Can developmentally significant spatial patterning of the egg be discounted in mammals?

abstract：:Nitric oxide (NO) is an important mediator of paracrine interactions, especially within the vascular system. It is a powerful inhibitor of platelet aggregation and a potent vasodilator. NO is also a neurotransmitter and it plays a role in cell-mediated cytotoxicity. NO-generating enzymes (nitric oxide synthases, NOS) ...

journal_title：Human reproduction update

authors： Cameron IT,Campbell S

更新日期：1998-09-01 00:00:00

abstract：:Varicocele is often cited as the most common cause of male factor infertility. Arguments in support of this statement include reports of increased prevalence of varicocele in populations of infertile men compared with fertile or otherwise unselected men, association of varicocele with abnormal semen parameters, and im...

journal_title：Human reproduction update

authors： Redmon JB,Carey P,Pryor JL

更新日期：2002-01-01 00:00:00

abstract：:In the male genital tract, reactive oxygen species (ROS) are generated by spermatozoa and leukocytes including neutrophils and macrophages. ROS are involved in the regulation of sperm functions such as capacitation and the acrosome reaction. Infections lead to an excessive ROS production, resulting in an 'oxidative bu...

journal_title：Human reproduction update

authors： Ochsendorf FR

更新日期：1999-09-01 00:00:00

abstract：:Recent studies suggest a possible link between human assisted reproductive technology and genomic imprinting disorders. Assisted reproductive technology includes the isolation, handling and culture of gametes and early embryos at times when imprinted genes are likely to be particularly vulnerable to external influence...

journal_title：Human reproduction update

authors： Lucifero D,Chaillet JR,Trasler JM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The Fifth Evian Annual Reproduction (EVAR) Workshop Meeting discussed knowledge regarding contemporary genetics in female reproduction. METHODS:Specialist reproductive medicine clinicians and geneticists delivered presentations based on published literature and current research. The content of this report i...

journal_title：Human reproduction update

authors： Evian Annual Reproduction (EVAR) Workshop Group 2010.,Fauser BC,Diedrich K,Bouchard P,Domínguez F,Matzuk M,Franks S,Hamamah S,Simón C,Devroey P,Ezcurra D,Howles CM

更新日期：2011-11-01 00:00:00

abstract：:Contraception is one of the keystones of reproductive health. The availability of effective contraception has helped to change dramatically the structure of the world's population during the last 50 years, through a demographic transition involving lower fertility rates and longer survival. As the transition evolves m...

journal_title：Human reproduction update

authors： ESHRE Capri Workshop Group.

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Approximately half recurrent miscarriage (RM) cases remain unexplained after standard investigations. Secondary RM (SRM) is, in contrast to primary RM, preceded by a birth, which increases the transfer of fetal cells into the maternal circulation. Mothers of boys are often immunized against male-specific min...

journal_title：Human reproduction update

authors： Nielsen HS

更新日期：2011-07-01 00:00:00

abstract：:We have examined aspects of the fine structure of the basal laminae associated with the luminal and glandular epithelium and small blood vessels in the human endometrium. Four short studies are presented and reviewed. Study 1 examined biopsies from 20 fertile women taken on days after the luteinizing hormone surge (LH...

journal_title：Human reproduction update

authors： Dockery P,Khalid J,Sarani SA,Bulut HE,Warren MA,Li TC,Cooke ID

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Threatened miscarriage affects one in five women and is associated with significant emotional distress. The uncertainty around the prognosis of threatened miscarriage makes it equally challenging to the healthcare professionals. Various biochemical markers have been investigated in the past to predict the ou...

journal_title：Human reproduction update

authors： Pillai RN,Konje JC,Tincello DG,Potdar N

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Although fertility preservation (FP) treatment options have increased, the existing evidence suggests that many women with cancer do not feel well supported in making these decisions, but find them stressful and complex and fail to take up fertility care at this crucial time. Whilst existing reviews have all...

