Preoperative pain sensitivity and its correlation with postoperative pain and analgesic consumption: a qualitative systematic review.

abstract：BACKGROUND:Ca2+ plays an important role in signal transduction and anesthetic mechanisms. To date, no one has observed a direct effect of volatile anesthetics on a Ca(2+)-binding protein. We therefore examined the effects of halothane and isoflurane on the Ca(2+)-binding properties of bovine brain calmodulin. METHODS:...

journal_title：Anesthesiology

authors： Levin A,Blanck TJ

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Airway pressure-release ventilation provides ventilation comparable to controlled mechanical ventilation (CMV), but with lower peak airway pressures and less dead-space ventilation. To obtain these advantages for patients administered general anesthesia, the authors (1) designed a mode similar to airway pres...

journal_title：Anesthesiology

authors： Bratzke E,Downs JB,Smith RA

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:It is increasingly important to evaluate patients' recovery after ambulatory surgery. The authors developed the Functional Recovery Index (FRI) to assess postdischarge functional recovery for ambulatory surgical patients. METHODS:The scale development involved four phases: item generation, item selection, r...

journal_title：Anesthesiology

authors： Wong J,Tong D,De Silva Y,Abrishami A,Chung F

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) have been found to induce a delayed protective response called preconditioning to subsequent hypoxic/ischemic injury. VA preconditioning has been primarily studied in canine and rodent heart. A more genetically tractable model of VA preconditioning would be extremely useful. Here, ...

journal_title：Anesthesiology

authors： Jia B,Crowder CM

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Prescription opioid abuse is a significant concern in treating chronic pain, yet few studies examine how neuropathic pain alters the abuse liability of commonly abused prescription opioids. METHODS:Normal and spinal nerve ligated (SNL) rats were implanted with electrodes into the left ventral tegmental area...

journal_title：Anesthesiology

authors： Ewan EE,Martin TJ

更新日期：2011-12-01 00:00:00

abstract：:This study was designed to assess the relationship between MAC and hypertension. To this purpose, MAC of halothane was determined in fully inbred spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY). Because MAC determination was performed in animals whose lungs were mechanically ventilated, the adequacy ...

journal_title：Anesthesiology

authors： Wouters P,Doursout MF,Merin RG,Chelly JE

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Administrators at hospitals with a fixed annual budget may want to focus surgical services on priority areas to ensure its community receives the best health services possible. However, many hospitals lack the detailed managerial accounting data needed to ensure that such a change does not increase operating...

journal_title：Anesthesiology

authors： Dexter F,Blake JT,Penning DH,Sloan B,Chung P,Lubarsky DA

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Clinical concentrations of volatile anesthetics significantly influence contractile response to the sympathetic neurotransmitter norepinephrine although its precise mechanisms remain unclarified. In this study, we investigated its possible alterations in diabetes, as well as its underlying mechanisms. METHO...

journal_title：Anesthesiology

authors： Yoshino J,Akata T,Shirozu K,Izumi K,Hoka S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The practice of chronic pain management has grown steadily in recent years. The purpose of this study was to identify and describe issues and trends in liability related to chronic pain management by anesthesiologists. METHODS:Data from 5,475 claims in the American Society of Anesthesiologists Closed Claims...

journal_title：Anesthesiology

authors： Fitzgibbon DR,Posner KL,Domino KB,Caplan RA,Lee LA,Cheney FW,American Society of Anesthesiologists.

更新日期：2004-01-01 00:00:00

abstract：:The antinociceptive interaction on the tail flick (TF) and hot plate (HP) tests between opioid analgesics and medetomidine after intravenous (iv) or intrathecal administration were examined by isobolographic analysis. Male Sprague-Dawley rats received fixed ratios of medetomidine to morphine, fentanyl, and meperidine ...

journal_title：Anesthesiology

authors： Ossipov MH,Harris S,Lloyd P,Messineo E,Lin BS,Bagley J

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to characterize cervical cord, root, and bony spine claims in the American Society of Anesthesiologists Closed Claims database to formulate hypotheses regarding mechanisms of injury. METHODS:All general anesthesia claims (1970-2007) in the Closed Claims database were searched to id...

