A brief regional ischemic-reperfusion enhances propofol-induced depression in left ventricular function of in situ rat hearts.

abstract：:The slow positive (P2) wave of the evoked electrospinogram was recorded from the dorsal epidural space in man. The waveform characteristics of the P2 wave were similar to those of the dorsal cord positive wave (P wave), which is believed to be caused by the primary afferent depolarization (PAD) and to be related to pr...

journal_title：Anesthesiology

authors： Shimoji K,Ito Y,Oama K,Sawa T,Ikezono E

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Spontaneous breaths during airway pressure release ventilation (APRV) have to overcome the resistance of the artificial airway. Automatic tube compensation provides ventilatory assistance by increasing airway pressure during inspiration and lowering airway pressure during expiration, thereby compensating for...

journal_title：Anesthesiology

authors： Wrigge H,Zinserling J,Hering R,Schwalfenberg N,Stüber F,von Spiegel T,Schroeder S,Hedenstierna G,Putensen C

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Halothane and isoflurane have been reported to suppress the contraction of vascular smooth muscle, although the exact mechanism has not been explained fully. This study examined the effect of halothane and isoflurane on cytosolic calcium ion (Ca2+) concentrations ([Ca2+]cyt), which was measured simultaneousl...

journal_title：Anesthesiology

authors： Tsuchida H,Namba H,Yamakage M,Fujita S,Notsuki E,Namiki A

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:The noble gas xenon (Xe) has been used as an inhalational anesthetic agent in clinical trials with little or no physiologic side effects. Like nitrous oxide, Xe is believed to exert minimal unwanted cardiovascular effects, and like nitrous oxide, the vapor concentration to achieve 1 minimum alveolar concentr...

journal_title：Anesthesiology

authors： Stowe DF,Rehmert GC,Kwok WM,Weigt HU,Georgieff M,Bosnjak ZJ

更新日期：2000-02-01 00:00:00

abstract：INTRODUCTION:Opioids are powerful analgesics, but are also common drugs of abuse. Few studies have examined how neuropathic pain alters the pharmacology of opioids in modulating limbic pathways that underlie abuse liability. METHODS:Rats with or without spinal nerve ligation (SNL) were implanted with electrodes into t...

journal_title：Anesthesiology

authors： Ewan EE,Martin TJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Anesthetic drugs administered to immature animals may cause neurohistopathologic changes and alterations in behavior. The authors studied association between anesthetic exposure before age 4 yr and the development of reading, written language, and math learning disabilities (LD). METHODS:This was a populati...

journal_title：Anesthesiology

authors： Wilder RT,Flick RP,Sprung J,Katusic SK,Barbaresi WJ,Mickelson C,Gleich SJ,Schroeder DR,Weaver AL,Warner DO

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Rocuronium, like other steroidal nondepolarizing muscle relaxants, may in part be eliminated by the liver. To determine the influence of liver disease on its neuromuscular blocking effect, we studied the pharmacokinetics and pharmacodynamics of rocuronium in patients with cirrhosis. METHODS:Eighteen patient...

journal_title：Anesthesiology

authors： Khalil M,D'Honneur G,Duvaldestin P,Slavov V,De Hys C,Gomeni R

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Synergistic antinociception of opioids and local anesthetics has been established in bolus injections but not in long-term use. The somatic and visceral antinociceptive effects of intrathecally infused morphine or lidocaine were characterized, and the nature of the interaction of those agents in rats was eva...

journal_title：Anesthesiology

authors： Saito Y,Kaneko M,Kirihara Y,Sakura S,Kosaka Y

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Sedative-hypnotic drugs not only increase sedation, but also impair memory as serum concentration increases. These drugs also produce profound changes in the auditory event-related potential (ERP). The ability of various ERP components to predict changes in sedation and memory produced by various drugs was t...

journal_title：Anesthesiology

authors： Veselis RA,Reinsel RA,Feshchenko VA

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Postoperative nausea and vomiting (PONV) occurs frequently after gynecologic surgery. Because hemodynamic condition seems to be influential, women presenting with preoperative orthostatic dysregulation may have an increased risk for PONV. The aim of the present study was to assess the relationship between pr...

