Abstract:
:In order to evaluate immediate recall and learning in epileptic patients, four tests were chosen: Wechsler's memory span for digits, graphic reproduction of geometric figures from the Wechsler Memory Scale, learning of a list of words from the Rey Memory Scale, and recognition of these words. These tests were performed on 200 epileptic patients over the age of 15 years, without defined cerebral lesions, and with a normal or subnormal social adjustment. Memory impairment was analyzed with respect to the following variables: seizure frequency, seizure type, duration of the disorder, and anticonvulsant medication. Patient data were compared with values obtained for a population of 100 normal subjects matched for age and level of education. Comparison between epileptics and controls clearly demonstrated a statistically significant memory impairment in the group of patients. However, the reasons for these poor performances are not clear, and none of the studied parameters (type of epilepsy, frequency of seizures, duration of the disease, and medication), if considered alone, accounts for this impairment.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Loiseau P,Strube E,Broustet D,Battellochi S,Gomeni C,Morselli PLdoi
10.1111/j.1528-1157.1983.tb04878.xsubject
Has Abstractpub_date
1983-04-01 00:00:00pages
183-92issue
2eissn
0013-9580issn
1528-1167journal_volume
24pub_type
杂志文章相关文献
EPILEPSIA文献大全abstract::The long-standing practice of polypharmacy in treating epilepsy is giving way to use of monotherapy. Monotherapy can improve seizure control as well as reduce the risk of serious idiosyncratic reactions, dose-related side effects, and complex drug interactions. Monotherapy also offers improved compliance and cost-effe...
journal_title:Epilepsia
pub_type: 杂志文章,评审
doi:10.1111/j.1528-1157.1987.tb05765.x
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:To assess the visual system excitability of photosensitive patients with idiopathic generalized epilepsy (IGE) with the paired-pulse flash-evoked potential (paired F-VEP) technique. METHODS:We studied 19 photosensitive patients with IGE (16 women) showing a photoparoxysmal electroencephalographic (EEG) respons...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2012.03411.x
更新日期:2012-04-01 00:00:00
abstract::The effects of seizures on the hypocretin/orexin system have not yet been investigated in epileptic patients. The present study aimed to assay hypocretin-1 in the cerebrospinal fluid (CSF) of patients after generalized tonic-clonic (GTC) seizures. Study groups consisted of 21 patients after GTC seizures and 19 control...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2008.01990.x
更新日期:2009-06-01 00:00:00
abstract::The possible effect of in utero antiepileptic drug (AED) exposure on the incidence of spontaneous abortion was evaluated among pregnancies of women with epilepsy and the wives of men with epilepsy. The proportion of pregnancy outcomes terminating in spontaneous abortion, the gestational age-specific rates of spontaneo...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1988.tb03745.x
更新日期:1988-07-01 00:00:00
abstract:PURPOSE:Occipital lobe epilepsy (OLE) presents in childhood with different manifestations, age of onset and EEG features that form distinct syndromes. The ictal clinical symptoms are difficult to correlate with onset in particular areas in the occipital lobes, and the EEG recordings have not been able to overcome this ...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2006.00626.x
更新日期:2006-09-01 00:00:00
abstract::Advanced variant detection in genes underlying risk of sudden unexpected death in epilepsy (SUDEP) can uncover extensive epistatic complexity and improve diagnostic accuracy of epilepsy-related mortality. However, the sensitivity and clinical utility of diagnostic panels based solely on established cardiac arrhythmia ...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.12489
更新日期:2014-02-01 00:00:00
abstract::Early treatment of prolonged seizures with benzodiazepines given intravenously by paramedics in the prehospital setting had been shown to be associated with improved outcomes, but the comparative efficacy and safety of an intramuscular (IM) route, which is faster and consistently achievable, was previously unknown. RA...
