Infections in the male genital tract and reactive oxygen species.

abstract：BACKGROUND:Monoamines play important roles in decidualization, implantation, immune modulation and inflammation. Furthermore, monoamines are potent vasoactive mediators that regulate blood flow and capillary permeability. Regulation of the uterine blood flow is important both during menstruation and pregnancy. Adequate...

journal_title：Human reproduction update

authors： Hansson SR,Bottalico B,Noskova V,Casslén B

更新日期：2009-03-01 00:00:00

abstract：:The long-term clinical effects of ethinyl estradiol and the impact on environmental safety of the alkylated estrogen components used in combined contraceptive pills remain the subject of debate. The development of improved methods for the use of progestogen-only contraception would represent a viable and desirable opt...

journal_title：Human reproduction update

authors： Collins J,Crosignani PG,ESHRE Capri Workshop Group.

更新日期：2003-07-01 00:00:00

abstract：:The effects on reproductive tract development in male rats, of neonatal exposure to potent (reference) oestrogens, diethylstilboestrol (DES) and ethinyl oestradiol (EE), with those of two environmental oestrogens, octylphenol and hisphenol A were systematically compared. Other treatments, such as administration of a g...

journal_title：Human reproduction update

authors： Williams K,McKinnell C,Saunders PT,Walker M,Fisher JS,Turner KJ,Atanassova N,Sharpe M

更新日期：2001-05-01 00:00:00

abstract：:Endometriosis is considered primarily a disease of the endometrial-subendometrial unit or archimetra. The clinical picture of endometriosis characterises this disease as a hyperactivation of genuine archimetrial functions such as proliferation, inflammatory defence and peristalsis. While the aetiology of the disease r...

journal_title：Human reproduction update

authors： Leyendecker G,Kunz G,Noe M,Herbertz M,Mall G

更新日期：1998-09-01 00:00:00

abstract：:This review addresses research on gamete donors, recipients, and offspring and demonstrates that the foci on all three within the triad are largely directed at disclosure or anonymity; and each in turn centers on the perceived importance of the genetic link. The importance attached to genetics has led some countries t...

journal_title：Human reproduction update

authors： van den Akker O

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:More than 15 million women, many of reproductive age, were infected with human immunodeficiency virus (HIV) at the end of 2007. As the HIV epidemic evolves, heterosexual intercourse is increasingly risky: the risk of infection in exposed young women is 4- to 7-fold higher than in young men and nearly half a ...

journal_title：Human reproduction update

authors： Heikinheimo O,Lähteenmäki P

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Infertility is estimated to affect as many as 186 million people worldwide. Although male infertility contributes to more than half of all cases of global childlessness, infertility remains a woman's social burden. Unfortunately, areas of the world with the highest rates of infertility are often those with p...

journal_title：Human reproduction update

authors： Inhorn MC,Patrizio P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The existence of stem/progenitor cells in the endometrium was postulated many years ago, but the first functional evidence was only published in 2004. The identification of rare epithelial and stromal populations of clonogenic cells in human endometrium has opened an active area of research on endometrial st...

journal_title：Human reproduction update

authors： Gargett CE,Schwab KE,Deane JA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:A dynamic balance between pro- and anti-inflammatory factors contributes to regulating human female reproduction. Chronic low-grade inflammation has been detected in several female reproductive conditions, from anovulation to embryo implantation failure. C-reactive protein (CRP) is a reliable marker of infla...

journal_title：Human reproduction update

authors： Brouillet S,Boursier G,Anav M,Du Boulet De La Boissière B,Gala A,Ferrieres-Hoa A,Touitou I,Hamamah S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The reproductive impact of adenomyosis and endometriosis is widely researched but the extent of these impacts remains elusive. It has been demonstrated that endometriosis, in particular, is known to result in subfertility but endometriosis and adenomyosis are increasingly linked to late pregnancy complicatio...

