Abstract:
:The cell surface hydrophobicity of micro-organisms is a characteristic that has been associated with the colonization of mammalian epithelia and with their capacity to induce diseases. Melatonin is a hormone produced by the pineal gland that affects the immune response mechanism. This study investigated, as an expression of the virulence of Neisseria meningitidis, how its hydrophobic characteristics were affected by exposure to increasing concentrations of melatonin. An increase in the cell surface hydrophobicity of N. meningitidis was found at concentrations of 1 mmol l(-1), while lower concentrations of melatonin did not significantly affect this particular cell surface characteristic of the micro-organism. It may be concluded that melatonin clearly influences the cell surface hydrophobicity of N. meningitidis, a circumstance that should be taken into account in future studies to determine whether this hormone plays a role in the variable pathogenicity of the bacteria in different hosts.
journal_name
Lett Appl Microbioljournal_title
Letters in applied microbiologyauthors
Uberos J,Molina A,Liébana J,Augustin MC,Muñoz Adoi
10.1046/j.1472-765x.2000.00813.xsubject
Has Abstractpub_date
2000-10-01 00:00:00pages
294-8issue
4eissn
0266-8254issn
1472-765Xpii
lam813journal_volume
31pub_type
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journal_title:Letters in applied microbiology
pub_type: 杂志文章
doi:10.1111/j.1472-765X.2007.02281.x
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journal_title:Letters in applied microbiology
pub_type: 杂志文章
doi:10.1046/j.1472-765x.2000.00771.x
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journal_title:Letters in applied microbiology
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pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00