Coronary vascular resistance during halothane anesthesia.

abstract：BACKGROUND:Dexmedetomidine is a sedative with modest analgesic efficacy, whereas remifentanil is an opioid analgesic with modest sedative potency. Synergy is often observed when sedative-hypnotics are combined with opioid analgesics in anesthetic practice. A three-phase crossover trial was conducted to study the pharma...

journal_title：Anesthesiology

authors： Weerink MAS,Barends CRM,Muskiet ERR,Reyntjens KMEM,Knotnerus FH,Oostra M,van Bocxlaer JFP,Struys MMRF,Colin PJ

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Obstetrics carries high medical liability risk. Maternal death and newborn death/brain damage were the most common complications in obstetric anesthesia malpractice claims before 1990. As the liability profile may have changed over the past two decades, the authors reviewed recent obstetric claims in the Ame...

journal_title：Anesthesiology

authors： Davies JM,Posner KL,Lee LA,Cheney FW,Domino KB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Pentobarbital decreases the gain of the baroreceptor reflex on the order of 50%, and this blunting is caused nearly entirely by decreasing cardioinhibitory parasympathetic activity. The most likely site of action of pentobarbital is the gamma-aminobutyric acid type A (GABA(A)) receptor. The authors tested wh...

journal_title：Anesthesiology

authors： Irnaten M,Walwyn WM,Wang J,Venkatesan P,Evans C,Chang KS,Andresen MC,Hales TG,Mendelowitz D

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Previously, the authors found that anesthetized diabetic dogs had increased cerebral blood flow (CBF) and oxygen consumption (CMRO2). These results may have been influenced by anesthesia or surgery. The aim of this study was to determine whether CBF and CMRO2 are increased in the awake or anesthetized state ...

journal_title：Anesthesiology

authors： Sieber FE,Brown PR,Wu Y,Koehler RC,Traystman RJ

更新日期：1993-11-01 00:00:00

abstract：:The treatment of venous air embolism by aspiration from central venous catheters is well established. However, some anesthesiologists prefer to use a pulmonary artery catheter to monitor patients undergoing a neurosurgical procedure in the sitting position. While offering certain advantages, pulmonary artery catheters...

journal_title：Anesthesiology

authors： Bowdle TA,Artru AA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Serious complications related to regional anesthesia have previously been described primarily in case reports and retrospective surveys. The authors prospectively evaluated a multicenter series of regional anesthetics, using preplanned criteria to measure the incidence and characteristics of associated serio...

journal_title：Anesthesiology

authors： Auroy Y,Narchi P,Messiah A,Litt L,Rouvier B,Samii K

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Clonidine produces analgesia after spinal injection by activating alpha2-adrenergic receptors. Recently, clonidine has been demonstrated to increase spinal release of norepinephrine (NE) in vivo, in contrast to that anticipated by classic presynaptic autoinhibition. The purpose of the current study was to de...

journal_title：Anesthesiology

authors： Li X,Zhao Z,Pan HL,Eisenach JC,Paqueron X

更新日期：2000-07-01 00:00:00

abstract：:Pharmacologic actions of CI-581, a chemical derivative of phencyclidine, were determined in 20 volunteers from a prison population. The results indicate that this drug is an effective analgesic and anesthetic agent in doses of 1.0 to 2.0 mg per kilogram. With intravenous administration the onset of action is within 1 ...

journal_title：Anesthesiology

authors： Domino EF

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:In children with a history of significant obstructive sleep apnea who undergo adenotonsillectomy, postsurgical administration of opiates has been alleged to be associated with an increased risk for respiratory complications, including respiratory depression. The authors hypothesize that this association is d...

journal_title：Anesthesiology

authors： Moss IR,Brown KA,Laferrière A

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Lidocaine inhalation attenuates histamine-induced bronchospasm while evoking airway anesthesia. Because this occurs at plasma concentrations much lower than those required for intravenous lidocaine to attenuate bronchial reactivity, this effect is likely related to topical airway anesthesia and presumably in...

