Antiemetic activity of propofol after sevoflurane and desflurane anesthesia for outpatient laparoscopic cholecystectomy.

Abstract:

BACKGROUND:Controversy exists regarding the effectiveness of propofol to prevent postoperative nausea and vomiting. This prospective, randomized, single-blinded study was designed to evaluate the antiemetic effectiveness of 0.5 mg/kg propofol when administered intravenously after sevoflurane- compared with desflurane-based anesthesia. METHODS:Two hundred fifty female outpatients undergoing laparoscopic cholecystectomy were assigned randomly to one of four treatment groups. All patients were induced with intravenous doses of 2 mg midazolam, 2 microg/kg fentanyl, and 2 mg/kg propofol and maintained with either 1-4% sevoflurane (groups 1 and 2) or 2-8% desflurane (groups 3 and 4) in combination with 65% nitrous oxide in oxygen. At skin closure, patients in groups 1 and 3 were administered 5 ml intravenous saline, and patients in groups 2 and 4 were administered 0.5 mg/kg propofol intravenously. Recovery times were recorded from discontinuation of anesthesia to awakening, orientation, and readiness to be released home. Postoperative nausea and vomiting and requests for antiemetic rescue medication were evaluated during the first 24 h after surgery. RESULTS:Propofol, in an intravenous dose of 0.5 mg/kg, administered at the end of a sevoflurane-nitrous oxide or desflurane-nitrous oxide anesthetic prolonged the times to awakening and orientation by 40-80% and 25-30%, respectively. In group 2 (compared with groups 1, 3, and 4), the incidences of emesis (22% compared with 47%, 53%, and 47%) and requests for antiemetic rescue medication (19% compared with 42%, 50%, and 47%) within the first 6 h after surgery were significantly lower, and the time to home-readiness was significantly shorter in duration (216 +/- 50 min vs. 249 +/- 49 min, 260 +/- 88 min, and 254 +/- 72 min, respectively). CONCLUSIONS:A subhypnotic intravenous dose of propofol (0.5 mg/kg) administered at the end of outpatient laparoscopic cholecystectomy procedures was more effective in preventing postoperative nausea and vomiting after a sevoflurane-based (compared with a desflurane-based) anesthetic.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Song D,Whitten CW,White PF,Yu SY,Zarate E

doi

10.1097/00000542-199810000-00007

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

838-43

issue

4

eissn

0003-3022

issn

1528-1175

journal_volume

89

pub_type

临床试验,杂志文章,随机对照试验
  • Sonographic visualization and ultrasound-guided block of the third occipital nerve: prospective for a new method to diagnose C2-C3 zygapophysial joint pain.

    abstract:BACKGROUND:Chronic neck pain after whiplash injury is caused by cervical zygapophysial joints in 50% of patients. Diagnostic blocks of nerves supplying the joints are performed using fluoroscopy. The authors' hypothesis was that the third occipital nerve can be visualized and blocked with use of an ultrasound-guided te...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/00000542-200602000-00016

    authors: Eichenberger U,Greher M,Kapral S,Marhofer P,Wiest R,Remonda L,Bogduk N,Curatolo M

    更新日期:2006-02-01 00:00:00

  • Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension.

    abstract:WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Hypotension is a risk factor for adverse perioperative outcomes. Machine-learning methods allow large amounts of data for development of robust predictive analytics. The authors hypothesized that machine-learning methods can prov...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000002374

    authors: Kendale S,Kulkarni P,Rosenberg AD,Wang J

    更新日期:2018-10-01 00:00:00

  • Incidence and root cause analysis of wrong-site pain management procedures: a multicenter study.

    abstract:BACKGROUND:Medical errors exact an inordinate toll on healthcare costs. One of the most publicized and analyzed type of medical error is wrong-site surgery. Yet, despite the burgeoning number of procedures performed, no literature exists on wrong-site pain management injections. The purpose of this study was to estimat...

