Stroke in patients with sickle cell disease: clinical and neurological aspects.

Abstract:

:The aim of this study was to characterize a group of patients (n=8) with sickle cell disease (SCD) and ischemic stroke concerning the clinical, neurological, imaging and progressive aspects. Data were collected from records and completed with an interview of patients and their parents. In this study there were 8 patients with ages ranging from 10 to 23 years old; SCD diagnosis was given between one and two years of age with clinical features of fatigue and anemia. The stroke was ischemic in all individuals and the first cerebrovascular event occurred before 6 years of age; 3 patients had recurrence of stroke despite prophylactic blood transfusion therapy and both cerebral hemispheres were affected in 4 patients. Clinical and neurological current features observed were: acute pain crises, sialorrhea, mouth breathing, motor, and neuropsychological impairments resulting from cortical-subcortical structure lesions.

journal_name

Arq Neuropsiquiatr

authors

Oliveira CC,Ciasca SM,Moura-Ribeiro MV

doi

10.1590/s0004-282x2008000100008

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

30-3

issue

1

eissn

0004-282X

issn

1678-4227

pii

S0004-282X2008000100008

journal_volume

66

pub_type

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