journal_title：Human reproduction update

authors： Horton J,Sterrenburg M,Lane S,Maheshwari A,Li TC,Cheong Y

更新日期：2019-09-11 00:00:00

abstract：:There has been an improvement in the blastocyst rates achieved following in-vitro embryo production that can largely be attributed to improved embryo culture conditions based on an increased knowledge of the in-vivo environment, as well as the metabolic needs of the embryo. Despite this, in-vitro oocyte maturation (IV...

journal_title：Human reproduction update

authors： Sutton ML,Gilchrist RB,Thompson JG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Human pregnancy requires robust hemostasis to prevent hemorrhage during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification of spiral arteries and post-partum processes. However, decidual hemorrhage (abruption) can occur throughout pregnancy from poorly transformed spiral ar...

journal_title：Human reproduction update

authors： Schatz F,Guzeloglu-Kayisli O,Arlier S,Kayisli UA,Lockwood CJ

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:First-trimester miscarriage affects up to a quarter of women worldwide. With many competing treatment options available, there is a need for a comprehensive evidence synthesis. OBJECTIVES AND RATIONALE:We conducted a systematic review and network meta-analysis to assess the effectiveness and safety of treat...

journal_title：Human reproduction update

authors： H Al Wattar B,Murugesu N,Tobias A,Zamora J,Khan KS

更新日期：2019-05-01 00:00:00

abstract：:Operative hysteroscopy is a relatively new technique that has significantly improved the diagnosis and therapy of abnormal uterine bleeding. At first, the success of operative hysteroscopy in controlling this bleeding seemed extremely high but, with long-term follow-up, a significant failure rate became evident requir...

journal_title：Human reproduction update

authors： McCausland V,McCausland A

更新日期：1998-07-01 00:00:00

abstract：:During the elongating spermatid stage of spermiogenesis, human sperm chromatin undergoes a complex transition in which histones are extensively replaced by protamines in a carefully regulated transition including histone modifications and intermediate and temporary replacement of the histones by sperm-specific transit...

journal_title：Human reproduction update

authors： Carrell DT,Emery BR,Hammoud S

更新日期：2007-05-01 00:00:00

abstract：:We have examined aspects of the fine structure of the basal laminae associated with the luminal and glandular epithelium and small blood vessels in the human endometrium. Four short studies are presented and reviewed. Study 1 examined biopsies from 20 fertile women taken on days after the luteinizing hormone surge (LH...

journal_title：Human reproduction update

authors： Dockery P,Khalid J,Sarani SA,Bulut HE,Warren MA,Li TC,Cooke ID

更新日期：1998-09-01 00:00:00

abstract：:Mammals are generally held to be exceptions to the rule that organization of the egg plays a role in specifying the differentiation of cells, axes, or other aspects of patterning in the early embryo. However, there are several grounds for questioning this conclusion. Not only do certain experimental findings remain un...

journal_title：Human reproduction update

authors： Gardner RL

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Important roles for G-protein-coupled receptors (GPCRs) have been identified in the maternal physiological adaptations to pregnancy and in the pathogenesis of preeclampsia. On this basis, GPCRs are potential therapeutic targets for preeclampsia. OBJECTIVES AND RATIONALE:In this review, vasopressin and apeli...

journal_title：Human reproduction update

authors： Conrad KP

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Reproductive disorders and infertility are associated with the risk of obstetric complications and have a negative impact on pregnancy outcome. Affected patients often require assisted reproductive technologies (ART) to conceive, and advanced maternal age is a further confounding factor. The challenge is to ...

journal_title：Human reproduction update

authors： Vannuccini S,Clifton VL,Fraser IS,Taylor HS,Critchley H,Giudice LC,Petraglia F

更新日期：2016-01-01 00:00:00

abstract：:During the last decade oocyte donation has been highly successful for treating women previously thought to be hopelessly infertile. The pregnancy rate after oocyte donation is among the highest reported for any fertility-enhancing procedure. Most investigators have noted an increased rate of obstetric complications in...