journal_title：Anesthesiology

authors： Groeben H,Grosswendt T,Silvanus MT,Pavlakovic G,Peters J

更新日期：2001-03-01 00:00:00

abstract：:Nonsteroidal antiinflammatory drugs (NSAIDs) are commonly combined with intravenous morphine patient-controlled analgesia to relieve postoperative pain. NSAIDs have a documented 30-50% sparing effect on morphine consumption. However, most of the studies have not demonstrated a decrease in morphine adverse effects. A m...

journal_title：Anesthesiology

authors： Marret E,Kurdi O,Zufferey P,Bonnet F

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Effects of volatile anesthetic agents on N-methyl-D-aspartate (NMDA) receptor-mediated excitatory synaptic transmission have not been well characterized. The authors compared effects produced by halothane and isoflurane on electrophysiologic properties of NMDA and non-NMDA receptor-mediated synaptic response...

journal_title：Anesthesiology

authors： Nishikawa K,MacIver MB

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Although previous studies have proposed that anesthetics may influence signal transduction systems, their effects on the beta-adrenoceptor-mediated system have not been fully characterized in vascular smooth muscle. The aim of this study was to determine how halothane and isoflurane affect beta-adrenoceptor-...

journal_title：Anesthesiology

authors： Tanaka S,Tsuchida H

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Halogenated anesthetics potentiate the positive inotropic effects of alpha- and beta-adrenoceptor stimulations. Although diabetes mellitus induces significant myocardial abnormalities, the interaction of halogenated anesthetics and adrenoceptor stimulation in diabetic myocardium remains unknown. METHODS:Lef...

journal_title：Anesthesiology

authors： Amour J,David JS,Vivien B,Coriat P,Riou B

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Impaired cardiac repolarization, indicated by prolonged QT interval, may cause critical ventricular arrhythmias. Many anesthetics increase the QT interval by blockade of rapidly acting potassium rectifier channels. Although xenon does not affect these channels in isolated cardiomyocytes, the authors hypothes...

journal_title：Anesthesiology

authors： Neukirchen M,Schaefer MS,Kern C,Brett S,Werdehausen R,Rellecke P,Reyle-Hahn M,Kienbaum P

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:We examined the effects of different anesthetics on cerebral oxygenation and systemic hemodynamics in patients undergoing surgery in beach chair position (BCP). Jugular venous bulb oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (SctO2) were determined while patients were placed from...

journal_title：Anesthesiology

authors： Jeong H,Jeong S,Lim HJ,Lee J,Yoo KY

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Controversy exists regarding the effectiveness of propofol to prevent postoperative nausea and vomiting. This prospective, randomized, single-blinded study was designed to evaluate the antiemetic effectiveness of 0.5 mg/kg propofol when administered intravenously after sevoflurane- compared with desflurane-b...

journal_title：Anesthesiology

authors： Song D,Whitten CW,White PF,Yu SY,Zarate E

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Propofol is short-acting intravenous general anesthetics that reduces cardiovascular hemodynamics. The effects of propofol on intrinsic myocardial contractility, however, remain debatable. The aim of the current study was to test the hypothesis that inhibitory effects of propofol on left ventricular (LV) con...

journal_title：Anesthesiology

authors： Kuzumoto N,Kitagawa Y,Uemura K,Ueyama T,Yoshida K,Furuya H,Takaki M

更新日期：2004-10-01 00:00:00

abstract：:The effects of halothane on uptake and phosphorylation of uridine, and on cellular ATP content were studied in Tetrahymena pyriformis, a ciliate protozoan. Exposure to halothane inhibited the accumulation of 14C-uridine into the following acid-soluble intracellular pools: UTP, UDP, UMP, and an unidentified compound. H...

journal_title：Anesthesiology

authors： Conklin KA,Lau SS

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Intrathecal sufentanil (ITS) is frequently used to provide analgesia during labor. Decreases in blood pressure and sensory changes in this circumstance suggest that ITS may have a local anesthetic effect and thus cause a sympathectomy. To determine whether ITS given to laboring women causes a sympathectomy, ...

journal_title：Anesthesiology

authors： Riley ET,Walker D,Hamilton CL,Cohen SE

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Malignant hyperthermia is associated with mutations within the gene encoding the skeletal muscle ryanodine receptor, the calcium channel that releases Ca from sarcoplasmic reticulum stores triggering muscle contraction, and other metabolic activities. More than 200 variants have been identified in the ryanod...

