Abstract:
:There is some evidence that memory for temporal order is a process that may be impaired independently of other forms of memory. For example, patients with Korsakoff's syndrome have been shown to have poorer temporal-order memory than other amnesic patients, despite item memory being equivalent. Patients with schizophrenia have been reported to have a variety of memory problems, although memory for the order of events has not been examined very frequently. In this study, we tested memory for temporal order in patients with schizophrenia and in control subjects. Subjects were presented with two lists of 15 words (at two different times) and were later asked to reproduce the order of each list from a random array of the words. In both versions of the test, patients with schizophrenia were impaired in placing the items in the correct temporal order. Recall and recognition of the actual words used to comprise the lists were also impaired in the schizophrenic patients. However, when recall measures were covaried, and when patients were matched with controls for recall, post-hoc group differences in temporal memory were eliminated. In contrast, covarying recognition (indexed by d' or matching for recognition) did not eliminate group differences. Therefore, although memory for temporal order is compromised in patients with schizophrenia, this deficit is highly correlated with generally poorer item-specific memory retrieval (i.e., recall). It is possible that both impairments are due to some third process that underlies and aids in the reconstruction of episodes.
journal_name
Schizophr Resjournal_title
Schizophrenia researchauthors
Elvevåg B,Egan MF,Goldberg TEdoi
10.1016/s0920-9964(00)00014-1subject
Has Abstractpub_date
2000-12-15 00:00:00pages
187-93issue
2-3eissn
0920-9964issn
1573-2509pii
S0920-9964(00)00014-1journal_volume
46pub_type
杂志文章abstract:INTRODUCTION:Progressive atrophy occurs in brain regions involved in the working memory network along the schizophrenia's course, but without parallel evolution of working memory impairment. We investigated the functional organization inside this network at different stages of the disease. METHODS:Twenty-eight patient...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2013.10.023
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:A small but significant association between schizophrenia and violence is open to a number of explanations. Impaired empathy has been associated with schizophrenia, and with violence in the general population. Our aim was to conduct a systematic review of any research into relationships between schizophrenia...
journal_title:Schizophrenia research
pub_type: 杂志文章,评审
doi:10.1016/j.schres.2012.07.019
更新日期:2012-10-01 00:00:00
abstract::The functional integrity of the dorsolateral prefrontal cortex (DLPFC) is altered in schizophrenia leading to profound deficits in working memory and cognition. Growing evidence indicates that dysregulation of glutamate signaling may be a significant contributor to the pathophysiology mediating these effects; however,...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2007.09.022
更新日期:2007-12-01 00:00:00
abstract::Recent transcriptomic, proteomic and metabolomics studies have highlighted an abnormal cerebral glucose and energy metabolism as one of the potential pathophysiological mechanisms of schizophrenia. This raises the possibility that a metabolically-based intervention might have therapeutic value in the management of sch...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2018.11.011
更新日期:2019-04-01 00:00:00
abstract:AIM:To compare the prevalence and trends of antipsychotic drug use during pregnancy between countries across four continents. METHODS:Individually linked health data in Denmark (2000-2012), Finland (2005-2014), Iceland (2004-2017), Norway (2005-2015), Sweden (2006-2015), Germany (2006-2015), Australia (New South Wales...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2020.03.048
更新日期:2020-06-01 00:00:00
abstract::Variable levels of essential polyunsaturated fatty acids (EPUFAs) reported in schizophrenia are likely due to differences in age, sex, ethnicity, diet, life style and treatments. The present study examined the EPUFAs levels in plasma, RBC and CSF in never-medicated first-episode psychotic patients and normal controls ...
journal_title:Schizophrenia research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.schres.2007.09.036
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Quality of life (QOL) is considered an important outcome in the treatment of schizophrenia, but the determinants of QOL are poorly understood in this population. Furthermore, previous studies have relied on combined measures of subjective QOL (usually defined as life satisfaction) and objective QOL (usually d...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2007.09.001
更新日期:2008-01-01 00:00:00
abstract::The construct of Expressed Emotion (EE) is a reliable predictor of relapse in psychotic disorders globally. However, cultural differences in the level and manifestation of EE have been reported. This review was conducted in line with PRISMA guidelines to demonstrate the distribution of EE and its domains cross-cultura...
