Epilepsy, vagal nerve stimulation by the NCP system, all-cause mortality, and sudden, unexpected, unexplained death.

abstract：OBJECTIVE:To identify the brain networks that are involved in the different electroencephalography (EEG) abnormalities in patients with ring chromosome 20 [r(20)] syndrome. We hypothesize the existence of both distinctive and common brain circuits for the paroxysmal high voltage sharp waves (hSWs), the seizures, and th...

journal_title：Epilepsia

authors： Vaudano AE,Ruggieri A,Vignoli A,Avanzini P,Benuzzi F,Gessaroli G,Nichelli PF,Darra F,Cantalupo G,Mastrangelo M,Dalla Bernardina B,Canevini MP,Meletti S

更新日期：2014-03-01 00:00:00

abstract：PURPOSE:Chronic cellular inflammation closely associated with epilepsy without an active infection is a hallmark of Rasmussen encephalitis (RE). RE has typical and defining features lacking in other rare epilepsy patients who also have neocortical lymphocytes without an identifiable cause. A patient with malformations ...

journal_title：Epilepsia

authors： Rhodes RH,Lehman RM,Wu BY,Roychowdhury S

更新日期：2007-06-01 00:00:00

abstract：:Our understanding of the neural mechanisms of non-rapid eye movement sleep (NREM) is steadily increasing. Given the intriguing activation of paroxysmal activity during NREM sleep in patients with Landau-Kleffner syndrome (LKS), a thorough characterization of commonalities and differences between the neural correlates ...

journal_title：Epilepsia

authors： Mascetti L,Foret A,Bonjean M,Matarazzo L,Dang-Vu T,Maquet P

更新日期：2009-08-01 00:00:00

abstract：:Eleven patients had seizures with unilateral temporal lobe onset recorded with simultaneous bilateral medial temporal depth electrodes and neocortical (subdural) electrodes at least on the side of seizure onset. Of a total of 55 seizures, four had simultaneous onset in neocortex and hippocampus, and 51 had onset in un...

journal_title：Epilepsia

authors： Spencer SS,Williamson PD,Spencer DD,Mattson RH

更新日期：1987-09-01 00:00:00

abstract：:We performed a retrospective study of 51 consecutive patients who underwent operation for intractable partial epilepsy related to low-grade intracerebral neoplasms between 1984 and 1990. All patients had medically refractory partial seizures and a mass lesion identified on neuroimaging studies. Lesionectomy was perfor...

journal_title：Epilepsia

authors： Britton JW,Cascino GD,Sharbrough FW,Kelly PJ

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:Surgical resection of seizure-producing brain tissue is a gold standard treatment for drug-resistant focal epilepsy. However, several patient-specific factors can preclude resective surgery, including a spatially extensive ("regional") seizure-onset zone (SOZ). For such patients, responsive neurostimulation (...

journal_title：Epilepsia

authors： Ma BB,Fields MC,Knowlton RC,Chang EF,Szaflarski JP,Marcuse LV,Rao VR

更新日期：2020-01-01 00:00:00

abstract：:Absence epilepsy is a form of generalized epilepsy commonly seen in children. The neuronal process by which ethosuximide (ETX), a first choice anti-absence drug, prevents absence seizures is still unresolved. Recent clinical findings have indicated that focal cortical regions are involved during absence seizures. Cons...

journal_title：Epilepsia

authors： Polack PO,Charpier S

更新日期：2009-07-01 00:00:00

abstract：:Immune abnormalities have been found in epileptic patients receiving antiepileptic drugs (AEDs). Phenytoin (PHT) produces a decrease in serum IgA and IgM levels and a decrease in blastic transformation of circulating lymphocytes stimulated with phytohemoagglutinin (PHA). The effects of carbamazepine (CBZ) on the immun...

journal_title：Epilepsia

authors： Pacifici R,Paris L,Di Carlo S,Pichini S,Zuccaro P

更新日期：1991-01-01 00:00:00

abstract：:The in vitro effects of four antiepileptic drugs (AEDs) on human sperm motility were studied with a transmembrane migration method. Sperm motility of epileptic patients receiving chronic AED therapy was also investigated. Sperm motility was measured immediately after semen had been mixed with AED and after a 2-h prein...

journal_title：Epilepsia

authors： Chen SS,Shen MR,Chen TJ,Lai SL

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:In mesial temporal lobe epilepsy (MTLE) the epileptogenic area is confined to the mesial temporal lobe, but other cortical and subcortical areas are also affected and cognitive and psychiatric impairments are usually documented. Functional connectivity methods are based on the correlation of the blood oxygen le...