journal_title：Anesthesiology

authors： Sato K,Pollock N,Stowell KM

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:There is substantial and growing literature on the actions of general anesthetics on a variety of neurotransmitter-gated ion channels, with the greatest attention being focused on inhibitory gamma-amino butyric acid type A receptors. In contrast, glutamate receptors, the most important class of fast excitato...

journal_title：Anesthesiology

authors： Plested AJ,Wildman SS,Lieb WR,Franks NP

更新日期：2004-02-01 00:00:00

abstract：:Chronic muscle disuse decreases the sensitivity of skeletal muscle to nondepolarizing relaxants, such as metocurine (MTC). In this study, the authors determined whether chronic conditioning would produce the opposite effect and increase the sensitivity of skeletal muscle to MTC. Five dogs were exercised by daily runni...

journal_title：Anesthesiology

authors： Gronert GA,White DA,Shafer SL,Matteo RS

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:The main cause of unsuccessful peripheral radial artery catheterization using traditional palpation is imprecisely locating the arterial center. The authors evaluated factors causing disparities between the arterial centers determined by palpation versus ultrasound. The authors applied them to create and tes...

journal_title：Anesthesiology

authors： Nakayama Y,Inagaki Y,Nakajima Y,Sessler DI,Mukai N,Ogawa S,Mizobe T,Sawa T

更新日期：2016-10-01 00:00:00

abstract：:Total lung capacity, vital capacity, residual volume, and functional residual capacity were determined by body plethysmography and the single-breath oxygen (SBO2) test was performed at 0, 5, and 11 cm H20 continuous positive airway pressure in healthy, awake, seated, spontaneously breathing subjects. Mean values for t...

journal_title：Anesthesiology

authors： Abboud N,Rehder K,Rodarte JR,Hyatt RE

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Interscalene block provides optimal shoulder surgery analgesia, but concerns over its associated risks have prompted the search for alternatives. Suprascapular block was recently proposed as an interscalene block alternative, but evidence of its comparative analgesic effect is conflicting. This meta-analysis...

journal_title：Anesthesiology

authors： Hussain N,Goldar G,Ragina N,Banfield L,Laffey JG,Abdallah FW

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Although neuromuscular blocking agents do not cross the blood-brain barrier, they may penetrate the central nervous system under particular circumstances and eventually cause neurotoxic consequences. METHODS:The effects of neuromuscular blocking agents on excitatory and inhibitory transmission in area CA1 o...

journal_title：Anesthesiology

authors： Chiodini FC,Tassonyi E,Fuchs-Buder T,Fathi M,Bertrand D,Muller D

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Whether the fetus can experience pain remains controversial. During the last half of pregnancy, the neuroanatomic connections for nociception are in place, and the human fetus mounts sizable stress responses to physical insults. Analgesia has been recommended for intrauterine procedures or late termination, ...

journal_title：Anesthesiology

authors： Fisk NM,Gitau R,Teixeira JM,Giannakoulopoulos X,Cameron AD,Glover VA

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Acid-sensing ion channel 3 (ASIC3) upregulation has been reported in dorsal root ganglion neurons after incision and contributes to postoperative nociception. This study hypothesized that upregulation of ASIC3 in incised tissues is induced by nerve growth factor through the phosphoinositide 3-kinase/protein ...

journal_title：Anesthesiology

authors： Li H,Li H,Cheng J,Liu X,Zhang Z,Wu C

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Animal models of ventilator-associated pneumonia (VAP) in primates, sheep, and pigs differ in the underlying pulmonary injury, etiology, bacterial inoculation methods, and time to onset. The most common ovine and porcine models do not reproduce the primary pathogenic mechanism of the disease, through the asp...

journal_title：Anesthesiology

authors： Li Bassi G,Rigol M,Marti JD,Saucedo L,Ranzani OT,Roca I,Cabanas M,Muñoz L,Giunta V,Luque N,Rinaudo M,Esperatti M,Fernandez-Barat L,Ferrer M,Vila J,Ramirez J,Torres A

更新日期：2014-05-01 00:00:00