Opposite changes in predominantly docosahexaenoic acid (DHA) in cerebrospinal fluid and red blood cells from never-medicated first-episode psychotic patients.

abstract：:Prenatal viral infection has been associated with development of schizophrenia and autism. Our laboratory has previously shown that viral infection causes deleterious effects on brain structure and function in mouse offspring following late first trimester (E9) administration of influenza virus. We hypothesized that l...

journal_title：Schizophrenia research

authors： Fatemi SH,Reutiman TJ,Folsom TD,Huang H,Oishi K,Mori S,Smee DF,Pearce DA,Winter C,Sohr R,Juckel G

更新日期：2008-02-01 00:00:00

abstract：:Abnormality of P300 waveforms of event-related potentials (ERPs) has been suggested to represent an aspect of the pathophysiology of schizophrenia. Previous work points to the contribution of altered neural function in discrete brain regions in the left hemisphere to psychotic symptoms and cognitive deficits of schizo...

journal_title：Schizophrenia research

authors： Higuchi Y,Sumiyoshi T,Kawasaki Y,Matsui M,Arai H,Kurachi M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:The normal vasodilatory response to ingestion of nicotinic acid (NA) is impaired in some patients with schizophrenia. It is unclear whether the impairment is a feature of the disorder itself or to a confounding factor such as neuroleptics, caffeine or nicotine use. METHODS:To address this question in a cont...

journal_title：Schizophrenia research

authors： Turenne SD,Seeman M,Ross BM

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The InterSePT Scale for Suicidal Thinking (ISST) is a 12-item instrument for the assessment of current suicidal ideation in patients with schizophrenia and schizoaffective disorders. We report the psychometric characteristics of this new scale based on two studies. METHOD:In Study 1, 22 inpatients with schi...

journal_title：Schizophrenia research

authors： Lindenmayer JP,Czobor P,Alphs L,Nathan AM,Anand R,Islam Z,Chou JC,InterSePT Study Group.

更新日期：2003-09-01 00:00:00

abstract：:Non-compliance problems may rise to 50% among patients undergoing neuroleptic treatment. There are no direct measures available to predict compliance, if previous non-compliance is not taken into account. Attitudes towards neuroleptic treatment and insight into psychotic symptoms may vary during the course of the trea...

journal_title：Schizophrenia research

authors： Kampman O,Lehtinen K,Lassila V,Leinonen E,Poutanen O,Koivisto A

更新日期：2000-10-27 00:00:00

abstract：BACKGROUND:The concept of dose equivalence of depot medication is important for many scientific and clinical purposes. METHODS:A systematic literature search on four second-generation antipsychotics available as long-acting injectable drugs and haloperidol was conducted. We used the minimum effective dose method which...

journal_title：Schizophrenia research

authors： Rothe PH,Heres S,Leucht S

更新日期：2018-03-01 00:00:00

abstract：:We previously reported a schizophrenia associated reduction of neuronal and oligodendrocyte number in the anterior principal thalamic nucleus (APN) in a cohort of severely impaired elderly subjects with schizophrenia (SZ) relative to age matched nonpsychiatric controls (NCs). The present study was undertaken to determ...

journal_title：Schizophrenia research

authors： Byne W,Tatusov A,Yiannoulos G,Vong GS,Marcus S

更新日期：2008-12-01 00:00:00

abstract：:We examined the fractionation of executive functioning performance in ninety patients with schizophrenia, who were tested for initiation, sustained attention, switching/flexibility, attention allocation and impulsivity/disinhibition. The participants were also given tests of general intelligence and memory. We analyse...

journal_title：Schizophrenia research

authors： Chan RC,Chen EY,Cheung EF,Chen RY,Cheung HK

更新日期：2006-01-31 00:00:00

abstract：:Previous research demonstrates that people with schizophrenia have abnormally 'restricted' visual scanpaths to face and facial expression stimuli, which appear to be diagnostically specific to schizophrenia [Schizophr. Res. 55 (2002) 159; Biol. Psychiatry 52 (2002) 338]. This study examined the familial transmission o...

journal_title：Schizophrenia research

authors： Loughland CM,Williams LM,Harris AW

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The Discrimination and Stigma Scale (DISC-12) was specifically developed to measure experienced and anticipated discrimination reported by people with mental health problems. However, the length of the DISC-12 may represent a disadvantage especially in country settings with limited human capacity and infrast...

journal_title：Schizophrenia research

authors： Bakolis I,Thornicroft G,Vitoratou S,Rüsch N,Bonetto C,Lasalvia A,Evans-Lacko S

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Superior temporal gyrus (STG/BA22) volume is reduced in schizophrenia and to a milder degree in schizotypal personality disorder (SPD), representing a less severe disorder in the schizophrenia spectrum. SPD and Borderline personality disorder (BPD) are severe personality disorders characterized by social and...