journal_title：Anesthesiology

authors： Hindman BJ,Palecek JP,Posner KL,Traynelis VC,Lee LA,Sawin PD,Tredway TL,Todd MM,Domino KB

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:An in vitro model of epidural catheter contamination was used to determine if disconnected catheters can be safely reconnected. METHODS:Epidural catheters were filled with brain-heart infusion (BHI) broth or preservative-free saline containing 5 micrograms/ml fentanyl. Escherichia coli, Pseudomonas aerugino...

journal_title：Anesthesiology

authors： Langevin PB,Gravenstein N,Langevin SO,Gulig PA

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:The authors explored the database of the first International Study of Postoperative Cognitive Dysfunction study to specify the domains of cognitive function that were most vulnerable and to determine the pattern of deterioration in patients with preoperative cognitive impairment. METHODS:One thousand two hu...

journal_title：Anesthesiology

authors： Silverstein JH,Steinmetz J,Reichenberg A,Harvey PD,Rasmussen LS

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The mechanisms underlying depression-associated pain remain poorly understood. Using a mouse model of depression, the authors hypothesized that the central amygdala-periaqueductal gray circuitry is involved in pathologic nociception associated with depressive states. METHODS:The authors used chronic restrai...

journal_title：Anesthesiology

authors： Yin W,Mei L,Sun T,Wang Y,Li J,Chen C,Farzinpour Z,Mao Y,Tao W,Li J,Xie W,Zhang Z

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Massive release of central excitatory neurotransmitters is an important initial step in ischemic neuronal injury, and modification of this process may provide neuroprotection. We studied the protective effects of the voltage-dependent sodium channel antagonist riluzole and the N-methyl-d-aspartate receptor a...

journal_title：Anesthesiology

authors： Lips J,de Haan P,Bodewits P,Vanicky I,Dzoljic M,Jacobs MJ,Kalkman CJ

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:In the event of trauma, emergency reversal of anticoagulation therapy may be required. However, no specific reversal agents are routinely available for the direct oral anticoagulants such as dabigatran. The authors investigated four-factor prothrombin complex concentrate (PCC) for treating dabigatran-induced...

journal_title：Anesthesiology

authors： Honickel M,Braunschweig T,van Ryn J,Ten Cate H,Spronk HM,Rossaint R,Grottke O

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Povidone iodine (PI) solution is used commonly for skin disinfection before epidural and spinal anesthesia. Although there have been reports indicating the presence of microbial contaminants in PI solution, none have evaluated the prevalence of PI contamination. The aims of this study were to assess the freq...

journal_title：Anesthesiology

authors： Birnbach DJ,Stein DJ,Murray O,Thys DM,Sordillo EM

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Suboptimal tissue perfusion and oxygenation during surgery may be responsible for postoperative nausea and vomiting in some patients. This trial tested the hypothesis that muscular tissue oxygen saturation-guided intraoperative care reduces postoperative nausea and vomiting. METHODS:This multicenter, pragma...

journal_title：Anesthesiology

authors： Li G,Tian DD,Wang X,Feng X,Zhang W,Bao J,Wang DX,Ai YQ,Liu Y,Zhang M,Xu M,Mu DL,Zhao X,Dai F,Yang JJ,Che X,Yanez D,Guo X,Meng L,iMODIPONV Research Group.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Antioxidant anesthetics such as propofol (2,6-diisopropylphenol) directly inhibit lipid peroxidation via the generation of reactive oxygen species. Currently, there are no other studies regarding the direct effects of propofol medium chain triglyceride/long chain triglyceride (MCT/LCT) on reactive oxygen spe...

journal_title：Anesthesiology

authors： Kobayashi K,Yoshino F,Takahashi SS,Todoki K,Maehata Y,Komatsu T,Yoshida K,Lee MC

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively....

journal_title：Anesthesiology

authors： Klinger RY,James OG,Borges-Neto S,Bisanar T,Li YJ,Qi W,Berger M,Terrando N,Newman MF,Doraiswamy PM,Mathew JP,Alzheimer’s Disease Neuroimaging Initiative (ADNI) Study Group.,Neurologic Outcomes Research Group (NORG).