journal_title:Epilepsia
pub_type: 杂志文章,随机对照试验
doi:10.1111/epi.12284
更新日期:2013-09-01 00:00:00
abstract::We report on the cognitive-behavioral treatment of a 12-year-old boy with photogenic partial seizures with secondary generalization who had developed phobic avoidant behavior toward all kinds of situations with potential photostimulation, leading to serious impairments of life quality. Based on a behavioral analysis o...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1046/j.1528-1157.2001.24100.x
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:To investigate whether the link between epilepsy and deprivation is due to factors associated with deprivation (social causation) or factors associated with a diagnosis of epilepsy (social drift). METHODS:We reviewed electronic primary health care records from 2004 to 2010, identifying prevalent and incident...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.12942
更新日期:2015-04-01 00:00:00
abstract::Patients with epilepsy have 20-fold risk of sudden death when compared to the general population. Uncontrolled seizures is the most consistent risk factor, and death often occurs at night or in relation to sleep. We examined seizure-related respiratory disturbances in sleep versus wakefulness, focusing on periictal ox...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.13841
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the utility of baseline neuropsychological measures and scores from the intracarotid amobarbital procedure (IAP) in the prediction of postoperative memory decline in temporal lobe epilepsy surgery patients. METHODS:Logistic regression analyses were used to determine the rel...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2006.00940.x
更新日期:2007-03-01 00:00:00
abstract::Phenytoin is metabolized to its parahydroxylated derivative by hepatic microsomal enzymes. This hydroxylation is a saturable process, that is, the rate of metabolism fails to increase in proportion to the serum concentration. This leads to a nonlinear relationship between the maintenance dose of the drug and the resul...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1975.tb04745.x
更新日期:1975-11-01 00:00:00
abstract::The Commission on Classification and Terminology and the Commission on Epidemiology of the International League Against Epilepsy (ILAE) have charged a Task Force to revise concepts, definition, and classification of status epilepticus (SE). The proposed new definition of SE is as follows: Status epilepticus is a condi...
journal_title:Epilepsia
pub_type: 历史文章,杂志文章,评审
doi:10.1111/epi.13121
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:Epilepsy is a nervous system abnormality that may be caused by unknown exposures during fetal development. Studies have shown neuroprotective effects of early exposure to vitamin D in other neurological disorders, and seasonal variation in birth of children with epilepsy. We aimed to investigate if neonatal 2...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.16520
更新日期:2020-06-01 00:00:00
abstract::An understanding of the basic principles of human inheritance patterns is necessary to appreciate the variety and complexity of genetic influences in the epilepsies. The various modes of human inheritance include single gene (mendelian), chromosomal, mitochondrial, and multifactorial/polygenic. Recent insights regardi...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1994.tb05924.x
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:Self-management challenges facing adults with epilepsy include limited understanding of the condition and treatment, associated psychosocial issues, and lack of community integration. Self-management interventions improve patients' medical, life role, and emotional management. Previous interventions, develope...
