Thermoregulatory and anesthetic-induced alterations in the differences among femoral, radial, and oscillometric blood pressures.


BACKGROUND:A decrease in radial artery blood pressure relative to central arterial blood pressure is commonly associated with the rewarming phase of cardiopulmonary bypass. Decreased hand vascular resistance has been suggested as a possible mechanism. Although decreased blood viscosity due to hemodilution may contribute to decreased hand vascular resistance, thermoregulatory vascular responses to core hyperthermia also may be important. METHODS:Seven healthy volunteers were studied. Volunteers first were cooled until thermoregulatory vasoconstriction was evident. Next, each was warmed until intense sweating developed. After a cool-down period, general anesthesia was induced with propofol and N2O. Femoral artery pressure (a surrogate for central arterial pressure) and radial artery and oscillometric (brachial artery) pressures were compared during each of six defined thermoregulatory and anesthetic study conditions. To determine the effect of hand vascular resistance on blood pressure differences, measurements were compared before and after occlusion of hand blood flow. Upper-extremity blood flow was evaluated by forearm and fingertip plethysmography and laser Doppler flowmetry. RESULTS:Forearm, fingertip, and cutaneous blood flow increased significantly during warming and were maximal during intense sweating. During thermoregulatory vasoconstriction, femoral, radial, and oscillometric mean blood pressures were similar. In contrast, radial artery mean pressure was 5 +/- 1 mmHg less than femoral artery mean pressure and 12 +/- 8 mmHg less than oscillometric mean pressure during intense sweating. Hand compression reduced these differences. The contour of the radial artery pressure waveform was dramatically altered by thermoregulatory and anesthetic conditions. Radial artery systolic pressure exceeded both femoral artery and oscillometric systolic pressures during vasoconstriction but was less than these during intense sweating. Hand compression reestablished the exaggerated radial artery systolic pressure during all study conditions. CONCLUSIONS:Thermoregulatory and anesthetic-induced alterations in upper-extremity blood flow substantially influence the relations among femoral artery, radial artery, and oscillometric blood pressure measurements.






Hynson JM,Sessler DI,Moayeri A,Katz JA




Has Abstract


1994-12-01 00:00:00












  • Cardiovascular responses to the induction of mild hypothermia in the presence of epidural anesthesia.

    abstract:BACKGROUND:The combining of epidural anesthesia with general anesthesia impairs central and peripheral thermoregulatory control and therefore is often accompanied by unintended intraoperative hypothermia. However, little is known about the cardiovascular response to hypothermia during combined epidural and general anes...


    pub_type: 杂志文章


    authors: Yoshida M,Shibata K,Itoh H,Yamamoto K

    更新日期:2001-04-01 00:00:00

  • Isoflurane and sevoflurane precondition against neutrophil-induced contractile dysfunction in isolated rat hearts.

    abstract:BACKGROUND:The authors tested the hypothesis that pretreatment with isoflurane or sevoflurane can protect the heart against neutrophil-induced contractile dysfunction. METHODS:Studies were conducted in buffer-perfused and paced isolated rat hearts. Left ventricular developed pressure served as an index of contractilit...


    pub_type: 杂志文章


    authors: Hu G,Salem MR,Crystal GJ

    更新日期:2004-03-01 00:00:00

  • Using process analysis to assess the impact of medical education on the delivery of pain services: a natural experiment.

    abstract:BACKGROUND:The medical, social, and economic effects of the teaching mission on delivery of care at an academic medical center (AMC) are not fully understood. When a free-standing private practice ambulatory clinic with no teaching mission was merged into an AMC, a natural experiment was created. The authors compared p...


    pub_type: 杂志文章


    authors: Williams KA,Chambers CG,Dada M,Hough D,Aron R,Ulatowski JA

    更新日期:2012-04-01 00:00:00

  • Differential effects of fentanyl and morphine on intracellular Ca2+ transients and contraction in rat ventricular myocytes.

    abstract:BACKGROUND:Our objective was to elucidate the direct effects of fentanyl and morphine on cardiac excitation-contraction coupling using individual, field-stimulated rat ventricular myocytes. METHODS:Freshly isolated myocytes were loaded with fura-2 and field stimulated (0.3 Hz) at 28 degrees C. Amplitude and timing of ...