journal_title：Human reproduction update

authors： Söderström-Anttila V

更新日期：2001-01-01 00:00:00

abstract：:Great progress had been achieved during the last 20 years in the field of ovulation induction in patients with polycystic ovary syndrome (PCOS). Clomiphene citrate remains the first line of treatment for all anovulatory women with PCOS, since in properly selected patients the cumulative pregnancy rate approaches that ...

journal_title：Human reproduction update

authors： Messinis IE,Milingos SD

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Thyroid hormone disorders and thyroid peroxidase autoantibodies (TPO-Ab) in women are associated with subfertility and early pregnancy loss. Here, we aim to provide a comprehensive overview of the literature on the pathophysiology of these associations. METHODS:A review of the literature in the English lang...

journal_title：Human reproduction update

authors： Vissenberg R,Manders VD,Mastenbroek S,Fliers E,Afink GB,Ris-Stalpers C,Goddijn M,Bisschop PH

更新日期：2015-05-01 00:00:00

abstract：:Despite recent advances in ovarian stimulation regimens and laboratory techniques, the pregnancy rate of assisted reproduction remains relatively low. New methods that would potentially improve implantation rates are needed. One proposed strategy involves enhancement of blood flow at the implantation site with the use...

journal_title：Human reproduction update

authors： Gelbaya TA,Kyrgiou M,Li TC,Stern C,Nardo LG

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction. METHODS:Specialist reproductive medicine clinicians and geneticists delivered presentations based on published literature and current research. The content of this report i...

journal_title：Human reproduction update

authors： Evian Annual Reproduction (EVAR) Workshop Group 2010.,Fauser BC,Diedrich K,Bouchard P,Domínguez F,Matzuk M,Franks S,Hamamah S,Simón C,Devroey P,Ezcurra D,Howles CM

更新日期：2011-11-01 00:00:00

abstract：:Prior to the development of high-throughput methods for the analysis of differential gene expression, genes required for proper ovarian function were identified on a case-by-case basis. Recently, however, several techniques have been developed that enable investigators to study large-scale changes in gene expression u...

journal_title：Human reproduction update

authors： Hennebold JD

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Genetic testing of preimplantation embryos has been used for preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Microarray technology is being introduced in both these contexts, and whole genome sequencing of blastomeres is also expeted to become possible soon. The amount of...

journal_title：Human reproduction update

authors： Hens K,Dondorp W,Handyside AH,Harper J,Newson AJ,Pennings G,Rehmann-Sutter C,de Wert G

更新日期：2013-07-01 00:00:00

abstract：:Assisted conception is a useful methodology for detecting disturbances in clinical outcome, meiotic maturation, and genetic integrity of human gametes. Germinal cells are vulnerable to genetic damage from smoking, but can repair damage during meiosis. In ejaculated spermatozoa, repair capacity declines drastically. Sm...

journal_title：Human reproduction update

authors： Zenzes MT

更新日期：2000-03-01 00:00:00

abstract：:The examination of fetal cells, specifically erythroblasts, and cell-free fetal DNA from the blood of pregnant women is currently the subject of intense research with the aim of developing new risk-free methods for prenatal diagnosis. An unexpected finding made during these studies was that the traffic of fetal erythr...

journal_title：Human reproduction update

authors： Hahn S,Holzgreve W

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Early during human development, the trophoblast lineage differentiates to commence placentation. Where the placenta contacts the uterine decidua, extravillous trophoblast (EVT) cells differentiate and invade maternal tissues. EVT cells, identified by expression of HLA-G, invade into uterine blood vessels (en...

journal_title：Human reproduction update

authors： Moser G,Drewlo S,Huppertz B,Armant DR

更新日期：2018-07-01 00:00:00

abstract：UNLABELLED:BACKGROUND; Combined oral contraceptives (COCs) reduce levels of androgen, especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by increasing levels of sex hormone-binding globulin (SHBG). Although this suppressive effect has been investigated by numerous studies over many ye...

journal_title：Human reproduction update

authors： Zimmerman Y,Eijkemans MJ,Coelingh Bennink HJ,Blankenstein MA,Fauser BC

更新日期：2014-01-01 00:00:00