Pulmonary function after emergence on 100% oxygen in patients with chronic obstructive pulmonary disease: a randomized, controlled trial.

abstract：BACKGROUND:The memory-blocking properties of general anesthetics are of high clinical relevance and scientific interest. The inhalational anesthetic xenon antagonizes N-methyl-D-aspartate (NMDA) receptors. It is unknown if xenon affects long-term potentiation (LTP), a cellular correlate for memory formation. In hippoca...

journal_title：Anesthesiology

authors： Kratzer S,Mattusch C,Kochs E,Eder M,Haseneder R,Rammes G

更新日期：2012-03-01 00:00:00

abstract：:[This corrects the article on p. 1281 in vol. 121, issue 6, PMID: 25072223.]. ...

journal_title：Anesthesiology

authors：

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Transcranial motor-evoked potentials (TcMEPs) monitor spinal cord motor tract integrity. Using a swine model, the authors studied the effects of vasodilatory hypotension, hemorrhage, and various resuscitation efforts on TcMEP responses. METHODS:Twelve pigs were anesthetized with constant infusions of propof...

journal_title：Anesthesiology

authors： Lieberman JA,Feiner J,Lyon R,Rollins MD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with c...

journal_title：Anesthesiology

authors： Wang J,Goffer Y,Xu D,Tukey DS,Shamir DB,Eberle SE,Zou AH,Blanck TJ,Ziff EB

更新日期：2011-10-01 00:00:00

abstract：:I653 is a new volatile anesthetic structurally similar to enflurane and isoflurane. Since enflurane can induce convulsions, whereas isoflurane progressively depresses cortical electrical activity, the authors believed it important to assess the effect of I653 on the EEG (in both the "time" and "frequency" domain). The...

journal_title：Anesthesiology

authors： Rampil IJ,Weiskopf RB,Brown JG,Eger EI 2nd,Johnson BH,Holmes MA,Donegan JH

更新日期：1988-09-01 00:00:00

abstract：INTRODUCTION:The current investigation aimed to study the efficacy of hemostatic therapy guided either by conventional coagulation analyses or point-of-care (POC) testing in coagulopathic cardiac surgery patients. METHODS:Patients undergoing complex cardiac surgery were assessed for eligibility. Those patients in whom...

journal_title：Anesthesiology

authors： Weber CF,Görlinger K,Meininger D,Herrmann E,Bingold T,Moritz A,Cohn LH,Zacharowski K

更新日期：2012-09-01 00:00:00

abstract：:The effects of halothane (0.45 and 0.9 mM, equivalent to 0.7 and 1.5%, respectively), isoflurane (0.54 and 1.23 mM, equivalent to 0.9 and 2.0%, respectively) and enflurane (0.65 and 1.48 mM, equivalent to 1.2 and 2.5%, respectively) on macroscopic L- and T-type Ca2+ channel currents were compared in single canine card...

journal_title：Anesthesiology

authors： Eskinder H,Rusch NJ,Supan FD,Kampine JP,Bosnjak ZJ

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Although transesophageal echocardiography allows continuous intraoperative cardiac monitoring, the technique has been limited by the lack of a method for realtime, quantitative assessment of cardiac chamber size and systolic function. Automated border detection (ABD), based on an analysis of integrated backs...

journal_title：Anesthesiology

authors： Perrino AC Jr,Luther MA,O'Connor TZ,Cohen IS

更新日期：1995-08-01 00:00:00

abstract：:Hemodynamic changes during four anesthetic techniques were studied in 80 preterm neonates. Atropine, 0.02 mg/kg, and pancuronium, 0.1 mg/kg, were given intravenously to all patients, who were ventilated with oxygen and air. Each group of 20 patients then received 0.75% isoflurane, 0.5% halothane, 20 micrograms/kg fent...

journal_title：Anesthesiology

authors： Friesen RH,Henry DB

更新日期：1986-02-01 00:00:00

abstract：:Measurement of serum fentanyl and alfentanil concentrations by radioimmunoassay (RIA) may result in significant errors and high variability when the technique described in the available fentanyl and alfentanil RIA kits is used. The authors found a 29-94% overestimation of measured fentanyl and alfentanil serum levels ...

journal_title：Anesthesiology

authors： Schüttler J,White PF

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Global cerebral ischemia is associated with delayed neuronal death. Given the role of caspases in apoptosis, caspase inhibitors may provide neuronal protection after cardiac arrest. To this end, the authors generated a transgenic rat line expressing baculovirus p35, a broad-spectrum caspase inhibitor, in cen...

