[Guillain Barre syndrome].

Abstract:

OBJECTIVE:To review about this disorder, with emphasis on the intensive care of severe Guillain Barr syndrome (GBS). DEVELOPMENT:GBS is an acute immune mediated inflammatory polyneuropathy that may lead to quadriparesis, ventilatory failure, and autonomic dysfunction but also to many general medical problems that have great bearing on outcome. Therefore severe GBS patients require admission into an intensive care unit (ICU), where in addition to the disorders mentioned before, other complications can arise. The neurologist who plans to deal comprehensively with these patients must be familiar with therapy for infections, nutrition, fluid management, and selected aspects of pulmonary medicine as well as the indications for and complications of plasma exchange and gammaglobulin infusion. CONCLUSIONS:With modern intensive care support, the outcome is excellent (>80% recovery), although in many cases a persistent residual paresis occurs. Because GBS is largely self limited, the skill daily cares of these patients in an ICU contributes as much, or more, to the overall outcome of an individual patient as do specific immune therapies.

journal_name

Rev Neurol

journal_title

Revista de neurologia

authors

Tellería-Díaz A,Calzada-Sierra DJ

subject

Has Abstract

pub_date

2002-05-16 00:00:00

pages

966-76

issue

10

eissn

0210-0010

issn

1576-6578

pii

rn2001280

journal_volume

34

pub_type

历史文章,杂志文章,评审
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