NMO in pediatric patients: brain involvement and clinical expression.


OBJECTIVE:To analyze the clinical, neuroimaging characteristics and positivity of the acquaporin water channel (NMO-IgG) in pediatric patients with neuromyelitis optica (NMO). This disorder could have a variable clinical expression. To address such variability, the term NMO spectrum has been suggested. METHOD:We evaluated six pediatric patients, with a median age of 11 years at the time of the study, with the diagnosis of NMO by the Wingerchuck criteria. RESULTS:All the cases exhibited bilateral optic neuritis (ON). Four patients had abnormalities on brain MRI from the onset,although only three of them developed symptoms correlated to those lesions during the course of their disorder. NMO-IgG was positive in 80%. CONCLUSION:Optic neuropathy is the most impaired feature in NMO patients. Brain MRI lesions are not compatible with multiple sclerosis and positivity of the NMO-IgG are also present in NMO pediatric patients, confirming the heterogeneity in the expression of this disorder.


Arq Neuropsiquiatr


Peña JA,Ravelo ME,Mora-La Cruz E,Montiel-Nava C




Has Abstract


2011-02-01 00:00:00














  • Familial Creutzfeldt-Jakob disease associated with a point mutation at codon 210 of the prion protein gene.

    abstract::Creutzfeldt-Jakob disease (CJD), the most known human prion disease, is usually sporadic but approximately 15% of the cases are familial. To date, seven CJD cases with codon 210 mutation (GTT to ATT) have been reported in the literature. We describe a case of a 57 year-old woman who presented gait disturbances and rap...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Huang N,Marie SK,Kok F,Nitrini R

    更新日期:2001-12-01 00:00:00

  • Facial sensory symptoms in medullary infarcts.

    abstract:OBJECTIVE:To investigate the correlation between facial sensory abnormalities and lesional topography in eight patients with lateral medullary infarcts (LMIs). METHOD:We reviewed eight sequential cases of LMIs admitted to the Neurology Division of Hospital das Clínicas/São Paulo University between July, 2001 and Augus...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Conforto AB,Yamamoto FI,Leite Cda C,Scaff M,Marie SK

    更新日期:2005-12-01 00:00:00

  • [Diagnosis and treatment of the most frequent vestibular syndromes].

    abstract::The aims of this study were to identify the most common vestibular syndromes in a dizziness unit, and to observe their clinical aspects and response to treatment. Five hundred and fifteen patients were studied retrospectively in two institutions. Aspects of anamnesis, physical examination and the response to treatment...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Kanashiro AM,Pereira CB,Melo AC,Scaff M

    更新日期:2005-03-01 00:00:00

  • Syringohydromyelia associated to therapeutic procedures for severe forms of neurocysticercoses: case report.

    abstract::Syringohydromyelia is defined as a longitudinal dilatation of the central canal of the spinal cord with accumulated cerebrospinal fluid. This condition may cause neurologic deficits when the cavity enlarges and compresses the spinal cord. We present the case of a 33 years-old female with progressive paraparesis caused...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Honorato D,Borges W,Vargas AA,Ramina R

    更新日期:2004-09-01 00:00:00

  • [Expansive laminoplasty: an alternative for the treatment of cervical spondyloarthrosis].

    abstract::We describe the surgical technique of expansive cervical laminoplasty and analyse the results in 28 patients treated by this method for cervical spondylotic myelopathy with a minimum follow-up of six months. Twenty-four patients (86%) had clinical improvement according to the Nurick scale while three (10%) had no impr...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: de Andrade GC,da Silveira RL,Arantes AA Jr,Pinheiro N Jr,Rocha EM

    更新日期:2005-12-01 00:00:00

  • [Correlation between functional disability, age, and serum enzymes in neuromuscular diseases].

    abstract::We attempt to correlate the patient's disability and serum enzymes (creatinekinase, lactic dehydrogenase, aldolase, glutamic oxalacetic and glutamic piruvic transaminase) in several neuromuscular disorders using the Vignos and Archibald scale (V&A). In 806 cases we studied, serum enzyme levels and the V&A disability u...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Werneck LC

    更新日期:1995-03-01 00:00:00

  • [Surgical treatment of cerebral hemorrhage. Considerations on 11 cases].