    journal_title:Anesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/ALN.0b013e3181cf892d

    authors: Cohen SP,Hayek SM,Datta S,Bajwa ZH,Larkin TM,Griffith S,Hobelmann G,Christo PJ,White R

    更新日期:2010-03-01 00:00:00

  • Malignant hyperthermia phenotype: hypotension induced by succinylcholine in susceptible swine.

    abstract:BACKGROUND:Succinylcholine causes immediate and severe arterial hypotension in swine with the malignant hyperthermia phenotype. The underlying mechanisms are unknown. METHODS:Malignant hyperthermia-susceptible (MHS; n = 10) and normal swine (n = 5) were anesthetized with thiopental. The following were monitored: elect...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200006000-00038

    authors: Sigg DC,Iaizzo PA

    更新日期:2000-06-01 00:00:00

  • Preoperative pain sensitivity and its correlation with postoperative pain and analgesic consumption: a qualitative systematic review.

    abstract::Pain perception to minor physical stimuli has been hypothesized to be related to subsequent pain ratings after surgery. The objective of this systematic review was to evaluate the correlation between preoperative pain sensitivity and postoperative pain intensity. After a literature search of MEDLINE, EMBASE, and meeti...

    journal_title:Anesthesiology

    pub_type: 杂志文章,评审

    doi:10.1097/ALN.0b013e3181f85ed2

    authors: Abrishami A,Chan J,Chung F,Wong J

    更新日期:2011-02-01 00:00:00

  • A comparison of tracheal tube tip designs on the passage of an endotracheal tube during oral fiberoptic intubation.

    abstract:BACKGROUND:The design of an endotracheal tube has been shown to influence the passage of the tube through the glottis during fiberoptic intubation. Difficulty in passing the endotracheal tube can occur if the aryepiglottic folds obstruct the passage of the bevel. The relevant aspects of endotracheal tube design include...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200105000-00007

    authors: Greer JR,Smith SP,Strang T

    更新日期:2001-05-01 00:00:00

  • Halothane-induced lipid peroxidation and glucose-6-phosphatase inactivation in microsomes under hypoxic conditions.

    abstract::Halothane-induced lipid peroxidation was studied in microsomes from phenobarbital-pretreated male rats at defined steady state oxygen partial pressures (PO2). At PO2 less than 10 mmHg on addition of halothane to NADPH-reduced microsomes, significant increases in malondialdehyde (MDA) formation, oxygen uptake, and conj...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198501000-00009

    authors: de Groot H,Noll T

    更新日期:1985-01-01 00:00:00

  • Factors affecting perioperative transfusion decisions in patients with coronary artery disease undergoing coronary artery bypass surgery.

    abstract:BACKGROUND:A high proportion of patients having cardiac bypass surgery receive erythrocyte transfusions. Decisions about when to transfuse patients having surgery for coronary artery disease may impact on erythrocyte utilization and patient morbidity and mortality. There are no published data about the factors that inf...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200607000-00008

    authors: Shehata N,Wilson K,Mazer CD,Tomlinson G,Streiner D,Hebert P,Naglie G

    更新日期:2006-07-01 00:00:00

  • Analgesic concentrations of lidocaine suppress tonic A-delta and C fiber discharges produced by acute injury.

    abstract::Intravenous lidocaine has been shown to relieve acute postoperative pain and chronic neuropathic pain. It is not known whether analgesia produced by 2-10 micrograms/ml plasma concentrations of lidocaine is due to an effect on peripheral-pain-transducing nerves or to central nervous system effects. The current study ex...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199105000-00020

    authors: Tanelian DL,MacIver MB

    更新日期:1991-05-01 00:00:00

  • Effect of renal failure and cirrhosis on the pharmacokinetics and neuromuscular effects of rapacuronium administered by bolus followed by infusion.

    abstract:BACKGROUND:Recent trials indicate that rapacuronium's pharmacokinetic characteristics are influenced by both renal failure and cirrhosis but the time course of a single bolus dose of 1.5 mg/kg is affected minimally. The authors reassessed these pharmacokinetic findings and examined the time course of the same bolus dos...