journal_title：Human reproduction update

authors： Jones G,Hughes J,Mahmoodi N,Smith E,Skull J,Ledger W

更新日期：2017-07-01 00:00:00

abstract：:Mammalian oocytes begin meiosis in the fetal ovary, but only complete it when fertilized in the adult reproductive tract. This review examines the cell biology of this protracted process: from entry of primordial germ cells into meiosis to conception. The defining feature of meiosis is two consecutive cell divisions (...

journal_title：Human reproduction update

authors： Jones KT

更新日期：2008-03-01 00:00:00

abstract：:Syncytin is a membrane protein derived from the envelope gene of an endogenous retrovirus of the HERV-W family. The gene appears to be almost exclusively expressed in placenta; the protein was found in particular in syncytiotrophoblast. After transfection into various cell types it has proven to be a very fusogenic pr...

journal_title：Human reproduction update

authors： Pötgens AJ,Drewlo S,Kokozidou M,Kaufmann P

更新日期：2004-11-01 00:00:00

abstract：:Maternal use of marijuana, in which the exocannabinoid Delta(9)-tetrahydrocannabinol is the most active psychoactive ingredient, is known to have adverse effects on various aspects of reproduction including ovulation, spermatogenesis, implantation and pregnancy duration. Endogenous cannabinoids of which Anandamide is ...

journal_title：Human reproduction update

authors： Taylor AH,Ang C,Bell SC,Konje JC

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:The aim of this meta-analysis was to investigate whether any difference exists in success rate of clinical outcomes of assisted reproductive technologies (ART) between women who actively smoke cigarettes at the time of treatment and those who do not. METHODS:An intensive computerized search was conducted on...

journal_title：Human reproduction update

authors： Waylen AL,Metwally M,Jones GL,Wilkinson AJ,Ledger WL

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Recurrent pregnancy loss (RPL) occurs in 1-3% of all couples trying to conceive. No consensus exists regarding when to perform testing for risk factors in couples with RPL. Some guidelines recommend testing if a patient has had two pregnancy losses whereas others advise to test after three losses. OBJECTIVE...

journal_title：Human reproduction update

authors： van Dijk MM,Kolte AM,Limpens J,Kirk E,Quenby S,van Wely M,Goddijn M

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Fear from increased cancer risk is one of the most significant reasons for low acceptance of reliable contraceptive methods and low compliance. METHODS:In this review, we included all cohort and case-control studies published in English up to December 2008. They were identified through a search of the liter...

journal_title：Human reproduction update

authors： Cibula D,Gompel A,Mueck AO,La Vecchia C,Hannaford PC,Skouby SO,Zikan M,Dusek L

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Every year 30% of individuals above age 65 fall, and falls are the principal cause of bone fractures. To reduce fracture incidence requires both prevention of falls and maintenance of bone strength. METHODS:PubMed searches were performed, for studies of the epidemiology of fractures, bone physiology, endocr...

journal_title：Human reproduction update

authors： ESHRE Capri Workshop Group.

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:With the recent development of CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 genome editing technology, the possibility to genetically manipulate the human germline (gametes and embryos) has become a distinct technical possibility. Although many technical challenges still need to be...

journal_title：Human reproduction update

authors： Vassena R,Heindryckx B,Peco R,Pennings G,Raya A,Sermon K,Veiga A

更新日期：2016-06-01 00:00:00

abstract：:This review addresses research on gamete donors, recipients, and offspring and demonstrates that the foci on all three within the triad are largely directed at disclosure or anonymity; and each in turn centers on the perceived importance of the genetic link. The importance attached to genetics has led some countries t...

journal_title：Human reproduction update

authors： van den Akker O

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Mast cells (MCs) are the classical mediators of allergy, however, their importance in the development of innate and adaptive immune responses is increasingly being recognized. Herein, the present MC literature is summarized, with particular focus on studies of MCs in the endometrium and myometrium, and their...