    abstract::After brief comments about the angiographic findings on 298 consecutive cases of isquemic or hemorrhagic cerebral vascular strokes, cerebral angiography is emphasized as the main diagnostic method, owing to the variety of physiopathogenic and ethiologic factors involved in the genesis of this syndromes. The results of...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Pereira W,Godoy R,Ferreira C

    更新日期:1977-03-01 00:00:00

  • [Prognostic factors related to gunshot wounds to the spine in patients submitted to laminectomy].

    abstract::The spinal trauma related to civilian gunshot missile still remains a serious neurological event that carries a dismal prognosis almost in all cases. Its surgical indication also is a matter of discussion. Our goal is to identify the aspects that could influence the prognosis after surgery to this kind of lesions. We ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Flores LP,Nascimento Filho Jde S,Pereira Neto A,Suzuki K

    更新日期:1999-09-01 00:00:00

  • [Growth hormone deficiency after treatment of medulloblastoma with radiotherapy in childhood: case report].

    abstract::Craniospinal radiation therapy for treatment of brain tumors may result in growth hormone (GH) insufficiency with resultant linear growth retardation, one of the most common complications. We report the case of a 10-year-old boy presenting headache associated to vertigo, nausea and vomiting. A CT scan showed an homoge...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Goldberg TB,Rodrigues MA,Takata RT,Nogueira CR,Faleiros AT

    更新日期:2003-06-01 00:00:00

  • Schwartz-Jampel syndrome: report of five cases.

    abstract::We describe five patients with Schwartz-Jampel syndrome (SJS) examined at the outpatient service for neuromuscular disorders at our Institution from 1996 to 1999 with the objective of emphasizing the characteristic dysmorphic phenotype of SJS and its different clinical forms. Two cases presented SJS-type 1A, two had S...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Reed UC,Reimao R,Espindola AA,Kok F,Ferreira LG,Resende MB,Messias TC,Carvalho MS,Diament A,Scaff M,Marie SK

    更新日期:2002-09-01 00:00:00

  • Applicability of the CERAD neuropsychological battery to Brazilian elderly.

    abstract::There is a limited choice of psychometric tests for Portuguese speaking people which have been evaluated in well defined groups. A Portuguese version of CERAD neuropsychological battery was applied to a control group of healthy elderly (CG) (mean age 75.1 years/ education 7.9 years), 31 Alzheimer disease (AD) patients...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Bertolucci PH,Okamoto IH,Brucki SM,Siviero MO,Toniolo Neto J,Ramos LR

    更新日期:2001-09-01 00:00:00

  • [Adequate neuropsychological evaluation of dementia].

    abstract::The authors discuss the protocol of the Optimal Neuropsychological Evaluation of Dementias of Montreal and its possible application in Brazil. This protocol is important for evaluation in neuropsychological evolution of dementia of the Alzheimer type and for bringing to the fore distinct affected cognitive profiles as...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: de Brito-Marques PR,Joanette Y,Poissant A,Ska B

    更新日期:1995-03-01 00:00:00

  • [Neonatal Streptococcus pyogenes meningitis and sagittal sinus thrombosis: case report].

    abstract::We report a case of Streptococcus pyogenes meningitis in a 18 days year-old-girl with clinical course complicated by sagittal sinus thrombosis. Some aspects of the pathogenesis, treatment and follow-up of the disease are discussed. The world increase of serious streptococcal infections in the last 10 years, probably w...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Krebs VL,Chieffi LN,Jurfest ME,Ceccon R,Diniz EM,Feferbaum R,Takeuchi CA,Marques-Dias MJ,Carneiro JD,Vaz FA

    更新日期:1998-12-01 00:00:00

  • Headache among medical and psychology students.

    abstract:UNLABELLED:Headaches occur frequently and thus are a key component of sociocentric medical education. OBJECTIVE:To study headaches among students of medicine and psychology in a single university. METHOD:This was a questionnaire-based survey of a cohort of students of medicine and psychology. RESULTS:The overall lif...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Ferri-de-Barros JE,Alencar MJ,Berchielli LF,Castelhano Junior LC

