Abstract:
:We aim to monitor the trends of antimicrobial resistance in Neisseria gonorrhoeae and to compare the results of antimicrobial sensitivity by disc diffusion and minimum inhibitory concentration (MIC). Two hundred and eleven confirmed strains of N. gonorrhoeae were subjected to antimicrobial sensitivity testing by disc diffusion using penicillin, tetracycline, ciprofloxacin and ceftriaxone from 1995 to June 1999. Penicillinase-producing Neisseria gonorrhoeae (PPNG) were detected by lodometric method. Minimum inhibitory concentration was determined by E test. A low level of penicillin resistance and PPNG detected in 1996 was maintained over the years. Significant increasing trend of tetracycline and ciprofloxacin resistance with high MIC i.e. 2-96 microg/ml and 1-32 microg/ml respectively were found. Ceftriaxone was found to be the drug of choice, being 100% sensitive. Comparison of resistance pattern by the 2 tests showed satisfactory agreement. Emergence of penicillin, quinolone and tetracyline resistance in N. gonorrhoeae isolates from a major STD centre at New Delhi indicates the need for increased awareness, prudent use of antimicrobials, and evaluation of new antimicrobials for the treatment of gonorrhoea. :This study determined the prevalence of antimicrobial resistance by Neisseria gonorrhoeae, including penicillinase-producing gonorrhea (PPNG) strains, and monitored the trends. It further compared the results of antimicrobial sensitivity by disc diffusion and minimum inhibitory concentration (MIC). A total of 211 confirmed gonorrhea strains were subjected to antimicrobial sensitivity testing by disc diffusion using penicillin, tetracycline, ciprofloxacin, and ceftriaxone from 1995 to June 1999. PPNG strains were detected by lodometric method, and an E test method of 55 strains isolated in 1997-98 determined MIC. Statistical analysis of the results indicates that a low level of penicillin resistance and PPNG detected in 1996 was maintained over the years. In addition, a significant increasing trend of tetracycline and ciprofloxacin resistance with high MIC was found. Ceftriaxone, being 100% sensitive, was found to be the drug of choice. Moreover, comparison of resistance pattern by the two tests showed satisfactory agreement. Findings indicate the need for increased awareness, prudent use of antimicrobials, and evaluation of new antimicrobials for the treatment of gonorrhea.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Ray K,Bala M,Kumar J,Misra RSdoi
10.1177/095646240001100209subject
Has Abstractpub_date
2000-02-01 00:00:00pages
115-8issue
2eissn
0956-4624issn
1758-1052journal_volume
11pub_type
杂志文章abstract::The objective of this study was to assess the impact on men's liking for the condoms they use of a range of factors including demographic variables and variables that describe men's experience of using particular condoms. One hundred and ninety-four men used 3765 condoms for which they provided a liking rating. The co...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913907
更新日期:1999-04-01 00:00:00
abstract::Scolecobasidium sp. are commensal soil and water thermophilic dematiaceous fungi. They are commonly isolated as contaminants from respiratory secretions due to their abundant presence in water supplies, but they are also rare yet emerging culprits producing severe opportunistic infections in immunocompromised individu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416646688
更新日期:2017-01-01 00:00:00
abstract::Successful cervical screening programmes depend on the participation of an informed target population. A national cervical screening programme is shortly to be introduced in the Republic of Ireland. We compare the knowledge, attitudes and practice of 395 Irish urban women with 323 high-risk women, genitourinary medici...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011916974
更新日期:2001-03-01 00:00:00
abstract::This study assessed lubricant use during receptive anal intercourse (RAI) among Peruvian men who have sex with men (MSM) and willingness to use a hypothetical rectal microbicide (RM) formulated as a lubricant to prevent HIV infection. Data were collected from 843 Peruvian MSM for the 2008 HIV Sentinel Surveillance usi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2010.010134
更新日期:2010-08-01 00:00:00
abstract::Genital elephantiasis is an important medical problem in the tropics. It usually affects young and productive age group, and is associated with physical disability and extreme mental anguish. The majority of cases are due to filariasis; however, a small but significant proportion of patients develop genital elephantia...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/095646206775809150
更新日期:2006-03-01 00:00:00
abstract::We examined treatment-seeking behaviours amongst a consecutive sample of 188 first-time attenders at a busy genitourinary (GU) clinic in a general hospital. Participants were interviewed and completed a battery of questionnaires prior to receiving diagnosis or treatment. Delay in treatment seeking was measured in 3 wa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001916083
