Abstract:
:A secondary structure sequence is a symbolic string composed of three kinds of letters, indicating the helix, strand, and coil (including turns), respectively. A graphic representation for this abstract symbolic sequence is proposed here, called the S curve. The S curve is the unique representation for a given secondary structure sequence in the sense that the sequence and the S curve can be uniquely determined from the other. Therefore, the S curve contains all the information that the secondary structure sequence contains. Different geometrical properties of the S curve are studied in details, which reflect the basic characteristics of the secondary structure sequences. The S curves are used to display, analyze, and compare the secondary structure sequences. Detailed application examples are presented. One advantage of the S curve methodology is that the main patterns of a given secondary structure sequence can be grasped quickly in a perceivable form. This is particularly useful in the cases in which longer sequences are involved and structures of proteins are unknown.
journal_name
Biopolymersjournal_title
Biopolymersauthors
Zhang CT,Zhang Rdoi
10.1002/(SICI)1097-0282(200006)53:7<539::AID-BIP2>subject
Has Abstractpub_date
2000-06-01 00:00:00pages
539-49issue
7eissn
0006-3525issn
1097-0282pii
10.1002/(SICI)1097-0282(200006)53:7<539::AID-BIP2>journal_volume
53pub_type
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