Abstract:
:The mesolimbic dopamine (DA) pathway is critical in reward-mediated behavior. Water, sucrose, and drugs of abuse all increase DA in the nucleus accumbens septi (NAcc) in adult animals. Recently our laboratory has shown that cocaine and alcohol increase DA efflux in preadolescent animals. The present study used a natural reinforcer (i.e., water) at postnatal day 25 (PND 25) to determine the sensitivity and responsiveness of this pathway. Repeated pairing of a peppermint odor with water resulted in a behavioral odor preference and an odor-elicited increase in accumbal DA. Results show that this developing pathway is functional and responsive to conditioning using a natural reinforcer and that these behavioral and neurochemical responses can be conditioned to a previously novel environmental stimulus.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Guion ED,Kirstein CLdoi
10.1002/1098-2302(2001)38:1<46::aid-dev4>3.0.co;2-subject
Has Abstractpub_date
2001-01-01 00:00:00pages
46-55issue
1eissn
0012-1630issn
1098-2302pii
10.1002/1098-2302(2001)38:1<46::AID-DEV4>3.0.CO;2-journal_volume
38pub_type
杂志文章abstract::Handedness is an aspect of hemispheric specialization whose pattern of expression may signal an unusual specialization that in turn, may underlie several developmental psychopathologies. It is generally believed that infant handedness is neither stable nor reliable and hence, cannot be used as an early marker of poten...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20161
更新日期:2006-09-01 00:00:00
abstract::Links between child maltreatment and low-grade inflammation in adulthood are well documented, but these studies often rely on adults to report retrospectively on experiences of childhood abuse. Furthermore, these findings raise questions about whether exposure to childhood maltreatment needs time to "incubate," only g...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.22031
更新日期:2020-09-08 00:00:00
abstract::Rat pups are more resistant to retroactive associative interference 3 hr after birth than 24 hr later [Cheslock et al. [2004] Developmental Science, 7, 581-598]. The present experiments tested the effect of age, retention interval and dam presence during the retention interval on odor-induced motor activity subsequent...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20456
更新日期:2010-05-01 00:00:00
abstract::Self-feeding is a critical self-care skill that unites motor abilities (e.g., grasping and transporting utensils/food to the mouth) and cognitive abilities (e.g., using a spoon as a tool). This cross-sectional study assessed self-feeding behavior in a sample of 38 children with typical development (TD) and compared it...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21861
更新日期:2019-12-01 00:00:00
abstract::Prenatal psychosocial exposures can significantly affect infant health and development. Infants with higher temperamental negativity are theorized to be more susceptible to environmental exposures. We evaluated the interaction of prenatal maternal exposures and infant temperamental negativity to predict infant cortiso...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21328
更新日期:2015-12-01 00:00:00
abstract::Previous research on the ontogeny of sodium appetite in the rat has shown that sodium deficit first engenders sodium intake at 12 days of age, whereas direct stimulation of the brain renin--angiotensin system by intracranial injection of renin increases intake of NaCl solution as early as 3 days postnatally. Similar a...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420270305
更新日期:1994-04-01 00:00:00
abstract::Whereas significant advances have been made in understanding how exposure to early adversity "gets under the skin" of children to result in long term changes in developmental outcomes, the processes by which positive social relationships become biologically embedded remain poorly understood. The aim of this study was ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21505
更新日期:2017-05-01 00:00:00
abstract::Despite the increasing attention to early life adversity and its long-term consequences on health, behavior, and the etiology of neurodevelopmental disorders, our understanding of the adaptations and interventions that promote resiliency and rescue against such insults are underexplored. Specifically, investigations o...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21775
更新日期:2019-04-01 00:00:00
abstract::The presence of context-specific communication sounds, structurally different call types related to particular situations and potentially expressing distinct emotions of the caller, were not systematically studied in infants of strepsirrhine primates. We exposed suckling's of gray mouse lemurs (Microcebus murinus) in ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20234
更新日期:2007-11-01 00:00:00
abstract::Fear conditioning studies in adults have found that posttraumatic stress disorder (PTSD) is associated with heightened fear responses and impaired discrimination. The objective of the current study was to examine the association between PTSD symptoms and fear conditioned responses in children from a highly traumatized...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21313
更新日期:2015-11-01 00:00:00
abstract::Infant gerbils were deprived of food by removing their mother from the cage for 3 hr on alternate days, during which time they remained with their father. These infants were compared with a control group which remained with their mother while the father was removed. Litters lost weight when deprived of food but they r...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420170208
更新日期:1984-03-01 00:00:00
abstract::Separate fields of inquiry indicate (a) that prenatal stress is associated with heightened behavioral and physiological reactivity and (b) that these postnatal phenotypes are themselves associated with increased susceptibility to both positive and negative environmental influences. Collectively, this work supports Plu...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21816
更新日期:2019-07-01 00:00:00
abstract::In contrast to other aspects of species-specific development, language development represents both the universal thrust of biologically based capacities and the socially differentiated results of human experience in culturally structured worlds. This article presents a theoretical approach for understanding the ways t...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420230712
更新日期:1990-11-01 00:00:00
abstract::Psychobiological convergence-the alignment of task-related changes in children's self-reported and physiological indices of reactivity-has recently emerged as a powerful correlate of children's attachment representations, but has not been explored for its association with children's self-reported attachment, with pare...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21748