更新日期:2000-06-01 00:00:00
abstract::Advancements in the diagnosis and treatment of testicular cancer now give a five-year survival rate of 97.2%. Delayed presentation remains the primary cause of poor outcome and recommendations have stressed that men, particularly those with risk factors, should undertake regular testicular self-examination. This study...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414522774
更新日期:2014-10-01 00:00:00
abstract::All category III chronic prostatitis cases in two hospital sites were retrospectively reviewed from the year 2000 until 2005. The mean age of the patients was 38.7 years. Of these, 56.6% were St Bartholomew's Genitourinary Medicine Department patients and 43.5% were Southend Genitourinary Medicine Clinic patients. We ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207780658917
更新日期:2007-04-01 00:00:00
abstract::The objective of this study was to quantitatively measure the nature of concurrent sex partnering in two samples of drug users having large numbers of sex partners. The purpose of this study was to measure concurrent sex partnering and overlap in concurrent sex partners in two samples of drug users in which some or al...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
abstract::Women attending a dedicated medical gynaecology and family planning referral clinic for women with HIV were surveyed using a standard questionnaire about their knowledge and attitudes to post-exposure prophylaxis after sexual exposure (PEPSE) and emergency hormonal contraception (EHC). Eighty percent of them had not h...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007159
更新日期:2008-01-01 00:00:00
abstract::In order to determine inpatient hospital mortality rates, causes of mortality and characteristics of inpatients at Kamuzu Central Hospital (KCH) in Lilongwe, Malawi, we conducted a prospective observational study of all patients admitted to KCH medical ward from 20 September 2008 to April 2, 2009. All admission diagno...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011021
更新日期:2011-08-01 00:00:00
abstract::The prevalence of urogenital infection caused by Chlamydia trachomatis was examined in 100 non-pregnant women with cervicitis, and 100 healthy women, in San Salvador City, El Salvador. Pharmacia Chlamydia EIA test was used for the detection of chlamydial antigen in urethral and cervical specimens from all the women. D...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249200300607
更新日期:1992-11-01 00:00:00
abstract::Late HIV diagnosis in the UK remains a major cause of morbidity and mortality. In line with British HIV Association recommendations, we implemented routine HIV Screening in Croydon University Hospital Acute Medical Unit in London after an audit in 2011 revealed very high levels of late diagnosis. Our re-audit assessed...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415597346
更新日期:2016-06-01 00:00:00
abstract::The clinical utility of genotypic drug resistance testing (DRT) in HIV-infected children on antiretroviral therapy (ART) is not well understood. HIV-infected patients aged <19 years undergoing DRT for virological failure were retrospectively enrolled. Indications for DRT and changes in HIV RNA load were recorded. Betw...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412473958
更新日期:2013-07-01 00:00:00
abstract::The aim of this study was to assess HIV prevalence and associated risk behaviours among international truck drivers (TDs) in Azerbaijan. The subjects signed consent and completed a questionnaire. Blood was tested using two rapid HIV tests: Determine and OraQuick. Genotyping was performed on 13 positives. Overall, 3763...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008396
更新日期:2009-07-01 00:00:00
abstract::Little information is available on the prevalence of herpes simplex type-2 (HSV-2) antibodies among groups at potential high risk of HIV in Asia. This study was carried out to determine the prevalence of HSV-2 antibodies and correlates of HSV-2 infection in female sex workers (FSWs) in border provinces of Vietnam. Nin...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206778691176
更新日期:2006-11-01 00:00:00
abstract::Peripheral neuropathy is one of the most common neurological complications of HIV infection with a 30-60% lifetime prevalence. Newer HIV drugs cause less peripheral neuropathy, but patients are now living long enough to develop concomitant diabetes-related, vascular-related, and chemotherapy-related neuropathy so it c...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416656688
更新日期:2017-02-01 00:00:00
abstract::We report a case series of HIV/HCV co-infected patients who underwent preemptive antiretroviral therapy modifications to manage clinically significant drug interactions with HCV therapy. Among the 15 patients reviewed, all changed to a raltegravir-based regimen and none experienced a loss of virologic suppression or i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462415580225