journal_title:Schizophrenia research
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.schres.2019.03.020
更新日期:2019-06-01 00:00:00
abstract::In previous studies of self-monitoring in schizophrenia, patients have exhibited reductions in the amplitude of the error-related negativity (ERN), a component of the event-related brain potential (ERP) elicited most prominently immediately following the execution of incorrect responses. In the current study, we exami...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2007.08.027
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVES:Cognitive remediation therapy (CRT) has shown significant improvement in cognition in schizophrenia. However, effect sizes of CRT have been reported to be modest raising the issue how to augment the effects of CRT on neurocognition and social cognition. Our aim was to examine whether the addition of computer...
journal_title:Schizophrenia research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.schres.2018.06.012
更新日期:2018-11-01 00:00:00
abstract::Self-determination theory (SDT) provides a model for understanding motivation deficits in schizophrenia, and recent research has focused on problems with intrinsic motivation. However, SDT emphasizes that motivated behavior results from three different factors: intrinsic motivators (facilitated by needs for autonomy, ...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2014.04.027
更新日期:2014-07-01 00:00:00
abstract::Psychotic experiences are far more common in the population than psychotic disorder. They are associated with a number of adverse outcomes but there has been little research on associations with functioning and distress. We wished to investigate functioning and distress in a community sample of adolescents with psycho...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2015.03.020
更新日期:2015-06-01 00:00:00
abstract::The role of mentalizing abilities (or theory of mind) and empathic abilities in violent behavior were studied in 24 hospitalized males with paranoid schizophrenia (ICD-10). Patients were divided into violent and nonviolent groups based on their history of committing violent acts against others. To examine these abilit...
journal_title:Schizophrenia research
pub_type: 临床试验,杂志文章
doi:10.1016/S0920-9964(03)00049-5
更新日期:2004-07-01 00:00:00
abstract::The relationship between social cognition (i.e., cognition for social stimuli) and ward behavior among individuals with chronic schizophrenia was investigated. Twenty-seven inpatients completed a battery of cognitive and social-cognitive tasks and were rated by staff on various indices of ward behavior. Overall, there...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/0920-9964(96)00010-2
更新日期:1996-07-05 00:00:00
abstract::A recent systematic review concluded that cannabis use increases risk of psychotic outcomes independently of confounding and transient intoxication effects. Furthermore, a model of the association between cannabis use and schizophrenia indicated that the incidence and prevalence of schizophrenia would increase from 19...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2009.05.031
更新日期:2009-09-01 00:00:00
abstract::Abnormalities of cerebellar structure and function, long recognized as a hallmark of chronic alcohol abuse, have also occasionally been noted in patients with schizophrenia. We used a four-point rating scale to assess clinical signs of cerebellar dysfunction in men meeting DSM-IV criteria for schizophrenia (N=34) and ...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/s0920-9964(01)00300-0
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Symptomatic remission and its associated factors have been evaluated in several studies of younger schizophrenic patients. Although the number of older individuals with schizophrenia is rapidly growing, evaluations of remission in elderly patients are scarce and limited to samples of convenience, questioning...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2010.09.003
更新日期:2011-03-01 00:00:00
abstract::Mismatch negativity (MMN) and P3a are auditory event-related potential (ERP) components that show robust deficits in schizophrenia (SZ) patients and exhibit qualities of endophenotypes, including substantial heritability, test-retest reliability, and trait-like stability. These measures also fulfill criteria for use a...
journal_title:Schizophrenia research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.schres.2014.09.042
更新日期:2015-04-01 00:00:00
abstract::Little is known about the impact of family history of psychosis on youth from community samples. To fill this gap, we compared youth with a first-degree relative with psychosis spectrum symptoms (i.e. family history of psychosis spectrum symptoms, FHPS) to youth without FHPS in a cross-sectional analysis of the Philad...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2019.12.021
更新日期:2020-02-01 00:00:00
abstract::The presence of delusions is considered a key feature of psychosis, but despite the psychopathological centrality of the concept of delusion, its definition and comprehension is a matter of continuing debate. In recent years studies showing that delusions are common in the general population have accumulated and chall...