    更新日期:2011-06-01 00:00:00

  • Exposure to pesticides and heterozygote genotype of GSTP1-Alw26I are associated to Parkinson's disease.

    abstract:OBJECTIVE:This study aimed to analyze the frequency of GSTP1-Alw26I polymorphism and to estimate its association with toxic substances in Parkinson's disease (PD). METHODS:A study group with 154 patients - subdivided into familial and sporadic PD groups - and 158 elderly individuals without the disease (control group)...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Longo GS,Pinhel MS,Sado CL,Gregório ML,Amorim GS,Florim GS,Mazeti CM,Martins DP,Oliveira FN,Tognola WA,Nakazone MA,Souza DR

    更新日期:2013-07-01 00:00:00

  • Acute bacterial meningitis caused by Streptococcus pneumoniae resistant to the antimicrobian agents and their serotypes.

    abstract::The main objectives of this study are to evaluate the resistance rates of Streptococcus pneumonia to penicillin G, ceftriaxone and vancomycin in patients with meningitis; to analyze possible risk factors to the antimicrobian resistance; to describe the serotypes detected and to suggest an initial empirical treatment f...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Rossoni AM,Dalla Costa LM,Berto DB,Farah SS,Gelain M,Brandileone MC,Ramos VH,Almeida SM

    更新日期:2008-09-01 00:00:00

  • Translation and validation into Brazilian version of the Scale of the Assessment and Rating of Ataxia (SARA).

    abstract:UNLABELLED:The hereditary ataxias comprise a very large spectrum of genetically determined neurodegenerative disorders with progressive ataxia as the prominent symptom. In order to measure the severity of cerebellar ataxia in an easier and more practical way, it was proposed a new scale: the Scale for the Assessment an...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Braga-Neto P,Godeiro-Junior C,Dutra LA,Pedroso JL,Barsottini OG

    更新日期:2010-04-01 00:00:00

  • [Reversible cerebral changes in hemolytic-uremic syndrome].

    abstract::The hemolytic-uremic syndrome is a pathology characterized by a triad consisting of acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia, with complications of the central nervous system arising in a considerable number of cases. Altered cranial computerized tomography examinations usually revea...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Santos AC,Siqueira Neto JI,Fabio SR

    更新日期:1995-06-01 00:00:00

  • [Neurolisteriosis in adults: report of six clinical cases].

    abstract:INTRODUCTION:Listeria monocytogenes shows a special attraction to infect the central nervous system and its meningeals coats. It affects newborn as well as elderly people, patients with deficiencies in their cellular immune systems, and healthy adults. It presents most commonly as an acute meningitis, although it can p...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Salamano R,Braselli A,Hoppe A,Monteghirfo R,Silva T

    更新日期:2005-12-01 00:00:00

  • Malignant transformation of pleomorphic xanthoastrocytoma: case report.

    abstract::We report a case of a pleomorphic xantoastrocytoma which manifested itself as a cystic isodense lesion in the right fronto-temporal lobe in a 26 year-old woman. It appeared as a soft yellow tumor with cystic cavities on surgery. Five months after this surgery, the patient was submitted to a new operation, which reveal...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: de Tella OI Jr,Herculano MA,Prandini MN,Stavale JN,Aguiar PH

    更新日期:2003-03-01 00:00:00

  • [Ectopic meningioma of the calvarium: report of a case].

    abstract::A case of calvarial meningeoma in a 42 year old female is reported. Arising from the inner table of the skull, it projected a extracranial mass without neurological simptomatology. The surgical procedure give good results. Some aspects of the literature and radiologics finds are commented. The infrequency of this path...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: de Moraes EC Jr,Haddad F,Maciel DR,Ribeiro JI,Wanderley EC,Passos EM

    更新日期:1982-06-01 00:00:00

  • Morphometric study of pre- and post-hatching nerve cell bodies of lumbar spinal ganglia of Gallus domesticus.

    abstract::A cytomorphometric study was performed in lumbar spinal ganglia neurons of Gallus domesticus on the 10th and 18th incubation days and 8th, 35th, 61st, and 120th post-hatching days. The absolute volume of nucleus and relative volume of cytoplasm were respectively estimated by the Bach caryometric method and by point-co...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: de Carvalho CA,da Silva CF,Silva Júnior BA,de Araujo MV