更新日期:2016-03-01 00:00:00
abstract::Background In Kenya, HIV incidence and prevalence have declined. HIV rates are lower in rural areas than in urban areas. However, HIV infection is reported higher in men in rural areas (4.5%) compared to those in urban areas (3.7%). Objectives This study examined HIV knowledge, feelings, and interactions towards HIV-i...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416680764
更新日期:2017-08-01 00:00:00
abstract::Self-inserted vaginal tampons for the molecular diagnosis of non-ulcerative STIs were evaluated. Cervical and vaginal swabs, tampons and urines were collected from 185 first-time antenatal clinic attendees. Cultures and nucleic acid amplification assays (NAA) were performed. The sensitivity of PCR on tampons for Trich...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646204322764271
更新日期:2004-02-01 00:00:00
abstract::Two appetite stimulants, megestrol acetate and cyproheptadine were administered in a randomized trial to 14 patients who had no evidence of opportunistic infection or malabsorption but were wasted (had lost more than 5 kg body weight) as a result of human immunodeficiency virus (HIV) infection. Energy intakes were cal...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/095646249200300409
更新日期:1992-07-01 00:00:00
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journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462961917807
更新日期:1996-07-01 00:00:00
abstract::HIV-1 and HSV-2 are frequent genital co-infections in women. To determine how self-collected genital swabs compare to provider-collected cervicovaginal lavage, paired self-collected genital swabs and cervicovaginal lavage from women co-infected with HIV-1 and HSV-2 were evaluated. Women were in an acyclovir clinical t...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1177/0956462416650123
更新日期:2017-03-01 00:00:00
abstract::A 48-year-old woman with HIV infection developed Cushingoid features while she was taking ritonavir-boosted darunavir. Cushing's syndrome was confirmed due to the drug interaction between ritonavir and budesonide. Diagnosis of iatrogenic Cushing's syndrome in HIV-positive patients who are on ritonavir-boosted protease...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011408
更新日期:2012-07-01 00:00:00
abstract::The current cervical screening guidelines lay the duty of care of women under 25 years of age on genitourinary (GU) medicine clinics. To date there has not been an extensive review of cervical cytology results sourced from GU medicine departments. We reviewed the annual reports of the cervical screening programme, wit...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1258/ijsa.2009.009122
更新日期:2009-10-01 00:00:00
abstract::An innovative six-month, two sessions a week, funded clinical attachment programme was devised and introduced for practical training and experience to meet the demands and requirements of those wishing practical experience and training in genitourinary medicine. This has been generated by interest from previous theore...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462041211234
更新日期:2004-07-01 00:00:00
abstract::Summary Comprehensive testing for asymptomatic sexually transmitted infections in Northern Ireland has traditionally been provided by genitourinary medicine clinics. As patient demand for services has increased while budgets have remained limited, there has been increasing difficulty in accommodating this demand. In M...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413519430
更新日期:2014-09-01 00:00:00
abstract::Seventy-eight men with symptoms of chronic or subacute prostatitis were enrolled. Investigations for the presence of Chlamydia trachomatis in urethral swabs were carried out. The expressed prostatic secretions were additionally examined for Mycoplasma hominis, Ureaplasma urealyticum, Gardnerella vaginalis, other gram-...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462981922395
更新日期:1998-06-01 00:00:00
abstract::HIV disproportionately affects men who have sex with men (MSM). Substance use is common among people living with HIV and may affect antiretroviral therapy adherence. Nevertheless, research examining the association between substance use and viral suppression is lacking. The aims of this study were to determine the ass...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418779663
更新日期:2018-10-01 00:00:00
abstract::This study examined some characteristics of male clinic attenders with urethral chlamydial infection. The prevalence of urethral chlamydial infection among heterosexual men (men who have sex with women [MSW]) was 446 (17%) of 2684 men. Men aged 16-34 years were more likely to have chlamydiae than older men with only c...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646206778145604
更新日期:2006-08-01 00:00:00