journal_title：Anesthesiology

authors： Vogel P,Putten Hv,Popp E,Krumnikl JJ,Teschendorf P,Galmbacher R,Kisielow M,Wiessner C,Schmitz A,Tomaselli KJ,Schmitz B,Martin E,Böttiger BW

更新日期：2003-07-01 00:00:00

abstract：:To study the effect of halothane on the coronary circulation, the circumflex diastolic coronary vascular resistance was measured in the working heart and total mean coronary resistance (TCR) in the isolated nonworking heart of the dog during administration of 100 per cent oxygen and during administration of 2--3 per c...

journal_title：Anesthesiology

authors： Domenech RJ,Macho P,Valdes J,Penna M

更新日期：1977-04-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Hypotension is a risk factor for adverse perioperative outcomes. Machine-learning methods allow large amounts of data for development of robust predictive analytics. The authors hypothesized that machine-learning methods can prov...

journal_title：Anesthesiology

authors： Kendale S,Kulkarni P,Rosenberg AD,Wang J

更新日期：2018-10-01 00:00:00

abstract：:The effects of anesthetic drugs on lipid order were evaluated by the fluorescence polarization of the probe molecule, 1,6-diphenyl-1,3,5-hexatriene (DPH) incorporated into vesicles of dimyristoylphosphatidylcholine (DMPC) and DMPC with 10 mol% ganglioside (GD1a). Anesthetics (enflurane, chloroform, diethylether, pento...

journal_title：Anesthesiology

authors： Harris RA,Groh GI

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:A recent model of acute incisional pain has been characterized that strongly parallels the postoperative period in patients experiencing evoked pain. In that setting, abundant literature has revealed antihypersensitive effects produced by intrathecally administered alpha2-adrenergic receptor agonists, such a...

journal_title：Anesthesiology

authors： Duflo F,Boselli E,Ryvlin P,Chassard D

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:In vitro, halothane appears to affect the role played by nitric oxide in the regulation of vascular tone and cardiac function. In vivo, the results of the interactions between halothane and the nitric oxide pathway remain controversial. The authors investigated the effects of halothane on the cardiac and reg...

journal_title：Anesthesiology

authors： Chelly JE,Doursout MF,Lechevalier T,Liang YY,Chelly F,Hartley C,Kilbourn RG

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Intrathecal clonidine reduces tactile allodynia in animal models of neuropathic pain, and this effect is blocked by atropine. However, the role of tonic spinal cholinergic activity and its interaction with alpha2-adrenergic systems in normal and neuropathic conditions and to different sensory methods has not...

journal_title：Anesthesiology

authors： Paqueron X,Conklin D,Eisenach JC

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Multiport epidural catheters are popular; however, the reliability of the air test has not been evaluated with this catheter design. The authors determined the effectiveness of aspirating for blood and the air test in detecting intravascular multiorifice epidural catheters. METHODS:Three hundred women in la...

journal_title：Anesthesiology

authors： Leighton BL,Topkis WG,Gross JB,Arkoosh VA,Lee SH,Huffnagle HJ,Huffnagle SL

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Inflammation is a key element in the pathophysiology of cerebral ischemia. This study investigated the role of N-Myc downstream-regulated gene-2 in nuclear transcription factor κB-mediated inflammation in ischemia models. METHODS:Mice (n = 6 to 12) with or without nuclear transcription factor κB inhibitor p...

journal_title：Anesthesiology

authors： Deng YL,Ma YL,Zhang ZL,Zhang LX,Guo H,Qin P,Hou YS,Gao ZJ,Hou WG

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Isoflurane has been said to be more ventilatory depressant than halothane. However, data for comparing the respiratory effects of halothane and isoflurane in humans are insufficient at this time. The aim of this study was to extend our understanding of the nature of the central, as opposed to peripheral, ven...

journal_title：Anesthesiology

authors： Canet J,Sanchis J,Zegrí A,Llorente C,Navajas D,Casan P

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The effects of thoracic epidural anesthesia (TEA) on myocardial repolarization and arrhythmogenicity are only incompletely understood. This is primarily because of the lack of appropriate experimental models. In most of the studies performed thus far, TEA was used in anesthetized animals. Baseline anesthesia...

