Pathophysiological aspects of thyroid hormone disorders/thyroid peroxidase autoantibodies and reproduction.

abstract：BACKGROUND:Infertility is estimated to affect as many as 186 million people worldwide. Although male infertility contributes to more than half of all cases of global childlessness, infertility remains a woman's social burden. Unfortunately, areas of the world with the highest rates of infertility are often those with p...

journal_title：Human reproduction update

authors： Inhorn MC,Patrizio P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The main objective of individualization of treatment in IVF is to offer every single woman the best treatment tailored to her own unique characteristics, thus maximizing the chances of pregnancy and eliminating the iatrogenic and avoidable risks resulting from ovarian stimulation. Personalization of treatmen...

journal_title：Human reproduction update

authors： La Marca A,Sunkara SK

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Although fertility preservation (FP) treatment options have increased, the existing evidence suggests that many women with cancer do not feel well supported in making these decisions, but find them stressful and complex and fail to take up fertility care at this crucial time. Whilst existing reviews have all...

journal_title：Human reproduction update

authors： Jones G,Hughes J,Mahmoodi N,Smith E,Skull J,Ledger W

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Human long non-coding RNAs (lncRNAs) are an emerging category of transcripts with increasingly documented functional roles during development. LncRNAs and roles during human early embryo development have recently begun to be unravelled. OBJECTIVE AND RATIONALE:This review summarizes the most recent knowledg...

journal_title：Human reproduction update

authors： Bouckenheimer J,Assou S,Riquier S,Hou C,Philippe N,Sansac C,Lavabre-Bertrand T,Commes T,Lemaître JM,Boureux A,De Vos J

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength. METHODS:PubMed searches were performed, for studies of the epidemiology of fractures, bone physiology, endocr...

journal_title：Human reproduction update

authors： ESHRE Capri Workshop Group.

更新日期：2010-11-01 00:00:00

abstract：:The results of the Transnational Study on Oral Contraceptives and the Health of Young Women studies are reviewed, potential biases shown, and new analyses are presented. The initial finding was a slight increase in the risk of venous thromboboembolism (VTE) when users of third generation OC (containing the progestins ...

journal_title：Human reproduction update

authors： Lewis MA

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:The use of nuclear transfer (NT) has been proposed as a novel reproductive treatment to overcome the transmission of maternally-inherited mitochondrial DNA (mtDNA) mutations. Pathogenic mutations in mtDNA can cause a wide-spectrum of life-limiting disorders, collectively known as mtDNA disease, for which the...

journal_title：Human reproduction update

authors： Craven L,Tang MX,Gorman GS,De Sutter P,Heindryckx B

更新日期：2017-09-01 00:00:00

abstract：:We have examined aspects of the fine structure of the basal laminae associated with the luminal and glandular epithelium and small blood vessels in the human endometrium. Four short studies are presented and reviewed. Study 1 examined biopsies from 20 fertile women taken on days after the luteinizing hormone surge (LH...

journal_title：Human reproduction update

authors： Dockery P,Khalid J,Sarani SA,Bulut HE,Warren MA,Li TC,Cooke ID

更新日期：1998-09-01 00:00:00

abstract：:Endometriosis is considered primarily a disease of the endometrial-subendometrial unit or archimetra. The clinical picture of endometriosis characterises this disease as a hyperactivation of genuine archimetrial functions such as proliferation, inflammatory defence and peristalsis. While the aetiology of the disease r...

journal_title：Human reproduction update

authors： Leyendecker G,Kunz G,Noe M,Herbertz M,Mall G

更新日期：1998-09-01 00:00:00

abstract：:The use of physical techniques such as scanning electron microscopy and microprobe analysis permits the analysis of valuable details of the structure of dried samples of mid-cycle cervical mucus during the period of maximum ferning. From a crystallographic point of view, particular attention was paid to the location, ...

