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Systemic mastocytosis: MRI of bone marrow involvement.

Abstract：

:Systemic mastocytosis (SM) is an abnormal proliferation of mast cells, located in different structures: skin, bone marrow, spleen, liver and lymph nodes. Magnetic resonance imaging was prospectively performed in ten patients diagnosed by bone marrow biopsy in order to describe the different patterns of bone marrow involvement. Coronal T1-weighted spin-echo images were obtained in vertebral, pelvic, humeral and femoral bones. Depending on the extension of the cell infiltration, three patterns of bone marrow involvement were used: normal/no involvement (N), non-homogeneous (NH) and homogeneous (H). All ten patients presented bone infiltration. The patterns observed were: spine (50 % NH, 50 % H), pelvis (70 % NH), humerus 100(NH) and femur 40 % (NH). T1-weighted MR imaging is a sensitive technique for detecting marrow abnormalities in patients with systemic mastocytosis. There is no correlation between percentage of mast cells in bone marrow biopsy and extent or pattern of bone marrow involvement.

journal_name

Eur Radiol

journal_title

European radiology

authors

Roca M,Mota J,Giraldo P,García Erce JA

doi

10.1007/s003300050796

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

1094-7

issue

6

eissn

0938-7994

issn

1432-1084

pii

90091094.330

journal_volume

9

pub_type

杂志文章

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