Airway anesthesia alone does not explain attenuation of histamine-induced bronchospasm by local anesthetics: a comparison of lidocaine, ropivacaine, and dyclonine.

abstract：BACKGROUND:An in vitro model of epidural catheter contamination was used to determine if disconnected catheters can be safely reconnected. METHODS:Epidural catheters were filled with brain-heart infusion (BHI) broth or preservative-free saline containing 5 micrograms/ml fentanyl. Escherichia coli, Pseudomonas aerugino...

journal_title：Anesthesiology

authors： Langevin PB,Gravenstein N,Langevin SO,Gulig PA

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Although opioids remain the standard therapy for the treatment of postoperative pain, the prevalence of opioid misuse is rising. The extent to which opioid abuse or dependence affects readmission rates and healthcare utilization is not fully understood. It was hypothesized that surgical patients with a histo...

journal_title：Anesthesiology

authors： Gupta A,Nizamuddin J,Elmofty D,Nizamuddin SL,Tung A,Minhaj M,Mueller A,Apfelbaum J,Shahul S

更新日期：2018-05-01 00:00:00

abstract：:The effects of fentanyl or cardiovascular function, regional distribution of cardiac output, and the dose required for producing anesthesia were studied in ten previously catheterized, newborn lambs. In addition, the effects of fentanyl on cerebral blood flow and oxygen utilization were examined. Fentanyl in cumulativ...

journal_title：Anesthesiology

authors： Yaster M,Koehler RC,Traystman RJ

更新日期：1987-04-01 00:00:00

abstract：:Sevoflurane was submitted to phase-1 studies in man following extensive testing in animal species during maintenance, was administered with oxygen to produce one hour of anesthesia in six healthy adult male volunteers. Respiratory and cardiovascular functions, the electroencephalogram, arterial blood gases, blood sevo...

journal_title：Anesthesiology

authors： Holaday DA,Smith FR

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Autoregressive modeling with exogenous input of middle latency auditory evoked potentials (A-Line autoregressive index [AAI]) has been proposed for monitoring depth of anesthesia in adults. The aim of this study was to evaluate the performance of the AAI during induction of anesthesia with sevoflurane and re...

journal_title：Anesthesiology

authors： Weber F,Bein T,Hobbhahn J,Taeger K

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The pharmacokinetics and pharmacodynamics of succinylcholine were studied simultaneously in anesthetized patients to understand why the drug has a rapid onset and short duration of action. A quantitative model describing the concentration-effect relation of succinylcholine was proposed. The correlation betwe...

journal_title：Anesthesiology

authors： Roy JJ,Donati F,Boismenu D,Varin F

更新日期：2002-11-01 00:00:00

abstract：:Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia. By Audrey Shafer, Van A. Doze, Steven L. Shafer, and Paul F. White. Anesthesiology 1988; 69:348-56. Reprinted with permission.The pharmacokinetic and pharmacodynamic properties of propofol (Diprivan) were studied in 50 elective surg...

journal_title：Anesthesiology

authors： White PF

更新日期：2008-12-01 00:00:00

abstract：:Desflurane (formerly I-653) is a new inhalaticnal anesthetic with a promising pharmacokinetic profile that includes low solubility in blood and tissue, including fat. Since its lipid solubility is less than that of other volatile agents, it may have lower potency. Low solubility would be expected to increase the rate ...

journal_title：Anesthesiology

authors： Rampil IJ,Lockhart SH,Zwass MS,Peterson N,Yasuda N,Eger EI 2nd,Weiskopf RB,Damask MC

更新日期：1991-03-01 00:00:00

abstract：:The effect of hypocapnia on autoregulation of cerebral blood flow (CBF) and the lower limit of autoregulation (LLA) was determined in dogs anesthetized with nitrous oxide (66%) and halothane (0.2%, end-expired concentration). CBF and cerebral vascular resistance (CVR) were determined during both normocapnia and hypoca...

journal_title：Anesthesiology

authors： Artru AA,Katz RA,Colley PS

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Studies using transthoracic thermodilution have demonstrated increased extravascular lung water (EVLW) measurements attributed to progression of edema and flooding during sepsis and acute lung injury. The authors hypothesized that redistribution of pulmonary blood flow can cause increased apparent EVLW secon...