更新日期:2018-12-01 00:00:00
abstract::In order to investigate the development of autonomic control and its relation to postnatal illness, healthy term, healthy preterm, and preterm infants who had recovered from respiratory distress syndrome (RDS) were seen around the expected date of their birth, 40 weeks conceptional age (C.A.), and again at 3 months co...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420160605
更新日期:1983-11-01 00:00:00
abstract::This study provides the first characterization of early developmental trajectories of corpus callosum (CC) segments in rhesus macaques using noninvasive MRI techniques and assesses long-term effects of neonatal amygdala or hippocampal lesions on CC morphometry. In Experiment 1, 10 monkeys (5 males) were scanned at 1 w...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21514
更新日期:2017-05-01 00:00:00
abstract::Lactating Mongolian gerbils, like lactating Norway rats, reliably lick some pups in their litters more than they lick others. Male gerbil pups are licked more by their dams than are their sisters and some males and some females within each litter are licked more often than are their sibs of the same sex. In the presen...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420220406
更新日期:1989-05-01 00:00:00
abstract::Rat dams differ naturally in the level of maternal care they provide to their offspring within the same litter. We explored possible mechanisms of differential maternal care focused on genetic variation. We examined single nucleotide polymorphisms in the glucocorticoid receptor, FK506-binding protein, and serotonin tr...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21770
更新日期:2018-12-01 00:00:00
abstract::An infant-controlled tactile habituation without visual control procedure was used to evaluate the ability of 32 late-preterm neonates (mean gestational age: 34 weeks) and 32 early-term neonates (mean gestational age: 38 weeks) to actively explore with hands objects varying in texture (smooth, granular). Holding time ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21295
更新日期:2015-04-01 00:00:00
abstract::The construct of homology in the development of behavior is examined using human handedness. Research on the development of hand-use preferences in infants provides some evidence that it may be homologous with adult handedness. Nevertheless, I propose that the construct of homology may not be relevant to the study of ...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21038
更新日期:2013-01-01 00:00:00
abstract::To assess claims about developmental homologies, or devologies, longitudinal data are needed. Here, we illustrate this with the debate about the purported foundational role of neonatal imitation in children's social and cognitive development. Cross-sectional studies over the past 35 years have clarified neither the pr...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/dev.21005
更新日期:2013-01-01 00:00:00
abstract::There is very little research comparing great ape and human cognition developmentally. In the current studies we compared a cross-sectional sample of 2- to 4-year-old human children (n=48) with a large sample of chimpanzees and bonobos in the same age range (n=42, hereafter: apes) on a broad array of cognitive tasks. ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21125
更新日期:2014-04-01 00:00:00
abstract::This study tested predictions regarding two hypothesized maternal immune responses influencing sexual orientation: one affecting homosexual males with high fraternal birth order and another affecting firstborn homosexual individuals whose mothers experience repeated miscarriage after the birth of the first child. Low ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21254
更新日期:2015-01-01 00:00:00
abstract::This study evaluated the immunological, hormonal, and behavioral responses of juvenile squirrel monkeys to repeated social separations of varying length. Following a 3-hr separation, lymphocyte responses to stimulation with the mitogen concanavalin A (Con A) declined significantly, and these alterations were sustained...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420240303
更新日期:1991-04-01 00:00:00
abstract::Sensory preconditioning (SPC) is a form of latent learning in which preexposure to co-occurring neutral stimuli (S1 -S2 ) permits subsequent learning to be transferred from one stimulus (S1 ) to the other (S2 ). We examined whether human infants exhibit developmental transitions in the temporal parameters of SPC by ma...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21452
更新日期:2016-11-01 00:00:00
abstract::Visual foraging is one important way that very young infants explore and learn about their environment. We recently showed that a simple stochastic dynamical model acts quantitatively like free-looking 1-month-old infants, even though it does not include any components that directly represent the perceptual-cognitive ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21165
更新日期:2014-07-01 00:00:00
abstract::Reduction of reflex startle by brief changes in prestimulation is a robust phenomenon in adults of several species. Although the phenomenon does not require structures above midbrain, it has a long and uneven developmental course. This study of human infants assessed prestimulus effects at 15 months, within a period w...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420220203
更新日期:1989-03-01 00:00:00
abstract::Eight- and 11- to 12-day-old rat pups were tested in isolation and in the presence of an anesthetized adult under cold conditions. Pups of both ages reduced rates of ultrasonic vocalization (USV) when an adult was placed into the test cage, independent of whether the adult was their dam or an unrelated male. However, ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(sici)1098-2302(199704)30:3<195::aid-dev2>
更新日期:1997-04-01 00:00:00
abstract::Features of the early postnatal environment profoundly shape later physical and behavioral phenotypes. The amount of licking/grooming that rat dams direct towards their offspring has durable consequences, including behavioral and physiological dimensions of stress reactivity, cognition, and reproductive behavior. We e...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21182
更新日期:2014-07-01 00:00:00
abstract::A question still to be answered is whether ethanol initiation has a greater effect on ethanol consumption if it occurs during adolescence than in adulthood. This study assessed the effect of ethanol initiation during adolescence or adulthood on voluntary ethanol consumption when animals were still within the same age ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21101
更新日期:2014-04-01 00:00:00