Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica.

Abstract:

UNLABELLED:Tonic spasms have been most commonly associated with multiple sclerosis. To date, few reports of series of patients with neuromyelitis optica and tonic spasms have been published. METHODS:We analyzed the characteristics and frequency of tonic spasms in 19 subjects with neuromyelitis optica. Data was collected using a semi-structured questionnaire for tonic spasms, by both retrospectively reviewing medical records and performing clinical assessment. RESULTS:All patients except one developed this symptom. The main triggering factors were sudden movements and emotional factors. Spasms were commonly associated to sensory disturbances and worsened during the acute phases of the disease. Carbamazepine was most commonly used to treat the symptom and patients showed good response to the drug. CONCLUSIONS:Tonic spasms are a common clinical manifestation in patients with neuromyelitis optica.

journal_name

Arq Neuropsiquiatr

authors

Abaroa L,Rodríguez-Quiroga SA,Melamud L,Arakaki T,Garretto NS,Villa AM

doi

10.1590/0004-282X20130021

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

280-3

issue

5

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2013000500280

journal_volume

71

pub_type

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