The evolution of neuronal circuits underlying species-specific behavior.

abstract：:A number of laboratories have recently refined descriptions of temporal response properties, from the auditory periphery to the midbrain. At many levels of the auditory pathway, the role of inhibition in temporal coding of complex sounds is being explored. In addition, quantitative relationships between physiology and...

journal_title：Current opinion in neurobiology

authors： Carney LH

更新日期：1999-08-01 00:00:00

abstract：:The idea that visual signals relayed by the parvocellular and magnocellular subdivisions of the lateral geniculate nucleus remain segregated in the cerebral cortex has attracted considerable attention. It has been proposed that parvocellular contributions dominate in the temporal visual cortex, and that magnocellular ...

journal_title：Current opinion in neurobiology

authors： Maunsell JH

更新日期：1992-08-01 00:00:00

abstract：:Synapses are specialized sites of cell contact that mediate information flow between neurons and their targets. Genetic screens in the nematode C. elegans have led to the discovery of a number of molecules required for synapse patterning and assembly. Recent studies have demonstrated the importance of guidepost cells ...

journal_title：Current opinion in neurobiology

authors： Margeta MA,Shen K,Grill B

更新日期：2008-02-01 00:00:00

abstract：:Homeostatic synaptic plasticity remains an enigmatic form of synaptic plasticity. Increasing interest on the topic has fuelled a surge of recent studies that have identified key molecular players and the signaling pathways involved. However, the new findings also highlight our lack of knowledge concerning some of the ...

journal_title：Current opinion in neurobiology

authors： Vitureira N,Letellier M,Goda Y

更新日期：2012-06-01 00:00:00

abstract：:Comparative studies over the past year have revealed two new insights into the role of neuropeptides in the evolution of social behaviors. First, across vertebrate taxa, certain neuropeptide effects appear to be gender-specific. Second, species variations in receptor gene structure can alter neuropeptide receptor dist...

journal_title：Current opinion in neurobiology

authors： Insel TR,Young LJ

更新日期：2000-12-01 00:00:00

abstract：:Cyclic nucleotide gated (CNG) cation channels are critical for signal transduction in vertebrate visual and olfactory systems. Members of the CNG channel gene family have now been cloned from a number of species, from Caenorhabditis elegans to humans. An important advance has been the discovery that CNG channels are p...

journal_title：Current opinion in neurobiology

authors： Zufall F,Shepherd GM,Barnstable CJ

更新日期：1997-06-01 00:00:00

abstract：:Recent studies show that anatomical and functional brain networks exhibit similar small-world properties. However, the networks that are compared often differ in what the nodes represent (e.g. sensors or brain areas), what kind of connectivity is measured, and what temporal and spatial scales are probed. Here, I revie...

journal_title：Current opinion in neurobiology

authors： Ioannides AA

更新日期：2007-04-01 00:00:00

abstract：:Chronic administration of opiates or cocaine has been shown to alter the activity or expression of diverse types of cellular proteins in specific target neurons within the central nervous system. Prominent examples include signaling proteins, such as receptors, G proteins, second-messenger synthetic enzymes, and prote...

journal_title：Current opinion in neurobiology

authors： Nestler EJ

更新日期：1997-10-01 00:00:00

abstract：:The generation of a functional neuronal network requires that axons navigate precisely to their appropriate targets. Molecules that specify guidance decisions have been identified, and the signaling events that occur downstream of guidance receptors are beginning to be understood. New research shows that guidance rece...

journal_title：Current opinion in neurobiology

authors： Grunwald IC,Klein R

更新日期：2002-06-01 00:00:00

abstract：:Phototransduction in Drosophila's microvillar photoreceptors is mediated by phospholipase C (PLC) resulting in activation of two distinct Ca(2+)-permeable channels, TRP and TRPL. Here we review recent evidence on the unresolved mechanism of their activation, including the hypothesis that the channels are mechanically ...