    pub_type: 杂志文章


    authors: Kanaya N,Zakhary DR,Murray PA,Damron DS

    更新日期:1998-12-01 00:00:00

  • Growth cone collapsing effect of lidocaine on DRG neurons is partially reversed by several neurotrophic factors.

    abstract:BACKGROUND:Local anesthetics were suggested to have a potential for neurotoxicity in both clinical reports and laboratory experiments. Growing neurons have been shown to be susceptible to the toxic effects of local anesthetics in culture. These findings have generated the interest in factors that would rescue the neuro...


    pub_type: 杂志文章


    authors: Radwan IA,Saito S,Goto F

    更新日期:2002-09-01 00:00:00

  • Liposome encapsulation prolongs alfentanil spinal analgesia and alters systemic redistribution in the rat.

    abstract::The effect of liposome encapsulation on the analgesia produced by intrathecally administered alfentanil was examined in the rat. In rats prepared with chronic intrathecal catheters, alfentanil in doses of 1-50 micrograms was administered intrathecally in either saline or in multilamellar liposomes (dipalmitoylphosphat...


    pub_type: 杂志文章


    authors: Bernards CM,Luger TJ,Malmberg AB,Hill HF,Yaksh TL

    更新日期:1992-09-01 00:00:00

  • A Practical Training Program for Peripheral Radial Artery Catheterization in Adult Patients: A Prospective, Randomized Controlled Trial.

    abstract:BACKGROUND:The main cause of unsuccessful peripheral radial artery catheterization using traditional palpation is imprecisely locating the arterial center. The authors evaluated factors causing disparities between the arterial centers determined by palpation versus ultrasound. The authors applied them to create and tes...


    pub_type: 杂志文章,随机对照试验


    authors: Nakayama Y,Inagaki Y,Nakajima Y,Sessler DI,Mukai N,Ogawa S,Mizobe T,Sawa T

    更新日期:2016-10-01 00:00:00

  • Perioperative Outcomes and Management in Pediatric Complex Cranial Vault Reconstruction: A Multicenter Study from the Pediatric Craniofacial Collaborative Group.

    abstract:BACKGROUND:The Pediatric Craniofacial Collaborative Group established the Pediatric Craniofacial Surgery Perioperative Registry to elucidate practices and outcomes in children with craniosynostosis undergoing complex cranial vault reconstruction and inform quality improvement efforts. The aim of this study is to determ...


    pub_type: 杂志文章,多中心研究


    authors: Stricker PA,Goobie SM,Cladis FP,Haberkern CM,Meier PM,Reddy SK,Nguyen TT,Cai L,Polansky M,Szmuk P,Fiadjoe J,Soneru C,Falcon R,Petersen T,Kowalczyk-Derderian C,Dalesio N,Budac S,Groenewald N,Rubens D,Thompson D,Wat

    更新日期:2017-02-01 00:00:00

  • Trends in anesthesia-related death and brain damage: A closed claims analysis.

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    authors: Cheney FW,Posner KL,Lee LA,Caplan RA,Domino KB

    更新日期:2006-12-01 00:00:00

  • Lack of nephrotoxicity by 6% hydroxyethyl starch 130/0.4 during hip arthroplasty: a randomized controlled trial.

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    pub_type: 杂志文章,随机对照试验


    authors: Kancir AS,Pleckaitiene L,Hansen TB,Ekeløf NP,Pedersen EB

    更新日期:2014-11-01 00:00:00

  • Alteration by halothane of glucose and glycogen metabolism in rat skeletal muscle.

    abstract::Exposure of resting rat diaphragm for one hour in vitro to halothane (1-1.5, 2-2.5 and 4-4.5 per cent in oxygen) produced significant alterations of intracellular glucose disposition. Glycolysis (as measured by lactate production) increased, while glycogen formation was inhibited in a dose-related fashion. Net glucose...


    pub_type: 杂志文章


    authors: Rosenberg H,Haugaard N,Haugaard ES

    更新日期:1977-05-01 00:00:00

  • Preoperative electrocardiograms: patient factors predictive of abnormalities.

