Autoregulation of cerebral blood flow during normocapnia and hypocapnia in dogs.

abstract：BACKGROUND:The value of exercise electrocardiography in the prediction of perioperative cardiac risk has yet to be defined. This study was performed to determine the predictive value of exercise electrocardiography as compared with clinical parameters and resting electrocardiography. METHODS:A total of 204 patients at...

journal_title：Anesthesiology

authors： Gauss A,Röhm HJ,Schäuffelen A,Vogel T,Mohl U,Straehle A,Meierhenrich R,Georgieff M,Steinbach G,Schütz W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Cortical networks generate diverse patterns of rhythmic activity. Theta oscillations (4-12 Hz) are commonly observed during spatial learning and working memory tasks. The authors ask how etomidate, acting predominantly via gamma-aminobutyric acid type A (GABAA) receptors containing beta2 or beta3 subunits, a...

journal_title：Anesthesiology

authors： Drexler B,Roether CL,Jurd R,Rudolph U,Antkowiak B

更新日期：2005-02-01 00:00:00

abstract：:To determine whether anesthesiologists can manually detect significant changes in pulmonary compliance in neonates using an "educated hand," the authors tested whether clinicians could detect clamping of an endotracheal tube connecting a neonatal lung model to one of three anesthesia breathing circuits. The test lungs...

journal_title：Anesthesiology

authors： Spears RS Jr,Yeh A,Fisher DM,Zwass MS

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:A decrease in radial artery blood pressure relative to central arterial blood pressure is commonly associated with the rewarming phase of cardiopulmonary bypass. Decreased hand vascular resistance has been suggested as a possible mechanism. Although decreased blood viscosity due to hemodilution may contribut...

journal_title：Anesthesiology

authors： Hynson JM,Sessler DI,Moayeri A,Katz JA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Anecdotal reports suggest that the second trimester is the safest time to conduct a laparoscopic procedure on a pregnant patient, but this supposition has not been tested empirically. METHODS:Previously instrumented preterm sheep (total n = 8) at gestational day 90 (term, 145 days) were anesthetized and the...

journal_title：Anesthesiology

authors： Uemura K,McClaine RJ,de la Fuente SG,Manson RJ,Campbell KA,McClaine DJ,White WD,Stamler JS,Eubanks WS,Reynolds JD

更新日期：2004-12-01 00:00:00

abstract：:Using the technique of ventriculocisternal perfusion, resistance to reabsorption of cerebrospinal fluid (Ra) was calculated from determinations of the rate of reabsorption of cerebrospinal fluid (Va) at differing cerebrospinal fluid pressures in dogs. Ra was examined during prolonged anesthesia (5.0-6.0 h) with enflur...

journal_title：Anesthesiology

authors： Artru AA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:The hanging drop technique is used for identifying the cervical epidural space, using its negative pressure. However, it is doubtful whether the epidural space intrinsically exhibits a negative pressure. We designed this study to test the hypothesis that the cervical epidural pressure (CEP) is significantly ...

journal_title：Anesthesiology

authors： Moon JY,Lee PB,Nahm FS,Kim YC,Choi JB

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Cortical acetylcholine originates in the basal forebrain and is essential for maintaining normal cognition and arousal. Morphine impairs these cholinergically mediated cortical functions. The current study tested the hypothesis that morphine decreases prefrontal cortical acetylcholine release by acting at th...

journal_title：Anesthesiology

authors： Osman NI,Baghdoyan HA,Lydic R

更新日期：2005-10-01 00:00:00

abstract：:The effect of enflurane (2% and 4% inspired) on left ventricular (LV) function were examined in chronically instrumented dogs, both intact and after isolation of their hearts and lungs from the systemic circulation. Enflurane in the intact dogs increased heart rate (32 +/- 5% with 2% and 41 +/- 4% with 4%) and elicite...

journal_title：Anesthesiology

authors： Zimpfer M,Gilly H,Krösl P,Schlag G,Steinbereithner K

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:The abundance of a specific sodium channel subunit (SkM2) appeared to be altered in vitro in cell cultures from persons susceptible to malignant hyperthermia. This study sought to determine whether these findings are artifacts of cell culture or whether they may be relevant to malignant hyperthermia. METHOD...

