Abstract：
OBJECTIVES:We show the effectiveness of treatment with continuous intrathecal baclofen infusion in a case of hereditary generalized dystonia refractory to anticholinergics, tetrabenazine, pimozide, L-dopa, benzodiazepines and thalamotomy. CLINICAL CASE:A 26 years old female patient, when she was 11 years old began with torsion dystonia in her left feet, that progressively worsened to involve her entire body. She had painful spasms. She had four brothers, three of them with dystonia and one healthy. Her uncle grandfather had similar symptoms. Complementary explorations to reject secondary origin was negatives. She was treated with high and progressive dosages of anticholinergics, pimozide, tetrabenazine, benzodiazepines, L-dopa and thalamotomy without improvement. Underwent intrathecal baclofen test dosing, we used 25, 50, 100 micrograms/day, the last one with improvement during 10 hours. A pump was inserted with an initial dose of 220 micrograms/day. After pump insertion, baclofen dosage was gradually increased to 450 micrograms/day. She had a great improvement in right part of her body and less in her left body. Painful spasms had disappeared. CONCLUSION:We propose continuous baclofen intrathecal infusion pump for patients with severe torsion dystonia that not response to ordinal treatment.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Grande MA,Chacón J,Trujillo A,García-Moreno JM,Bravo Msubject
Has Abstractpub_date
2000-01-16 00:00:00pages
138-40issue
2eissn
0210-0010issn
1576-6578journal_volume
30pub_type
杂志文章abstract：INTRODUCTION:The developmental amnesia is a recently known entity that occurs as a consequence of hypoxic-ischemic events in the perinatal period. This is a specific deficit of episodic memory with greater preservation of semantic memory and other memory components such as the immediate and working memory. It occurs in...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Language widely varies in children with autism spectrum disorders (ASD). Evidence, however, suggests that these children understand language worse than their peers with typical development, showing a delay in acquisition of receptive vocabulary. Research relating quality of life (QOL) and language is limit...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:From studies of the incidence of epilepsy, figures of between 40 and 70 per 100,000 inhabitants are obtained whilst in studies of prevalence, 5 to 7 cases per 1,000 are found. Cerebrovascular disease is the commonest cause of epileptic crises in the developed world, being more frequent in patients aged over 60, who ma...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-02-01 00:00:00
abstract：INTRODUCTION:Transcranial Doppler (TCD) is a new technique which is becoming increasingly used in neurology and is highly dependent on the user. OBJECTIVE:To evaluate the reliability of TCD in our hospital. PATIENTS AND METHODS:During a five month period, all patients who had a cerebral angiogram done, also had DTC w...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-09-16 00:00:00
abstract：INTRODUCTION:OnabotulinumtoxinA (OnabotA) is indicated for headache prophylaxis in patients with chronic migraine. However, there is some controversy about what is the minimum effective dose for treating chronic migraine patients. AIM:To determine the optimal dose of OnabotA for the prophylactic treatment of patients ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2014-03-10 00:00:00
abstract：INTRODUCTION:Arterial gas embolism (AGE) is a main iatrogenic complication resulting from the use of invasive procedures. It is difficult to diagnose if it is not clinically suspected. CASE REPORT:A 67-year-old male patient, with a history of interventions involving a mitral prosthesis and a double aortocoronary bypas...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：INTRODUCTION:Meningioma is one of the most frequent tumours affecting the central nervous system, with an estimated incidence of between 15 and 20% of all brain tumours. They are generally benign and slow growing. Their appearing as a cerebral infarction is very rare. CASE REPORT:A right-handed 75-year-old female pati...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:To review about this disorder, with emphasis on the intensive care of severe Guillain Barr syndrome (GBS). DEVELOPMENT:GBS is an acute immune mediated inflammatory polyneuropathy that may lead to quadriparesis, ventilatory failure, and autonomic dysfunction but also to many general medical problems that have...