    journal_title:Anesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00000542-200012000-00007

    authors: Fisher DM,Dempsey GA,Atherton DP,Brown R,Abengochea A,Hunter JM

    更新日期:2000-12-01 00:00:00

  • Helium induces preconditioning in human endothelium in vivo.

    abstract:AIMS:Helium protects myocardium by inducing preconditioning in animals. We investigated whether human endothelium is preconditioned by helium inhalation in vivo. METHODS AND RESULTS:Forearm ischemia-reperfusion (I/R) in healthy volunteers (each group n = 10) was performed by inflating a blood pressure cuff for 20 min....

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e3182751300

    authors: Smit KF,Oei GT,Brevoord D,Stroes ES,Nieuwland R,Schlack WS,Hollmann MW,Weber NC,Preckel B

    更新日期:2013-01-01 00:00:00

  • Electrophysiologic characteristics of large neurons in dorsal root ganglia during development and after hind paw incision in the rat.

    abstract:BACKGROUND:Withdrawal thresholds in the paw are lower in younger animals, and incision further reduces these thresholds. The authors hypothesized that these differences result in part from changes in intrinsic electrophysiologic properties of large neurons. METHODS:Using isolated whole dorsal root ganglion, current cl...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e31817c1ab9

    authors: Ririe DG,Liu B,Clayton B,Tong C,Eisenach JC

    更新日期:2008-07-01 00:00:00

  • Preemptive intravenous morphine-6-glucuronide is ineffective for postoperative pain relief.

    abstract:BACKGROUND:Morphine-6-glucuronide (M-6-G), a major metabolite of morphine, is reported to be more potent than morphine when administered intrathecally; however, its efficiency remains under debate when administered intravenously. This study was designed to assess the analgesic efficiency of intravenous M-6-G for the tr...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200002000-00015

    authors: Motamed C,Mazoit X,Ghanouchi K,Guirimand F,Abhay K,Lieutaud T,Bensaid S,Fernandez C,Duvaldestin P

    更新日期:2000-02-01 00:00:00

  • The minimum alveolar concentration (MAC) and hemodynamic effects of halothane, isoflurane, and sevoflurane in newborn swine.

    abstract::To determine the minimum alveolar concentration (MAC) and hemodynamic responses to halothane, isoflurane, and sevoflurane in newborn swine, 36 fasting swine 4-10 days of age were anesthetized with one of the three volatile anesthetics in 100% oxygen. MAC was determined for each swine. Carotid artery and internal jugul...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199010000-00018

    authors: Lerman J,Oyston JP,Gallagher TM,Miyasaka K,Volgyesi GA,Burrows FA

    更新日期:1990-10-01 00:00:00

  • Intranasal nicotine for postoperative pain treatment.

    abstract:BACKGROUND:Despite pharmacological treatment, 70-80% of patients report moderate to severe pain after surgery. Because nicotine has been reported to have analgesic properties in animal and human volunteer studies, the authors assessed the analgesic efficacy of a single 3 mg dose of nicotine nasal spray administered bef...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200412000-00023

    authors: Flood P,Daniel D

    更新日期:2004-12-01 00:00:00

  • Thermoregulatory thresholds for vasoconstriction in patients anesthetized with various 1-minimum alveolar concentration combinations of xenon, nitrous oxide, and isoflurane.

    abstract:BACKGROUND:Nitrous oxide limits intraoperative hypothermia because the vasoconstriction threshold with nitrous oxide is higher than with equi-minimum alveolar concentrations of sevoflurane or isoflurane, presumably because of its stimulating actions on the sympathetic nervous system. Xenon, in contrast, does not cause ...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-199909000-00011

    authors: Goto T,Matsukawa T,Sessler DI,Uezono S,Ishiguro Y,Ozaki M,Morita S

    更新日期:1999-09-01 00:00:00

  • A randomized controlled trial of adaptive support ventilation mode to wean patients after fast-track cardiac valvular surgery.