journal_title：Epilepsia

authors： Pittau F,Grova C,Moeller F,Dubeau F,Gotman J

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Interictal spikes are a characteristic feature of invasive electroencephalography (EEG) recordings in children with refractory epilepsy. Spikes frequently co-occur across multiple brain regions with discernable latencies, suggesting that spikes can propagate through distributed neural networks. The purpose of...

journal_title：Epilepsia

authors： Tomlinson SB,Wong JN,Conrad EC,Kennedy BC,Marsh ED

更新日期：2019-05-01 00:00:00

abstract：:Clinically, and in experimental models, perinatal hypoxic encephalopathy is commonly associated with seizures. We previously described a rat model in which hypoxia induces seizures and permanently increases in seizure susceptibility in immature rats [postnatal day (P) 10-12] but not in older rats. In the present study...

journal_title：Epilepsia

authors： Jensen FE,Blume H,Alvarado S,Firkusny I,Geary C

更新日期：1995-10-01 00:00:00

abstract：:Mutations of the sodium channel subunit gene SCN2A have been described in families with benign familial neonatal-infantile seizure (BFNIS). We describe two large families with BFNIS and novel SCN2A mutations. The families had 12 and 9 affected individuals, respectively, with phenotypes consistent with BFNIS. Two mutat...

journal_title：Epilepsia

authors： Herlenius E,Heron SE,Grinton BE,Keay D,Scheffer IE,Mulley JC,Berkovic SF

更新日期：2007-06-01 00:00:00

abstract：:People with epilepsy (PWEs) are often advised against participating in sports and exercise, mostly because of fear, overprotection, and ignorance about the specific benefits and risks associated with such activities. Available evidence suggests that physical exercise and active participation in sports may favorably af...

journal_title：Epilepsia

authors： Capovilla G,Kaufman KR,Perucca E,Moshé SL,Arida RM

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Although anterior temporal lobectomy (ATL) is an effective treatment for many patients with medically refractory temporal lobe epilepsy (TLE), one risk associated with this procedure is postsurgical decline in memory. A substantial number of past studies examined factors that predict memory decline after surger...

journal_title：Epilepsia

authors： Lineweaver TT,Morris HH,Naugle RI,Najm IM,Diehl B,Bingaman W

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:To assess the visual system excitability of photosensitive patients with idiopathic generalized epilepsy (IGE) with the paired-pulse flash-evoked potential (paired F-VEP) technique. METHODS:We studied 19 photosensitive patients with IGE (16 women) showing a photoparoxysmal electroencephalographic (EEG) respons...

journal_title：Epilepsia

authors： Strigaro G,Prandi P,Varrasi C,Monaco F,Cantello R

更新日期：2012-04-01 00:00:00

abstract：:Visual behavior is frequently impaired at onset of West syndrome (WS). We studied the neuropsychological outcome of eight children who had cryptogenic WS and moderate to severe visual impairment at the onset of epilepsy. At the last examination, a regional cerebral blood flow study using SPECT (single photon emission ...

journal_title：Epilepsia

authors： Jambaqué I,Chiron C,Dulac O,Raynaud C,Syrota P

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:Despite national guidelines supporting surgical referral in drug-resistant epilepsy, it is hypothesized that surgery is underutilized. We investigated the volumes of lobectomy/amygdalohippocampectomy surgeries over time and examined differences in outcomes between (1) high-volume (HV), middle-volume (MV), and...

journal_title：Epilepsia

authors： Kwon CS,Blank L,Mu L,Jetté N

更新日期：2020-10-01 00:00:00

abstract：PURPOSE:Compelling evidence supports the presence of P450 enzymes (CYPs) in the central nervous system (CNS). However, little information is available on the localization and function of CYPs in the drug-resistant epileptic brain. We have evaluated the pattern of expression of the specific enzyme CYP3A4 and studied its...

journal_title：Epilepsia

authors： Ghosh C,Marchi N,Desai NK,Puvenna V,Hossain M,Gonzalez-Martinez J,Alexopoulos AV,Janigro D

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:Guidelines recommend that encephalopathic critically ill children undergo continuous electroencephalographic (CEEG) monitoring for electrographic seizure (ES) identification and management. However, limited data exist on antiseizure medication (ASM) safety for ES treatment in critically ill children. METHODS...

