Distribution of seizure precipitants among epilepsy syndromes.

abstract：OBJECTIVE:To define the phenotypic spectrum of phosphatidylinositol glycan class A protein (PIGA)-related congenital disorder of glycosylation (PIGA-CDG) and evaluate genotype-phenotype correlations. METHODS:Our cohort encompasses 40 affected males with a pathogenic PIGA variant. We performed a detailed phenotypic ass...

journal_title：Epilepsia

authors： Bayat A,Knaus A,Pendziwiat M,Afenjar A,Barakat TS,Bosch F,Callewaert B,Calvas P,Ceulemans B,Chassaing N,Depienne C,Endziniene M,Ferreira CR,Moura de Souza CF,Freihuber C,Ganesan S,Gataullina S,Guerrini R,Guerrot AM,

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To estimate magnetoencephalography (MEG) correlates of different types of aura in temporal lobe epilepsy (TLE). METHODS:MEG study was performed on 57 patients (26 male and 31 female) with TLE, whose ages ranged from 14-46 years (mean 27 years). Interictal magnetoencephalograms showing discharges were analyzed,...

journal_title：Epilepsia

authors： Fukao K,Inoue Y,Yagi K

更新日期：2010-09-01 00:00:00

abstract：PURPOSE:The novel antiepileptic drug (AED) levetiracetam (LEV; Keppra) has a wide therapeutic index and pharmacokinetic characteristics predicting limited drug-interaction potential. It is indicated as an add-on treatment in patients with epilepsy, and thus coadministration with valproic acid (VPA) is likely. These stu...

journal_title：Epilepsia

authors： Coupez R,Nicolas JM,Browne TR

更新日期：2003-02-01 00:00:00

abstract：:The results of surgical treatment of intractable epilepsy seizures in a group of patients investigated with the intracarotid amobarbital-pentylenetetrazol EEG test were analyzed. This diagnostic test, originally designed to distinguish a mechanism of primary from that of secondary bilateral synchrony in the EEG was al...

journal_title：Epilepsia

authors： Gloor P,Rasmussen T,Altuzarra A,Garretson H

更新日期：1976-03-01 00:00:00

abstract：:The chronicity and severity of epilepsy, as well as the presence of temporal lobe toci, appear to correlate with psychopathology. A high prevalence of psychopathology has been reported among patients who are candidates for anterior temporal lobectomy (ATL). A review of the literature indicates that episodic psychosis ...

journal_title：Epilepsia

authors： Matsuura M

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:Psychogenic nonepileptic seizures (PNES) are among the most common clinical manifestations of conversion disorder and consist of paroxysmal behavior that resembles epileptic seizures. Preliminary data from functional neuroimaging studies gave plausible evidence that limbic circuits and sensorimotor cortex might...

journal_title：Epilepsia

authors： Labate A,Cerasa A,Mula M,Mumoli L,Gioia MC,Aguglia U,Quattrone A,Gambardella A

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:To study prospectively the evolution of visual attention in children with West syndrome to evaluate its development before the onset of spasms, its possible deterioration as a consequence of epileptic disorders, and its outcome at the age of 2 years, and the possible relation between the impairment of visual at...

journal_title：Epilepsia

authors： Guzzetta F,Frisone MF,Ricci D,Randò T,Guzzetta A

更新日期：2002-07-01 00:00:00

abstract：:Why some patients with seizures are successfully treated with antiepileptic drugs (AEDs) and others prove medically intractable is not known. Inadequate intraparenchymal drug concentration is a possible mechanism of resistance to AEDs. The multiple drug resistance gene (MDR1) encodes P-glycoprotein, an energy-dependen...

journal_title：Epilepsia

authors： Tishler DM,Weinberg KI,Hinton DR,Barbaro N,Annett GM,Raffel C

更新日期：1995-01-01 00:00:00

abstract：:In order to evaluate immediate recall and learning in epileptic patients, four tests were chosen: Wechsler's memory span for digits, graphic reproduction of geometric figures from the Wechsler Memory Scale, learning of a list of words from the Rey Memory Scale, and recognition of these words. These tests were performe...

journal_title：Epilepsia

authors： Loiseau P,Strube E,Broustet D,Battellochi S,Gomeni C,Morselli PL

更新日期：1983-04-01 00:00:00

abstract：:Estrogens are essential for normal brain functions. The effects of estrogens on seizures are contradictory. More studies are necessary to determine under which conditions the estrogens have proconvulsant effects and when the estrogens may have beneficial action in patients with epilepsy. ...

