Povidone iodine and skin disinfection before initiation of epidural anesthesia.

Abstract:

BACKGROUND:Povidone iodine (PI) solution is used commonly for skin disinfection before epidural and spinal anesthesia. Although there have been reports indicating the presence of microbial contaminants in PI solution, none have evaluated the prevalence of PI contamination. The aims of this study were to assess the frequency of bacterial contamination of previously opened bottles of PI solution and to compare the effectiveness of new and previously opened bottles of PI solution for skin disinfection. METHODS:Twenty previously opened and ten previously unopened multiple-use bottles of PI solution were evaluated for microbial contamination. In addition, final swabs and PI solution used for skin disinfection in 80 patients undergoing elective epidural analgesia were evaluated. RESULTS:The inside of the bottle cap or the PI solution from 40% of the multiple-use PI bottles in use were contaminated. There was no growth from any previously unused PI bottles. Povidone iodine from newly opened bottles provided more effective skin decontamination than did solution from previously opened bottles. CONCLUSIONS:Multiple-use PI bottles in normal use may become contaminated by bacteria. In addition, PI solution from previously opened bottles was less effective than PI from previously unopened bottles. Based on these findings, if PI solution is chosen for skin antisepsis before initiation of epidural and spinal anesthesia, only single-use containers should be used.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Birnbach DJ,Stein DJ,Murray O,Thys DM,Sordillo EM

doi

10.1097/00000542-199803000-00017

subject

Has Abstract

pub_date

1998-03-01 00:00:00

pages

668-72

issue

3

eissn

0003-3022

issn

1528-1175

journal_volume

88

pub_type

杂志文章
  • Perioperative Outcomes and Management in Pediatric Complex Cranial Vault Reconstruction: A Multicenter Study from the Pediatric Craniofacial Collaborative Group.

    abstract:BACKGROUND:The Pediatric Craniofacial Collaborative Group established the Pediatric Craniofacial Surgery Perioperative Registry to elucidate practices and outcomes in children with craniosynostosis undergoing complex cranial vault reconstruction and inform quality improvement efforts. The aim of this study is to determ...

    journal_title:Anesthesiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/ALN.0000000000001481

    authors: Stricker PA,Goobie SM,Cladis FP,Haberkern CM,Meier PM,Reddy SK,Nguyen TT,Cai L,Polansky M,Szmuk P,Fiadjoe J,Soneru C,Falcon R,Petersen T,Kowalczyk-Derderian C,Dalesio N,Budac S,Groenewald N,Rubens D,Thompson D,Wat

    更新日期:2017-02-01 00:00:00

  • Preanesthetic train-of-four fade predicts the atracurium requirement of myasthenia gravis patients.

    abstract:BACKGROUND:The most sensitive diagnostic criterion of myasthenia gravis is a decrement in the muscular response to repetitive stimulation. The authors hypothesized that myasthenia gravis patients who show a train-of-four ratio (T4/T1) < 0.9 in the preanesthetic period will have increased sensitivity to nondepolarizing ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200008000-00011

    authors: Mann R,Blobner M,Jelen-Esselborn S,Busley R,Werner C

    更新日期:2000-08-01 00:00:00

  • Etymology of Letheon: Nineteenth-century Linguistic Effervescence.

    abstract::In late 1846, following his successful public demonstrations of surgical anesthesia, Boston dentist William T. G. Morton selected Letheon as the commercial name for the ether-based "preparation" he had used to produce insensibility to pain. We have not identified a first-hand account of the coinage of Letheon. Althoug...

    journal_title:Anesthesiology

    pub_type: 历史文章,杂志文章

    doi:10.1097/ALN.0000000000002969

    authors: Haridas RP,Gionfriddo M,Bause GS

    更新日期:2019-12-01 00:00:00

  • Thiopental treatment after global brain ischemia in pigtailed monkeys.

    abstract::The authors investigated the value of high-dose thiopental (TH) therapy after 16-min complete global brain ischemia (GBI) in three groups of pigtailed monkeys, using a neck cuff model of GBI with 96 h intensive care postischemia (PI). Control group (n18): Normotension was restored within 2 min PI; paralysis/controlled...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198402000-00002

    authors: Gisvold SE,Safar P,Hendrickx HH,Rao G,Moossy J,Alexander H

    更新日期:1984-02-01 00:00:00

  • Effects of halothane and isoflurane on hyperexcitability of spinal dorsal horn neurons after incision in the rat.

