The protective effect of hochu-ekki-to (TJ-41), a Japanese herbal medicine, against HSV-1 infection in mitomycin C-treated mice.

abstract：BACKGROUND:Different phenomena can result in enlargement of mental foramen and mandibular canal. At the foreground of diagnosis is the assessment of the biological properties of the tissue which causes such detailed lesions of the skeleton. CASE REPORT:This report describes a palpable mass at the site of the mental fo...

journal_title：Anticancer research

authors： Friedrich RE,Matschke J,Wilczak W

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND/AIM:Breast cancer treatment represents a substantial amount of health-care costs and has a negative impact on womens' psychological health. Day-Surgery managment (DS) is a favorable alternative to a classic inpatient setting. In our prospective study we evaluated DS-treatment feasibility in terms of patient ...

journal_title：Anticancer research

authors： Susini T,Carriero C,Tani F,Mattioli G,Renda I,Biglia N,Nori J,Vanzi E,Bianchi S

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND/AIM:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel clinical approach to the treatment of peritoneal carcinomatosis. A well-established, not anatomic ex vivo PIPAC model was used to investigate the influence of changes in internal pressure, distance of the Micropump(©) (MIP) to the distri...

journal_title：Anticancer research

authors： Khosrawipour V,Khosrawipour T,Falkenstein TA,Diaz-Carballo D,Förster E,Osma A,Adamietz IA,Zieren J,Fakhrian K

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND/AIM:The transcription factor Y-box-binding protein 1 (YB1) is overexpressed in many types of human cancers. YB1 regulates the G1 phase of the cell cycle by controlling transcription of G1 regulators. Here, we report that YB1 is also involved in regulating G2/M phase. MATERIALS AND METHODS:YB1-depleted TKO c...

journal_title：Anticancer research

authors： Kotake Y,Arikawa N,Tahara K,Maru H,Naemura M

更新日期：2017-04-01 00:00:00

abstract：:The antitumor effect of a polyamine biosynthetic pathway inhibitor methylglyoxal bis(cyclopentylamidinohydrazone) (MGBCP) on human osteosarcoma cell lines such as KHOS-240S, MG-63 and G-292 cells, and its effect in combination with anticancer drugs such as methotrexate (MTX), adriamycin (ADM) and 4-hydroperoxyfosfamid...

journal_title：Anticancer research

authors： Sonoda J,Hibasami H,Yamada H,Fujinami S,Nakashima K,Ogihara Y

更新日期：1995-05-01 00:00:00

abstract：AIM:Hepatic resection has become the standard treatment for patients with primary or metastatic liver malignancies. The aim of our study was to evaluate the clinical outcome of hepatic resection in patients with advanced ovarian cancer (AOC). PATIENTS AND METHODS:All patients undergoing hepatic resection for AOC in ou...

journal_title：Anticancer research

authors： Neumann UP,Fotopoulou C,Schmeding M,Thelen A,Papanikolaou G,Braicu EI,Neuhaus P,Sehouli J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIM:L-type amino acid transporter 1 (LAT1) is highly expressed in various human cancers. However, the clinicopathological significance of LAT1 and 4F2 cell surface antigen (4F2hc) in patients with colorectal cancer (CRC) is unknown. The aim of this study was to clarify the prognostic significance of LAT1 exp...

journal_title：Anticancer research

authors： Ogawa H,Kaira K,Motegi Y,Yokobori T,Takada T,Katoh R,Osone K,Takahashi R,Katayama C,Oyama T,Kanai Y,Yao T,Asao T,Kuwano H,Shirabe K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND/AIM:The oxazaphosphorines, ifosfamide and cyclophosphamide, represent a class of alkylating agents. The aim of the present in vitro study was to compare antileukemic activity of 4-hydroperoxyifosfamide (4-OOH-IF) and 4-hydroperoxycyclophosphamide (4-OOH-CP). MATERIALS AND METHODS:The experiments were perfor...

journal_title：Anticancer research

authors： Opydo-Chanek M,Śladowska K,Blicharski K,Mikeš J,Fedoročko P,Niemeyer U,Mazur L

更新日期：2017-11-01 00:00:00

abstract：:Two metastasis-associated proteins, CD44v6 and NM23-H1, are expressed by normal lymphoid cells, the former serving as activation marker and the latter as a constitutive protein. CD44v6 is considered as a marker of poor prognosis of various hematological cancers but its expression was not demonstrated in childhood acut...

journal_title：Anticancer research

authors： Magyarosy E,Sebestyén A,Timár J

更新日期：2001-01-01 00:00:00

abstract：:The continuity of the subepithelial band of lamina propria-indigenous macrophages (SBLP-M) discourages commensal gut bacteria from invading the host. In this Review we analyzed the impact of a disintegrating SBLP-M in inflammatory bowel disease (IBD), which results in microbiota inflow, inadequate immune responses and...

