research and human retroviruses

authors： Musyoki A,Mothapo K,Rakgole J,Lukhwareni A,Bessong P,Selabe G,Bredell H,Williamson C,Mphahlele MJ

更新日期：2012-09-01 00:00:00

abstract：:Recombination contributes substantially to the genetic diversity of HIV-1, and mosaic strains arise frequently, especially in populations in which multiple subtypes circulate. Yunnan, which borders the "Golden triangle" region of Southeast Asia in the south, was considered as the epicenter of China. B, CRF01_AE, CRF07...

journal_title：AIDS research and human retroviruses

authors： Li L,Chen L,Yang S,Liu Y,Li H,Bao Z,Wang Z,Zhuang D,Liu S,Li J

更新日期：2010-06-01 00:00:00

abstract：:A workshop entitled "Regulatory T cells (T(reg)) and HIV/AIDS" was held in Cincinnati, OH, September 7-8, 2006. This workshop was the first completely dedicated to T(reg) in HIV infection, and gathered investigators working on different aspects of T(reg) biology, and on HIV pathogenesis. We report here the major topic...

journal_title：AIDS research and human retroviruses

authors： Chougnet CA,Shearer GM

更新日期：2007-07-01 00:00:00

abstract：:T epitope mapping in human immunodeficiency virus proteins provides a useful tool for AIDS vaccine design. We have previously shown that four peptides selected from the Gag polyprotein of HIV-1 were able to prime mice for in vitro lymphoproliferative responses. These responses were shown to be MHC restricted, and a po...

journal_title：AIDS research and human retroviruses

authors： Vaslin B,Claverie JM,Benveniste O,Barre-Sinoussi FC,Dormont D

更新日期：1994-10-01 00:00:00

abstract：:We have studied a woman with transfusion-acquired HIV who appears to have contained infectious virus to consistently undetectable levels over a 13-year period without antiviral treatment. She received the infected transfusion for intra- and postpartum blood loss immediately after delivery of her second child in 1981. ...

journal_title：AIDS research and human retroviruses

authors： Schwartz D,Sharma U,Busch M,Weinhold K,Matthews T,Lieberman J,Birx D,Farzedagen H,Margolick J,Quinn T

更新日期：1994-12-01 00:00:00

abstract：:Circulating HIV antigens and HIV specific antibodies in sera of experimentally infected chimpanzees were monitored by ELISA immunoassay, Western blot, and radioimmunoprecipitation procedures. Three of three chimpanzees given plasma from patients with AIDS or ARC tested positive for HIV antigens beginning six to ten we...

journal_title：AIDS research and human retroviruses

authors： Saxinger C,Alter HJ,Eichberg JW,Fauci AS,Robey WG,Gallo RC

更新日期：1987-01-01 00:00:00

abstract：:HIV-1 infection causes functional defects in T cells. It also leads to a progressive reduction in numbers of such cells and both CD4+ and CD8+ cells have been reported to undergo apoptosis in culture. A corresponding reduction in B cells has not been described, but these cells are also functionally altered, with repor...

journal_title：AIDS research and human retroviruses

authors： Samuelsson A,Sönnerborg A,Heuts N,Cöster J,Chiodi F

更新日期：1997-08-10 00:00:00

abstract：:The gag-homologous region of the human endogenous retrovirus K10 (HERV-K10) was amplified by PCR from human genomic DNA and was analyzed by DNA cloning, sequencing, and expression of open reading frames in the prokaryotic pATH expression system. The analysis of genomic DNA of three donors provided evidence that HERV-K...

journal_title：AIDS research and human retroviruses

authors： Mueller-Lantzsch N,Sauter M,Weiskircher A,Kramer K,Best B,Buck M,Grässer F

更新日期：1993-04-01 00:00:00

abstract：:We have evaluated the genetic diversity of HIV-1 strains infecting injecting drug users (IDUs) in Lisbon, Portugal. Heteroduplex mobility assay and/or phylogenetic analysis revealed that env (C2V3C3 or gp41) subtype B is present in 63.7% of the 135 viral samples studied, followed by subtypes G (23.7%), A (6.7%), F (5....

journal_title：AIDS research and human retroviruses

authors： Esteves A,Parreira R,Piedade J,Venenno T,Franco M,Germano de Sousa J,Patrício L,Brum P,Costa A,Canas-Ferreira WF

更新日期：2003-06-01 00:00:00

abstract：:Before the introduction of HAART, HIV-associated neurocognitive impairment (NCI) was recognized as an independent risk factor for death. Since 1996, we conducted a prospective study to assess whether NCI still represents a negative prognostic factor for mortality. Patients were administered measures of neurocognitive ...