journal_title:Epilepsia
pub_type: 杂志文章,随机对照试验
doi:10.1111/epi.13052
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Little is known about offspring of parents who both have idiopathic generalized epilepsy (IGE). This is of importance for understanding the complex genetic architecture of IGE. METHODS:Families in whom both parents had proven IGE were ascertained through a multiplex families database. Clinical information i...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1046/j.1528-1157.2003.07303.x
更新日期:2003-09-01 00:00:00
abstract::We conducted a retrospective parallel longitudinal cohort study comparing surgical and medical treatment for epilepsy. The surgical group contained 201 patients treated with resective surgery for epilepsy in Norway since the first operation in 1949 until January 1988. The 185 control group patients treated medically o...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1991.tb04666.x
更新日期:1991-05-01 00:00:00
abstract::Data on numbers of admissions and admission rates for all-listed and first-listed epilepsy in nonfederal short-stay hospitals are presented. These statistics are based on 232,000 hospital discharge records from a probability sample of approximately 7,000 hospitals. The patterns of admission rates for epilepsy are comp...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1981.tb04332.x
更新日期:1981-02-01 00:00:00
abstract::Status epilepticus can lead to impaired renal function, which has been attributed to complications of myoglobinuria. We confirmed changes in renal function in the absence of myoglobinuria by measuring renal hemodynamics, fluid and electrolyte excretions, and plasma levels of renin and atrial natriuretic peptide (ANP) ...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1995.tb01041.x
更新日期:1995-07-01 00:00:00
abstract:PURPOSE:To estimate magnetoencephalography (MEG) correlates of different types of aura in temporal lobe epilepsy (TLE). METHODS:MEG study was performed on 57 patients (26 male and 31 female) with TLE, whose ages ranged from 14-46 years (mean 27 years). Interictal magnetoencephalograms showing discharges were analyzed,...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2010.02655.x
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:Drebrins are crucial for synaptic function and dendritic spine development, remodeling, and maintenance. In temporal lobe epilepsy (TLE) patients, a significant hippocampal synaptic reorganization occurs, and synaptic reorganization has been associated with hippocampal hyperexcitability. This study aimed to e...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.16595
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:Deep brain stimulation has been used by several investigators to prevent the occurrence of spontaneous seizures in patients with intractable epilepsy. With the kainic acid rat model of spontaneous recurrent seizures, we examined the consequences of subthreshold electrical stimulation of commissural pathways and...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1046/j.1528-1157.43.s.5.22.x
更新日期:2002-01-01 00:00:00
abstract::Extracellular field potential recordings were made in CA3 subfield of hippocampal slices from rats aged 11-22 days. In these experiments, we analyzed the effects induced by modifying [Mg2+] in the medium (1 or 2 mM) on (a) 4-aminopyridine (4-AP, 50 microM)-induced synchronous events (including ictal- and interictal-li...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1995.tb01016.x
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVES:To advance the development of (2S,3S)-sec-butylpropylacetamide (SPD) as a new treatment for acute repetitive seizures (ARS), by studying its pharmacokinetics (PK) in pigs and its PK-pharmacodynamic (PK-PD) correlation in rats. METHODS:Two (2S,3S)-SPD intramuscular formulations (FA and FB ) were administered...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.16411
更新日期:2020-01-01 00:00:00
abstract::In 45 patients suffering from secondary generalized epilepsy, we have recorded 239 drop seizures both by radio-telemetered EEG/split-screen video taping and polygraphically. Twenty of these patients had pure tonic drop seizures. Nine patients each had myoclonic-atonic or pure atonic seizures, whereas seven had slow fa...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1157.1985.tb05671.x
更新日期:1985-09-01 00:00:00
abstract:PURPOSE:Electrical stimulation (ES) is used during intracranial electroencephalography (EEG) investigations to delineate epileptogenic areas and seizure-onset zones (SOZs) by provoking afterdischarges (ADs) or patients' typical seizure. High frequency oscillations (HFOs--ripples, 80-250 Hz; fast ripples, 250-500 Hz) ar...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2009.02389.x
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:To evaluate the natural history and mortality of chronic epilepsy in an untreated prevalence cohort of people with epilepsy (PWE) in a rural area of Bolivia. METHODS:During 1994-1996 we carried out an epidemiologic survey in a sample of 9,995 subjects in the Cordillera province. At the end of the survey we ide...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/j.1528-1167.2009.02174.x
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To investigate the characteristics of motor manifestation during convulsive epileptic and psychogenic nonepileptic seizures (PNES), captured using a wrist-worn accelerometer (ACM) device. The main goal was to find quantitative ACM features that can differentiate between convulsive epileptic and convulsive PNE...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.14619
更新日期:2019-01-01 00:00:00
abstract::It is unclear whether the outcome of status epilepticus (SE), a neurological emergency associated with high mortality and morbidity, has changed over the past decade. We investigated the difference in prognosis (mortality, functional status at discharge) after adult SE episodes in a large registry between 2 time point...
journal_title:Epilepsia
pub_type: 杂志文章
doi:10.1111/epi.14434
更新日期:2018-07-01 00:00:00