journal_title：Anticancer research

authors： Rubio CA,Schmidt PT

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND/AIM:Radiotherapy (RT) with adjuvant hormone therapy (HT) improves prognosis in prostate cancer (PC) patients. Gonadotrophin-releasing hormone agonist (GnRHa) with luteinizing hormone-releasing hormone (LH-RH) analogues is the standard HT. High-dose antiandrogen therapy also improves survival in patients with...

journal_title：Anticancer research

authors： Buwenge M,Deodato F,Macchia G,Siepe G,Zhao X,Valicenti RK,Cilla S,Alitto AR,Ntreta M,Bisello S,Mantini G,Valentini V,Morganti AG,Cammelli S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Combination chemotherapy of irinotecan and amrubicin for advanced non-small cell lung cancer (NSCLC) has not been fully evaluated. To determine the maximum-tolerated dose (MTD), a phase I study in patients with advanced NSCLC was conducted. MATERIALS AND METHODS:Patients with stage IIIB/IV NSCLC were enroll...

journal_title：Anticancer research

authors： Hotta K,Takigawa N,Kiura K,Tabata M,Umemura S,Ogino A,Uchida A,Bessho A,Segawa Y,Shinkai T,Nogami N,Harita S,Okimoto N,Ueoka H,Tanimoto M

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND/AIM:The purpose of this study was to identify adverse prognostic factors for patients with advanced esophageal cancer undergoing chemotherapy with docetaxel, cisplatin and 5-fluorouracil (DCF). PATIENTS AND METHODS:The study cohort comprised of 45 patients with advanced esophageal cancer who underwent induc...

journal_title：Anticancer research

authors： Nakajima M,Muroi H,Kikuchi M,Takahashi M,Ihara K,Shida Y,Kurayama E,Ogata H,Yamaguchi S,Sasaki K,Sakai M,Sohda M,Miyazaki T,Kuwano H,Kato H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The antiemetic effects of serotonin receptor antagonists during chemoradiotherapy for solid tumors have never been reported. We have developed hyperthermo-chemo-radiotherapy (HCR) for esophageal cancer. However, with this treatment, the more potent the chemotherapy was, the more frequently emesis was experie...

journal_title：Anticancer research

authors： Morita M,Kuwano H,Ohno S,Kitamura K,Sugimachi K

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND/AIM:Several studies have revealed an association between single nucleotide polymorphisms (SNPs) in the VDR gene and prostate cancer (PCa) risk in European and Asian populations. To investigate whether VDR SNPs are associated with PCa risk in African-American (AA) men, nine VDR SNPs were analyzed in a case-co...

journal_title：Anticancer research

authors： Jingwi EY,Abbas M,Ricks-Santi L,Winchester D,Beyene D,Day A,Naab TJ,Kassim OO,Dunston GM,Copeland RL Jr,Kanaan YM

更新日期：2015-03-01 00:00:00

abstract：:Previous reports have shown that one copy of the chromosome 17 was frequently lost in human ovarian cancers (1). The position of the allelic deletion has not been mapped and involvement of p53 gene has not been determined. In this study, we have shown that in human ovarian carcinoma, the commonest region of allelic lo...

journal_title：Anticancer research

authors： Tsao SW,Mok CH,Oike K,Muto M,Goodman HM,Sheets EE,Berkowitz RS,Knapp RC,Lau CC

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND/AIM:Autophagy can be either tumor promotive or suppressive. We previously identified an autophagy-inducing activity in the 30-100 kDa fraction of areca-nut-extract (ANE 30-100K) and showed that several tumor cells subjected to chronic ANE 30-100K stimulation (CAS) exhibited higher resistance against stressed...

journal_title：Anticancer research

authors： Chiu CT,Liu SY,Yen CY,Liu BY,Sun ZY,Wu CY,Deng JL,Liu YC,Lin MH

更新日期：2020-01-01 00:00:00

abstract：UNLABELLED:Adenomatous polyps are precursor lesions for colorectal carcinoma. The risk of cancer development has been associated with age and size, amount of villous component and high-grade dysplasia of adenomas. The subject-related and adenoma-related risk factors for severely dysplastic lesions were further investig...

journal_title：Anticancer research

authors： Giuliani A,Caporale A,Corona M,Ricciardulli T,Di Bari M,Demoro M,Scarpini M,Angelico F

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:TNF-alpha is one of the key inflammatory cytokines and it modulates various events through several pathways. U937 myelomonocytic leukemia cells are sensitive to TNF-alpha and about 20% of these cells undergo apoptosis within 6 hours after treatment. Co-treatment of these cells with actinomycin D or cyclohexi...

journal_title：Anticancer research

authors： Nakada S,Kawano T,Saito-akita S,Iwase S,Horiguchi-Yamada J,Ohno T,Yamada H

更新日期：2001-01-01 00:00:00

abstract：AIM:The aim of the study was to identify novel biomarkers that are vital for improving management of patients with gastric cancer (GC). MATERIALS AND METHODS:An RNA-sequencing analysis was conducted using gastric tissue from patients with metastatic GC. In vitro cell functions were evaluated by siRNA-mediated knockdow...

journal_title：Anticancer research

authors： Sawaki K,Kanda M,Umeda S,Miwa T,Tanaka C,Kobayashi D,Hayashi M,Yamada S,Nakayama G,Omae K,Koike M,Kodera Y