    abstract:BACKGROUND:The aim of this study was to determine whether halothane and isoflurane used during and after surgical injury attenuate subsequent hyperexcitability of spinal dorsal horn (SDH) neurons by preventing development of central sensitization. METHODS:Activity of a wide-dynamic-range neuron of the SDH was isolated...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200501000-00025

    authors: Kawamata M,Narimatsu E,Kozuka Y,Takahashi T,Sugino S,Niiya T,Namiki A

    更新日期:2005-01-01 00:00:00

  • Prolonged d-tubocurarine infusion and/or immobilization cause upregulation of acetylcholine receptors and hyperkalemia to succinylcholine in rats.

    abstract:BACKGROUND:Hyperkalemic cardiac arrest after the administration of succinylcholine (SCh) to critically ill intensive care patients has been attributed to changes in the acetylcholine receptors (AChRs) at the muscle membrane. The current study attempts to characterize the contributory roles of chronic administration of ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199602000-00017

    authors: Yanez P,Martyn JA

    更新日期:1996-02-01 00:00:00

  • Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome.

    abstract:BACKGROUND:The authors hypothesized that low tidal volume (VT) would minimize ventilator-induced lung injury regardless of the degree of mechanical power. The authors investigated the impact of power, obtained by different combinations of VT and respiratory rate (RR), on ventilator-induced lung injury in experimental m...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000002143

    authors: Santos RS,Maia LA,Oliveira MV,Santos CL,Moraes L,Pinto EF,Samary CDS,Machado JA,Carvalho AC,Fernandes MVS,Martins V,Capelozzi VL,Morales MM,Koch T,Gama de Abreu M,Pelosi P,Silva PL,Rocco PRM

    更新日期:2018-06-01 00:00:00

  • Flammability of endotracheal tubes during Nd-YAG laser application in the airway.

    abstract::The effects of the neodymium-yttrium aluminum garnet (Nd-YAG) laser on several commonly used endotracheal tubes were examined. Six different types of tubes were tested for flammability. Three tubes were clear, transparent polyvinylchloride with black lettering on the surface. One was yellow-green silicone rubber with ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198611000-00010

    authors: Geffin B,Shapshay SM,Bellack GS,Hobin K,Setzer SE

    更新日期:1986-11-01 00:00:00

  • Preanesthetic medication in children: a comparison of oral transmucosal fentanyl citrate versus placebo.

    abstract::Initial studies have suggested that oral transmucosal fentanyl citrate (OTFC) in a dose of 15-20 micrograms/kg may be a safe and effective preanesthetic medication in children and adults, but this has not been demonstrated in a randomized, double-blind fashion. The purpose of this study was to determine in a randomize...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Feld LH,Champeau MW,van Steennis CA,Scott JC

    更新日期:1989-09-01 00:00:00

  • Impaired systolic thickening associated with halothane in the presence of a coronary stenosis is mediated by changes in hemodynamics.

    abstract::Myocardial ischemia results when halothane is administered to animals with severe coronary stenosis. This study was done to separate the effect of halothane, per se, on myocardial ischemia from indirect cardiovascular effects, primarily hypotension, that might cause ischemia by altering the oxygen supply-demand balanc...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198605000-00014

    authors: Buffington CW

    更新日期:1986-05-01 00:00:00

  • Treatment of iron deficiency anemia in orthopedic surgery with intravenous iron: efficacy and limits: a prospective study.

    abstract:BACKGROUND:Preoperative anemia is frequent in patients undergoing orthopedic surgery. The purpose of this study was to assess the preoperative increase of hemoglobin in iron deficiency anemia patients treated with intravenous iron. METHODS:After obtaining written informed consent, 20 patients with iron deficiency anem...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/01.anes.0000291441.10704.82

    authors: Theusinger OM,Leyvraz PF,Schanz U,Seifert B,Spahn DR

    更新日期:2007-12-01 00:00:00

  • Prostacyclin regulates spinal nociceptive processing through cyclic adenosine monophosphate-induced translocation of glutamate receptors.

    abstract:BACKGROUND:Prostacyclin (PGI2) is known to be an important mediator of peripheral pain sensation (nociception) whereas little is known about its role in central sensitization. METHODS:The levels of the stable PGI2-metabolite 6-keto-prostaglandin F1α (6-keto-PGF1α) and of prostaglandin E2 (PGE2) were measured in the do...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e3182a76f74

    authors: Schuh CD,Brenneis C,Zhang DD,Angioni C,Schreiber Y,Ferreiros-Bouzas N,Pierre S,Henke M,Linke B,Nüsing R,Scholich K,Geisslinger G

    更新日期:2014-02-01 00:00:00

  • Quantitative Research Methods in Medical Education.

    abstract::There has been a dramatic growth of scholarly articles in medical education in recent years. Evaluating medical education research requires specific orientation to issues related to format and content. Our goal is to review the quantitative aspects of research in medical education so that clinicians may understand the...