journal_title：Human reproduction update

authors： Berthou J,Chrétien FC

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:The existence of stem/progenitor cells in the endometrium was postulated many years ago, but the first functional evidence was only published in 2004. The identification of rare epithelial and stromal populations of clonogenic cells in human endometrium has opened an active area of research on endometrial st...

journal_title：Human reproduction update

authors： Gargett CE,Schwab KE,Deane JA

更新日期：2016-03-01 00:00:00

abstract：:The clinical significance of micro-organisms in semen samples of asymptomatic subfertile patients is a matter of constant debate. Usually little attention is paid to anaerobic bacteria as they are sensitive to transportation and culturing, and differentiation is difficult, costly and time-consuming. In the present stu...

journal_title：Human reproduction update

authors： Eggert-Kruse W,Rohr G,Ströck W,Pohl S,Schwalbach B,Runnebaum B

更新日期：1995-09-01 00:00:00

abstract：:Apoptosis is a selective process for deletion of cells in various biological systems. This event, similar to proliferation, is tightly regulated, with both processes playing essential roles in the homeostasis of renewable tissues. In human endometrium, proliferation and apoptosis occur at opposing poles of the menstru...

journal_title：Human reproduction update

authors： Tabibzadeh S

更新日期：1995-07-01 00:00:00

abstract：:BACKGROUND Angiogenesis, i.e. the development of new blood vessels from pre-existing ones, represents an integral part in the pathogenesis of endometriosis. During the last decade, an increasing number of studies have therefore focused on the anti-angiogenic treatment of the disease. The present review provides a syst...

journal_title：Human reproduction update

authors： Laschke MW,Menger MD

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The prevalence of congenital uterine anomalies in high-risk women is unclear, as several different diagnostic approaches have been applied to different groups of patients. This review aims to evaluate the prevalence of such anomalies in unselected populations and in women with infertility, including those un...

journal_title：Human reproduction update

authors： Chan YY,Jayaprakasan K,Zamora J,Thornton JG,Raine-Fenning N,Coomarasamy A

更新日期：2011-11-01 00:00:00

abstract：:During the elongating spermatid stage of spermiogenesis, human sperm chromatin undergoes a complex transition in which histones are extensively replaced by protamines in a carefully regulated transition including histone modifications and intermediate and temporary replacement of the histones by sperm-specific transit...

journal_title：Human reproduction update

authors： Carrell DT,Emery BR,Hammoud S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Activins are members of the pleiotrophic family of the transforming growth factor-beta (TGF-β) superfamily of cytokines, initially isolated for their capacity to induce the release of FSH from pituitary extracts. Subsequent research has demonstrated that activins are involved in multiple biological functions...

journal_title：Human reproduction update

authors： Wijayarathna R,de Kretser DM

更新日期：2016-04-01 00:00:00

abstract：:Single-dose and multiple-rising dose studies of recombinant follicle stimulating hormone (rFSH) in hypogonadotrophic male and female volunteers demonstrated that the rate of FSH absorption after i.m. injection is higher in men than in women. In the absence of endogenous FSH, a correlation between serum FSH and body we...

journal_title：Human reproduction update

authors： Mannaerts BM,Rombout F,Out HJ,Coelingh Bennink H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Clinical trials yield discrepant information about the impact of hormone therapy on verbal memory and executive function. This issue is clinically relevant because declines in verbal memory are the earliest predictor of Alzheimer's disease and declines in executive function are central to some theories of no...

journal_title：Human reproduction update

authors： Maki PM,Sundermann E

更新日期：2009-11-01 00:00:00

abstract：:This review addresses research on gamete donors, recipients, and offspring and demonstrates that the foci on all three within the triad are largely directed at disclosure or anonymity; and each in turn centers on the perceived importance of the genetic link. The importance attached to genetics has led some countries t...