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase-2 (Cox-2) is expressed by several types of epithelial malignancies, i.e., carcinomas, and inhibition of Cox-2 may have a therapeutic role in chemoprevention and treatment of cancer. The role of Cox-2 in non-epithelial malignancies, however, is unclear. MATERIALS AND METHODS:We investigated, b...

journal_title：Anticancer research

authors： Lassus P,Ristimäki A,Huuhtanen R,Tukiainen E,Asko-Seljavaara S,Andersson LC,Miettinen M,Blomqvist C,Haglund C,Böhling T

更新日期：2005-07-01 00:00:00

abstract：:Integrin alpha v-beta 3 is involved in tumor angiogenesis while the clinical significance of beta 3 integrin expression in colorectal cancer and lung metastases. Analysis was performed on 51 colorectal cancer patients (22 with subsequent lung metastasis and 29 without lung metastasis). Fifty-one primary tumors and 22 ...

journal_title：Anticancer research

authors： Sato T,Konishi K,Kimura H,Maeda K,Yabushita K,Tsuji M,Miwa A

更新日期：2001-01-01 00:00:00

abstract：:In screening cytotoxic agents in morphine alkaloids [TE1-10], codeinone [TE8] was cytotoxic against two human oral tumor cells lines (HSC-2 and HSG). The cytotoxic activity of codeinone (CC50=1.0-1.2 microg/mL) against HSC-2 or HSG cells was higher than that of doxorubicin (CC50=1.9-2.0 microg/mL). Human oral gingival...

journal_title：Anticancer research

authors： Kawase M,Sakagami H,Furuya K,Kikuchi H,Nishikawa H,Motohashi N,Morimoto Y,Varga A,Molnár J

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Several attempts have been made to determine whether interphase fluorescence in situ hybridization (I-FISH) on bone marrow or peripheral blood specimens is a good alternative to conventional cytogenetics (CC) in calculating the residual proportion of Philadelphia (Ph) chromosome-positive cells during treatme...

journal_title：Anticancer research

authors： Douet-Guilbert N,Morel F,Le Charpentier T,Le Bris MJ,Herry A,Morice P,Bourquard P,Abgrall JF,Berthou C,De Braekeleer M

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND/AIM:Cancer incidence and mortalities are growing worldwide, therefore research and development of more effective and less invasive treatments, such as photodynamic therapy, are needed. Herein, we investigated the methylene blue (MB) photoactivation effects in lung epithelial cells (BEAS-2B) and lung adenocar...

journal_title：Anticancer research

authors： Rodríguez-Córdova RJ,Gutiérrez-Valenzuela CA,Bojang P,Esquivel R,Hernández P,Ramos KS,Guzmán-Zamudio R,Lucero-Acuña A

更新日期：2019-07-01 00:00:00

abstract：:This trial is based on the strategy of reversing O6-methylguanine-DNA methyltransferase (MGMT)-mediated nimustine resistance by depleting MGMT activity with streptozotocin (STZ) pretreatment. Eight patients with recurrent malignant gliomas refractory to previous nimustine chemotherapy were entered in this study. Patie...

journal_title：Anticancer research

authors： Zhao KM,Chen JM,Zuo HZ,Wu Y,Zhang YP

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:Viscum album agglutinin-1 (VAA-1) is assumed to be the biologically most active ingredient of misteltoe extracts that are often used as adjuvant cancer therapy. To develop new approaches for lung cancer treatment, we evaluated the antineoplastic activity of VAA-1 alone and in combination with other chemother...

journal_title：Anticancer research

authors： Siegle I,Fritz P,McClellan M,Gutzeit S,Mürdter TE

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The description of a new method for the measurement of complexed prostate-specific antigen (cPSA) offers a new approach to the diagnosis of prostate cancer. PATIENTS AND METHODS:We measured PSA (Hybritech and Bayer), free PSA (Hybritech) and complexed PSA (Bayer) in 72 patients with prostate cancer and 128 ...

journal_title：Anticancer research

authors： Filella X,Truan D,Alcover J,Gutierrez R,Molina R,Coca F,Ballesta AM

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND/AIM:The success of proteasome inhibitors in therapy of multiple myeloma has led to their use for other malignancies. For the proteasome inhibitor bortezomib, combination therapies with histone deacetylase inhibitors, which up-regulate ubiquitin-proteasome system (UPS)-related enzymes, produce a beneficial ef...

journal_title：Anticancer research

authors： Takenokuchi M,Miyamoto K,Saigo K,Taniguchi T

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Serum autoantibodies (AAb) against mutated p53 protein have been detected in patients with invasive breast cancer of all stages. The present pilot study was conducted to investigate the use of p53 AAb titers in monitoring patients with recurrent breast cancer. PATIENTS AND METHODS:Sequential sera of 24 pati...

journal_title：Anticancer research

authors： Regele S,Vogl FD,Kohler T,Kreienberg R,Runnebaum IB

更新日期：2003-01-01 00:00:00