journal_title：Anesthesiology

authors： Pusch F,Berger A,Wildling E,Zimpfer M,Moser M,Sam C,Krafft P

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Halothane induces negative inotropic and lusitropic effects in myocardium. It has been suggested that halothane potentiates beta-adrenoceptor stimulation. However, its effects on the inotropic response to alpha-adrenoceptor stimulation and its effects on the lusitropic effects of alpha- and beta-adrenoceptor...

journal_title：Anesthesiology

authors： Hanouz JL,Riou B,Massias L,Lecarpentier Y,Coriat P

更新日期：1997-01-01 00:00:00

abstract：:Reversal of the usual relationship between aortic and radial artery pressure can occur in patients following cardiopulmonary bypass. Radial systolic (and often radial mean) pressures were lower, relative to aortic pressure, after cardiopulmonary bypass than before bypass in all 18 patients studied. The systolic pressu...

journal_title：Anesthesiology

authors： Stern DH,Gerson JI,Allen FB,Parker FB

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Ethical conduct in human research in anesthesia includes approval by an institutional review board (IRB) or ethics committee and informed consent. Evidence of these is sometimes lacking in journal publications. METHODS:The authors reviewed all publications involving human subjects in six leading anesthesia ...

journal_title：Anesthesiology

authors： Myles PS,Tan N

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine whether combination of 1-5 microg intrathecal neostigmine would enhance analgesia from a fixed intrathecal dose of morphine. METHODS:A total of 60 patients undergoing gynecologic surgery were randomized to one of five groups. Patients received 15 mg bupivacaine plu...

journal_title：Anesthesiology

authors： Almeida RA,Lauretti GR,Mattos AL

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:We aimed to assess the clinical effectiveness of intravenous exenatide compared to insulin in perioperative blood glucose control in coronary artery bypass grafting surgery patients. METHODS:Patients more than 18 yr old admitted for elective coronary artery bypass grafting were included in a phase II/III no...

journal_title：Anesthesiology

authors： Besch G,Perrotti A,Mauny F,Puyraveau M,Baltres M,Flicoteaux G,Salomon du Mont L,Barrucand B,Samain E,Chocron S,Pili-Floury S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Densities in dependent lung regions worsen oxygenation in patients with acute respiratory distress syndrome. Identification of these densities requires examination using computed tomography (CT). In this study, the authors evaluated the use of transesophageal echocardiography (TEE) to estimate densities in t...

journal_title：Anesthesiology

authors： Tsubo T,Sakai I,Suzuki A,Okawa H,Ishihara H,Matsuki A

更新日期：2001-05-01 00:00:00

abstract：:The anesthetic effects and interactions of midazolam and fentanyl were determined in terms of their reduction of enflurane MAC in dogs, and the effects of their specific antagonists were also investigated. Control enflurane MAC was determined by the tail clamp method in 18 mongrel dogs. Each animal then received an iv...

journal_title：Anesthesiology

authors： Schwieger IM,Hall RI,Szlam F,Hug CC Jr

更新日期：1989-04-01 00:00:00

abstract：BACKGROUND:Single lung transplantation has become a viable therapy for treatment of end-stage pulmonary disease. We previously observed that left lung autotransplantation (LLA) results in a chronic increase in pulmonary vascular resistance and enhanced pulmonary vascular reactivity to sympathetic alpha adrenoreceptor a...

journal_title：Anesthesiology

authors： Lennon PF,Murray PA

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Mechanical ventilation is delivered to sedated patients during anesthesia, but also to nonsedated patients (ventilator weaning, noninvasive ventilation). In these circumstances, patient-ventilator asynchrony may occur, provoking discomfort and unduly increasing work of breathing. In certain cases, it is asso...

journal_title：Anesthesiology

authors： Raux M,Ray P,Prella M,Duguet A,Demoule A,Similowski T

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Halothane has been previously shown in vitro to decrease both the inward calcium current in isolated cells and the density of calcium antagonist binding sites in cardiac sarcolemmal membranes prepared from several species, including humans, presumably contributing to the negative inotropic effects seen with ...