    abstract:BACKGROUND:Age is often the sole criterion for determining the need for preoperative electrocardiograms. However, screening electrocardiograms have not been shown to add value above clinical information. This study was designed to determine whether it is possible to target electrocardiograms ordering to patients most l...


    pub_type: 杂志文章,随机对照试验


    authors: Correll DJ,Hepner DL,Chang C,Tsen L,Hevelone ND,Bader AM

    更新日期:2009-06-01 00:00:00

  • Comparison of bispectral index and composite auditory evoked potential index for monitoring depth of hypnosis in children.

    abstract:BACKGROUND:In pediatric patients, the Bispectral Index (BIS), derived from the electroencephalogram, and the composite A-Line autoregressive index (cAAI), derived from auditory evoked potentials and the electroencephalogram, have been used as measurements of depth of hypnosis during anesthesia. The performance and reli...


    pub_type: 杂志文章


    authors: Blussé van Oud-Alblas HJ,Peters JW,de Leeuw TG,Tibboel D,Klein J,Weber F

    更新日期:2008-05-01 00:00:00

  • Extracellular histones play an inflammatory role in acid aspiration-induced acute respiratory distress syndrome.

    abstract:BACKGROUND:Systemic inflammation is a key feature in acid aspiration-induced acute respiratory distress syndrome (ARDS), but the factors that trigger inflammation are unclear. The authors hypothesize that extracellular histones, a newly identified inflammatory mediator, play important roles in the pathogenesis of ARDS....


    pub_type: 杂志文章


    authors: Zhang Y,Wen Z,Guan L,Jiang P,Gu T,Zhao J,Lv X,Wen T

    更新日期:2015-01-01 00:00:00

  • Effect of 1.5% Topical Diclofenac on Clinical Neuropathic Pain.

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    pub_type: 杂志文章,随机对照试验


    authors: Ahmed SU,Zhang Y,Chen L,Cohen A,St Hillary K,Vo T,Houghton M,Mao J

    更新日期:2015-07-01 00:00:00

  • Effects of exogenous surfactant on acute lung injury induced by intratracheal instillation of infant formula or human breast milk in rabbits.

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    authors: Nishina K,Mikawa K,Takao Y,Maekawa N,Obara H

    更新日期:1999-07-01 00:00:00

  • Sonographic visualization and ultrasound-guided block of the third occipital nerve: prospective for a new method to diagnose C2-C3 zygapophysial joint pain.

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    pub_type: 杂志文章,随机对照试验


    authors: Eichenberger U,Greher M,Kapral S,Marhofer P,Wiest R,Remonda L,Bogduk N,Curatolo M

    更新日期:2006-02-01 00:00:00

  • Exercise produces sensitivity to metocurine.

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    pub_type: 杂志文章


    authors: Gronert GA,White DA,Shafer SL,Matteo RS

    更新日期:1989-06-01 00:00:00

  • Comparison of the costs and recovery profiles of three anesthetic techniques for ambulatory anorectal surgery.

    abstract:BACKGROUND:Given the current practice environment, it is important to determine the anesthetic technique with the highest patient acceptance and lowest associated costs. The authors compared three commonly used anesthetic techniques for anorectal procedures in the ambulatory setting. METHODS:Ninety-three consenting ad...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Li S,Coloma M,White PF,Watcha MF,Chiu JW,Li H,Huber PJ Jr

    更新日期:2000-11-01 00:00:00

  • Thiopental alters contraction, intracellular Ca2+, and pH in rat ventricular myocytes.

    abstract:BACKGROUND:Myocardial contractility is regulated by intracellular concentration of free Ca2+ ([Ca2'],) and myofilament Ca2+ sensitivity. The objective of this study was to elucidate the direct effects of thiopental on cardiac excitation-contraction coupling using individual, field-stimulated ventricular myocytes. METH...


    pub_type: 杂志文章


    authors: Kanaya N,Zakhary DR,Murray PA,Damron DS

    更新日期:1998-07-01 00:00:00

  • Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study.

    abstract:BACKGROUND:Patients with initial mild acute respiratory distress syndrome are often underrecognized and mistakenly considered to have low disease severity and favorable outcomes. They represent a relatively poorly characterized population that was only classified as having acute respiratory distress syndrome in the mos...