    abstract:BACKGROUND:Adaptive support ventilation can speed weaning after coronary artery surgery compared with protocolized weaning using other modes. There are no data to support this mode of weaning after cardiac valvular surgery. Furthermore, control group weaning times have been long, suggesting that the results may reflect...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ALN.0000000000000589

    authors: Zhu F,Gomersall CD,Ng SK,Underwood MJ,Lee A

    更新日期:2015-04-01 00:00:00

  • Anesthesia for creation of a forearm fistula in patients with endstage renal failure.

    abstract::The effects of local infiltration anesthesia, brachial plexus blockade, isoflurane, or halothane anesthesia on blood flow through the brachial artery and through a newly created forearm arteriovenous fistula (AVF) were compared in 36 patients with endstage renal failure. Brachial artery blood flow was measured at two ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198906000-00005

    authors: Mouquet C,Bitker MO,Bailliart O,Rottembourg J,Clergue F,Montejo LS,Martineaud JP,Viars P

    更新日期:1989-06-01 00:00:00

  • A single subanesthetic dose of ketamine relieves depression-like behaviors induced by neuropathic pain in rats.

    abstract:BACKGROUND:Chronic pain is associated with depression. In rodents, pain is often assessed by sensory hypersensitivity, which does not sufficiently measure affective responses. Low-dose ketamine has been used to treat both pain and depression, but it is not clear whether ketamine can relieve depression associated with c...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e31822f16ae

    authors: Wang J,Goffer Y,Xu D,Tukey DS,Shamir DB,Eberle SE,Zou AH,Blanck TJ,Ziff EB

    更新日期:2011-10-01 00:00:00

  • Systemic antiinflammatory corticosteroid reduces mechanical pain behavior, sympathetic sprouting, and elevation of proinflammatory cytokines in a rat model of neuropathic pain.

    abstract:BACKGROUND:Chronic pain models are commonly defined as either nerve-injury or inflammation models, but recent work suggests inflammatory processes are important in nerve injury-induced pain. METHODS:In the rat spinal nerve ligation model, the authors examined effects of systemic corticosteroid triamcinolone acetonide ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/01.anes.0000278907.37774.8d

    authors: Li H,Xie W,Strong JA,Zhang JM

    更新日期:2007-09-01 00:00:00

  • Automated echocardiographic analysis. Examination of serial intraoperative measurements.

    abstract:BACKGROUND:Although transesophageal echocardiography allows continuous intraoperative cardiac monitoring, the technique has been limited by the lack of a method for realtime, quantitative assessment of cardiac chamber size and systolic function. Automated border detection (ABD), based on an analysis of integrated backs...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199508000-00008

    authors: Perrino AC Jr,Luther MA,O'Connor TZ,Cohen IS

    更新日期:1995-08-01 00:00:00

  • Effects of volatile and intravenous anesthesia on the alveolar and systemic inflammatory response in thoracic surgical patients.

    abstract:BACKGROUND:One-lung ventilation (OLV) results in alveolar proinflammatory effects, whereas their extent may depend on administration of anesthetic drugs. The current study evaluates the effects of different volatile anesthetics compared with an intravenous anesthetic and the relationship between pulmonary and systemic ...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/ALN.0b013e318214b9de

    authors: Schilling T,Kozian A,Senturk M,Huth C,Reinhold A,Hedenstierna G,Hachenberg T

    更新日期:2011-07-01 00:00:00

  • Epidural catheter reconnection. Safe and unsafe practice.

    abstract:BACKGROUND:An in vitro model of epidural catheter contamination was used to determine if disconnected catheters can be safely reconnected. METHODS:Epidural catheters were filled with brain-heart infusion (BHI) broth or preservative-free saline containing 5 micrograms/ml fentanyl. Escherichia coli, Pseudomonas aerugino...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199610000-00025

    authors: Langevin PB,Gravenstein N,Langevin SO,Gulig PA

    更新日期:1996-10-01 00:00:00

  • Intravenous lidocaine infusion facilitates acute rehabilitation after laparoscopic colectomy.