journal_title：Current opinion in neurobiology

authors： Hardie RC,Juusola M

更新日期：2015-10-01 00:00:00

abstract：:The gene product responsible for autosomal recessive juvenile Parkinsonism, Parkin, has been observed to have ubiquitin ligase activity. This finding has changed the direction of studies on Parkinson's disease by suggesting that abnormal protein turnover might be involved in its pathogenesis. A number of potentially n...

journal_title：Current opinion in neurobiology

authors： Imai Y,Takahashi R

更新日期：2004-06-01 00:00:00

abstract：:The prominent view that the rodent hippocampus is dedicated to spatial memory has been challenged recently by observations that both limit the nature of hippocampal spatial representation and extend its scope beyond literal space. These findings reveal that the rodent hippocampus mediates memory representations on the...

journal_title：Current opinion in neurobiology

authors： Eichenbaum H

更新日期：1996-04-01 00:00:00

abstract：:The established function of oligodendrocytes and their progenitors is to drive the cellular events of myelination, a highly diversified process necessary to match the needs of various neuronal subtypes and networks. The morphological and molecular heterogeneity of oligodendrocytes and their progenitors point to functi...

journal_title：Current opinion in neurobiology

authors： Dimou L,Simons M

更新日期：2017-12-01 00:00:00

abstract：:Delineating the lineage of neural cells that captures the progressive steps in their specification is fundamental to understanding brain development, organization, and function. Since the earliest days of embryology, lineage questions have been addressed with methods of increasing specificity, capacity, and resolution...

journal_title：Current opinion in neurobiology

authors： Ma J,Shen Z,Yu YC,Shi SH

更新日期：2018-06-01 00:00:00

abstract：:Sex steroid hormones exert a profound influence on the sexual differentiation and function of the neural circuits that mediate dimorphic behaviors. Both estrogen and testosterone are essential for male typical behaviors in many species. Recent studies with genetically modified mice provide important new insights into ...

journal_title：Current opinion in neurobiology

authors： Wu MV,Shah NM

更新日期：2011-02-01 00:00:00

abstract：:Myelin sheaths in the vertebrate nervous system enable faster impulse propagation, while myelinating glia provide vital support to axons. Once considered a static insulator, converging evidence now suggests that myelin in the central nervous system can be dynamically regulated by neuronal activity and continues to par...

journal_title：Current opinion in neurobiology

authors： Kaller MS,Lazari A,Blanco-Duque C,Sampaio-Baptista C,Johansen-Berg H

更新日期：2017-12-01 00:00:00

abstract：:A diverse group of biochemically distinct proteins give rise to amyloids, each of which is associated with a different disease. These amyloid proteins share numerous properties and typically arise from the abnormal processing of an amyloid precursor protein. The classification, mechanisms and biochemistry of amyloid f...

journal_title：Current opinion in neurobiology

authors： Castaño EM,Wisniewski T,Frangione B

更新日期：1991-10-01 00:00:00

abstract：:Connections and interactions among distributed brain areas are increasingly recognized as the basis for cognitive operations and a diverse repertoire of behaviors. Analytic advances have allowed for brain connectivity to be represented and quantified at multiple levels: from single connections to communities and netwo...

journal_title：Current opinion in neurobiology

authors： Mišić B,Sporns O

更新日期：2016-10-01 00:00:00

abstract：:Voltage-gated ion channels are composed of pore-forming subunits, as well as auxiliary subunits that modify the functions of these channels. In addition, the channels interact with other modulatory proteins in a more transient manner, although with significant effects on channel activity. Even though many second-messe...

journal_title：Current opinion in neurobiology

authors： Adelman JP

更新日期：1995-06-01 00:00:00

abstract：:The study of plasticity in the central nervous system is a major and very dynamic neuroscience research field with enormous clinical potential. Considerable advances in this field have been made during the past 10 years. It now appears that most circuits in the brain and spinal cord show plasticity and that they can b...

