Extraordinary high rate of HTLV type II seropositivity in intravenous drug abusers in south Vietnam.

abstract：:HIV-1 CRF07_BC became prevalent in Taiwan after the epidemic among injection drug users (IDUs). We describe a unique recombinant form (URF) consisting of CRF01_AE and CRF07_BC (named URF_0107-H8) genes detected from an IDU. The 8.8 kb near full-length genome of URF_0107-H8 had a CRF01_AE backbone with two CRF07_BC fra...

journal_title：AIDS research and human retroviruses

authors： Lee NY,Wang JC,Lin YC,Wu CJ,Li CW,Li MC,Wang SW,Tseng FC,Ko WC

更新日期：2016-06-01 00:00:00

abstract：:To evaluate the course of liver fibrosis, 328 HIV-hepatitis C virus (HCV)-coinfected patients (210 HCV treated and 118 HCV untreated) were followed-up for 38-42 months. Liver fibrosis was assessed by biopsy or elastometry at baseline and by elastometry afterward, in addition to other noninvasive indexes. A combined li...

journal_title：AIDS research and human retroviruses

authors： Cartón JA,Collazos J,de la Fuente B,Asensi V

更新日期：2013-02-01 00:00:00

abstract：:Despite repeated exposures to HIV-1, some individuals remain seronegative. This study reports that sera from a fraction of exposed seronegative (ESN) subjects showed HIV-neutralizing activity; 5 of 17 ESN sera and none of 17 controls neutralized two different HIV-1 primary isolates (range of neutralizing titers: 1/20 ...

journal_title：AIDS research and human retroviruses

authors： Lopalco L,Pastori C,Cosma A,Burastero SE,Capiluppi B,Boeri E,Beretta A,Lazzarin A,Siccardi AG

更新日期：2000-01-20 00:00:00

abstract：:The gag-homologous region of the human endogenous retrovirus K10 (HERV-K10) was amplified by PCR from human genomic DNA and was analyzed by DNA cloning, sequencing, and expression of open reading frames in the prokaryotic pATH expression system. The analysis of genomic DNA of three donors provided evidence that HERV-K...

journal_title：AIDS research and human retroviruses

authors： Mueller-Lantzsch N,Sauter M,Weiskircher A,Kramer K,Best B,Buck M,Grässer F

更新日期：1993-04-01 00:00:00

abstract：:It has been proposed that HIV-1-neutralizing 2F5 and 4E10 monoclonal antibodies recognize gp41 ectodomain pretransmembrane sequences in the context of the membrane interface. With the aim of evaluating lipid-bilayer surface effects on recognition, we use phospholipid model systems to investigate the ability of 2F5 and...

journal_title：AIDS research and human retroviruses

authors： Sánchez-Martínez S,Lorizate M,Katinger H,Kunert R,Nieva JL

更新日期：2006-10-01 00:00:00

abstract：:Preexposure prophylaxis (PrEP) of HIV infection with tenofovir-containing regimens is effective, but plagued by poor adherence in some studies. Options for safe, effective, and acceptable PrEP products, especially for men and women at risk of HIV via receptive anal intercourse (RAI), are needed. We performed a randomi...

journal_title：AIDS research and human retroviruses

authors： Leyva F,Fuchs EJ,Bakshi R,Carballo-Dieguez A,Ventuneac A,Yue C,Caffo B,Du Y,Torbenson M,Li L,Mullin G,Lee L,Rohan L,Anton PA,Hendrix CW

更新日期：2015-11-01 00:00:00

abstract：:HIV-1 infection is associated with vascular alterations. This is accompanied by an increased risk of cardiovascular diseases and Kaposi's sarcoma, an endothelial cell-derived tumor. We investigated the impact of maternal HIV-1 infection on phenotype and gene expression of endothelial cells in newborns. For this reason...

journal_title：AIDS research and human retroviruses

authors： Jörg A,Grubert T,Grimm T,Guenzi E,Naschberger E,Samson E,Oostendorp R,Keller U,Stürzl M

