[Paracoccidioidomycosis of the central nervous system: case report].

Abstract:

:The involvement of the central nervous system in paracoccidioidomycosis is more frequent than previously thought. The first reference to the possibility that Paracoccidioides brasiliensis could affect the central nervous system was by Pereira & Jacobs in 1919. Since then, a great number of other studies has showed this form of clinical behavior and, in some of them, the frequency has ranged 27.27%. We report a clinical case of a 34-year-old white Brazilian woman admitted because of bacterial pneumonia. In the sixth day of admission, the patient developed cerebellar symptomatology with nausea, vomiting, dysmetria and gait disturbance. Central nervous system computer tomographic scanning disclosed a hypodense lesion in the right cerebellar hemisphere. The patient was submitted to surgery with total excision of the lesion. Histopathological examination confirmed the diagnosis of neuroparacoccidioidomycosis. Coadjuvant treatment with sulfamethoxazole-trimetoprim was introduced. The patient had a good outcome and was discharge 30 days after surgery.

journal_name

Arq Neuropsiquiatr

authors

da Silva CE,Cordeiro AF,Gollner AM,Cupolilo SM,Quesado-Filgueiras M,Curzio MF

doi

10.1590/s0004-282x2000000400024

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

741-7

issue

3A

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2000000400024

journal_volume

58

pub_type

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