journal_title：Epilepsia

authors： Fung FW,Jacobwitz M,Vala L,Parikh D,Donnelly M,Xiao R,Topjian AA,Abend NS

更新日期：2019-10-01 00:00:00

abstract：:The identification and correction of adverse physiological changes that lead to seizures in children can improve the effectiveness of current therapeutic practices in epilepsy. It is proposed that various circadian rhythms (respiration, hormones, water balance, electrolytes, intracranial pressure, blood pressure), met...

journal_title：Epilepsia

authors： LeWinn EB

更新日期：1980-08-01 00:00:00

abstract：:Many patients with medically refractory epilepsy now undergo successful surgery based on noninvasive diagnostic information, but intracranial electroencephalography (IEEG) continues to be used as increasingly complex cases are considered surgical candidates. The indications for IEEG and the modalities employed vary ac...

journal_title：Epilepsia

authors： Jayakar P,Gotman J,Harvey AS,Palmini A,Tassi L,Schomer D,Dubeau F,Bartolomei F,Yu A,Kršek P,Velis D,Kahane P

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize the incidence and etiology of temporal lobe epilepsy (TLE) in a community-based cohort of children with new-onset disease. METHODS:A community-based cohort of 30 children with TLE was studied. The patients had new-onset disease before age 14 years between 1995 and 1999...

journal_title：Epilepsia

authors： Sztriha L,Gururaj AK,Bener A,Nork M

更新日期：2002-01-01 00:00:00

abstract：:The suppressive effect of sunglasses upon photoparoxysmal responses (PPRs) elicited by 15-Hz flicker stimuli with a low luminance of nearly 10 nits was studied in eight patients with photosensitive epilepsy. Using three commercially available sunglasses of neutral density (ND), blue, and brown, the influence upon gene...

journal_title：Epilepsia

authors： Takahashi T,Tsukahara Y

更新日期：1992-05-01 00:00:00

abstract：:Nocturnal frontal lobe epilepsy (NFLE) is a condition primarily characterized by seizures occurring exclusively or predominantly during sleep, the semiology of which suggest a frontal lobe origin and, more specifically, the involvement of the orbitofrontal or mesial frontal regions. It is usually considered as a relat...

journal_title：Epilepsia

authors： Ryvlin P,Rheims S,Risse G

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:To determine the cerebral electroencephalography (EEG) substrates of scalp EEG seizure patterns, such as source area and synchrony, and in so doing assess the limitations of scalp seizure recording in the localization of seizure onset zones in patients with temporal lobe epilepsy. METHODS:We recorded simultane...

journal_title：Epilepsia

authors： Tao JX,Baldwin M,Ray A,Hawes-Ebersole S,Ebersole JS

更新日期：2007-11-01 00:00:00

abstract：PURPOSE:The role of the superior colliculus (SC) in seizure expression is controversial and appears to be dependent upon the epilepsy model. This study shows the effect of disconnection between SC deep layers and adjacent tissues in the expression of acute and kindling seizures. METHODS:Subcollicular transections, abl...

journal_title：Epilepsia

authors： Doretto MC,Cortes-de-Oliveira JA,Rossetti F,Garcia-Cairasco N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of NBQX (2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f) quinoxaline-2,3-dione) and topiramate (TPM) given after hypoxia-induced seizures in preventing the delayed effect of hypoxia on subsequent susceptibility to seizures and neuronal injury. METHODS:We used "two-hit" rodent seizure model t...

journal_title：Epilepsia

authors： Koh S,Tibayan FD,Simpson JN,Jensen FE

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:The role of alpha 1b-adrenergic receptor (alpha 1b-AR) in relation with neuronal degeneration, drug addiction, and seizure susceptibility has recently emerged. In particular, mice that overexpress alpha 1b-AR undergo spontaneous epileptic seizures and progressive neuronal loss in a variety of brain areas. There...

journal_title：Epilepsia

authors： Pizzanelli C,Lazzeri G,Fulceri F,Giorgi FS,Pasquali L,Cifelli G,Murri L,Fornai F

更新日期：2009-01-01 00:00:00

abstract：:A child had two to three generalized tonic-clonic (GTC) seizures per week unresponsive to phenobarbital (PB) and valproate (VPA). Interictal EEG demonstrated left occipital spikes. When carbamazepine (CBZ) therapy was started, he developed very frequent (4-6/day) complex partial seizures (CPS) characterized on ictal E...

journal_title：Epilepsia

authors： Dhuna A,Pascual-Leone A,Talwar D

更新日期：1991-03-01 00:00:00