    更新日期:1983-09-01 00:00:00

  • [Language impairment in the early stages of Alzheimer's disease].

    abstract::Alzheimer disease (AD) is usually associated with cognitive, language and behavioral impairments, which can get more and more serious as the disease progresses. The aim of this study is to verify language disorders in the early stages of this disease. Twelve patients meeting criteria for problable AD were evaluated by...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Ortiz KZ,Bertolucci PH

    更新日期:2005-06-01 00:00:00

  • Teratogenic effects of lamotrigine on rat fetal brain: a morphometric study.

    abstract::A study of the teratogenic activity of an antiepileptic drug - lamotrigine - was carried out in the brain of fetuses of rats who had received the drug. The dosage levels studied corresponded to four times the median effective dose (ED50) in rats. The drug was administered during the organogenesis period. Rats were sac...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Marchi NS,Azoubel R,Tognola WA

    更新日期:2001-06-01 00:00:00

  • Botulinum toxin type A in the treatment of hemifacial spasm: an 11-year experience.

    abstract::In order to evaluate the long-term effect of botulinum toxin type A (BTX) in the treatment of hemifacial spasm (HFS), a retrospective analysis of patients treated at the Movement Disorders Unit of the Division of Neurology, Clinical Hospital, University of São Paulo, School of Medicine from 1993 to 2004 was made. A to...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Barbosa ER,Takada LT,Gonçalves LR,Costa RM,Silveira-Moriyama L,Chien HF

    更新日期:2010-08-01 00:00:00

  • Evaluation of upper endoscopic findings in patients with restless legs syndrome and gastric complaints.

    abstract:BACKGROUND:The effect of gastrointestinal system disorders on Restless Legs Syndrome/Willis-Ekbom disease (RLS/WED) has been previously demonstrated by using serological tests. However, this association has not been supported by histopathological studies so far. OBJECTIVE:To investigate the relationship between RLS/WE...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Çam M,Kutluana U

    更新日期:2020-04-01 00:00:00

  • Early stroke case-fatality rates in three hospital registries in the Northeast and Southeast of Brazil.

    abstract:UNLABELLED:Few studies have addressed early cerebrovascular lethality in Brazil. OBJECTIVE:To evaluate 10 and 28-day stroke case-fatality rates in three hospitals in three Brazilian cities. METHODS:We described the stroke registries in São Paulo, João Pessoa, and Natal. RESULTS:Out of a total of 962 first-ever event...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Fernandes TG,Goulart AC,Campos TF,Lucena NM,Freitas KL,Trevisan CM,Benseñor IM,Lotufo PA

    更新日期:2012-11-01 00:00:00

  • [Familial hemifacial spasm: report of 2 cases].

    abstract::The authors report the clinical and angiographical findings of two cases of familial hemifacial spasm. This is the fifth description in the literature and presents mother and daughter at the ages of 76 and 51 respectively, in whom the left side was affected. They underwent exams of angioresonance that showed dolichoba...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Barbosa ER,da Costa Mdo D,Staut CC,Bacheschi LA,Bittar MS

    更新日期:1998-03-01 00:00:00

  • Correlation of sleep macrostructure parameters and idiopathic epilepsies.

    abstract::Sleep and epilepsy share some common mechanisms. The objective of the present investigation was to study the macrostructure of sleep in patients with idiopathic epilepsies, focal and generalized, comparing these two groups to each other and to a control group of 12 individuals without epilepsy. A total of 35 polysomno...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Barreto JR,Fernandes RM,Sakamoto AC

    更新日期:2002-06-01 00:00:00

  • Computerized tomography findings in Fahr's syndrome.

    abstract::We analyzed computerized tomography (CT) findings in six patients with Fahr's syndrome. They presented calcifications in basal ganglia, dentate nucleus, subcortical region and semioval center, due to alteration in calcium metabolism or due to senile relative hypoxemic state. The image pattern was not strictly related ...

    journal_title:Arquivos de neuro-psiquiatria

    pub_type: 杂志文章


    authors: Faria AV,Pereira IC,Nanni L

    更新日期:2004-09-01 00:00:00