更新日期：2005-11-01 00:00:00

abstract：:Anti-HIV-1-specific T cell responses in early HIV-1 infection have been found to be important in deciding the course of disease progression. But there are few data concerning nonsubtype B HIV infection. HIV-1 subtype C is the most prevalent subtype in India. HIV-1 Gag-specific T cell responses in 12 Indian subjects wi...

journal_title：AIDS research and human retroviruses

authors： Thakar MR,Patke D,Lakhashe SK,Bhonge L,Kulkarni SV,Tripathy SP,Gupte N,Brookmeyer R,Quinn TC,Paranjape RS,Bollinger RC

更新日期：2002-12-10 00:00:00

abstract：:HLA is one of the genetic factors that influence the clinical course of HIV-1 infection, and patients with HLA-B35 are prone to rapid disease progression. Nine viral epitopes that are recognized by cytotoxic T lymphocytes (CTLs) in an HLA-B35-restricted manner were determined. To examine how HIV-1 sequences are select...

journal_title：AIDS research and human retroviruses

authors： Kawana A,Tomiyama H,Takiguchi M,Shioda T,Nakamura T,Iwamoto A

更新日期：1999-08-10 00:00:00

abstract：:Because mucosal inflammation contributes to colorectal carcinogenesis, we studied the impact of intestinal infections on risk of this malignancy among people with AIDS (PWA). Using the population-based HIV/AIDS Cancer Match, which includes approximately half of all PWA in the United States, the cancer registries ascer...

journal_title：AIDS research and human retroviruses

authors： Shebl FM,Engels EA,Goedert JJ

更新日期：2012-09-01 00:00:00

abstract：:Multiple drug effect analyses with mismatched double-stranded RNA (mismatched dsRNA or Ampligen) as a core drug were performed to identify other agents and mechanisms through which mismatched dsRNA may potentiate effective therapeutic intervention in human immunodeficiency virus (HIV) infection. Antiviral activities w...

journal_title：AIDS research and human retroviruses

authors： Montefiori DC,Robinson WE Jr,Mitchell WM

更新日期：1989-04-01 00:00:00

abstract：:Genotype-based algorithms are valuable tools for the identification of patients eligible for CCR5 inhibitors administration in clinical practice. Among the available methods, geno2pheno[coreceptor] (G2P) is the most used online tool for tropism prediction. This study was conceived to assess if the combination of G2P p...

journal_title：AIDS research and human retroviruses

authors： Montagna C,De Crignis E,Bon I,Re MC,Mezzaroma I,Turriziani O,Graziosi C,Antonelli G

更新日期：2014-12-01 00:00:00

abstract：:The surface molecule CD4 plays a key role in initiating cellular entry by the human immunodeficiency virus type 1 (HIV-1), and it is now recognized as acting synergistically with select chemokine receptors (coreceptors) in the infection process. The present study was undertaken to determine whether the extracellular r...

journal_title：AIDS research and human retroviruses

authors： Esser U,Speck RF,Deen KC,Atchison RE,Sweet R,Goldsmith MA

更新日期：2000-11-20 00:00:00

abstract：:Sexual transmission of human immunodeficiency virus provides an efficient mode for virus spread and poses unique challenges to vaccine developers. Host and viral factors that affect transmission have been studied by epidemiological approaches in the human population, and some of these factors have been modeled with ex...

journal_title：AIDS research and human retroviruses

authors： Pauza CD,Horejsh D,Wallace M

更新日期：1998-04-01 00:00:00

abstract：:In recent years, increasing numbers of patients infected with HIV-1 non-B subtypes have been treated with modern antiretroviral regimens. Therefore, a better knowledge of HIV drug resistance in non-B strains is crucial. Thus, we compared the mutational pathways involved in drug resistance among the most common non-B s...