journal_title：Schizophrenia research

authors： Goldstein KE,Hazlett EA,New AS,Haznedar MM,Newmark RE,Zelmanova Y,Passarelli V,Weinstein SR,Canfield EL,Meyerson DA,Tang CY,Buchsbaum MS,Siever LJ

更新日期：2009-07-01 00:00:00

abstract：:A disturbance of "minimal self," - of the immediate sense of mine-ness inherent in experience-is hypothesized to be the core disturbance in schizophrenia. Research with the Examination of Anomalous Self Experience (EASE) has demonstrated the selective aggregation of anomalous self-experiences in the schizophrenia spec...

journal_title：Schizophrenia research

authors： Madeira L,Pienkos E,Filipe T,Melo M,Queiroz G,Eira J,Costa C,Figueira ML,Sass L

更新日期：2019-09-01 00:00:00

abstract：:There is some evidence that memory for temporal order is a process that may be impaired independently of other forms of memory. For example, patients with Korsakoff's syndrome have been shown to have poorer temporal-order memory than other amnesic patients, despite item memory being equivalent. Patients with schizophr...

journal_title：Schizophrenia research

authors： Elvevåg B,Egan MF,Goldberg TE

更新日期：2000-12-15 00:00:00

abstract：OBJECTIVE:Recent years have witnessed growing interest in the role of the social environment in the development and outcomes of schizophrenia. We investigated whether neighborhood characteristics are associated with two important prognostic factors in early-course psychosis, age at onset of psychosis (AOP) and duration...

journal_title：Schizophrenia research

authors： Ku BS,Pauselli L,Manseau M,Compton MT

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Individuals with schizophrenia tend to have low levels of physical activity (PA) which contributes to high rates of physical comorbidities. Valid and reliable methods of assessing PA are essential for advancing health research. Ten years after initial validation of the Short-Form International Physical Activ...

journal_title：Schizophrenia research

authors： Duncan MJ,Arbour-Nicitopoulos K,Subramanieapillai M,Remington G,Faulkner G

更新日期：2017-01-01 00:00:00

abstract：:The minor neurological and cognitive deficits consistently reported in psychoses may reflect the same underlying brain dysfunction. Still, even in healthy individuals minor neurological abnormalities are associated with worse cognitive function. Therefore, establishing which neurological and cognitive deficits are spe...

journal_title：Schizophrenia research

authors： Mellacqua Z,Eyeson J,Orr KD,Morgan KD,Zanelli J,Lloyd T,Morgan C,Fearon P,Hutchinson G,Doody GA,Chan RC,Harrison G,Jones PB,Murray RM,Reichenberg A,Dazzan P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:We previously developed a novel method of identifying children aged 9-12 years who may be at elevated risk of developing schizophrenia and the spectrum disorders because they present a triad of putative antecedents of schizophrenia (ASz). The present study aimed to determine whether ASz children also present...

journal_title：Schizophrenia research

authors： Cullen AE,Dickson H,West SA,Morris RG,Mould GL,Hodgins S,Murray RM,Laurens KR

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Cognitive remediation (CR) aims primarily to improve cognition and functional outcomes. However, a limited number of studies reported a positive effect on symptoms. This limited effect may be because the symptom clusters considered are too broad and heterogeneous. This study explores, for the first time, the...

journal_title：Schizophrenia research

authors： Cella M,Reeder C,Wykes T

更新日期：2014-06-01 00:00:00

abstract：:Few studies have been conducted examining cytokines in cerebrospinal fluid of patients compared to healthy volunteers. The goals of this study were: 1) to report original data detailing cytokine levels in the cerebrospinal fluid (CSF) of 10 patients with a schizophrenia spectrum disorder (SSD) diagnosis and 10 healthy...

journal_title：Schizophrenia research

authors： Gallego JA,Blanco EA,Husain-Krautter S,Madeline Fagen E,Moreno-Merino P,Del Ojo-Jiménez JA,Ahmed A,Rothstein TL,Lencz T,Malhotra AK

更新日期：2018-12-01 00:00:00

abstract：:Assessment of depression in individuals who are considered to be at clinical high risk (CHR) for psychosis is important as high rates of depression have been reported in CHR individuals. The Calgary Depression Scale (CDSS) is the most widely used scale for assessing depression in schizophrenia. It has excellent psycho...

journal_title：Schizophrenia research

authors： Addington J,Shah H,Liu L,Addington D

更新日期：2014-03-01 00:00:00

abstract：:Schizoaffective patients can have neurocognitive deficits and default mode network dysfunction while being acutely ill. It remains unclear to what extent these abnormalities persist when they go into clinical remission. Memory and executive function were tested in 22 acutely ill schizoaffective patients; they also und...

journal_title：Schizophrenia research

authors： Madre M,Radua J,Landin-Romero R,Alonso-Lana S,Salvador R,Panicali F,Pomarol-Clotet E,Amann BL