journal_title：Anesthesiology

authors： Lee DL,Zhang J,Blanck TJ

更新日期：1994-11-01 00:00:00

abstract：:The effects of halothane (0.75% and 1.5%) and isoflurane (2.6%) on macroscopic Ca2+ and K+ channel currents (ICa and IK, respectively) were investigated in voltage-clamped vascular muscle cells from the canine coronary artery. Single coronary arterial cells were dialyzed with K+ glutamate solution and superfused with ...

journal_title：Anesthesiology

authors： Buljubasic N,Rusch NJ,Marijic J,Kampine JP,Bosnjak ZJ

更新日期：1992-06-01 00:00:00

abstract：INTRODUCTION:The current investigation aimed to study the efficacy of hemostatic therapy guided either by conventional coagulation analyses or point-of-care (POC) testing in coagulopathic cardiac surgery patients. METHODS:Patients undergoing complex cardiac surgery were assessed for eligibility. Those patients in whom...

journal_title：Anesthesiology

authors： Weber CF,Görlinger K,Meininger D,Herrmann E,Bingold T,Moritz A,Cohn LH,Zacharowski K

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Systemically administered local anesthetics and other sodium channel blockers produce analgesia in patients with hypersensitivity disorders. To assess whether these agents have a role in the treatment of visceral pain, the present study examined the effects of intravenous lidocaine on neuronal and reflex res...

journal_title：Anesthesiology

authors： Ness TJ

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The severity of spontaneous myocardial hypercarbic acidosis during cardiac arrest previously has been predictive of the likelihood of restoring spontaneous circulation. The present study investigated whether hypercarbia itself impairs cardiac resuscitation. Since coronary perfusion pressure is the overriding...

journal_title：Anesthesiology

authors： Maldonado FA,Weil MH,Tang W,Bisera J,Gazmuri RJ,Johnson B,D'Alessio A

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Pain behavior in response to skin incision is developmentally regulated, but little is known about the underlying neuronal mechanisms. The authors hypothesize that the spatial activation and intensity of dorsal horn neuron responses to skin incision differ in immature and adult spinal cord. METHODS:Single w...

journal_title：Anesthesiology

authors： Ririe DG,Bremner LR,Fitzgerald M

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Due to economic pressures and improvements in perioperative care, outpatient surgical procedures have become commonplace. However, risk factors for outpatient surgical morbidity and mortality remain unclear. There are no multicenter clinical data guiding patient selection for outpatient surgery. The authors ...

journal_title：Anesthesiology

authors： Mathis MR,Naughton NN,Shanks AM,Freundlich RE,Pannucci CJ,Chu Y,Haus J,Morris M,Kheterpal S

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Anesthetic preconditioning (APC) with sevoflurane reduces myocardial ischemia-reperfusion injury. The authors tested whether two brief exposures to sevoflurane would lead to a better preconditioning state than would a single longer exposure and whether dual exposure to a lower (L) concentration of sevofluran...

journal_title：Anesthesiology

authors： Riess ML,Kevin LG,Camara AK,Heisner JS,Stowe DF

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Airway pressure-release ventilation provides ventilation comparable to controlled mechanical ventilation (CMV), but with lower peak airway pressures and less dead-space ventilation. To obtain these advantages for patients administered general anesthesia, the authors (1) designed a mode similar to airway pres...

journal_title：Anesthesiology

authors： Bratzke E,Downs JB,Smith RA

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:In animals, systemic and intrathecal administration of the alpha2 -adrenergic receptor agonist dexmedetomidine results in robust antinociceptive effects in models of heat pain. In humans, systemically administered dexmedetomidine is approved for sedating patients in the intensive care unit. However, whether ...

journal_title：Anesthesiology

authors： Angst MS,Ramaswamy B,Davies MF,Maze M

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Optimal analgesia for total knee arthroplasty remains challenging. Many modalities have been used, including peripheral nerve block, periarticular infiltration, and epidural analgesia. However, the relative efficacy of various modalities remains unknown. The authors aimed to quantify and rank order the effic...

journal_title：Anesthesiology

authors： Terkawi AS,Mavridis D,Sessler DI,Nunemaker MS,Doais KS,Terkawi RS,Terkawi YS,Petropoulou M,Nemergut EC

更新日期：2017-05-01 00:00:00