    abstract:BACKGROUND:Intravenous infusion of lidocaine decreases postoperative pain and speeds the return of bowel function. The authors therefore tested the hypothesis that perioperative lidocaine infusion facilitates acute rehabilitation protocol in patients undergoing laparoscopic colectomy. METHODS:Forty patients scheduled ...

    journal_title:Anesthesiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/00000542-200701000-00007

    authors: Kaba A,Laurent SR,Detroz BJ,Sessler DI,Durieux ME,Lamy ML,Joris JL

    更新日期:2007-01-01 00:00:00

  • Response to mivacurium in a patient compound heterozygous for a novel and a known silent mutation in the butyrylcholinesterase gene: genotyping by sequencing.

    abstract:BACKGROUND:Patients who are homozygous for the atypical mutation, compound heterozygous for atypical and silent mutations, or homozygous for silent mutations (SS) respond to mivacurium with extensively prolonged neuromuscular block. Although important, exact phenotyping of these patients is difficult. This article pres...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200109000-00010

    authors: Gätke MR,Ostergaard D,Bundgaard JR,Varin F,Viby-Mogensen J

    更新日期:2001-09-01 00:00:00

  • Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected.

    abstract:BACKGROUND:The mechanisms of action of general anesthetics are not completely understood. Many general anesthetics are reported to potentiate gamma-aminobutyric acid (GABAA) and glycine receptors in the central nervous system (CNS) and to inhibit the muscle-type nicotinic acetylcholine receptor (nAChR). The effects of ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199704000-00016

    authors: Flood P,Ramirez-Latorre J,Role L

    更新日期:1997-04-01 00:00:00

  • Differential behavioral effects of peripheral and systemic morphine and naloxone in a rat model of repeated acute inflammation.

    abstract:BACKGROUND:It has been reported that opioid antinociceptive effects are enhanced in animal models of inflammation, but it remains unclear whether this sensitization to morphine is related to predominant central or peripheral increased effects. METHODS:The authors compared the behavioral effects of intraplantar and int...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200105000-00027

    authors: Perrot S,Guilbaud G,Kayser V

    更新日期:2001-05-01 00:00:00

  • Estimating anesthesia and surgical procedure times from medicare anesthesia claims.

    abstract:BACKGROUND:Procedure times are important variables that often are included in studies of quality and efficiency. However, due to the need for costly chart review, most studies are limited to single-institution analyses. In this article, the authors describe how well the anesthesia claim from Medicare can estimate chart...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200702000-00024

    authors: Silber JH,Rosenbaum PR,Zhang X,Even-Shoshan O

    更新日期:2007-02-01 00:00:00

  • Dose-response curves for succinylcholine: single versus cumulative techniques.

    abstract::This study was performed to determine the potency of succinylcholine using the single-dose technique, and to test the ability of the cumulative dose technique for generating dose-response data. Thirty-eight adult patients received single doses (n = 18), cumulative doses (n = 10), or cumulative doses of succinylcholine...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:

    authors: Smith CE,Donati F,Bevan DR

    更新日期:1988-09-01 00:00:00

  • Individual probability of allogeneic erythrocyte transfusion in elective spine surgery: the predictive model of transfusion in spine surgery.

    abstract:BACKGROUND:The aim of this study was to generate a score based on preoperative characteristics and predictive of the individual probability of allogeneic erythrocyte transfusion in patients undergoing elective thoracolumbar spine surgery. METHODS:Two hundred thirty consecutive patients were retrospectively included ov...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e31819df9e0

    authors: Lenoir B,Merckx P,Paugam-Burtz C,Dauzac C,Agostini MM,Guigui P,Mantz J

    更新日期:2009-05-01 00:00:00