Midazolam: effects on amnesia and anxiety in children.

abstract：BACKGROUND:Alveolar overdistension and repetitive derecruitment-recruitment contribute to ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell activation due to VILI was assessable by positron emission tomography and (2) whether cell activation due to dynamic overdistension alon...

journal_title：Anesthesiology

authors： Musch G,Venegas JG,Bellani G,Winkler T,Schroeder T,Petersen B,Harris RS,Melo MF

更新日期：2007-04-01 00:00:00

abstract：:Neurophysiologic studies indicate that local anesthetic-induced seizures are generated in subcortical brain structures. The authors utilized a quantitative autoradiographic technique to measure cerebral metabolism during lidocaine-induced seizure activity in rats anesthetized with nitrous oxide. Local cerebral metabol...

journal_title：Anesthesiology

authors： Ingvar M,Shapiro HM

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Previous studies demonstrated that both edrophonium and neostigmine affect mivacurium's pharmacokinetics, thereby potentially affecting its recovery profile. However, those studies were not clinically relevant because mivacurium was still infused after the antagonists were given. In the present study, the au...

journal_title：Anesthesiology

authors： Szenohradszky J,Fogarty D,Kirkegaard-Nielsen H,Brown R,Sharma ML,Fisher DM

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Several beneficial effects of local anesthetics (LAs) were shown to be due to inhibition of G protein-coupled receptor signaling. Differences in exposure time might explain discrepancies in concentrations of LAs required to achieve these protective effects in vivo and in vitro (approximately 100-fold higher)...

journal_title：Anesthesiology

authors： Hollmann MW,Herroeder S,Kurz KS,Hoenemann CW,Struemper D,Hahnenkamp K,Durieux ME

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Multiport epidural catheters are popular; however, the reliability of the air test has not been evaluated with this catheter design. The authors determined the effectiveness of aspirating for blood and the air test in detecting intravascular multiorifice epidural catheters. METHODS:Three hundred women in la...

journal_title：Anesthesiology

authors： Leighton BL,Topkis WG,Gross JB,Arkoosh VA,Lee SH,Huffnagle HJ,Huffnagle SL

更新日期：2000-06-01 00:00:00

abstract：:Total lung capacity, vital capacity, residual volume, and functional residual capacity were determined by body plethysmography and the single-breath oxygen (SBO2) test was performed at 0, 5, and 11 cm H20 continuous positive airway pressure in healthy, awake, seated, spontaneously breathing subjects. Mean values for t...

journal_title：Anesthesiology

authors： Abboud N,Rehder K,Rodarte JR,Hyatt RE

更新日期：1975-02-01 00:00:00

abstract：:The sensitivity of the masseter, one of the muscles of the upper airway, to pancuronium was measured in ten adults undergoing elective surgery and compared with that of the adductor pollicis. During thiopental-nitrous oxide-enflurane (end-tidal concentration less than 0.25%) anesthesia, supramaximal nerve stimulation ...

journal_title：Anesthesiology

authors： Smith CE,Donati F,Bevan DR

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Whether coronary steal is induced by inhaled anesthetic agents remains controversial in part because multiple factors determine collateral blood flow. METHODS:We used an established model to determine how halothane, isoflurane, and desflurane affect the hemodynamic determinants of coronary collateral blood ...

journal_title：Anesthesiology

authors： Mignella R,Buffington CW

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Patient-controlled analgesia (PCA) with intravenous morphine and patient-controlled epidural analgesia (PCEA), using an opioid either alone or in combination with a local anesthetic, are two major advances in the management of pain after major surgery. However, these techniques have been evaluated poorly in ...

journal_title：Anesthesiology

authors： Mann C,Pouzeratte Y,Boccara G,Peccoux C,Vergne C,Brunat G,Domergue J,Millat B,Colson P

更新日期：2000-02-01 00:00:00

abstract：:The effects of the neodymium-yttrium aluminum garnet (Nd-YAG) laser on several commonly used endotracheal tubes were examined. Six different types of tubes were tested for flammability. Three tubes were clear, transparent polyvinylchloride with black lettering on the surface. One was yellow-green silicone rubber with ...