journal_title：AIDS research and human retroviruses

authors： Tozzi V,Balestra P,Serraino D,Bellagamba R,Corpolongo A,Piselli P,Lorenzini P,Visco-Comandini U,Vlassi C,Quartuccio ME,Giulianelli M,Noto P,Galgani S,Ippolito G,Antinori A,Narciso P

更新日期：2005-08-01 00:00:00

abstract：:In this study HIV-1 subtype C-infected adults demonstrated higher purifying selection on their viral populations in reverse transcriptase (RT) than infected children. This difference is likely explained by more mature cytotoxic T-lymphocyte responses in adults, which may have implications for the development of drug r...

journal_title：AIDS research and human retroviruses

authors： Saravanan S,Gomathi S,Kausalya B,Boobalan J,Murugavel KG,Balakrishnan P,Mothi SN,Solomon SS,Kumarasamy N,Selvamuthu P,Solomon S,Smith DM

更新日期：2015-06-01 00:00:00

abstract：:To examine the genetic features of the long terminal repeat (LTR) derived from six HIV-1-infected individuals enrolled in the Mexico City Cohort, we cloned and sequenced a 505-bp fragment of the proviral LTR from their peripheral blood mononuclear cells (PBMCs). All patients harbored HIV-1 LTR quasispecies correspondi...

journal_title：AIDS research and human retroviruses

authors： Gómez-Román VR,Vázquez JA,del Carmen Basualdo M,Estrada FJ,Ramos-Kuri M,Soler C

更新日期：2000-03-20 00:00:00

abstract：:The presence of human immunodeficiency virus (HIV)-specific antibodies was examined in plasma and cervicovaginal (mucosal) samples of 24 HIV-exposed uninfected (EU) female sexual partners of HIV-infected men, and compared with findings in 18 HIV-infected and 15 low-risk HIV-uninfected women. Only HIV-infected women ha...

journal_title：AIDS research and human retroviruses

authors： Buchacz K,Parekh BS,Padian NS,van der Straten A,Phillips S,Jonte J,Holmberg SD

更新日期：2001-12-10 00:00:00

abstract：:The Human Immunodeficiency Virus (HIV), the causative agent of AIDS, is thought to bind to T4+ (CD4+) target cells through the heavily glycosylated gp120 envelope glycoprotein. Plant lectins bind glycoproteins through noncovalent interaction with specific hexose residues; therefore, lectins were evaluated for their ab...

journal_title：AIDS research and human retroviruses

authors： Robinson WE Jr,Montefiori DC,Mitchell WM

更新日期：1987-10-01 00:00:00

abstract：:The pharmacokinetics and short-term safety of atazanavir 150 and 200 mg, when coadministered with saquinavir/ritonavir 1600/100 mg once daily, were evaluated. On day 1, atazanavir 150 mg once daily, was added to saquinavir/ritonavir regimens and sampling was performed to evaluate saquinavir, ritonavir, and atazanavir ...

journal_title：AIDS research and human retroviruses

authors： Boffito M,Maitland D,Dickinson L,Back D,Hill A,Fletcher C,Moyle G,Nelson M,Gazzard B,Pozniak A

更新日期：2006-08-01 00:00:00

abstract：:The conditioned medium of a HTLV-I-carrying T cell line HUT-102 showed cytotoxic activity against a mouse fibroblast cell line L-M. We prepared the cDNA library from HUT-102 poly(A)+ RNA and screened it using oligonucleotide probes that correspond to the amino acid sequences conserved in tumor necrosis factor (TNF) an...

journal_title：AIDS research and human retroviruses

authors： Kato S,Miki T,Takahashi N,Ohmori M,Hemmi H,Numao N,Kondo K

更新日期：1989-12-01 00:00:00

abstract：:Both saponin and muramyl dipeptide (MDP) formulated with a squalane-in-water emulsion of large particle size prepared with a vortex mixer were superior to Al(OH)3 as adjuvants for HIV gp120 in mice. All the adjuvants induced IgG1 antibody, but saponin elicited the highest titers of IgG2a. The secretion of interleukin-...

journal_title：AIDS research and human retroviruses

authors： Bomford R,Stapleton M,Winsor S,McKnight A,Andronova T

更新日期：1992-10-01 00:00:00

abstract：:The HIV-1 subtype distribution in 83 HIV-1-seropositive individuals living in Greece was investigated by using the heteroduplex mobility assay (HMA), DNA sequencing, and phylogenetic analysis. The results revealed that partial HIV-1 gp120 sequences from 71 (86%) patients were subtype B, 5 (6%) were subtype A, 4 were s...

journal_title：AIDS research and human retroviruses

authors： Nasioulas G,Paraskevis D,Paparizos V,Lazanas M,Karafoulidou A,Hatzakis A

更新日期：1998-05-20 00:00:00