journal_title：AIDS research and human retroviruses

authors： Santoro MM,Alteri C,Ronga L,Flandre P,Fabeni L,Mercurio F,D'Arrigo R,Gori C,Palamara G,Bertoli A,Forbici F,Salpini R,Boumis E,Tozzi V,Visco-Comandini U,Zaccarelli M,Van Houtte M,Pattery T,Narciso P,Antinori A,Cecc

更新日期：2012-10-01 00:00:00

abstract：:The clinical significance of the reduced in vitro susceptibility of HIV to antiretroviral agents has been difficult to elucidate for nucleoside analogs such as zidovudine. However, the virological significance of resistance to nevirapine and other HIV-1-specific reverse transcriptase inhibitors has been established. W...

journal_title：AIDS research and human retroviruses

authors： Richman DD

更新日期：1994-08-01 00:00:00

abstract：:Older HIV-positive patients may experience reduced benefit and increased toxicities from combination antiretroviral therapies (cART) due to late diagnosis, weakened immune systems, and other age-related physiological changes. This study investigates the effect of age on time to virologic suppression and CD4 cell count...

journal_title：AIDS research and human retroviruses

authors： Szadkowski L,Tseng A,Walmsley SL,Salit I,Raboud JM

更新日期：2012-12-01 00:00:00

abstract：:Nucleotide sequences for long terminal repeat (LTR), gag, the protease gene, and pol of a human T-lymphotropic virus type 1 (HTLV-1) isolate of probable Caribbean origin (HTLV-1CH) and a Zairian isolate (HTLV-1EL) were determined providing complete proviral sequences for these isolates. These sequences were compared w...

journal_title：AIDS research and human retroviruses

authors： Ratner L,Philpott T,Trowbridge DB

更新日期：1991-11-01 00:00:00

abstract：:Abstract We assessed the viral envelope (V3-V5 region) sequence diversity from 13 HIV-1-infected Indian children from north India. All of the 13 children were found to be infected with subtype C viruses. One of the viral sequences exhibited usage of the CXCR4 coreceptor predicted by Web PSSM and Geno2pheno tools. Th...

journal_title：AIDS research and human retroviruses

authors： Prakash SS,Kalra R,Lodha R,Kabra SK,Luthra K

更新日期：2012-05-01 00:00:00

abstract：:Iron is a key factor at various stages of HIV life cycle and determines the progression of HIV infection. Data about cellular labile iron pool (LIP) in the settings of contemporary antiretroviral therapy (cART) are lacking. Yet LIP is directly related to the generation of reactive oxygen species, and may contribute to...

journal_title：AIDS research and human retroviruses

authors： Emilova R,Manolov V,Todorova Y,Yancheva N,Alexiev I,Nikolova M

更新日期：2020-07-01 00:00:00

abstract：:To eradicate human immunodeficiency virus type 1 (HIV-1) infection, a comprehensive strategy including preventive vaccine development is needed. Envelope glycoproteins (Env) play a central role in viral infection and are the major targets of humoral immune responses. Therefore, Env is a candidate vaccine antigen, and ...

journal_title：AIDS research and human retroviruses

authors： Sasaki M,Kotaki T,Khairunisa SQ,Tachibana S,Ophinni Y,Hayashi Y,Nasronudin,Kameoka M

更新日期：2020-03-01 00:00:00

abstract：:This study determined the prevalence of human immunodeficiency virus (HIV) infection and its associated factors in female sex workers (FSWs) from the municipality of Bragança in the state of Pará, Brazil. A cross-sectional study using a respondent-driven sampling method was used to investigate 137 FSWs. They were inte...

journal_title：AIDS research and human retroviruses

authors： da Costa LM,Raiol NC,Lisboa BLA,Frade PCR,Blandtt LDS,Silva-Oliveira GC,Machado LFA,Martins LC,Oliveira-Filho AB

更新日期：2019-09-01 00:00:00

abstract：:Data indicate the presence in the Seychelles Islands of a high level of human T cell leukemia/lymphoma virus type I (HTLV-I) endemicity as well as the presence of tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). We present here the results of an hospital survey performed since 1988 in La Réunion Is...