journal_title：Anesthesiology

authors： Geffin B,Shapshay SM,Bellack GS,Hobin K,Setzer SE

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Amitriptyline has been reported to be a more potent local anesthetic than bupivacaine. In keeping with the objective of identifying drugs for prolonged cutaneous analgesia, the authors compared the cutaneous analgesic effectiveness of amitriptyline and bupivacaine in rats. METHODS:Rats were subcutaneously i...

journal_title：Anesthesiology

authors： Khan MA,Gerner P,Kuo Wang G

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:General anesthetics may modify airway responsiveness. The authors investigated the effect of thiopental, propofol, and etomidate on airway smooth muscle. METHODS:Contraction experiments were done in human airway rings that were either normal or passively sensitized with asthmatic serum. The effect of propof...

journal_title：Anesthesiology

authors： Ouedraogo N,Roux E,Forestier F,Rossetti M,Savineau JP,Marthan R

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Results from previous studies on the effect of nitrous oxide (N2O) on the cerebral circulation are conflicting. Early reports claim N2O to have no effect whereas recent findings demonstrate a cerebral cortical vasodilatation during N2O inhalation, but the regional cerebral blood flow (CBF) in the subcortical...

journal_title：Anesthesiology

authors： Reinstrup P,Ryding E,Algotsson L,Berntman L,Uski T

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Neuroligin-1 (NL1) forms a complex with the presynaptic neurexin-1β (Nrx1b), regulating clustering of N-methyl-D-aspartate receptors with postsynaptic density-95 (PSD-95) to underlie learning-/memory-associated plasticity. Pain-related spinal neuroplasticity shares several common features with learning-/memo...

journal_title：Anesthesiology

authors： Lin TB,Lai CY,Hsieh MC,Jiang JL,Cheng JK,Chau YP,Ruan T,Chen GD,Peng HY

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Anesthetics administered to immature brains may cause histopathological changes and long-term behavioral abnormalities. The association between perinatal exposure to anesthetics during Cesarean delivery (CD) and development of learning disabilities (LD) was determined in a population-based birth cohort. MET...

journal_title：Anesthesiology

authors： Sprung J,Flick RP,Wilder RT,Katusic SK,Pike TL,Dingli M,Gleich SJ,Schroeder DR,Barbaresi WJ,Hanson AC,Warner DO

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) have been found to induce a delayed protective response called preconditioning to subsequent hypoxic/ischemic injury. VA preconditioning has been primarily studied in canine and rodent heart. A more genetically tractable model of VA preconditioning would be extremely useful. Here, ...

journal_title：Anesthesiology

authors： Jia B,Crowder CM

更新日期：2008-03-01 00:00:00

abstract：:Patients with mitral valve disease can develop pulmonary artery hypertension that persists after mitral valve replacement. In 1987, nitric oxide (NO) was reported to be an important factor accounting for the biologic activity of endothelium-derived relaxing factor. Inhaled NO was subsequently reported to be a selectiv...

journal_title：Anesthesiology

authors： Girard C,Lehot JJ,Pannetier JC,Filley S,Ffrench P,Estanove S

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:We evaluated whether spectral entropy (SpE) can measure the depth of hypnosis and the hypnotic drug effect in children during total intravenous anesthesia. METHODS:Sixty healthy children, aged 3-16 yr, were studied. Anesthesia was induced with an increasing target controlled infusion of propofol, and mainta...

journal_title：Anesthesiology

authors： Klockars JG,Hiller A,Münte S,van Gils MJ,Taivainen T

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Chloroprocaine has been associated with severe back pain after epidural anesthesia. Factors proposed to contribute to this problem are: 1) the preservative disodium ethylenediaminetetraacetic acid (EDTA), 2) large volumes of chloroprocaine, 3) low pH of chloroprocaine, and 4) local infiltration with chloropr...

journal_title：Anesthesiology

authors： Stevens RA,Urmey WF,Urquhart BL,Kao TC

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Spontaneous breaths during airway pressure release ventilation (APRV) have to overcome the resistance of the artificial airway. Automatic tube compensation provides ventilatory assistance by increasing airway pressure during inspiration and lowering airway pressure during expiration, thereby compensating for...

journal_title：Anesthesiology

authors： Wrigge H,Zinserling J,Hering R,Schwalfenberg N,Stüber F,von Spiegel T,Schroeder S,Hedenstierna G,Putensen C