journal_title：Current opinion in neurobiology

authors： Schouenborg J

更新日期：2004-12-01 00:00:00

abstract：:Genetic mosaic techniques provide a powerful tool for dissecting gene function in the intricate genetic networks that underlie the formation and function of nervous systems. For instance, it is possible to make individual cells or groups of cells homozygous for mutations of interest at specific points during an organi...

journal_title：Current opinion in neurobiology

authors： Zugates CT,Lee T

更新日期：2004-10-01 00:00:00

abstract：:Six highly temperature-sensitive ion channels of the transient receptor potential (TRP) family have been implicated to mediate temperature sensation. These channels, expressed in sensory neurons innervating the skin or the skin itself, are active at specific temperatures ranging from noxious cold to burning heat. In a...

journal_title：Current opinion in neurobiology

authors： Bandell M,Macpherson LJ,Patapoutian A

更新日期：2007-08-01 00:00:00

abstract：:Neuropeptide Y is an important regulator of energy intake and expenditure. The central portion of this regulatory system appears to reside in the arcuate nucleus/paraventricular nucleus of the hypothalamus. The effects of neuropeptide Y on energy metabolism include increased food intake, decreased thermogenesis and in...

journal_title：Current opinion in neurobiology

authors： Billington CJ,Levine AS

更新日期：1992-12-01 00:00:00

abstract：:Adult somatic stem cells are generally defined as cells with the ability to differentiate into multiple different lineages and to self-renew during long periods of time. These features were long presumed to be represented in one single tissue-specific stem cell. Recent development of single-cell technologies reveals t...

journal_title：Current opinion in neurobiology

authors： Llorens-Bobadilla E,Martin-Villalba A

更新日期：2017-02-01 00:00:00

abstract：:Facial interactions are prominent behaviors in primates. Primate facial signaling, which includes the expression of emotions, mimicking of facial movements, and gaze interactions, is visually dominated. Correspondingly, in primate brains an elaborate network of face processing areas exists within visual cortex. But ot...

journal_title：Current opinion in neurobiology

authors： Brecht M,Freiwald WA

更新日期：2012-04-01 00:00:00

abstract：:Powerful advances in neuroimaging techniques have added to and refined classical descriptions of the neurobiology of language in adults. Recent studies have employed these methodologies to study the nature and extent of plasticity of language-relevant aspects of cerebral organization in adults, in early and late bilin...

journal_title：Current opinion in neurobiology

authors： Neville HJ,Bavelier D

更新日期：1998-04-01 00:00:00

abstract：:Reward valuation in social contexts is by nature relative rather than absolute; it is made in reference to others. This socially relative reward valuation is based on our propensity to conduct comparisons and competitions between self and other. Exploring its neural substrate has been an active area of research in hum...

journal_title：Current opinion in neurobiology

authors： Isoda M

更新日期：2020-12-08 00:00:00

abstract：:Reinforcement learning provides both qualitative and quantitative frameworks for understanding and modeling adaptive decision-making in the face of rewards and punishments. Here we review the latest dispatches from the forefront of this field, and map out some of the territories where lie monsters. ...

journal_title：Current opinion in neurobiology

authors： Dayan P,Niv Y

更新日期：2008-04-01 00:00:00

abstract：:Canonically, 'mirror neurons' are cells in area F5 of the ventral premotor cortex that are active during both observation and execution of goal-directed movements. Recently, cells with similar properties have been observed in a number of other areas in the motor system, including the primary motor cortex. Mirror neuro...

journal_title：Current opinion in neurobiology

authors： Tkach D,Reimer J,Hatsopoulos NG

更新日期：2008-12-01 00:00:00

abstract：:Sensory neurons are usually described with an encoding model, for example, a function that predicts their response from the sensory stimulus using a receptive field (RF) or a tuning curve. However, central to theories of sensory processing is the notion of 'efficient coding'. We argue here that efficient coding implie...

journal_title：Current opinion in neurobiology

authors： Deneve S,Chalk M

更新日期：2016-04-01 00:00:00