journal_title：Anesthesiology

authors： Easley RB,Mulreany DG,Lancaster CT,Custer JW,Fernandez-Bustamante A,Colantuoni E,Simon BA

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Anesthetic preconditioning (APC) with sevoflurane reduces myocardial ischemia-reperfusion injury. The authors tested whether two brief exposures to sevoflurane would lead to a better preconditioning state than would a single longer exposure and whether dual exposure to a lower (L) concentration of sevofluran...

journal_title：Anesthesiology

authors： Riess ML,Kevin LG,Camara AK,Heisner JS,Stowe DF

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Neural glial signaling in the spinal cord may underlie pain and sensitization after peripheral injury. The authors test the role of a glial activator, the chemokine (C-C motif) ligand 2 (CCL2), on mechanical hypersensitivity after plantar incision in a rat model of postoperative pain. METHODS:Twenty-four ho...

journal_title：Anesthesiology

authors： Peters CM,Eisenach JC

更新日期：2010-05-01 00:00:00

abstract：:Although it generally is agreed that halothane is a pulmonary vasodilator, its effect on venous admixture and hypoxic pulmonary vasoconstriction are more controversial. The effects of 2.4% halothane on pulmonary vascular resistance and venous admixture were investigated in an isolated canine lobe made atelectatic. Hal...

journal_title：Anesthesiology

authors： Johnson D,Hurst T,Mayers I

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:A decrease in radial artery blood pressure relative to central arterial blood pressure is commonly associated with the rewarming phase of cardiopulmonary bypass. Decreased hand vascular resistance has been suggested as a possible mechanism. Although decreased blood viscosity due to hemodilution may contribut...

journal_title：Anesthesiology

authors： Hynson JM,Sessler DI,Moayeri A,Katz JA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:The most sensitive diagnostic criterion of myasthenia gravis is a decrement in the muscular response to repetitive stimulation. The authors hypothesized that myasthenia gravis patients who show a train-of-four ratio (T4/T1) < 0.9 in the preanesthetic period will have increased sensitivity to nondepolarizing ...

journal_title：Anesthesiology

authors： Mann R,Blobner M,Jelen-Esselborn S,Busley R,Werner C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Macrophage recruitment into atherosclerotic plaques drives lesion progression, destabilization, and rupture. Chronic statin treatment reduces macrophage plaque content. Information on dynamics of macrophage recruitment would help assessing plaque vulnerability and guiding therapy. Techniques to image macroph...

journal_title：Anesthesiology

authors： Larmann J,Frenzel T,Schmitz M,Hahnenkamp A,Demmer P,Immenschuh S,Tietge UJ,Bremer C,Theilmeier G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The authors compare three techniques for insertion of the ProSeal laryngeal mask airway. METHODS:Two hundred forty healthy patients aged 18-80 yr were randomly allocated for ProSeal laryngeal mask airway insertion using the digital, introducer tool (IT), or gum elastic bougie (GEB)-guided techniques. The di...

journal_title：Anesthesiology

authors： Brimacombe J,Keller C,Judd DV

更新日期：2004-01-01 00:00:00

abstract：:The effects of continuous positive airway pressure (CPAP) on cardiovascular dynamics and pulmonary shunt (QS/QT) were investigated in 12 dogs before and during sodium nitroprusside infusion that decreased mean arterial blood pressure 40-50 per cent. Before nitroprusside infusion, 5 cm H2O CPAP significantly, P less th...

journal_title：Anesthesiology

authors： Hodges MR,Stanley TH,Johansen RK

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Drugs are routinely combined in anesthesia and pain management to obtain an enhancement of the desired effects. However, a parallel enhancement of the undesired effects might take place as well, resulting in a limited therapeutic usefulness. Therefore, when addressing the question of optimal drug combination...

journal_title：Anesthesiology

authors： Zanderigo E,Sartori V,Sveticic G,Bouillon T,Schumacher P,Morari M,Curatolo M

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:The authors developed a measure to determine whether maternal motivation to be present during induction (Motivation for Parental Presence during Induction of Anesthesia [MPPIA]) is related to children's anxiety during the induction process. METHODS:Mothers and children (aged 2-12 yr) undergoing outpatient, ...