    journal_title:Anesthesiology

    pub_type: 杂志文章,评审

    doi:10.1097/ALN.0000000000002727

    authors: Ratelle JT,Sawatsky AP,Beckman TJ

    更新日期:2019-07-01 00:00:00

  • Intravenous lidocaine inhibits visceral nociceptive reflexes and spinal neurons in the rat.

    abstract:BACKGROUND:Systemically administered local anesthetics and other sodium channel blockers produce analgesia in patients with hypersensitivity disorders. To assess whether these agents have a role in the treatment of visceral pain, the present study examined the effects of intravenous lidocaine on neuronal and reflex res...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200006000-00028

    authors: Ness TJ

    更新日期:2000-06-01 00:00:00

  • Myocardial hypercarbic acidosis reduces cardiac resuscitability.

    abstract:BACKGROUND:The severity of spontaneous myocardial hypercarbic acidosis during cardiac arrest previously has been predictive of the likelihood of restoring spontaneous circulation. The present study investigated whether hypercarbia itself impairs cardiac resuscitation. Since coronary perfusion pressure is the overriding...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199302000-00019

    authors: Maldonado FA,Weil MH,Tang W,Bisera J,Gazmuri RJ,Johnson B,D'Alessio A

    更新日期:1993-02-01 00:00:00

  • Insufflated halothane increases venous admixture less than nitroprusside in canine atelectasis.

    abstract::Although it generally is agreed that halothane is a pulmonary vasodilator, its effect on venous admixture and hypoxic pulmonary vasoconstriction are more controversial. The effects of 2.4% halothane on pulmonary vascular resistance and venous admixture were investigated in an isolated canine lobe made atelectatic. Hal...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199208000-00013

    authors: Johnson D,Hurst T,Mayers I

    更新日期:1992-08-01 00:00:00

  • Dose-response and plasma concentration-response relationships of pancuronium in man.

    abstract::The dose-response and plasma concentration-response relationships for pancuronium in man were studied during its intravenous administration to eight patients at a rate of 1.62 microgram/kg/min. The (log) dose-response relationships resulted in a sigmoid curve that was linear in its central range. At 20, 50 and 80 per ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-197908000-00004

    authors: Shanks CA,Somogyi AA,Triggs EJ

    更新日期:1979-08-01 00:00:00

  • Olprinone, a phosphodiesterase III inhibitor, reduces gut mucosal injury and portal endotoxin level during acute hypoxia in rabbits.

    abstract:BACKGROUND:Preservation of gut integrity has become a therapeutic goal to obviate bacterial translocation in the critically ill. The authors examined whether olprinone, a phosphodiesterase III inhibitor, protected functional and structural integrity of gut mucosa against acute progressive hypoxia. METHODS:Thirty-two a...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200306000-00016

    authors: Satoh T,Morisaki H,Ai K,Kosugi S,Yamamoto M,Serita R,Kotake Y,Takeda J

    更新日期:2003-06-01 00:00:00

  • Thermoregulatory thresholds for vasoconstriction in pediatric patients anesthetized with halothane or halothane and caudal bupivacaine.

    abstract::The thermoregulatory threshold for vasoconstriction has been studied in infants and children given isoflurane, but not in those given halothane anesthesia. More importantly, the effect of vasoconstriction on central temperature in pediatric patients remains unknown. Also unknown is the effect of caudal analgesia on va...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-199203000-00011

    authors: Bissonnette B,Sessler DI

    更新日期:1992-03-01 00:00:00

  • Optimal adrenergic support in septic shock due to peritonitis.

    abstract:BACKGROUND:The authors evaluated optimal adrenergic support using norepinephrine, dopamine, and dobutamine in a clinically relevant model of septic shock. METHODS:Twenty-eight mature, female, anesthetized sheep (weight, 30.5 +/- 3.6 kg) underwent cecal ligation and perforation and were randomized into four groups of s...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200304000-00015

    authors: Sun Q,Tu Z,Lobo S,Dimopoulos G,Nagy N,Rogiers P,De Backer D,Vincent JL

    更新日期:2003-04-01 00:00:00

  • A 1966 Anesthetic Administered by Robert D. Dripps, M.D., Demonstrated His Experimental Style of Clinical Care.

    abstract::Robert D. Dripps, M.D. (1911 to 1973), helped found academic anesthesiology. Newly reviewed teaching slides from the University of Pennsylvania (Philadelphia, Pennsylvania) contain six anesthesia records from 1965 to 1967 that involved Dripps. They illustrate the clinical philosophy he taught-to consider administratio...