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:mu-Opioids administered spinally produce a potent, dose-dependent analgesic response in preclinical and clinical investigations. Side-effect profile of these compounds may be altered as a function of pharmacokinetics. The effects of intrathecal and intraperitoneal remifentanil, an esterase-metabolized mu opi...

journal_title：Anesthesiology

authors： Buerkle H,Yaksh TL

更新日期：1996-01-01 00:00:00

abstract：:Dexmedetomidine (DMED) is a highly selective centrally acting alpha 2-adrenergic agonist thought to provide significant sedation without appreciable ventilatory effects. This double-blind, placebo-controlled experiment evaluated four dose levels of DMED (0.25, 0.5, 1.0, and 2.0 micrograms/kg intravenously over 2 min) ...

journal_title：Anesthesiology

authors： Belleville JP,Ward DS,Bloor BC,Maze M

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Ketamine is often administered to patients in whom hemodynamic instability is suspected. This study was designed to investigate the effect and possible site of action of ketamine on baroreflex response in rats. The site focused upon was the N-methyl-D-aspartate (NMDA) receptor of the nucleus tractus solitari...

journal_title：Anesthesiology

authors： Ogawa A,Uemura M,Kataoka Y,Ol K,Inokuchi T

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Intraoperative remifentanil infusions have been associated with postoperative opioid-induced hyperalgesia and tolerance. Using a previously identified subpopulation of spinal neurons that displays an augmentation in N-methyl-D-aspartate (NMDA) receptor current after chronic morphine, investigations were unde...

journal_title：Anesthesiology

authors： Zhao M,Joo DT

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The memory-blocking properties of general anesthetics are of high clinical relevance and scientific interest. The inhalational anesthetic xenon antagonizes N-methyl-D-aspartate (NMDA) receptors. It is unknown if xenon affects long-term potentiation (LTP), a cellular correlate for memory formation. In hippoca...

journal_title：Anesthesiology

authors： Kratzer S,Mattusch C,Kochs E,Eder M,Haseneder R,Rammes G

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Propofol may produce amnesia by affecting encoding. The hypothesis that propofol weakens encoding was tested by measuring regional cerebral blood flow during verbal encoding. METHODS:Seventeen volunteer participants (12 men; aged 30.4 +/- 6.5 yr) had regional cerebral blood flow measured using H2O positron ...

journal_title：Anesthesiology

authors： Veselis RA,Pryor KO,Reinsel RA,Mehta M,Pan H,Johnson R Jr

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Alveolar overdistension and repetitive derecruitment-recruitment contribute to ventilator-induced lung injury (VILI). The authors investigated (1) whether inflammatory cell activation due to VILI was assessable by positron emission tomography and (2) whether cell activation due to dynamic overdistension alon...

journal_title：Anesthesiology

authors： Musch G,Venegas JG,Bellani G,Winkler T,Schroeder T,Petersen B,Harris RS,Melo MF

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The use of nicotinic agonists for analgesia is limited by their unacceptable side effects. Sazetidine-A is a new partial agonist nicotinic ligand that has very high selectivity for beta2-containing nicotinic acetylcholine receptors. It potently and selectively desensitizes alpha4beta2 nicotinic acetylcholine...

journal_title：Anesthesiology

authors： Cucchiaro G,Xiao Y,Gonzalez-Sulser A,Kellar KJ

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The Pediatric Perioperative Cardiac Arrest (POCA) Registry was formed in 1994 in an attempt to determine the clinical factors and outcomes associated with cardiac arrest in anesthetized children. METHODS:Institutions that provide anesthesia for children are voluntarily enrolled in the POCA Registry. A repre...

journal_title：Anesthesiology

authors： Morray JP,Geiduschek JM,Ramamoorthy C,Haberkern CM,Hackel A,Caplan RA,Domino KB,Posner K,Cheney FW

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Mechanical ventilation (MV) is a life-saving intervention in patients with acute respiratory failure. However, prolonged MV results in ventilator-induced diaphragm dysfunction (VIDD), a condition characterized by both diaphragm fiber atrophy and contractile dysfunction. Previous work has shown that calpain, ...

journal_title：Anesthesiology

authors： Smuder AJ,Nelson WB,Hudson MB,Kavazis AN,Powers SK

更新日期：2014-07-01 00:00:00