journal_title：Epilepsia

authors： Velísková J,De Jesus G,Kaur R,Velísek L

更新日期：2010-07-01 00:00:00

abstract：PURPOSE:Stereotactic radiofrequency amygdalohippocampectomy (SAHE) has been modified recently in our center for the therapy of mesial temporal epilepsy (MTLE). It has promising clinical results comparable with microsurgical amygdalohippocampectomy despite smaller volume reduction of the hippocampus. We hypothesized tha...

journal_title：Epilepsia

authors： Malikova H,Liscak R,Vojtech Z,Prochazka T,Vymazal J,Vladyka V,Druga R

更新日期：2011-05-01 00:00:00

abstract：:An understanding of the basic principles of human inheritance patterns is necessary to appreciate the variety and complexity of genetic influences in the epilepsies. The various modes of human inheritance include single gene (mendelian), chromosomal, mitochondrial, and multifactorial/polygenic. Recent insights regardi...

journal_title：Epilepsia

authors： Bird TD

更新日期：1994-01-01 00:00:00

abstract：PURPOSE:The objective of this study was the isobolographic evaluation of the interactions between the novel antiepileptic drug (AED) gabapentin (GBP) and a number of other AEDs against electroconvulsion-induced convulsions in mice. METHODS:Electroconvulsions were produced by means of an alternating current (ear-clip e...

journal_title：Epilepsia

authors： Borowicz KK,Swiader M,Luszczki J,Czuczwar SJ

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:To review the clinical, neurophysiologic, and radiological data of patients with ganglioglioma who had undergone evaluation and surgery in our Epilepsy Program. METHODS:The medical and neurophysiologic records of 38 patients with intractable epilepsy and ganglioglioma were reviewed. Data underwent statistical ...

journal_title：Epilepsia

authors： Morris HH,Matkovic Z,Estes ML,Prayson RA,Comair YG,Turnbull J,Najm I,Kotagal P,Wyllie E

更新日期：1998-03-01 00:00:00

abstract：:Although it is well documented that long-term therapy with older antiepileptic drugs (AEDs) leads to an increase in risk for atherosclerosis, there has been only limited information regarding the vascular risk in patients who are treated with new AEDs. We therefore conducted a prospective longitudinal study to assess ...

journal_title：Epilepsia

authors： Kim DW,Lee SY,Shon YM,Kim JH

更新日期：2013-10-01 00:00:00

abstract：:The incidence of biochemical signs of vitamin D deficiency and the effects of vitamin D supplementation were investigated in 83 children and 95 adults on chronic antiepileptic therapy and 40 mentally retarded controls living under comparable conditions. Low 25-hydroxyvitamin D and serum calcium, and elevated immunorea...

journal_title：Epilepsia

authors： Offermann G,Pinto V,Kruse R

更新日期：1979-02-01 00:00:00

abstract：:The suppressive effect of sunglasses upon photoparoxysmal responses (PPRs) elicited by 15-Hz flicker stimuli with a low luminance of nearly 10 nits was studied in eight patients with photosensitive epilepsy. Using three commercially available sunglasses of neutral density (ND), blue, and brown, the influence upon gene...

journal_title：Epilepsia

authors： Takahashi T,Tsukahara Y

更新日期：1992-05-01 00:00:00

abstract：OBJECTIVE:To compare surgical outcome in mesial temporal lobe epilepsy (MTLE) patients with unilateral hippocampal sclerosis (MTLE-HS) who had or did not have preoperative video-electroencephalographic monitoring (VEEG). METHODS:A prospective study was undertaken with 166 consecutive pharmacoresistant unilateral MTLE-...

journal_title：Epilepsia

authors： Alvim MKM,Morita ME,Yasuda CL,Damasceno BP,Lopes TM,Coan AC,Ghizoni E,Tedeschi H,Cendes F

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To examine the inhibitory effect of anticonvulsants (AEDs) on carnitine transport by the human placental carnitine transporter. METHODS:Uptake of radiolabeled carnitine by human placental brush-border membrane vesicles was measured in the absence and presence of tiagabine (TGB), vigabatrin (VGB), gabapentin (G...

journal_title：Epilepsia

authors： Wu SP,Shyu MK,Liou HH,Gau CS,Lin CJ

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:Treatments for convulsive status epilepticus (SE) have a wide range of effectiveness. The estimated effectiveness of non-intravenous benzodiazepines (non-IV BZDs) ranges from approximately 70% to 90% and the estimated effectiveness of non-benzodiazepine antiseizure medications (non-BZD ASMs) ranges from appro...