    journal_title:Anesthesiology

    pub_type: 传,历史文章,杂志文章

    doi:10.1097/ALN.0000000000001109

    authors: Johnstone RE,Fleisher LA

    更新日期:2016-06-01 00:00:00

  • Developmental toxicity of nondepolarizing muscle relaxants in cultured rat embryos.

    abstract::Evidence of developmental toxicity of clinically used nondepolarizing muscle relaxants was sought in rat embryos grown in culture. Embryos were explanted at 8 AM on day 9 of gestation (presomite stage, plug day = day 0), and were cultured in rotating bottles with medium containing various concentrations of d-tubocurar...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199206000-00021

    authors: Fujinaga M,Baden JM,Mazze RI

    更新日期:1992-06-01 00:00:00

  • Neurologic evaluation of infant and adult rats before and after sciatic nerve blockade.

    abstract:BACKGROUND:Only limited data exist comparing differences in sensory function and responses to neural blockade in infant and adult rats. Therefore, the authors sought (1) to compare baseline thermal, proprioceptive, and postural responses in infant, adolescent, and adult rats; and (2) to compare the effects of sciatic n...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199704000-00026

    authors: Hu D,Hu R,Berde CB

    更新日期:1997-04-01 00:00:00

  • Adsorption characteristics of volatile anesthetics on activated carbons and performance of carbon canisters.

    abstract::The adsorption characteristics, such as the adsorption capacity, the nature of the mass transfer zone, and heats of adsorption, are important for evaluating the performances of carbon canisters for removal of waste anesthetic vapors. The adsorption capacities and the natures of the mass transfer zones were measured fo...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-197703000-00001

    authors: Kim BM,Sircar S

    更新日期:1977-03-01 00:00:00

  • Ulnar neuropathy. Incidence, outcome, and risk factors in sedated or anesthetized patients.

    abstract:BACKGROUND:Ulnar neuropathy is well-recognized as a potential complication of procedures performed on anesthetized patients. However, reported outcomes and risk factors for this problem are based on small series and anecdotes. METHODS:We retrospectively reviewed the perioperative courses of 1,129,692 consecutive patie...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:

    authors: Warner MA,Warner ME,Martin JT

    更新日期:1994-12-01 00:00:00

  • Relationship between cardiopulmonary bypass flow rate and cerebral embolization in dogs.

    abstract:BACKGROUND:Cerebral embolization is a primary cause of cardiac surgical neurologic morbidity. During cardiopulmonary bypass (CPB), there are well-defined periods of embolic risk. In theory, cerebral embolization might be reduced by an increase in pump flow during these periods. The purpose of this study was to determin...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199911000-00031

    authors: Sungurtekin H,Plöchl W,Cook DJ

    更新日期:1999-11-01 00:00:00

  • Supervised Machine-learning Predictive Analytics for Prediction of Postinduction Hypotension.

    abstract:WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Hypotension is a risk factor for adverse perioperative outcomes. Machine-learning methods allow large amounts of data for development of robust predictive analytics. The authors hypothesized that machine-learning methods can prov...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000002374

    authors: Kendale S,Kulkarni P,Rosenberg AD,Wang J

    更新日期:2018-10-01 00:00:00

  • Continuous interscalene analgesia with ropivacaine 2 mg/ml after major shoulder surgery.

    abstract:BACKGROUND:In this open, randomized study, the pharmacokinetics, clinical efficacy, and safety of a 48-h continuous interscalene infusion of 2 mg/ml ropivacaine for postoperative pain relief were investigated in patients undergoing open major shoulder surgery. METHODS:An initial interscalene block with 30 ml ropivacai...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200301000-00023

    authors: Ekatodramis G,Borgeat A,Huledal G,Jeppsson L,Westman L,Sjövall J

    更新日期:2003-01-01 00:00:00

  • Effects of halothane, propofol, and thiopental on peripheral airway reactivity.

    abstract:BACKGROUND:General anesthetics modify airway responsiveness by several mechanisms, including direct effects on airway smooth muscle and reductions in neural reflex activity. Halothane has been shown to reduce responsiveness through both of these mechanisms. The airway effects of barbiturates are controversial, and the ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199308000-00014

    authors: Mehr EH,Lindeman KS

    更新日期:1993-08-01 00:00:00

  • Automated echocardiographic analysis. Examination of serial intraoperative measurements.

    abstract:BACKGROUND:Although transesophageal echocardiography allows continuous intraoperative cardiac monitoring, the technique has been limited by the lack of a method for realtime, quantitative assessment of cardiac chamber size and systolic function. Automated border detection (ABD), based on an analysis of integrated backs...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199508000-00008

    authors: Perrino AC Jr,Luther MA,O'Connor TZ,Cohen IS

    更新日期:1995-08-01 00:00:00