Abstract:
AIM:To report a case of sub-acute encephalopathy with all the extension study negative and with response to steroid therapy. CASE REPORT:The study involves a 22-year-old female with no relevant past history who presented symptoms of sub-acute encephalopathy consisting in behavioural disorders, generalised seizures and bradypsychia, which gradually progressed to a state of low-level consciousness. While she was in hospital all kinds of diagnostic tests were conducted, the results of which were either normal or negative; the electroencephalogram was repeatedly abnormal and detection of protein 14-3-3 in cerebrospinal fluid was positive. Empirical corticoid therapy was begun with clinical and electrophysiological improvements and the patient recovered completely without any sequelae. CONCLUSIONS:With no evidence of autoimmune thyroid disease, although non-specific autoimmunity was present, the patient was diagnosed as having non-vasculitic autoimmune meningoencephalitis.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
López-Ariztegui N,Lobato-Casado P,Muñoz-Escudero F,Polo-Martín M,Montes-Gonzalo MC,Alvarez-Tejerina Asubject
Has Abstractpub_date
2009-10-01 00:00:00pages
359-62issue
7eissn
0210-0010issn
1576-6578pii
rn2009211journal_volume
49pub_type
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