journal_title：Human reproduction update

authors： Menzies FM,Shepherd MC,Nibbs RJ,Nelson SM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Androgens, FSH, anti-Müllerian hormone (AMH) and estradiol (E2) are essential in human ovarian folliculogenesis. However, the interactions between these four players is not fully understood. OBJECTIVES AND RATIONALE:The purpose of this review is to highlight the chronological sequence of the appearance and ...

journal_title：Human reproduction update

authors： Dewailly D,Robin G,Peigne M,Decanter C,Pigny P,Catteau-Jonard S

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:It has been hypothesized that certain obstetrical populations, including women who conceive using assisted reproductive technologies (ART) and women with multiple births, may be at increased risk for postpartum depression. In this systematic literature review, we examine the published evidence for this hypot...

journal_title：Human reproduction update

authors： Ross LE,McQueen K,Vigod S,Dennis CL

更新日期：2011-01-01 00:00:00

abstract：:The examination of fetal cells, specifically erythroblasts, and cell-free fetal DNA from the blood of pregnant women is currently the subject of intense research with the aim of developing new risk-free methods for prenatal diagnosis. An unexpected finding made during these studies was that the traffic of fetal erythr...

journal_title：Human reproduction update

authors： Hahn S,Holzgreve W

更新日期：2002-11-01 00:00:00

abstract：:The improved long-term survival of adolescents and young women treated for cancer has resulted in an increased focus on the effects of chemotherapy on ovarian function and its preservation. These women may seek advice and treatment regarding their reproductive status, including ways of preserving their fertility and p...

journal_title：Human reproduction update

authors： Lutchman Singh K,Davies M,Chatterjee R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Genetic testing of preimplantation embryos has been used for preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS). Microarray technology is being introduced in both these contexts, and whole genome sequencing of blastomeres is also expeted to become possible soon. The amount of...

journal_title：Human reproduction update

authors： Hens K,Dondorp W,Handyside AH,Harper J,Newson AJ,Pennings G,Rehmann-Sutter C,de Wert G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Spermatogenesis culminates in production of one of the most highly differentiated cells in biology, the spermatozoon. The gametes that emerge from the testes are, however, functionally immature and only acquire full functionality once they have completed a process of post-testicular maturation in the epididy...

journal_title：Human reproduction update

authors： Dun MD,Aitken RJ,Nixon B

更新日期：2012-07-01 00:00:00

abstract：:The effects on reproductive tract development in male rats, of neonatal exposure to potent (reference) oestrogens, diethylstilboestrol (DES) and ethinyl oestradiol (EE), with those of two environmental oestrogens, octylphenol and hisphenol A were systematically compared. Other treatments, such as administration of a g...

journal_title：Human reproduction update

authors： Williams K,McKinnell C,Saunders PT,Walker M,Fisher JS,Turner KJ,Atanassova N,Sharpe M

更新日期：2001-05-01 00:00:00

abstract：:Single-dose and multiple-rising dose studies of recombinant follicle stimulating hormone (rFSH) in hypogonadotrophic male and female volunteers demonstrated that the rate of FSH absorption after i.m. injection is higher in men than in women. In the absence of endogenous FSH, a correlation between serum FSH and body we...

journal_title：Human reproduction update

authors： Mannaerts BM,Rombout F,Out HJ,Coelingh Bennink H

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Early during human development, the trophoblast lineage differentiates to commence placentation. Where the placenta contacts the uterine decidua, extravillous trophoblast (EVT) cells differentiate and invade maternal tissues. EVT cells, identified by expression of HLA-G, invade into uterine blood vessels (en...

journal_title：Human reproduction update

authors： Moser G,Drewlo S,Huppertz B,Armant DR

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Despite great advances in assisted reproductive technology, poor ovarian response (POR) is still considered as one of the most challenging tasks in reproductive medicine. OBJECTIVE AND RATIONALE:The aim of this systemic review is to evaluate the role of different adjuvant treatment strategies on the probabi...

journal_title：Human reproduction update

authors： Zhang Y,Zhang C,Shu J,Guo J,Chang HM,Leung PCK,Sheng JZ,Huang H

更新日期：2020-02-28 00:00:00