journal_title：Revista de neurologia
pub_type： 历史文章,杂志文章,评审
doi：
更新日期：2002-05-16 00:00:00
abstract：AIMS:We outline a proposal for the structural and functional features needed to develop a registry of dementias which can be used to collect standardised information that is both reliable and valid concerning cases of dementia in the specialised health care centres within a particular geographical area. DEVELOPMENT:Du...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-07-01 00:00:00
abstract：INTRODUCTION:Valproic acid (VPA) is a useful antiepileptic drug for controlling different types of epilepsy. It has several side effects and is associated to increased body weight, as well as metabolic and endocrine disorders, including metabolic syndrome. AIM:To determine the prevalence of obesity and metabolic syndr...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：: TITLE:Utilidad de la resonancia magnetica craneal para el diagnostico de la distrofia miotonica de tipo 1. : ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2019-02-01 00:00:00
abstract：INTRODUCTION AND AIMS:The exploration of neurocognition in neurology departments has gone a long way from the traditional psychometric tests to the present day use of high technology methods in cognitive neurophysiology, as is the case of event related potentials. Given the increased sensitivity of these procedures, it...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-11-01 00:00:00
abstract：OBJECTIVE:The literature on clinical and physiophatologic characteristics of the spectrum of memory disorders in childhood is reviewed in this article. DEVELOPMENT:There are only a few detailed reports of permanent specific memory disorders in children. Early anoxo ischaemic bihippocampal injuries can cause a selectiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVES:The published data on neurological resources and the demand for neurological care in Spain were reviewed. Also, this demand was analysed in a specific health district (area 11, Hospital Universitario 12 de Octubre, Madrid). DEVELOPMENT:About 2.5 neurologists per 100,000 inhabitants in Spain was estimated to...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-01 00:00:00
abstract：:Studies of vision using electrophysiological techniques are tests which record functional alterations in very early phases of a disease. Full field flash ERG evaluates the integrity of the cones, rods and bipolar cells. It is obtained by photopsic stimulation with Ganzfeld and contact lens corneal electrodes or, alter...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-02-15 00:00:00
abstract：INTRODUCTION:Although visual symptoms of multiple sclerosis (MS) are very frequent, they are rarely related with treatment with interferon. This is the first case reported in the literature of retinopathy associated with subcutaneous interferon beta-1a, and the second related to interferons in MS. CASE REPORT:A 30-yea...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-04-16 00:00:00
abstract：INTRODUCTION:The capability of the electroencephalography (EEG) of recording the bioelectrical activity of the brain has made of it a fundamental tool for the evaluation of the patient's neurological condition. In recent years, moreover, it has also begun to be used in obtaining information for other kind of variables,...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.6809.2018179
更新日期：2019-05-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-10-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-11-16 00:00:00
abstract：INTRODUCTION:Neurocystercicosis (NCC) is a disorder caused by the Taenia solium larva. It is the commonest parasitosis of the CNS. In Spain most patients are from countries where the condition is endemic. However, sporadic cases still occur amongst the non immigrant population of rural regions. We report a new case of ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-02-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-05-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-11-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2007-11-16 00:00:00
abstract：INTRODUCTION AND DEVELOPMENT:The paraneoplastic neurological syndromes are alterations associated with neoplasias. However, they are not caused by metastases or complications such as infections, vascular disorders, metabolic or nutritional alterations or secondary effect of treatment. The paraneoplastic syndromes are o...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2002-10-16 00:00:00
abstract：BACKGROUND:The aortic atherosclerotic debris is considered a high risk embolic source, being an independent predictor for cerebrovascular ischemia. The incidence is higher in the elderly and in patients with coronary artery disease. Transesophageal echocardiogram (TEE) is an important diagnostic tool that allows its de...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2003-06-16 00:00:00
abstract：INTRODUCTION:Virtual reality allows the user to interact with elements within a simulated scene. In recent times we have been witness to the introduction of virtual reality-based devices as one of the most significant novelties in neurorehabilitation. AIM:To review the clinical applications of the developments based o...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2010-10-16 00:00:00
abstract：INTRODUCTION:Studies on focal dystonia showed that the formulations of botulinum toxin type A, incobotulinumtoxin-A (Inco-BTA) and onabotulinumtoxin-A (Ona-BTA), have equivalent efficacy and safety. AIM:To carry-out a cost-utility analysis of Inco-BTA administered on flexible intervals vs. Ona-BTA on a fixed interval,...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-12-16 00:00:00