更新日期：2001-08-01 00:00:00

abstract：:Oral transmucosal fentanyl citrate (OTFC) is a novel, noninvasive dosage form of fentanyl used to provide children and adults with sedation, anxiolysis, and analgesia. In order to determine the bioavailability and absorption of fentanyl from OTFC, 12 volunteers were given intravenous fentanyl citrate or OTFC 15 microg...

journal_title：Anesthesiology

authors： Streisand JB,Varvel JR,Stanski DR,Le Maire L,Ashburn MA,Hague BI,Tarver SD,Stanley TH

更新日期：1991-08-01 00:00:00

abstract：:The effect of halothane on the pressor responses to hypoxia (3% O2, 5% CO2, balance N2) and to Angiotensin II (Ang II) (0.2 microgram) has been compared in an in vitro perfused and ventilated rat lung preparation in the presence and absence of agents known to block the lipoxygenase (BW755C) and/or the cyclooxygenase (...

journal_title：Anesthesiology

authors： Marshall C,Kim SD,Marshall BE

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:During emergence from anesthesia, breathing 100% oxygen is frequently used to provide a safety margin toward hypoxemia in case an airway problem occurs. Oxygen breathing has been shown to cause pulmonary gas exchange disorders in healthy individuals. This study investigates how oxygen breathing during emerge...

journal_title：Anesthesiology

authors： Kleinsasser AT,Pircher I,Truebsbach S,Knotzer H,Loeckinger A,Treml B

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Mask ventilation is an essential element of airway management that has rarely been studied as the primary outcome. The authors sought to determine the incidence and predictors of difficult and impossible mask ventilation. METHODS:A four-point scale to grade difficulty in performing mask ventilation (MV) is ...

journal_title：Anesthesiology

authors： Kheterpal S,Han R,Tremper KK,Shanks A,Tait AR,O'Reilly M,Ludwig TA

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Postoperative cognitive dysfunction is common, but it remains unclear whether there are long-term adverse cognitive effects of surgery combined with anesthesia. The authors examined the association between exposure to surgery and level of cognitive functioning in a sample of 8,503 middle-aged and elderly twi...

journal_title：Anesthesiology

authors： Dokkedal U,Hansen TG,Rasmussen LS,Mengel-From J,Christensen K

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Postoperative visual loss after prone spine surgery is increasingly reported in association with ischemic optic neuropathy, but its etiology is unknown. METHODS:To describe the clinical characteristics of these patients, the authors analyzed a retrospectively collected series of 93 spine surgery cases volun...

journal_title：Anesthesiology

authors： Lee LA,Roth S,Posner KL,Cheney FW,Caplan RA,Newman NJ,Domino KB

更新日期：2006-10-01 00:00:00

abstract：:The hepatic effects of repeated anesthesia of phenobarbital-induced Fischer 344 rats with 1% halothane/14% oxygen were investigated, after anesthetics were administered at either 1-day or 5-day intervals. Urinary excretion of fluoride, a product of reductive halothane metabolism, was increased in the 24-h period follo...

journal_title：Anesthesiology

authors： Plummer JL,Hall PD,Jenner MA,Cousins MJ

更新日期：1987-09-01 00:00:00

abstract：:This study examined whether pain or stress can enhance the analgesic effects of spinally administered opiates. The experiments determined the effects of mechanically produced pain and of the stress of being restrained on the analgesic effects of 0.63 microgram of epidural sufentanil in rats using a tail-withdrawal pro...

journal_title：Anesthesiology

authors： Van den Hoogen RH,Bervoets K,Colpaert FC

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Acid instillation leads to direct lung and to secondary systemic organ injury, probably via activated macrophages and neutrophils. This study investigated the effects of neutrophil elastase on organ injury after unilateral lung acid instillation by administrating a specific neutrophil elastase inhibitor, ONO...

journal_title：Anesthesiology

authors： Kaneko K,Kudoh I,Hattori S,Yamada H,Ohara M,Wiener-Kronish J,Okumura F

更新日期：1997-09-01 00:00:00

abstract：:The authors determined whether they could predict accurately the solubility of anesthetics in aqueous solutions at 37 degrees C, knowing the osmolarity and the pH of the solution and the solute composition. The partition coefficients of the four volatile anesthetics, isoflurane, enflurane, halothane, and methoxyfluran...

journal_title：Anesthesiology

authors： Lerman J,Willis MM,Gregory GA,Eger EI 2nd

更新日期：1983-12-01 00:00:00