journal_title：Human reproduction update

authors： van den Akker O

更新日期：2006-03-01 00:00:00

abstract：:After colonization of the gonad, mouse female germ cells enter into the prophase of the first meiotic division as a mid-gestational hallmark of gender. Perinatally, oocytes interact with granulosa cells to form primordial follicles which, with cyclic periodicity, enter into a 3-week growth phase that culminates in mei...

journal_title：Human reproduction update

authors： Amleh A,Dean J

更新日期：2002-09-01 00:00:00

abstract：:The use of laparoscopic techniques for the treatment of polycystic ovarian syndrome (PCOS) has included many different approaches in the 1980s and 90s. Broadly similiar results have been obtained using biopsy, cauterization, multi-electrocoagulation and laser surgery; i.e. > 50% ovulation and a mean pregnancy rate of ...

journal_title：Human reproduction update

authors： Cohen J

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Because of the substantial energy demands of reproduction, the brain must temper the fertility of individuals to match nutritional availability. Under-nutrition is associated with infertility in humans and animals. The brain uses adipose- and gut-derived hormones, such as leptin, insulin and ghrelin, to modu...

journal_title：Human reproduction update

authors： Evans JJ,Anderson GM

更新日期：2012-05-01 00:00:00

abstract：:At present, the management of non-organ confined prostate cancer, whether it is a recurrence or metastasis, continues to evolve based on prostate cancer detection using prostate-specific antigen and the development of medications as alternatives for the classical orchiectomy, which induced irreversible implications fo...

journal_title：Human reproduction update

authors： d'Ancona FC,Debruyne FM

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The effect of postmenopausal hormone therapy (HT) on cardiovascular disease (CVD) risk remains controversial. OBJECTIVE AND RATIONALE:We aimed to systematically review the evidence regarding the role of dose, route of hormone administration, timing of initiation and duration of HT on cardiovascular risk amo...

journal_title：Human reproduction update

authors： Oliver-Williams C,Glisic M,Shahzad S,Brown E,Pellegrino Baena C,Chadni M,Chowdhury R,Franco OH,Muka T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:It has been hypothesized that certain obstetrical populations, including women who conceive using assisted reproductive technologies (ART) and women with multiple births, may be at increased risk for postpartum depression. In this systematic literature review, we examine the published evidence for this hypot...

journal_title：Human reproduction update

authors： Ross LE,McQueen K,Vigod S,Dennis CL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) is an arthropod-borne virus of the family Flaviviridae, genus Flavivirus. ZIKV is currently the focus of an ongoing pandemic and worldwide public health emergency. Although originally isolated in 1947, its pathogenesis was poorly known and very few documented infections were published until...

journal_title：Human reproduction update

authors： Epelboin S,Dulioust E,Epelboin L,Benachi A,Merlet F,Patrat C

更新日期：2017-11-01 00:00:00

abstract：:Leiomyomata represent the most common gynaecological tumour in women of reproductive age, and are the primary indication for hysterectomy in the USA. Cytogenetic and genetic studies have, in recent years, advanced our understanding of the aetiology of these tumours. Cytogenetic aberrations involving chromosomes 6, 7, ...

journal_title：Human reproduction update

authors： Ligon AH,Morton CC

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Reproductive disorders and infertility are associated with the risk of obstetric complications and have a negative impact on pregnancy outcome. Affected patients often require assisted reproductive technologies (ART) to conceive, and advanced maternal age is a further confounding factor. The challenge is to ...

journal_title：Human reproduction update

authors： Vannuccini S,Clifton VL,Fraser IS,Taylor HS,Critchley H,Giudice LC,Petraglia F

更新日期：2016-01-01 00:00:00

abstract：:Cancer treatment modalities are increasingly more effective in achieving complete remission and cure. Aggressive chemotherapy and radiotherapy, as well as bone marrow transplantation, results in >90% cure in many cancers of children and young women. As a result of this success however, a new problem has arisen. Many y...

journal_title：Human reproduction update

authors： Oktay K

更新日期：2001-11-01 00:00:00