更新日期：2014-11-01 00:00:00

abstract：:The EPSILON project (European Psychistric Services: Inputs Linked to Outcomes and Needs) is a cross-sectional study of the clinical and social characteristics, needs, satisfaction with services, quality of life, and service utilisation and costs for people with schizophrenia in five European sites (Amsterdam, Copenhag...

journal_title：Schizophrenia research

authors： Thornicroft G,Leese M,Tansella M,Howard L,Toulmin H,Herran A,Schene A

更新日期：2002-10-01 00:00:00

abstract：:The current study sought to expand on prior reports of the validity and reliability of the CAINS (CAINS) by examining its performance across diverse non-academic clinical settings as employed by raters not affiliated with the scale's developers and across a longer test-retest follow-up period. The properties of the CA...

journal_title：Schizophrenia research

authors： Blanchard JJ,Bradshaw KR,Garcia CP,Nasrallah HA,Harvey PD,Casey D,Csoboth CT,Hudson JI,Julian L,Lentz E,Nuechterlein KH,Perkins DO,Skale TG,Snowden LR,Tandon R,Tek C,Velligan D,Vinogradov S,O'Gorman C

更新日期：2017-07-01 00:00:00

abstract：:Although the seasonal patterns of admissions of affective disorder have been extensively studied, less attention has been given to the seasonal admission patterns of schizophrenia. The traditional method of aggregating the data over a study period, rather than analysing by year of admission may obscure potentially rel...

journal_title：Schizophrenia research

authors： Clarke M,Moran P,Keogh F,Morris M,Kinsella A,Walsh D,Larkin C,O'Callaghan E

更新日期：1998-11-30 00:00:00

abstract：:Schizophrenia is an illness characterized by positive symptoms, negative symptoms, and cognitive impairments. Cognitive impairments occur before the onset of psychosis and could reflect glutamatergic dysregulation. Thus, identifying associations between genetic variations in genes coding for glutamatergic receptors an...

journal_title：Schizophrenia research

authors： Chaumette B,Sengupta SM,Lepage M,Malla A,Iyer SN,Kebir O,ICAAR study group.,Dion PA,Rouleau GA,Krebs MO,Shah JL,Joober R

更新日期：2020-07-02 00:00:00

abstract：:Poly(A+) mRNA was extracted from the post-mortem brain of schizophrenics (9 subjects), unipolar depressives (5 subjects) and controls (10 subjects) and used to direct the in vitro translation of radiolabelled protein in a cell-free reticulocyte-lysate system. Protein species were analysed on two-dimensional gels. Over...

journal_title：Schizophrenia research

authors： Perrett CW,Whatley SA,Ferrier IN,Marchbanks RM

更新日期：1992-03-01 00:00:00

abstract：:Factor analysis was performed on OPCRIT checklist psychotic symptoms rated on 102 patients with DSM-III-R schizophrenia. An initial three-factor solution produced positive, negative, and disorganisation factors. However, application of the scree test suggested five substantive factors, with the positive factor dividin...

journal_title：Schizophrenia research

authors： Cardno AG,Jones LA,Murphy KC,Asherson P,Scott LC,Williams J,Owen MJ,McGuffin P

更新日期：1996-12-15 00:00:00

abstract：:A case-control study was conducted in Singapore, in order to examine a proposed association between schizophrenia and the HLA DQB1 gene locus. The probands were male inpatients of Chinese ethnicity with schizophrenia (ICD-10 criteria, n = 102) and the controls were adults matched for gender and ethnicity (n = 111). Po...

journal_title：Schizophrenia research

authors： Nimgaonkar VL,Rudert WA,Zhang XR,Tsoi WF,Trucco M,Saha N

更新日期：1995-12-01 00:00:00

abstract：:A prerequisite to longitudinal fMRI studies in schizophrenia is the knowledge on fMRI signal reliability in schizophrenia patients. We assessed the reproducibility of activations elicited by two fMRI sessions, which were 21 months apart, of a story listening paradigm in 10 schizophrenia patients and 10 healthy subject...

journal_title：Schizophrenia research

authors： Maïza O,Mazoyer B,Hervé PY,Razafimandimby A,Dollfus S,Tzourio-Mazoyer N

更新日期：2011-05-01 00:00:00

abstract：:Large studies investigating the psychosocial effects of lifestyle interventions in patients with a severe mental illness (SMI) are scarce, especially in residential patients. This large, randomized controlled, multicentre pragmatic trial assessed the psychosocial effects of a combined diet-and-exercise lifestyle inter...

journal_title：Schizophrenia research

authors： Stiekema APM,Looijmans A,van der Meer L,Bruggeman R,Schoevers RA,Corpeleijn E,Jörg F

更新日期：2018-09-01 00:00:00