Abstract:
:The long-standing practice of polypharmacy in treating epilepsy is giving way to use of monotherapy. Monotherapy can improve seizure control as well as reduce the risk of serious idiosyncratic reactions, dose-related side effects, and complex drug interactions. Monotherapy also offers improved compliance and cost-effectiveness. The basis of monotherapy is accurate diagnosis and assessment of the patient's seizure type(s), followed by selection of a single appropriate anticonvulsant drug. Many patients currently treated with multiple anticonvulsants can be successfully converted to monotherapy with a carefully monitored program in which troublesome and redundant drugs are gradually withdrawn from the therapeutic regimen.
journal_name
Epilepsiajournal_title
Epilepsiaauthors
Wilder BJdoi
10.1111/j.1528-1157.1987.tb05765.xsubject
Has Abstractpub_date
1987-01-01 00:00:00pages
S1-7eissn
0013-9580issn
1528-1167journal_volume
28 Suppl 2pub_type
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