journal_title：Anesthesiology

authors： Fletcher JE,Wieland SJ,Karan SM,Beech J,Rosenberg H

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Despite decreasing cardiac events, perioperative beta-blockade also increases perioperative stroke and mortality. Major bleeding and/or hypotension are independently associated with these outcomes. To investigate the hypothesis that beta-blockade limits the cardiac reserve to compensate for acute surgical an...

journal_title：Anesthesiology

authors： Beattie WS,Wijeysundera DN,Karkouti K,McCluskey S,Tait G,Mitsakakis N,Hare GM

更新日期：2010-01-01 00:00:00

abstract：:Intravenous lidocaine has been shown to relieve acute postoperative pain and chronic neuropathic pain. It is not known whether analgesia produced by 2-10 micrograms/ml plasma concentrations of lidocaine is due to an effect on peripheral-pain-transducing nerves or to central nervous system effects. The current study ex...

journal_title：Anesthesiology

authors： Tanelian DL,MacIver MB

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Available treatments for neuropathic pain have modest efficacy and significant adverse effects, including abuse potential. Because oxidative stress is a key mechanistic node for neuropathic pain, the authors focused on the master regulator of the antioxidant response-nuclear factor erythroid 2-related factor...

journal_title：Anesthesiology

authors： Li J,Ma J,Lacagnina MJ,Lorca S,Odem MA,Walters ET,Kavelaars A,Grace PM

更新日期：2020-02-01 00:00:00

abstract：:The authors studied the influence of locally administered isoflurane anesthesia on the pulmonary vascular response to regional alveolar hypoxia (hypoxic pulmonary vasoconstriction [HPV]) over a range of cardiac outputs (COs) in seven mechanically ventilated, closed-chest dogs. The right lung was ventilated with 100% O...

journal_title：Anesthesiology

authors： Domino KB,Borowec L,Alexander CM,Williams JJ,Chen L,Marshall C,Marshall BE

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:Volatile anesthetics (VAs) have been found to induce a delayed protective response called preconditioning to subsequent hypoxic/ischemic injury. VA preconditioning has been primarily studied in canine and rodent heart. A more genetically tractable model of VA preconditioning would be extremely useful. Here, ...

journal_title：Anesthesiology

authors： Jia B,Crowder CM

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Rapid assessment of hepatic function early after reperfusion of the liver graft is of great importance, because it may allow for prompt detection of incipient hepatic graft failure. The current study was undertaken to determine whether the continuous recording of neuromuscular transmission could be used as a...

journal_title：Anesthesiology

authors： Pittet JF,Morel DR,Mentha G,Schopfer C,Belenger J,Benakis A,Tassonyi E

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Elimination of daily-routine chest radiographs (CXRs) may influence chest computed tomography (CT) and ultrasound practice in critically ill patients. METHODS:This was a retrospective cohort study including all patients admitted to a university-affiliated intensive care unit during two consecutive periods o...

journal_title：Anesthesiology

authors： Kröner A,Binnekade JM,Graat ME,Vroom MB,Stoker J,Spronk PE,Schultz MJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Nitrous oxide causes an acute increase in plasma homocysteine that is more pronounced in patients with the methylenetetrahydrofolate reductase (MTHFR) C677T or A1298C gene variant. In this randomized controlled trial, the authors sought to determine whether patients carrying the MTHFR C677T or A1298C variant...

journal_title：Anesthesiology

authors： Nagele P,Brown F,Francis A,Scott MG,Gage BF,Miller JP,VINO Study Team.

更新日期：2013-07-01 00:00:00

abstract：:In experiments with rats, the authors compared potency ratios and slopes of dose-effect curves of isoflurane, halothane, and diethyl ether for three end points of anesthesia: loss of righting reflex (RR), abolition of purposeful movement (PM) response to painful stimuli, and abolition of heart rate (HR) response to pa...

journal_title：Anesthesiology

authors： Kissin I,Morgan PL,Smith LR

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:Obstetrics carries high medical liability risk. Maternal death and newborn death/brain damage were the most common complications in obstetric anesthesia malpractice claims before 1990. As the liability profile may have changed over the past two decades, the authors reviewed recent obstetric claims in the Ame...

journal_title：Anesthesiology

authors： Davies JM,Posner KL,Lee LA,Cheney FW,Domino KB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:(human ether-a-gogo related gene) encodes the cardiac rapidly activating delayed rectifier potassium currents (I(kr)), which play an important role in cardiac action potential repolarization. General anesthetics, like halothane, can prolong Q-T interval, suggesting that they act on myocellular repolarization...