journal_title：Epilepsia

authors： Sánchez Fernández I,Gaínza-Lein M,Barcia Aguilar C,Amengual-Gual M,Loddenkemper T

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Genetic variants in STXBP1, which encodes the conserved exocytosis protein Munc18-1, are associated with a variety of infantile epilepsy syndromes. We aimed to develop an in vivo Caenorhabditis elegans model that could be used to test the pathogenicity of such variants in a cost-effective manner. METHODS:The...

journal_title：Epilepsia

authors： Zhu B,Mak JCH,Morris AP,Marson AG,Barclay JW,Sills GJ,Morgan A

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:We studied temporal changes of brain sodium and apparent diffusion coefficient (ADC) in a temporal lobe epilepsy (TLE) rat model using kainic acid (KA). METHODS:In situ three-dimensional 23Na magnetic resonance imaging (MRI) and proton diffusion-weighted imaging (DWI) were used. KA at a dose of 10 mg/kg body w...

journal_title：Epilepsia

authors： Wang Y,Majors A,Najm I,Xue M,Comair Y,Modic M,Ng TC

更新日期：1996-10-01 00:00:00

abstract：:The progressive myoclonus epilepsies (PMEs) are a group of rare genetic disorders previously shrouded in nosological confusion. Recent advances have clarified the features of these disorders and provided a rational approach to diagnosis. The major causes of PME are now known to be Unverricht-Lundborg disease, myoclonu...

journal_title：Epilepsia

authors： Berkovic SF,Cochius J,Andermann E,Andermann F

更新日期：1993-01-01 00:00:00

abstract：:This paper addresses methodologic issues in studies of mortality, and the impact of these issues in studies of mortality in epilepsy. One important issue is to identify the question: Is it whether epilepsy increases the risk of dying? Or is it whether the underlying condition that led to epilepsy, itself associated wi...

journal_title：Epilepsia

authors： Logroscino G,Hesdorffer DC

更新日期：2005-01-01 00:00:00

abstract：:Nonconvulsive status epilepticus (SE) accounts for approximately one-quarter of all cases of SE. The actual proportion may be higher because patients with nonconvulsive SE may go unidentified. This disorder may be divided into generalized (absence) or partial (complex partial) forms. Nonconvulsive SE may occur de novo...

journal_title：Epilepsia

authors： Cascino GD

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:Pathogenic variants of KCNQ2, which encode a potassium channel subunit, cause either benign (familial) neonatal epilepsy-B(F)NE)-or KCNQ2 encephalopathy (KCNQ2 DEE). We examined the characteristics of KCNQ2 variants. METHODS:KCNQ2 pathogenic variants were collected from in-house data and two large disease da...

journal_title：Epilepsia

authors： Goto A,Ishii A,Shibata M,Ihara Y,Cooper EC,Hirose S

更新日期：2019-09-01 00:00:00

abstract：:The in vitro effects of four antiepileptic drugs (AEDs) on human sperm motility were studied with a transmembrane migration method. Sperm motility of epileptic patients receiving chronic AED therapy was also investigated. Sperm motility was measured immediately after semen had been mixed with AED and after a 2-h prein...

journal_title：Epilepsia

authors： Chen SS,Shen MR,Chen TJ,Lai SL

更新日期：1992-01-01 00:00:00

abstract：:Early in these proceedings, the origin of the three terms in the title, "idiopathic generalized epilepsy," is discussed with respect to their significance over time, and typical misunderstandings. In the mid-20th century, a rather chaotic use of a multitude of often loosely defined terms had developed, which increasin...

journal_title：Epilepsia

authors： Wolf P

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Posttraumatic epilepsy (PTE) accounts for 20% of acquired epilepsies. Experimental models are important for studying epileptogenesis. We previously reported that repetitive high-frequency oscillations with spikes (rHFOSs) occur early after lateral fluid percussion injury (FPI) and may be a biomarker for PTE. ...

journal_title：Epilepsia

authors： Reid AY,Bragin A,Giza CC,Staba RJ,Engel J Jr

更新日期：2016-10-01 00:00:00

abstract：:It is unclear whether the outcome of status epilepticus (SE), a neurological emergency associated with high mortality and morbidity, has changed over the past decade. We investigated the difference in prognosis (mortality, functional status at discharge) after adult SE episodes in a large registry between 2 time point...

journal_title：Epilepsia

authors： Fatuzzo D,Novy J,Rossetti AO

更新日期：2018-07-01 00:00:00