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    authors: Pham T,Serpa Neto A,Pelosi P,Laffey JG,De Haro C,Lorente JA,Bellani G,Fan E,Brochard LJ,Pesenti A,Schultz MJ,Artigas A,LUNG SAFE Investigators* and the European Society of Intensive Care Medicine Trials Group.

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  • Autologous platelet-rich plasma does not reduce transfusion of homologous blood products in patients undergoing repeat valvular surgery.

    abstract:BACKGROUND:Patients undergoing cardiac surgery employing cardiopulmonary bypass frequently require transfusion of homologous blood products and, therefore, are exposed to the risk of transfusions. Autologous platelet-rich plasma administration may reduce homologous transfusion and attendant risks. METHODS:In a blinded...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Ereth MH,Oliver WC Jr,Beynen FM,Mullany CJ,Orszulak TA,Santrach PJ,Ilstrup DM,Weaver AL,Williamson KR

    更新日期:1993-09-01 00:00:00

  • Thoracic epidural anesthesia increases mucosal perfusion in ileum of rats.

    abstract:BACKGROUND:Previous studies reported that thoracic epidural anesthesia (TEA) protected against a decrease in gastric intramucosal pH, suggesting that TEA increased gut mucosal perfusion. The current study examines the effects of TEA on ileal mucosa using intravital microscopy in anesthetized rats. METHODS:Nineteen rat...


    pub_type: 杂志文章


    authors: Sielenkämper AW,Eicker K,Van Aken H

    更新日期:2000-09-01 00:00:00

  • Effects of halothane on sarcoplasmic reticulum calcium release channels in porcine airway smooth muscle cells.

    abstract:BACKGROUND:Volatile anesthetics relax airway smooth muscle (ASM) by altering intracellular Ca2+ concentration ([Ca2+]i). The authors hypothesized that relaxation is produced by decreasing sarcoplasmic reticulum Ca2+ content via increased Ca2+ "leak" through both inositol trisphosphate (IP3) and ryanodine receptor chann...


    pub_type: 杂志文章


    authors: Pabelick CM,Prakash YS,Kannan MS,Warner DO,Sieck GC

    更新日期:2001-07-01 00:00:00

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    abstract::Because propofol has cerebral effects similar to those observed for barbiturates, we postulated that it too might offer protection against a focal cerebral ischemic insult. Spontaneously hypertensive male rats were anesthetized with halothane (in 50% O2/balance N2), and their tracheas were intubated and their lungs me...


    pub_type: 杂志文章


    authors: Ridenour TR,Warner DS,Todd MM,Gionet TX

    更新日期:1992-05-01 00:00:00

  • Porcine malignant hyperthermia: effects of halothane on mitochondrial respiration and calcium accumulation.

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    pub_type: 杂志文章


    authors: Britt BA,Endrenyi L,Cadman DL,Fan HM,Fung HY

    更新日期:1975-03-01 00:00:00

  • Effects of desflurane in senescent rat myocardium.

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    pub_type: 杂志文章


    authors: Rozenberg S,Besse S,Amour J,Vivien B,Tavernier B,Riou B

    更新日期:2006-11-01 00:00:00

  • Radiologic localization of the laryngeal mask airway in children.

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    pub_type: 杂志文章


    authors: Goudsouzian NG,Denman W,Cleveland R,Shorten G

    更新日期:1992-12-01 00:00:00

  • A randomized study of the effects of single-dose gabapentin versus placebo on postoperative pain and morphine consumption after mastectomy.

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    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Dirks J,Fredensborg BB,Christensen D,Fomsgaard JS,Flyger H,Dahl JB

    更新日期:2002-09-01 00:00:00

  • Enhancement of spinal N-methyl-D-aspartate receptor function by remifentanil action at delta-opioid receptors as a mechanism for acute opioid-induced hyperalgesia or tolerance.

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    pub_type: 杂志文章


    authors: Zhao M,Joo DT

    更新日期:2008-08-01 00:00:00