journal_title：Anesthesiology

authors： Li J,Correa AM

更新日期：2002-10-01 00:00:00

abstract：:The effects of the neodymium-yttrium aluminum garnet (Nd-YAG) laser on several commonly used endotracheal tubes were examined. Six different types of tubes were tested for flammability. Three tubes were clear, transparent polyvinylchloride with black lettering on the surface. One was yellow-green silicone rubber with ...

journal_title：Anesthesiology

authors： Geffin B,Shapshay SM,Bellack GS,Hobin K,Setzer SE

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Dynorphin A in the spinal cord is considered to contribute to nociceptive stimuli. However, it has not yet been determined whether activation of the spinal dynorphinergic system under nociceptive stimuli plays a role in direct acceleration of the ascending nociceptive pathway. In this study, the authors inve...

journal_title：Anesthesiology

authors： Taketa Y,Niikura K,Kobayashi Y,Furuya M,Shimizu T,Narita M,Imai S,Kuzumaki N,Maitani Y,Yamazaki M,Inada E,Iseki M,Suzuki T,Narita M

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Although considerable evidence indicates neuronal Ca channels play significant roles in pain perception, their possible importance in hypersensitization after acute inflammation has not been investigated. METHODS:Using carrageenan for inducing hypersensitization, the authors investigated the analgesic effec...

journal_title：Anesthesiology

authors： Yokoyama K,Kurihara T,Makita K,Tanabe T

更新日期：2003-12-01 00:00:00

abstract：:The pharmacokinetics and protein binding of propofol were studied in ten patients with cirrhosis and in ten control patients undergoing elective surgery. All patients received 2.5 mg.kg-1 propofol as an intravenous bolus injection for the induction of anesthesia. Whole blood propofol concentrations were measured at in...

journal_title：Anesthesiology

authors： Servin F,Desmonts JM,Haberer JP,Cockshott ID,Plummer GF,Farinotti R

更新日期：1988-12-01 00:00:00

abstract：:The authors investigated the value of high-dose thiopental (TH) therapy after 16-min complete global brain ischemia (GBI) in three groups of pigtailed monkeys, using a neck cuff model of GBI with 96 h intensive care postischemia (PI). Control group (n18): Normotension was restored within 2 min PI; paralysis/controlled...

journal_title：Anesthesiology

authors： Gisvold SE,Safar P,Hendrickx HH,Rao G,Moossy J,Alexander H

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Studies have shown that permissive hypotension for uncontrolled hemorrhagic shock can result in good resuscitation outcome. The ideal target mean arterial pressure (MAP) and the tolerance time for permissive hypotension have not been determined. METHODS:To elucidate the ideal target MAP and tolerance time f...

journal_title：Anesthesiology

authors： Li T,Zhu Y,Hu Y,Li L,Diao Y,Tang J,Liu L

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Optimal analgesia for total knee arthroplasty remains challenging. Many modalities have been used, including peripheral nerve block, periarticular infiltration, and epidural analgesia. However, the relative efficacy of various modalities remains unknown. The authors aimed to quantify and rank order the effic...

journal_title：Anesthesiology

authors： Terkawi AS,Mavridis D,Sessler DI,Nunemaker MS,Doais KS,Terkawi RS,Terkawi YS,Petropoulou M,Nemergut EC

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:alpha 2 Agonists are powerful analgesics after spinal delivery. The current work characterizes the dose-dependent antinociception and effects upon respiratory function of dexmedetomidine after intrathecal, epidural, intravenous, and intracisternal delivery in chronically prepared dogs. METHODS:Dogs were pre...

journal_title：Anesthesiology

authors： Sabbe MB,Penning JP,Ozaki GT,Yaksh TL

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:The severity of spontaneous myocardial hypercarbic acidosis during cardiac arrest previously has been predictive of the likelihood of restoring spontaneous circulation. The present study investigated whether hypercarbia itself impairs cardiac resuscitation. Since coronary perfusion pressure is the overriding...

journal_title：Anesthesiology

authors： Maldonado FA,Weil MH,Tang W,Bisera J,Gazmuri RJ,Johnson B,D'Alessio A

更新日期：1993-02-01 00:00:00