journal_title：AIDS research and human retroviruses

authors： Mahieux R,Gessain A,Truffert A,Vitrac D,Hubert A,Dandelot J,Montchamp-Moreau C,Cnudde F,Tekaia F,De Thé G

更新日期：1994-06-01 00:00:00

abstract：:Simian immunodeficiency virus (SIV) variant SIVsmmPBj14 is unique in producing an acutely lethal enteropathic syndrome in pigtail macaques. To determine whether the nature of the PBj14 disease would be attenuated by decreasing virus input and to relate tissue virus burden to the severity of disease, we infected pigtai...

journal_title：AIDS research and human retroviruses

authors： O'Neil SP,Mossman SP,Maul DH,Hoover EA

更新日期：1999-01-20 00:00:00

abstract：:We investigated the Th1 protective and regulatory T and B cell (Treg and Breg) responses to pH1N1 monovalent influenza vaccine (IIV1) in HIV-infected pregnant women on combination antiretroviral therapy (cART). Peripheral blood mononuclear cells (PBMCs) from 52 study participants were cryopreserved before and after va...

journal_title：AIDS research and human retroviruses

authors： Weinberg A,Muresan P,Richardson K,Fenton T,Dominguez T,Bloom A,Watts DH,Abzug MJ,Nachman SA,Levin MJ,P1086 Study Team.

更新日期：2015-11-01 00:00:00

abstract：:Perinatal antiretroviral (ARV) exposure has been related to hyperlactatemia and lactic acidosis in infants born to HIV-infected mothers. Our objective was to determine the incidence of these conditions during the first year of life in uninfected infants born to HIV-infected mothers and compare the data with infants bo...

journal_title：AIDS research and human retroviruses

authors： Soler-Palacín P,Martín-Nalda A,Martínez-Gómez X,Melendo S,Riudor E,Arranz JA,Espiau M,Figueras C

更新日期：2012-08-01 00:00:00

abstract：:The humoral immune response is a mechanism that potently suppresses or prevents viral infections. However, genetic diversity and resistance to antibody-mediated neutralization are serious obstacles in controlling HIV-1 infection. In this study, we isolated monoclonal antibodies from an SIV-infected macaque by using th...

journal_title：AIDS research and human retroviruses

authors： Kuwata T,Katsumata Y,Takaki K,Miura T,Igarashi T

更新日期：2011-05-01 00:00:00

abstract：:To examine the genetic features of the long terminal repeat (LTR) derived from six HIV-1-infected individuals enrolled in the Mexico City Cohort, we cloned and sequenced a 505-bp fragment of the proviral LTR from their peripheral blood mononuclear cells (PBMCs). All patients harbored HIV-1 LTR quasispecies correspondi...

journal_title：AIDS research and human retroviruses

authors： Gómez-Román VR,Vázquez JA,del Carmen Basualdo M,Estrada FJ,Ramos-Kuri M,Soler C

更新日期：2000-03-20 00:00:00

abstract：:In order to investigate how human immunodeficiency virus (HIV) gains entry to the placenta, we have performed in vitro experiments in which highly purified trophoblast cells isolated from term human placentas were examined for their susceptibility to HIV infection. Trophoblast cells were exposed to cell-free HIV-1 for...

journal_title：AIDS research and human retroviruses

authors： Douglas GC,Fry GN,Thirkill T,Holmes E,Hakim H,Jennings M,King BF

更新日期：1991-09-01 00:00:00

abstract：:An EBV-transformed lymphoblastoid B cell clone (A12) derived from peripheral blood lymphocytes of an HIV-1-infected individual is described. The immunoglobulin isotype produced by this clone was IgM, and Southern blot analysis of immunoglobulin gene rearrangement showed a monoclonal pattern. The A12 monoclonal antibod...

journal_title：AIDS research and human retroviruses

authors： Amadori A,Ciminale V,Calabro ML,Tessarollo L,Francavilla E,Chieco-Bianchi L

更新日期：1989-02-01 00:00:00