journal_title：Anesthesiology

authors： Meissner A,Eckardt L,Kirchhof P,Weber T,Rolf N,Breithardt G,Van Aken H,Haverkamp W

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Xenon is a general anesthetic with neuroprotective properties. Xenon inhibition at the glycine-binding site of the N-Methyl-D-aspartate (NMDA) receptor mediates xenon neuroprotection against ischemic injury in vitro. Here we identify specific amino acids important for xenon binding to the NMDA receptor, with...

journal_title：Anesthesiology

authors： Armstrong SP,Banks PJ,McKitrick TJ,Geldart CH,Edge CJ,Babla R,Simillis C,Franks NP,Dickinson R

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Effects of volatile anesthetic agents on N-methyl-D-aspartate (NMDA) receptor-mediated excitatory synaptic transmission have not been well characterized. The authors compared effects produced by halothane and isoflurane on electrophysiologic properties of NMDA and non-NMDA receptor-mediated synaptic response...

journal_title：Anesthesiology

authors： Nishikawa K,MacIver MB

更新日期：2000-01-01 00:00:00

abstract：:Eighty-six patients undergoing coronary artery bypass graft (n = 63) or intracardiac (n = 23) surgery were randomly assigned with respect to the target value for PaCO2 during cardiopulmonary bypass. In 44 patients the target PaCO2 was 40 mmHg, measured at the standard electrode temperature of 37 degrees C, while in 42...

journal_title：Anesthesiology

authors： Bashein G,Townes BD,Nessly ML,Bledsoe SW,Hornbein TF,Davis KB,Goldstein DE,Coppel DB

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether halothane and isoflurane used during and after surgical injury attenuate subsequent hyperexcitability of spinal dorsal horn (SDH) neurons by preventing development of central sensitization. METHODS:Activity of a wide-dynamic-range neuron of the SDH was isolated...

journal_title：Anesthesiology

authors： Kawamata M,Narimatsu E,Kozuka Y,Takahashi T,Sugino S,Niiya T,Namiki A

更新日期：2005-01-01 00:00:00

abstract：:This study examined the interaction between thiopental and epinephrine in inducing ventricular arrhythmias in dogs. The arrhythmogenic threshold of epinephrine was determined during anesthesia with either halothane alone, thiopental alone, etomidate plus different doses of thiopental, or halothane plus different doses...

journal_title：Anesthesiology

authors： Hayashi Y,Sumikawa K,Yamatodani A,Tashiro C,Wada H,Yoshiya I

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Enflurane and isoflurane are structural isomers with different anesthetic potencies and side effects. It is not clear whether these differences are produced by differing occupancy of common protein binding sites or by occupancy of different sites, but the very similar molecular properties make the latter pos...

journal_title：Anesthesiology

authors： Liu R,Eckenhoff RG

更新日期：2005-04-01 00:00:00

abstract：:Isoflurane has a lesser ability than halothane to induce contracture in malignant hyperthermia (MH) muscle in vitro. This does not necessarily imply that isoflurane is not as potent an MH trigger as halothane in vivo. A hypothesis was tested that in vitro treatment with Bay K 8644, an activator of both the dihydropyri...

journal_title：Anesthesiology

authors： Adnet PJ,Krivosic-Horber RM,Adamantidis MM,Haudecoeur G,Reyford H,Imbenotte M

更新日期：1992-04-01 00:00:00

abstract：:The anesthetic requirements for sevoflurane, isoflurane, and halothane were determined in mongrel dogs. The MACs (minimum alveolar concentration) of sevoflurane, isoflurane, and halothane were 2.36 +/- 0.46% (n = 18), 1.39 +/- 0.25% (n = 10), and 0.89 +/- 0.20% (n = 12), respectively (mean +/- SD). In agreement with s...

journal_title：Anesthesiology

authors： Kazama T,Ikeda K

更新日期：1988-03-01 00:00:00

abstract：:The hemodynamic effects of prolonged mechanical ventilation with positive end-expiratory pressure (PEEP), with and without blood volume augmentation, were studied in 18 beagles anesthetized with halothane (0.7 per cent end-tidal). Addition of 12 cm H2O PEEP during mechanical ventilation in normavolemic dogs was associ...

journal_title：Anesthesiology

authors： Qvist J,Pontoppidan H,Wilson RS,Lowenstein E,Laver MB

更新日期：1975-01-01 00:00:00