journal_title:Schizophrenia research
pub_type: 杂志文章,评审
doi:10.1016/j.schres.2019.10.043
更新日期:2020-02-01 00:00:00
abstract::Motion-induced blindness (MIB) occurs when target stimuli are presented together with a moving distractor pattern. Most observers experience the targets disappearing and reappearing repeatedly for periods of up to several seconds. MIB can be viewed as a striking marker for the organization of cognitive functioning. In...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2005.08.012
更新日期:2006-01-31 00:00:00
abstract::This study reports findings of the Edinburgh High Risk Study four years after it began. This study is designed to explore the pathogenesis of schizophrenia by examining a large sample of young adults aged 16-25 years who are at enhanced risk of developing schizophrenia by having two close relatives with the disorder, ...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/s0920-9964(99)00225-x
更新日期:2000-11-30 00:00:00
abstract::repetitive thinking is often increased in various psychopathological conditions. However, evidence for its possible contribution to psychotic symptoms relies only on correlational analysis and has not been experimentally tested within the psychotic continuum. This research aims to examine whether repetitive thinking a...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2017.04.007
更新日期:2018-03-01 00:00:00
abstract::The rubber-hand illusion (RHI), an illusion in which tactile sensations are referred to a synthetic alien limb, is enhanced in schizophrenia patients. Somatosensory evoked responses of the illusion were compared between schizophrenia patients and normal control subjects. Schizophrenia patients had significant alterati...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/s0920-9964(03)00057-4
更新日期:2003-11-15 00:00:00
abstract:BACKGROUND:Deficient mirror neuron system (MNS)-activity is associated with social cognition deficits in schizophrenia. However, it is not known how socio-emotional contexts modulate the MNS-response. In a Transcranial Magnetic Stimulation (TMS)-experiment, we aimed to compare putative MNS-responses to action observati...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2018.07.043
更新日期:2019-02-01 00:00:00
abstract::The first phase of the Consortium on the Genetics of Schizophrenia (COGS-1) showed performance deficits in learning and memory on the California Verbal Learning Test, Second Edition (CVLT-II) in individuals with schizophrenia (SZ), compared to healthy comparison subjects (HCS). A question is whether the COGS-1 study, ...
journal_title:Schizophrenia research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.schres.2014.10.029
更新日期:2015-04-01 00:00:00
abstract::Vulnerability for schizophrenia is related, in part, to genetic predisposition. The identification of pathophysiological abnormalities associated with the disorder that are also present in unaffected family members of individuals with schizophrenia may assist in delineating the genetic contributions to vulnerability f...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2007.04.026
更新日期:2007-08-01 00:00:00
abstract:OBJECTIVE:To examine the effect of diagnosis, mood state, and anxiety on subjective wellbeing in patients with affective and non-affective psychotic disorders treated with quetiapine IR. METHODS:2175 patients with schizophrenia-spectrum (SZ, n=1681), schizoaffective (SA, n=249), and bipolar disorder (BPD, n=245) were ...
journal_title:Schizophrenia research
pub_type: 临床试验,杂志文章
doi:10.1016/j.schres.2009.03.004
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:International studies indicate that the median prevalence of psychotic experiences in children is 7%. It has been proposed that environmental stress during pregnancy may affect the neurodevelopment of the foetus and lead to a vulnerability in the child to later stressors and psychopathology. AIM:In this stu...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2013.11.006
更新日期:2014-01-01 00:00:00
abstract::Association with schizophrenia of the Abelson Helper Integration Site 1 (AHI1) gene on chromosome 6q23 and the adjacent primate-specific gene, C6orf217, was demonstrated in an inbred, Arab Israeli family sample and replicated in an Icelandic case control sample. Further support was provided by a second replication in ...
journal_title:Schizophrenia research
pub_type: 杂志文章
doi:10.1016/j.schres.2010.03.041
更新日期:2010-07-01 00:00:00