journal_title：Anesthesiology

authors： Caldwell-Andrews AA,Kain ZN,Mayes LC,Kerns RD,Ng D

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Because ephedrine infusion (2 mg/min) does not adequately prevent spinal hypotension during cesarean delivery, the authors investigated whether adding phenylephrine would improve its efficacy. METHODS:Thirty-nine parturients with American Society of Anesthesiologists physical status I-II who were scheduled ...

journal_title：Anesthesiology

authors： Mercier FJ,Riley ET,Frederickson WL,Roger-Christoph S,Benhamou D,Cohen SE

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The authors determined the segmental effects of intracarotid verapamil in human subjects by using a novel method of measuring proximal and distal cerebrovascular resistance. Their hypothesis was that intracarotid verapamil, a calcium channel-blocking drug that augments cerebral blood flow and reverses arteri...

journal_title：Anesthesiology

authors： Joshi S,Meyers PM,Pile-Spellman J,Wang M,Sahlein DH

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:Since the effects of antiemetic doses of droperidol on the QT interval have not been previously studied, the authors designed a randomized, double-blind, placebo-controlled study to evaluate the intraoperative and postoperative effects of small-dose droperidol (0.625 and 1.25 mg intravenous) on the QT interv...

journal_title：Anesthesiology

authors： White PF,Song D,Abrao J,Klein KW,Navarette B

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The diagnosis of an acute malignant hyperthermia reaction by clinical criteria can be difficult because of the nonspecific nature and variable incidence of many of the clinical signs and laboratory findings. Development of a standardized means for estimating the qualitative likelihood of malignant hypertherm...

journal_title：Anesthesiology

authors： Larach MG,Localio AR,Allen GC,Denborough MA,Ellis FR,Gronert GA,Kaplan RF,Muldoon SM,Nelson TE,Ording H

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The authors investigated the impact of acute normovolemic hemodilution (ANH) on intrarenal oxygenation and its functional short-term consequences in pigs. METHODS:Renal microvascular oxygenation (µPO2) was measured in cortex, outer and inner medulla via three implanted optical fibers by oxygen-dependent que...

journal_title：Anesthesiology

authors： Konrad FM,Mik EG,Bodmer SI,Ates NB,Willems HF,Klingel K,de Geus HR,Stolker RJ,Johannes T

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Recent evidence indicates that vascular adenosine triphosphate-sensitive potassium (K(ATP)) channels in vascular smooth muscle cells are critical in the regulation of vascular tonus under both physiologic and pathophysiologic conditions. Studies of the interaction of volatile anesthetics with vascular K(ATP)...

journal_title：Anesthesiology

authors： Tanaka K,Kawano T,Nakamura A,Nazari H,Kawahito S,Oshita S,Takahashi A,Nakaya Y

更新日期：2007-05-01 00:00:00

abstract：:The occurrence of fasciculations following administration of agents is a well-known pharmacologic phenomenon. Using the cat soleus nerve-muscle preparation, intravenous neostigmine doses between 20-200 micrograms/kg evoked fasciculations in a dose-related manner. The data demonstrate that the fasciculations were the r...

journal_title：Anesthesiology

authors： Baker T,Stanec A

更新日期：1987-12-01 00:00:00

abstract：:Exposure of resting rat diaphragm for one hour in vitro to halothane (1-1.5, 2-2.5 and 4-4.5 per cent in oxygen) produced significant alterations of intracellular glucose disposition. Glycolysis (as measured by lactate production) increased, while glycogen formation was inhibited in a dose-related fashion. Net glucose...

journal_title：Anesthesiology

authors： Rosenberg H,Haugaard N,Haugaard ES

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Although transesophageal echocardiography allows continuous intraoperative cardiac monitoring, the technique has been limited by the lack of a method for realtime, quantitative assessment of cardiac chamber size and systolic function. Automated border detection (ABD), based on an analysis of integrated backs...

journal_title：Anesthesiology

authors： Perrino AC Jr,Luther MA,O'Connor TZ,Cohen IS

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:An initial pilot study of 300 sub-Tenon local anesthetic blocks (STBs) for intraocular surgery established the effectiveness and patient acceptability of the technique. Following this, a decision was made in 1995 to change from sharp needle techniques to STB for all eye surgeries performed during local anest...

journal_title：Anesthesiology

authors： Guise PA

更新日期：2003-04-01 00:00:00